Allen M. Spiegel

Medicine

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Allen M. Spiegel

• Departments
  Medicine
  
  

718-430-2801

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Allen M. Spiegel; Meredith Hawkins

  'Personalized medicine' to identify genetic risks for type 2 diabetes and focus prevention: Can it fulfill its promise?

  Health Affairs. 2012;31(1):43-49.
  1

• 2.

  2011

  Allen M. Spiegel; Steven K. Libutti

  Good news for advanced-stage pancreatic neuroendocrine tumors

  Nature Reviews Clinical Oncology. 2011;8(5):258-259.
  0

• 3.

  2010

  Allen M. Spiegel; Steven K. Libutti

  Future diagnostic and therapeutic trends in endocrine cancers

  Seminars in Oncology. 2010;37(6):691-695.
  1

• 4.

  2010

  Allen M. Spiegel

  Commentary: New guidelines for nih peer review: Improving the system or undermining it?

  Academic Medicine. 2010;85(5):746-748.
  0

• 5.

  2009

  H.-C. Jennifer Shen; Mei He; Anathea Powell; Asha Adem; Dominique Lorang; Charles Heller; Amelia C Grover; Kris Ylaya; Stephen M. Hewitt; Stephen J. Marx; et al.

  Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of men 1

  Cancer Research. 2009;69(5):1858-1866.
  14

• 6.

  2008

  Allen Spiegel

  Albert Einstein College of Medicine.

  Academic medicine : journal of the Association of American Medical Colleges. 2008;83(5):524.
  0

• 7.

  2008

  H.-C. Jennifer Shen; Jennifer E. Rosen; Lauren M. Yang; Sharon A. Savage; A. Lee Burns; Carmen M. Mateo; Sunita K. Agarwal; Settara C. Chandrasekharappa; Allen M. Spiegel; Francis S. Collins; et al.

  Parathyroid tumor development involves deregulation of homeobox genes

  Endocrine-Related Cancer. 2008;15(1):267-275.
  18

• 8.

  2007

  Jianxin Hu; Allen M. Spiegel

  Structure and function of the human calcium-sensing receptor: Insights from natural and engineered mutations and allosteric modulators: Ca2+-Sensing Receptor Review Series

  Journal of Cellular and Molecular Medicine. 2007;11(5):908-922.
  38

• 9.

  2007

  Atsushi Ozawa; Sunita K. Agarwal; Carmen M. Mateo; A. Lee Burns; Terri S. Rice; Patricia A. Kennedy; Caitlin M. Quigley; William F. Simonds; Lee S. Weinstein; Settara C. Chandrasekharappa; et al.

  The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27^Kip1 mutations

  Journal of Clinical Endocrinology and Metabolism. 2007;92(5):1948-1951.
  38

• 10.

  2007

  Jianxin Hu; Guadalupe Reyes-Cruz; Paul K. Goldsmith; Nicole M. Gantt; Jeffery L. Miller; Allen M. Spiegel

  Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca²⁺ receptor

  Journal of Bone and Mineral Research. 2007;22(4):601-608.
  7

• 11.

  2007

  Sunita K. Agarwal; Soren Impey; Shannon McWeeney; Peter C. Scacheri; Francis S. Collins; Richard H. Goodman; Allen M. Spiegel; Stephen J. Marx

  Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation

  Neoplasia. 2007;9(2):101-107.
  28

• 12.

  2007

  Nina Wettschureck; EunAh Lee; Steven K. Libutti; Stefan Offermanns; Pamela G. Robey; Allen M. Spiegel

  Parathyroid-specific double knockout of G_q and G₁₁ α-subunits leads to a phenotype resembling germline knockout of the extracellular Ca²⁺-sensing receptor

  Molecular Endocrinology. 2007;21(1):274-280.
  20

• 13.

  2007

  A. Spiegel

  Inherited endocrine diseases involving G proteins and G protein-coupled receptors

  Endocrine Development. 2007;11:133-144.
  4

• 14.

  2006

  Aniello Cerrato; Michael Parisi; Sonia Santa Anna; Fanis Missirlis; Siradanahalli Guru; Sunita Agarwal; David Sturgill; Thomas Talbot; Allen Spiegel; Francis Collins; et al.

  Genetic interactions between Drosophila melanogaster menin and Jun/Fos

  Developmental Biology. 2006;298(1):59-70.
  7

• 15.

  2006

  Jianxin Hu; Jiankang Jiang; Stefano Costanzi; Craig Thomas; Wu Yang; Jean H. M. Feyen; Kenneth A. Jacobson; Allen M. Spiegel

  A missense mutation in the seven-transmembrane domain of the human Ca ²⁺ receptor converts a negative allosteric modulator into a positive allosteric modulator

  Journal of Biological Chemistry. 2006;281(30):21558-21565.
  25

• 16.

  2006

  Peter C Scacheri; Sean Davis; Duncan T Odom; Gregory E Crawford; Stacie Perkins; Mohamad J Halawi; Sunita K Agarwal; Stephen J Marx; Allen M Spiegel; et al.

  Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.

  PLoS genetics. 2006;2(4):e51.
  57

• 17.

  2006

  Allen M. Spiegel; Elizabeth G. Nabel

  NIH research on obesity and type 2 diabetes: Providing the scientific evidence base for actions to improve health

  Nature Medicine. 2006;12(1):67-69.
  4

• 18.

  2005

  Allen M Spiegel; Barbara M Alving

  Executive summary of the Strategic Plan for National Institutes of Health Obesity Research.

  The American journal of clinical nutrition. 2005;82(1 Suppl):211S-214S.
  16

• 19.

  2005

  S.K. Agarwal; P.A. Kennedy; P.C. Scacheri; E.A. Novotny; A.B. Hickman; A. Cerrato; T.S. Rice; J.B. Moore; S. Rao; Y. Ji; et al.

  Menin molecular interactions: Insights into normal functions and tumorigenesis

  Hormone and Metabolic Research. 2005;37(6):369-374.
  65

• 20.

  2005

  Jennifer E Rosen; Nick G Costouros; Dominique Lorang; A Lee Burns; H Richard Alexander; Monica C Skarulis; Craig Cochran; James F Pingpank; Stephen J Marx; et al.

  Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas.

  Annals of surgical oncology : the official journal of the Society of Surgical Oncology. 2005;12(5):412-416.
  1

• 21.

  2005

  Allen Spiegel; Elizabeth Nabel; Nora Volkow; Story Landis; Ting-Kai Li

  Obesity on the brain

  Nature Neuroscience. 2005;8(5):552-553.
  19

• 22.

  2005

  Charles O. Elson; Martha Ballew; John A. Barnard; Steven J. Bernstein; Irene J. Check; Mitchell B. Cohen; Sara Fazio; John F. Johanson; Noralane M. Lindor; Elizabeth Montgomery; et al.

  National Institutes of Health Consensus Development Conference statement on Celiac Disease, June 28-30, 2004

  Gastroenterology. 2005;128(4 SUPPL. 1):S1-S9.
  60

• 23.

  2005

  Jianxin Hu; Stuart J. McLarnon; Stefano Mora; Jiankang Jiang; Craig Thomas; Kenneth A. Jacobson; Allen M. Spiegel

  A region in the seven-transmembrane domain of the human Ca²⁺ receptor critical for response to Ca²⁺

  Journal of Biological Chemistry. 2005;280(6):5113-5120.
  43

• 24.

  2004

  Peter C. Scacheri; Judy S. Crabtree; Alyssa L. Kennedy; Gary P. Swain; Jerrold M. Ward; Stephen J. Marx; Allen M. Spiegel; Francis S. Collins

  Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1

  Mammalian Genome. 2004;15(11):872-877.
  24

• 25.

  2004

  Peter C. Scacheri; Alyssa L. Kennedy; Koei Chin; Meghan T. Miller; J. Graeme Hodgson; Joe W. Gray; Stephen J. Marx; Allen M. Spiegel; Francis S. Collins

  Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability

  Cancer Research. 2004;64(19):7039-7044.
  15

• 26.

  2004

  Allen M. Spiegel

  Focus on hereditary endocrine neoplasia

  Cancer Cell. 2004;6(4):327-332.
  3

• 27.

  2004

  Jianxin Hu; Stefano Mora; Giovanna Weber; Ilaria Zamproni; Maria Carla Proverbio; Allen M. Spiegel

  Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the amino-terminus of the human calcium receptor

  Journal of Bone and Mineral Research. 2004;19(4):578-586.
  13

• 28.

  2004

  Allen M. Spiegel; Lee S. Weinstein

  Inherited diseases involving G proteins and G protein-coupled receptors

  Annual Review of Medicine. 2004;55:27-39.
  124

• 29.

  2004

  Sunita K. Agarwal; A. Lee Burns; Karen E. Sukhodolets; Patricia A. Kennedy; Victor H. Obungu; Alison B. Hickman; Michael E. Mullendore; Ira Whitten; Monica C. Skarulis; William F. Simonds; et al.

  Molecular pathology of the MEN1 gene

  Annals of the New York Academy of Sciences. 2004;1014:189-198.
  84

• 30.

  2003

  Steven K. Libutti; Judy S. Crabtree; Dominique Lorang; A. Lee Burns; Chiara Mazzanti; Stephen M. Hewitt; Sarah O'Connor; Jerrold M. Ward; Michael R. Emmert-Buck; Alan Remaley; et al.

  Parathyroid Gland-specific Deletion of the Mouse Men1 Gene Results in Parathyroid Neoplasia and Hypercalcemic Hyperparathyroidism

  Cancer Research. 2003;63(22):8022-8028.
  32

• 31.

  2003

  Sunita K. Agarwal; Elizabeth A. Novotny; Judy S. Crabtree; Jonathan B. Weitzman; Moshe Yaniv; A. Lee Burns; Settara C. Chandrasekharappa; Francis S. Collins; Allen M. Spiegel; et al.

  Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter

  Proceedings of the National Academy of Sciences of the United States of America. 2003;100(19):10770-10775.
  64

• 32.

  2003

  Allen Spiegel

  β-arrestin - Not just for G protein-coupled receptors

  Science. 2003;301(5638):1338-1339.
  9

• 33.

  2003

  Judy S. Crabtree; Peter C. Scacheri; Jerrold M. Ward; Sara R. McNally; Gary P. Swain; Cristina Montagna; Jeffrey H. Hager; Douglas Hanahan; Helena Edlund; Mark A. Magnuson; et al.

  Of mice and MEN1: Insulinomas in a conditional mouse knockout

  Molecular and Cellular Biology. 2003;23(17):6075-6085.
  86

• 34.

  2003

  Jianxin Hu; Allen M. Spiegel

  Naturally occurring mutations of the extracellular Ca²⁺-sensing receptor: Implications for its structure and function

  Trends in Endocrinology and Metabolism. 2003;14(6):282-288.
  72

• 35.

  2003

  Karen E. Sukhodolets; Alison B. Hickman; Sunita K. Agarwal; Maxim V. Sukhodolets; Victor H. Obungu; Elizabeth A. Novotny; Judy S. Crabtree; Settara C. Chandrasekharappa; Francis S. Collins; et al.

  The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene

  Molecular and Cellular Biology. 2003;23(2):493-509.
  83

• 36.

  2002

  Jianxin Hu; Guadalupe Reyes-Cruz; Wangzhong Chen; Kenneth A. Jacobson; Allen M. Spiegel

  Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca²⁺ receptor critical for response to Ca²⁺ and a positive allosteric modulator

  Journal of Biological Chemistry. 2002;277(48):46622-46631.
  56

• 37.

  2002

  Stephen J. Marx; William F. Simonds; Sunita K. Agarwal; A. Lee Burns; Lee S. Weinstein; Craig Cochran; Monica C. Skarulis; Allen M. Spiegel; Steven K. Libutti; H. Richard Alexander Jr.; et al.

  Hyperparathyroidism in hereditary syndromes: Special expressions and special managements

  Journal of Bone and Mineral Research. 2002;17(SUPPL. 2):N37-N43.
  81

• 38.

  2002

  Jianxin Hu; Stefano Mora; Giacomo Colussi; Maria Carla Proverbio; Kendra A. Jones; Laura Bolzoni; Maria E. De Ferrari; Giovanni Civati; Allen M. Spiegel

  Autosomal dominant hypocalcemia caused by a novel mutation in the loop 2 region of the human calcium receptor extracellular domain

  Journal of Bone and Mineral Research. 2002;17(8):1461-1469.
  17

• 39.

  2001

  Guadalupe Reyes-Cruz; Jianxin Hu; Paul K. Goldsmith; Peter J. Steinbach; Allen M. Spiegel

  Human Ca²⁺ receptor extracellular domain. Analysis of function of lobe I loop deletion mutants

  Journal of Biological Chemistry. 2001;276(34):32145-32151.
  17

• 40.

  2001

  Christina Heppner; Karl Y. Bilimoria; Sunita K. Agarwal; MaryBeth Kester; Leslie J. Whitty; Siradanahalli C. Guru; Settara C. Chandrasekharappa; Francis S. Collins; Allen M. Spiegel; Stephen J Marx; et al.

  The tumor suppressor protein menin interacts with NF-κB proteins and inhibits NF-κB-mediated transactivation

  Oncogene. 2001;20(36):4917-4925.
  146

• 41.

  2001

  Jianxin Hu; Guadalupe Reyes-Cruz; Paul K. Goldsmith; Allen M. Spiegel

  The Venus's-flytrap and Cysteine-rich Domains of the Human Ca²⁺ Receptor are Not Linked by Disulfide Bonds

  Journal of Biological Chemistry. 2001;276(10):6901-6904.
  15

• 42.

  2001

  Judy S. Crabtree; Peter C. Scacheri; Jerrold M. Ward; Lisa Garrett-Beal; Michael R. Emmert-Buck; Keith A. Edgemon; Dominique Lorang; Steven K. Libutti; Settara C. Chandrasekharappa; et al.

  A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

  Proceedings of the National Academy of Sciences of the United States of America. 2001;98(3):1118-1123.
  225

• 43.

  2001

  Siradanahalli C. Guru; Nijaguna B. Prasad; Eun J. Shin; Kirugaval Hemavathy; Jining Lu; Y.Tony Ip; Sunita K. Agarwal; Stephen J. Marx; Allen M. Spiegel; et al.

  Characterization of a MEN1 ortholog from Drosophila melanogaster

  Gene. 2001;263(1-2):31-38.
  24

• 44.

  2001

  P.C. Scacheri; J.S. Crabtree; E.A. Novotny; L. Garrett-Beal; A. Chen; K.A. Edgemon; S.J. Marx; A.M. Spiegel; S.C. Chandrasekharappa; F.S. Collins

  Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice

  Genesis. 2001;30(4):259-263.
  41

• 45.

  2001

  M.A. Valle; M.B. Kester; A.L. Burns; S.J. Marx; A.M. Spiegel; J. Shiloach

  Production and purification of human menin from Drosophila melanogaster S2 cells using stirred tank reactor

  Cytotechnology. 2001;35(2):127-135.
  9

• 46.

  2001

  Debra H. Schussheim; Monica C. Skarulis; Sunita K. Agarwal; William F. Simonds; A. Lee Burns; Allen M. Spiegel; Stephen J. Marx

  Multiple endocrine neoplasia type 1: New clinical and basic findings

  Trends in Endocrinology and Metabolism. 2001;12(4):173-178.
  103

• 47.

  2000

  J.I. Knapp; C. Heppner; A.B. Hickman; A.L. Burns; S.C. Chandrasekharappa; F.S. Collins; S.J. Marx; A.M. Spiegel; S.K. Agarwal

  Identification and characterization of JunD missense mutants that lack menin binding

  Oncogene. 2000;19(41):4706-4712.
  16

• 48.

  2000

  Jianxin Hu; Omar Hauache; Allen M. Spiegel

  Human Ca²⁺ receptor cysteine-rich domain: Analysis of function of mutant and chimeric receptors

  Journal of Biological Chemistry. 2000;275(21):16382-16389.
  65

• 49.

  2000

  Larisa V. Debelenko; Jennifer I. Swalwell; Michael J. Kelley; Elisabeth Brambilla; Pachiappan Manickam; Galina Baibakov; Sunita K. Agarwal; Allen M. Spiegel; Stephen J. Marx; Settara C. Chandrasekharappa; et al.

  MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma

  Genes Chromosomes and Cancer. 2000;28(1):58-65.
  30

• 50.

  2000

  Stephan U. Goebel; Christina Heppner; A. Lee Burns; Stephen J. Marx; Allen M. Spiegel; Zhengping Zhuang; Irina A. Lubensky; Fathia Gibril; Robert T. Jensen; et al.

  Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas

  Journal of Clinical Endocrinology and Metabolism. 2000;85(1):116-123.
  68

• 51.

  2000

  O.M. Hauache; J. Hu; K. Ray; R. Xie; K.A. Jacobson; A.M. Spiegel

  Effects of a calcimimetic compound and naturally activating mutations on the human Ca²⁺ receptor and on Ca²⁺ receptor/metabotropic glutamate chimeric receptors

  Endocrinology. 2000;141(11):4156-4163.
  60

• 52.

  2000

  Allen M. Spiegel

  G protein defects in signal transduction

  Hormone Research. 2000;53(SUPPL. 3):17-22.
  25

• 53.

  2000

  O.M. Hauache; J. Hu; K. Ray; A.M. Spiegel

  Functional interactions between the extracellular domain and the seven-transmembrane domain in Ca ²⁺ receptor activation

  Endocrine. 2000;13(1):63-70.
  10

• 54.

  2000

  P. Bianco; M. Riminucci; A. Majolagbe; S.A. Kuznetsov; M.T. Collins; M.H. Mankani; A. Corsi; H.G. Bone; S. Wientroub; A.M. Spiegel; et al.

  Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone

  Journal of Bone and Mineral Research. 2000;15(1):120-128.
  108

• 55.

  2000

  Pachiappan Manickam; Andreas M. Vogel; Sunita K. Agarwal; Takaya Oda; Allen M. Spiegel; Stephen J. Marx; Francis S. Collins; Brant M. Weinstein; Settara C. Chandrasekharappa

  Isolation, characterization, expression and functional analysis of the zebrafish ortholog of MEN1

  Mammalian Genome. 2000;11(6):448-454.
  31

• 56.

  2000

  Stephan U. Goebel; Paolo L. Peghini; Paul K. Goldsmith; Allen M. Spiegel; Fathia Gibril; Mark Raffeld; Robert T. Jensen; Jose Serrano

  Expression of the calcium-sensing receptor in gastrinomas

  Journal of Clinical Endocrinology and Metabolism. 2000;85(11):4131-4137.
  36

• 57.

  1999

  Y.S. Kim; A.L. Burns; P.K. Goldsmith; C. Heppner; S.Y. Park; S.C. Chandrasekharappa; F.S. Collins; A.M. Spiegel; S.J. Marx

  Stable overexpression of MEN1 suppresses tumorigenicity of RAS

  Oncogene. 1999;18(43):5936-5942.
  73

• 58.

  1999

  Kausik Ray; Benjamin C. Hauschild; Peter J. Steinbach; Paul K. Goldsmith; Omar Hauache; Allen M. Spiegel

  Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca²⁺ receptor critical for dimerization. Implications for function of monomeric Ca²⁺ receptor

  Journal of Biological Chemistry. 1999;274(39):27642-27650.
  122

• 59.

  1999

  Alexander O. Vortmeyer; Irina A. Lubensky; Monica Skarulis; Guang Li; Young-Wan Moon; Won-Sang Park; Robert Weil; Carrolee Barlow; Allen M. Spiegel; Stephen J. Marx; et al.

  Multiple endocrine neoplasia type 1: Atypical presentation, clinical course, and genetic analysis of multiple tumors

  Modern Pathology. 1999;12(9):919-924.
  28

• 60.

  1999

  A.M. Spiegel

  Citation for the 1999 Monsanto Clinical Investigator Lecture Award of the Endocrine Society to Dr. Stephen J. Marx.

  Endocrine reviews. 1999;20(4):590-591.
  0

• 61.

  1999

  S.J. Marx; S.K. Agarwal; C. Heppner; Y.S. Kim; M.B. Kester; P.K. Goldsmith; M.C. Skarulis; A.M. Spiegel; A.L. Burns; L.V. Debelenko; et al.

  The gene for multiple endocrine neoplasia type 1: Recent findings

  Bone. 1999;25(1):119-122.
  25

• 62.

  1999

  Paul K. Goldsmith; Gao-Feng Fan; Kausik Ray; Joseph Shiloach; Peter McPhie; Kimberly V. Rogers; Allen M. Spiegel

  Expression, purification, and biochemical characterization of the amino- terminal extracellular domain of the human calcium receptor

  Journal of Biological Chemistry. 1999;274(16):11303-11309.
  47

• 63.

  1999

  Xin-Mei Zhao; Omar Hauache; Paul K. Goldsmith; Regina Collins; Allen M. Spiegel

  A missense mutation in the seventh transmembrane domain constitutively activates the human Ca²⁺ receptor

  FEBS Letters. 1999;448(1):180-184.
  41

• 64.

  1999

  Adam C. Berger; Steven K. Libutti; David L. Bartlett; Monica G. Skarulis; Stephen J. Marx; Allen M. Spiegel; John L. Doppman; H. Richard Alexander

  Heterogeneous gland size in sporadic multiple gland parathyroid hyperplasia

  Journal of the American College of Surgeons. 1999;188(4):382-389.
  12

• 65.

  1999

  Sunita K. Agarwal; Siradanahalli C. Guru; Christina Heppner; Michael R. Erdos; Regina M. Collins; Sylvia Y. Park; Suraj Saggar; Settara C. Chandrasekharappa; Francis S. Collins; Allen M. Spiegel; et al.

  Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

  Cell. 1999;96(1):143-152.
  358

• 66.

  1999

  S.J. Marx; S.K. Agarwal; M.B. Rester; C. Heppner; Y.S. Kim; M.C. Skarulis; L.A. James; P.K. Goldsmith; S.K. Saggar; S.Y. Park; et al.

  Multiple endocrine neoplasia type 1: Clinical and genetic features of the hereditary endocrine neoplasias

  Recent Progress in Hormone Research. 1999;54:397-439.
  99

• 67.

  1999

  Allen M. Spiegel

  Hormone resistance caused by mutations in G proteins and G protein- coupled receptors

  Journal of Pediatric Endocrinology and Metabolism. 1999;12(SUPPL. 1):303-309.
  3

• 68.

  1999

  Mara Riminucci; Bin Liu; Alessandro Corsi; Andrew Shenker; Allen M. Spiegel; Pamela Gehron Robey; Paolo Bianco

  The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gsα gene: Site-specific patterns and recurrent histological hallmarks

  Journal of Pathology. 1999;187(2):249-258.
  87

• 69.

  1999

  Christina Heppner; Martin Reincke; Sunita K. Agarwal; Patricia Mora; Bruno Allolio; A. Lee Burns; Allen M. Spiegel; Stephen J. Marx

  MEN1 gene analysis in sporadic adrenocortical neoplasms

  Journal of Clinical Endocrinology and Metabolism. 1999;84(1):216-219.
  64

• 70.

  1999

  Steven K. Libutti; H. Richard Alexander; David L. Bartlett; Maureen L. Sampson; Mark E. Ruddel; Monica Skarulis; Stephen J. Marx; Allen M. Spiegel; William Simmonds; Alan T. Remaley

  Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism

  Surgery. 1999;126(6):1145-1151.
  94

• 71.

  1999

  Siradanahalli C. Guru; Judy S. Crabtree; Kevin D. Brown; Karen J. Dunn; Pachiappan Manickam; Nijaguna B. Prasad; Danny Wangsa; A. Lee Burns; Allen M. Spiegel; et al.

  Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene

  Mammalian Genome. 1999;10(6):592-596.
  39

• 72.

  1998

  Kausik Ray; Peter Clapp; Paul K. Goldsmith; Allen M. Spiegel

  Identification of the sites of N-linked glycosylation on the human calcium receptor and assessment of their role in cell surface expression and signal transduction

  Journal of Biological Chemistry. 1998;273(51):34558-34567.
  89

• 73.

  1998

  Gao-Feng Fan; Kausik Ray; Xin-Mei Zhao; Paul K. Goldsmith; Allen M. Spiegel

  Mutational analysis of the cysteines in the extracellular domain of the human Ca²⁺ receptor: Effects on cell surface expression, dimerization and signal transduction

  FEBS Letters. 1998;436(3):353-356.
  64

• 74.

  1998

  Stephen Marx; Allen M. Spiegel; Monica C. Skarulis; John L. Doppman; Francis S. Collins; Lance A. Liotta

  Multiple endocrine neoplasia type 1: Clinical and genetic topics

  Annals of Internal Medicine. 1998;129(6):484-494.
  191

• 75.

  1998

  John L. Doppman; Monica C. Skarulis; Richard Chang; H. Richard Alexander; David Bartlett; Steven K. Libutti; Stephen J. Marx; Allen M. Spiegel

  Hypocalcemic stimulation and nonselective venous sampling for localizing parathyroid adenomas: Work in progress

  Radiology. 1998;208(1):145-151.
  9

• 76.

  1998

  Paolo Bianco; Sergei A. Kuznetsov; Mara Riminucci; Larry W. Fisher; Allen M. Spiegel; Pamela Gehron Robey

  Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsα-mutated skeletal progenitor cells

  Journal of Clinical Investigation. 1998;101(8):1737-1744.
  119

• 77.

  1998

  Siradanahalli C. Guru; Paul K. Goldsmith; A. Lee Burns; Stephen J. Marx; Allen M. Spiegel; Francis S. Collins; Settara C. Chandrasekharappa

  Menin, the product of the MEN1 gene, is a nuclear protein

  Proceedings of the National Academy of Sciences of the United States of America. 1998;95(4):1630-1634.
  282

• 78.

  1998

  Michael R. Emmert-Buck; Larisa V. Debelenko; Sunita Agarwal; Mary Beth Kester; Pachiappan Manickam; Zhengping Zhuang; Siradanahalli C. Guru; Shodimu-Emmanuel Olufemi; A. Lee Burns; et al.

  11q13 allelotype analysis in 27 Northern American MEN1 kindreds identifies two distinct founder chromosomes

  Molecular Genetics and Metabolism. 1998;63(2):151-155.
  9

• 79.

  1998

  Michael T. Collins; Monica C. Skarulis; John P. Bilezikian; Shonni J. Silverberg; Allen M. Spiegel; Stephen J. Marx

  Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent

  Journal of Clinical Endocrinology and Metabolism. 1998;83(4):1083-1088.
  127

• 80.

  1998

  Shodimu-Emmanuel Olufemi; Jane S. Green; Pachiappan Manickam; Siradanahalli C. Guru; Sunita K. Agarwal; Mary Beth Kester; Qihan Dong; A. Lee Burns; Allen M. Spiegel; Stephen J. Marx; et al.

  Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1(Burin)) in four kindreds from Newfoundland

  Human Mutation. 1998;11(4):264-269.
  75

• 81.

  1998

  S.C. Guru; P. Manickam; J.S. Crabtree; S.-E. Olufemi; S.K. Agarwal; L.V. Debelenko; Z. Zhuang; I.A. Lubensky; M.B. Kester; Y.S. Kim; et al.

  Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene

  Journal of Internal Medicine. 1998;243(6):433-439.
  19

• 82.

  1998

  Sunita K. Agarwal; Larisa V. Debelenko; Mary Beth Kester; Siradanahalli C. Guru; Pachiappan Manickam; Shodimu-Emmanuel Olufemi; Monica C. Skarulis; Christina Hcppner; Judy S. Crabtree; Irina A. Lubensky; et al.

  Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families

  Human Mutation. 1998;12(2):75-82.
  24

• 83.

  1998

  S.J. Marx; S.K. Agarwal; M.B. Kester; C. Heppner; Y.S. Kim; M.R. Emmert-Buck; L.V. Debelenko; I.A. Lubensky; Z. Zhuang; S.C. Guru; et al.

  Germline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1)

  Journal of Internal Medicine. 1998;243(6):447-453.
  25

• 84.

  1997

  Zhengping Zhuang; Shereen Z. Ezzat; Alexander O. Vortmeyer; Robert Weil; Edward H. Oldfield; Won-Sang Park; Svetlana Pack; Steve Huang; Sunita K. Agarwal; Siradanahalli C. Guru; et al.

  Mutations of the MEN1 tumor suppressor gene in pituitary tumors

  Cancer Research. 1997;57(24):5446-5451.
  175

• 85.

  1997

  Kausik Ray; Gao-Feng Fan; Paul K. Goldsmith; Allen M. Spiegel

  The carboxyl terminus of the human calcium receptor. Requirements for cell-surface expression and signal transduction

  Journal of Biological Chemistry. 1997;272(50):31355-31361.
  87

• 86.

  1997

  Mara Riminucci; Larry W. Fisher; Andrew Shenker; Allen M. Spiegel; Paolo Bianco; Pamela Gehron Robey

  Fibrous dysplasia of bone in the McCune-Albright syndrome: Abnormalities in bone formation

  American Journal of Pathology. 1997;151(6):1587-1600.
  114

• 87.

  1997

  Steven K. Libutti; David L. Bartlett; Nora T. Jaskowiak; Monica Skarulis; Stephen J. Marx; Allen M. Spiegel; Douglas L. Fraker; John L. Doppman; Thomas J. Shawker; et al.

  The role of thyroid resection during reoperation for persistent or recurrent hyperparathyroidism

  Surgery. 1997;122(6):1183-1188.
  9

• 88.

  1997

  Larisa V. Debelenko; Elisabeth Brambilla; Sunita K. Agarwal; Jennifer I. Swalwell; Mary B. Kester; Irina A. Lubensky; Zhengping Zhuang; Siradanahalli C. Guru; Pachiappan Manickam; et al.

  Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung

  Human Molecular Genetics. 1997;6(13):2285-2290.
  157

• 89.

  1997

  Paul K. Goldsmith; Gaofeng Fan; Jeffery L. Miller; Kimberly V. Rogers; Allen M. Spiegel

  Monoclonal antibodies against synthetic peptides corresponding to the extracellular domain of the human Ca²⁺ receptor: Characterization and use in studying concanavalin a inhibition

  Journal of Bone and Mineral Research. 1997;12(11):1780-1788.
  38

• 90.

  1997

  Zhengping Zhuang; Alexander O. Vortmeyer; Svetlana Pack; Steve Huang; Thu A. Pham; Chaoyu Wang; Won-Sang Park; Sunita K. Agarwal; Larisa V. Debelenko; MaryBeth Kester; et al.

  Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas

  Cancer Research. 1997;57(21):4682-4686.
  208

• 91.

  1997

  A.M. Spiegel

  Citation for the 1997 Gerald D. Aurbach Lecture Award of The Endocrine Society to Edward M. Brown.

  Endocrine reviews. 1997;18(4):616-617.
  0

• 92.

  1997

  Siradanahalli C. Guru; Sunita K. Agarwal; Pachiappan Manickam; Shodimu-Emmanuel Olufemi; Judy S. Crabtree; Jane M. Weisemann; Mary Beth Kester; Young S. Kim; Yingping Wang; Michael R. Emmert-Buck; et al.

  A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus

  Genome Research. 1997;7(7):725-735.
  58

• 93.

  1997

  Sunita K. Agarwal; Mary Beth Kester; Larisa V. Debelenko; Christina Heppner; Michael R. Emmert-Buck; Monica C. Skarulis; John L. Doppman; Young S. Kim; Irina A. Lubensky; Zhengping Zhuang; et al.

  Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states

  Human Molecular Genetics. 1997;6(7):1169-1175.
  305

• 94.

  1997

  Siradanahalli C. Guru; Shodimu-Emmanuel Olufemi; Pachiappan Manickam; Christiano Cummings; Linn M. Gieser; Brian L. Pike; Michael L. Bittner; Yuan Jiang; A. Craig Chinault; Norma J. Nowak; et al.

  A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13

  Genomics. 1997;42(3):436-445.
  35

• 95.

  1997

  Larisa V. Debelenko; Zhengping Zhuang; Michael R. Emmert-Buck; Settara C. Chandrasekharappa; Pachiappan Manickam; Siradanahalli C. Guru; Stephen J. Marx; Monica C. Skarulis; Allen M. Spiegel; et al.

  Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumors

  Cancer Research. 1997;57(11):2238-2243.
  119

• 96.

  1997

  Michael R. Emmert-Buck; Irina A. Lubensky; Qihan Dong; Pachiappan Manickam; Siradanahalli C. Guru; Mary Beth Kester; Shodimu-Emmanuel Olufemi; Sunita Agarwal; A. Lee Burns; et al.

  Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis

  Cancer Research. 1997;57(10):1855-1858.
  60

• 97.

  1997

  Settara C. Chandrasekharappa; Siradanahalli C. Guru; Pachiappan Manickam; Shodimu-Emmanuel Olufemi; Francis S. Collins; Michael R. Emmert-Buck; Larisa V. Debelenko; Zhengping Zhuang; Irina A. Lubensky; Lance A. Liotta; et al.

  Positional cloning of the gene for multiple endocrine neoplasia-type 1

  Science. 1997;276(5311):404-406.
  1104

• 98.

  1997

  Allen M. Spiegel

  The molecular basis of disorders caused by defects in G proteins

  Hormone Research. 1997;47(3):89-96.
  56

• 99.

  1997

  G. Fan; P.K. Goldsmith; R. Collins; C.K. Dunn; K.J. Krapcho; K.V. Rogers; A.M. Spiegel

  N-linked glycosylation of the human Ca²⁺ receptor is essential for its expression at the cell surface

  Endocrinology. 1997;138(5):1916-1922.
  58

• 100.

  1997

  Thomas N. Darling; Monica C. Skarulis; Seth M. Steinberg; Stephen J. Marx; Allen M. Spiegel; Maria Turner

  Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1

  Archives of Dermatology. 1997;133(7):853-857.
  159

• 101.

  1997

  C. Heppner; M.B. Kester; S.K. Agarwal; L.V. Debelenko; M.R. Emmert-Buck; S.C. Guru; P. Manickam; S.-E. Olufemi; M.C. Skarulis; J.L. Doppman; et al.

  Somatic mutation of the MEN1 gene in parathyroid tumours

  Nature Genetics. 1997;16(4):375-378.
  289

• 102.

  1997

  Qihan Dong; Larisa V. Debelenko; Settara C. Chandrasekharappa; Michael R. Emmert-Buck; Zhengping Zhuang; Siradanahalli C. Guru; Pachiappan Manickam; Monica Skarulis; Irina A. Lubensky; et al.

  Loss of heterozygosity at 11q13: Analysis of pituitary tumors, lung carcinoids, lipomas, and other uncommon tumors in subjects with familial multiple endocrine neoplasia type 1

  Journal of Clinical Endocrinology and Metabolism. 1997;82(5):1416-1420.
  84

• 103.

  1997

  Maria S. Rodriguez-Pena; Regina Collins; Charles Woodard; Allen M. Spiegel

  Decreased insulin content and secretion in RIN 1046-38 cells overexpressing α ₂-adrenergic receptors

  Endocrine. 1997;7(2):255-260.
  8

• 104.

  1997

  Pachiappan Manickam; Siradanahalli C. Guru; Larisa V. Debelenko; Sunita K. Agarwal; Shodimu-Emmanuel Olufemi; Jane M. Weisemann; Mark S. Boguski; Judy S. Crabtree; Yingping Wang; Bruce A. Roe; et al.

  Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1 (MEN1) region

  Human Genetics. 1997;101(1):102-108.
  48

• 105.

  1997

  Larisa V. Debelenko; Michael R. Emmert-Buck; Pachiappan Manickam; Marybeth Kester; Siradanahalli C. Guru; Estela M. DiFranco; Shodimu-Emmanuel Olufemi; Sunita Agarwal; Irina A. Lubensky; Zhengping Zhuang; et al.

  Haplotype analysis defines a minimal interval for the multiple endocrine neoplasia type 1 (MEN1) gene

  Cancer Research. 1997;57(6):1039-1042.
  37

• 106.

  1997

  Francesco De Luca; Kausik Ray; Edna E. Mancilla; Gao-Feng Fan; Karen K. Winer; Pankaj Gore; Allen M. Spiegel; Jeffrey Baron

  Sporadic hypoparathyroidism caused by de novo gain-of-function mutations of the Ca²⁺-sensing receptor

  Journal of Clinical Endocrinology and Metabolism. 1997;82(8):2710-2715.
  71

• 107.

  1997

  A.M. Spiegel

  Komrower lecture: Inborn errors of signal transduction: Mutations in G proteins and G protein-coupled receptors as a cause of disease

  Journal of Inherited Metabolic Disease. 1997;20(2):113-121.
  30

• 108.

  1996

  David Wenkert; Torsten Schoneberg; John J. Merendino Jr.; Maria Sol Rodriguez Pena; Ruth Vinitsky; Paul K. Goldsmith; Jurgen Wess; Allen M. Spiegel

  Functional characterization of five V2 vasopressin receptor gene mutations

  Molecular and Cellular Endocrinology. 1996;124(1-2):43-50.
  45

• 109.

  1996

  Irina A. Lubensky; Larisa V. Debelenko; Zhengping Zhuang; Michael R. Emmert-Buck; Qihan Dong; Settara Chandrasekharappa; Siradanahalli C. Guru; Pachiappan Manickam; Shodimu-Emmanuel Olufemi; et al.

  Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients

  Cancer Research. 1996;56(22):5272-5278.
  101

• 110.

  1996

  John L. Doppman; Monica C. Skarulis; Clara C. Chen; Richard Chang; Harvey I. Pass; Douglas L. Fraker; H. Richard Alexander; Bruno Niederle; Stephen J. Marx; Jeffrey A. Norton; et al.

  Parathyroid adenomas in the aortopulmonary window

  Radiology. 1996;201(2):456-462.
  26

• 111.

  1996

  Sylvie Hermouet; Sadie Aznavoorian; Allen M. Spiegel

  In vitro and in vivo growth inhibition of murine melanoma K-1735 cells by a dominant negative mutant α subunit of the G_i2 protein

  Cellular Signalling. 1996;8(3):159-166.
  18

• 112.

  1996

  Nora Jaskowiak; Jeffrey A. Norton; H. Richard Alexander; John L. Doppman; Thomas Shawker; Monica Skarulis; Stephen Marx; Allen Spiegel; Douglas L. Fraker

  A prospective trial evaluating a standard approach to reoperation for missed parathyroid adenoma

  Annals of Surgery. 1996;224(3):308-322.
  118

• 113.

  1996

  A.M. Spiegel

  Defects in G protein-coupled signal transduction in human disease

  Annual Review of Physiology. 1996;58:143-170.
  162

• 114.

  1996

  Qihan Dong; Françoise Brucker-Davis; Bruce D. Weintraub; Robert C. Smallridge; Frances E. Carr; James Battey; Allen M. Spiegel; Andrew Shenker

  Screening of Candidate Oncogenes in Human Thyrotroph Tumors: Absence of Activating Mutations of the Gα_q, Gα₁₁, Gα_s, or Thyrotropin-Releasing Hormone Receptor Genes

  Journal of Clinical Endocrinology and Metabolism. 1996;81(3):1134-1140.
  48

• 115.

  1996

  Allen M. Spiegel

  Mutations in G proteins and G protein-coupled receptors in endocrine disease

  Journal of Clinical Endocrinology and Metabolism. 1996;81(7):2434-2442.
  106

• 116.

  1995

  Andrew Shenker; Philippe Chanson; Lee S. Weinstein; Patty Chi; Allen M. Spiegel; Abderrahim Lomri; Pierre J. Marie

  Osteoblastic cells derived from isolated lesions of fibrous dysplasia contain activating somatic mutations of the G_sα gene

  Human Molecular Genetics. 1995;4(9):1675-1676.
  53

• 117.

  1995

  A.M. Spiegel

  G protein gene knockout hits the gut

  Nature Medicine. 1995;1(6):522-524.
  4

• 118.

  1995

  A. Varrault; M.S. Rodriguez Pena; P.K. Goldsmith; A. Mithal; E.M. Brown; A.M. Spiegel

  Expression of G protein α-subunits in bovine parathyroid

  Endocrinology. 1995;136(10):4390-4396.
  31

• 119.

  1995

  J.F. Buell; D.L. Fraker; J.L. Doppman; T.H. Shawker; M.C. Skarulis; A.M. Spiegel; S.J. Marx; H.R. Alexander

  High cervical intravagal hypercellular parathyroid gland as the etiology of severe persistent primary hyperparathyroidism

  American Surgeon. 1995;61(11):943-946.
  7

• 120.

  1995

  Q. Dong; A. Shenker; J. Way; B.R. Haddad; K. Lin; M.R. Hughes; O.W. McBride; A.M. Spiegel; J. Battey

  Molecular cloning of human Gα(q) cDNA and chromosomal localization of the Gα(q) gene (GNAQ) and a processed pseudogene

  Genomics. 1995;30(3):470-475.
  22

• 121.

  1995

  C.C. Chen; M.C. Skarulis; D.L. Fraker; H.R. Alexander; S.J. Marx; A.M. Spiegel

  Technetium-99m-sestamibi imaging before reoperation for primary hyperparathyroidism

  Journal of Nuclear Medicine. 1995;36(12):2186-2191.
  64

• 122.

  1995

  C.C. Chen; A. Premkumar; S.C. Hill; M.C. Skarulis; A.M. Spiegel

  Tc-99m sestamibi imaging of a hyperfunctioning parathyroid autograft with Doppler ultrasound and MRI correlation

  Clinical Nuclear Medicine. 1995;20(3):222-225.
  11

• 123.

  1994

  Michael Y. Degtyarev; Allen M. Spiegel; Teresa L. Z. Jones

  Palmitoylation of a G protein α_i subunit requires membrane localization not myristoylation

  Journal of Biological Chemistry. 1994;269(49):30898-30903.
  72

• 124.

  1994

  Abdul B. Abou-Samra; Paul K. Goldsmith; Lin Y. Xie; Harald Jüppner; Allen M. Spiegel; Gino V. Segre

  Down-regulation of parathyroid (PTH)/PTH-related peptide receptor immunoreactivity and PTH binding in opossum kidney cells by PTH and dexamethasone

  Endocrinology. 1994;135(6):2588-2594.
  24

• 125.

  1994

  David Wenkert; John J. Merendino Jr.; Andrew Shenker; Nina Thambi; Gary L. Robertson; Arnold M. Moses; Allen M. Spiegel

  Novel mutations in the V2 vasopressin receptor gene of patients with X-linked nephrogenic diabetes insipidus

  Human Molecular Genetics. 1994;3(8):1429-1430.
  18

• 126.

  1994

  Vickie J. LaMorte; Jackie Thorburn; Devin Absher; Allen Spiegel; Joan Heller Brown; Kenneth R. Chien; James R. Feramisco; Kirk U. Knowlton

  G_q- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following α₁-Adrenergic stimulation

  Journal of Biological Chemistry. 1994;269(18):13490-13496.
  136

• 127.

  1994

  Michael Y. Degtyarev; Allen M. Spiegel; Teresa L.Z. Jones

  The membrane localization of the G protein α_s subunit is not dependent on its tenir sequence or effector domain

  Cellular Signalling. 1994;6(1):25-33.
  7

• 128.

  1994

  M.P. MacFarlane; D.L. Fraker; T.H. Shawker; J.A. Norton; J.L. Doppman; R.A. Chang; M.C. Skarulis; S.J. Marx; A.M. Spiegel; H.R. Alexander; et al.

  Use of preoperative fine-needle aspiration in patients undergoing reoperation for primary hyperparathyroidism

  Surgery. 1994;116(6):959-965.
  26

• 129.

  1994

  K.G. Billingsley; D.L. Fraker; J.L. Doppman; J.A. Norton; T.H. Shawker; M.C. Skarulis; S.J. Marx; A.M. Spiegel; H.R. Alexander; et al.

  Localization and operative management of undescended parathyroid adenomas in patients with persistent primary hyperparathyroidism

  Surgery. 1994;116(6):982-990.
  35

• 130.

  1994

  A. Shenker; L.S. Weinstein; D.E. Sweet; A.M. Spiegel

  An activating G(s)α mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome

  Journal of Clinical Endocrinology and Metabolism. 1994;79(3):750-755.
  135

• 131.

  1994

  J.L. Doppman; T.H. Shawker; D.L. Fraker; H.R. Alexander; M.C. Skarulis; E.E. Lack; A.M. Spiegel

  Parathyroid adenoma within the vagus nerve

  American Journal of Roentgenology. 1994;163(4):943-945.
  7

• 132.

  1993

  Sonia L. Sugg; Douglas L. Fraker; H.Richard Alexander; John L. Doppman; Donald L. Miller; Richard Chang; Monica C. Skarulis; Stephen J. Marx; Allen M. Spiegel; Jeffrey A. Norton

  Prospective evaluation of selective venous sampling for parathyroid hormone concentration in patients undergoing reoperations for primary hyperparathyroidism

  Surgery. 1993;114(6):1004-1010.
  38

• 133.

  1993

  Michael Y. Degtyarev; Allen M. Spiegel; Teresa L. Z. Jones

  Increased palmitoylation of the G_s protein α subunit after activation by the β-adrenergic receptor or cholera toxin

  Journal of Biological Chemistry. 1993;268(32):23769-23772.
  116

• 134.

  1993

  Andrew Shenker; Lee S. Weinstein; Antoinette Moran; Ora H. Pescovitz; Nancy J. Charest; Charlotte M. Boney; Judson J. Van Wyk; Maria J. Merino; Penelope P. Feuillan; Allen M. Spiegel

  Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein G_s

  The Journal of Pediatrics. 1993;123(4):509-518.
  177

• 135.

  1993

  Sylvie Hermouet; Takeshi Murakami; Allen M. Spiegel

  Stable changes in expression or activation of G protein α_i or α_q subunits affect the expression of both β₁ and β₂ subunits

  FEBS Letters. 1993;327(2):183-188.
  16

• 136.

  1993

  V.J. Lamorte; A.T. Harootunian; A.M. Spiegel; R.Y. Tsien; J.R. Feramisco

  Mediation of growth factor induced DNA synthesis and calcium mobilization by G_q and G_i2

  Journal of Cell Biology. 1993;121(1):91-99.
  69

• 137.

  1993

  T.L.Z. Jones; C. Woodard; A.M. Spiegel

  Baculovirus Expression and Purification of a Soluble, Mutant G-Protein α Subunit

  Protein Expression and Purification. 1993;4(1):64-71.
  6

• 138.

  1993

  Sylvie Hermouet; Philippe De Mazancourt; Allen M. Spiegel

  Mitogenic effects of pertussis toxin-sensitive G-protein α subunits: The mitogenic action of α_i2 in NIH 3T3 cells is mimicked by α_i1, but not α_i3

  Cellular Signalling. 1993;5(2):215-225.
  10

• 139.

  1993

  A.M. Spiegel; L.S. Weinstein; A. Shenker; S. Hermouet; J.J. Merendino Jr.

  G proteins: from basic to clinical studies.

  Advances in second messenger and phosphoprotein research. 1993;28:37-46.
  3

• 140.

  1993

  H.G. Dohlman; P. Goldsmith; A.M. Spiegel; J. Thorner

  Pheromone action regulates G-protein α-subunit myristoylation in the yeast Saccharomyces cerevisiae

  Proceedings of the National Academy of Sciences of the United States of America. 1993;90(20):9688-9692.
  36

• 141.

  1993

  A.M. Spiegel; L.S. Weinstein; A. Shenker

  Abnormalities in G protein-coupled signal transduction pathways in human disease

  Journal of Clinical Investigation. 1993;92(3):1119-1125.
  80

• 142.

  1993

  R. Pamukcu; A.M. Spiegel; E.B. Chang

  Biochemical and immunochemical localization of GTP-binding proteins in the rat ileal enterocyte

  Journal of Laboratory and Clinical Medicine. 1993;121(5):689-696.
  0

• 143.

  1993

  J.J. Merendino Jr.; A.M. Spiegel; J.D. Crawford; A.-M. O'Carroll; M.J. Brownstein; S.J. Lolait

  Brief report: A mutation in the vasopressin V2-receptor gene in a kindred with X-linked nephrogenic diabetes insipidus

  New England Journal of Medicine. 1993;328(21):1538-1541.
  22

• 144.

  1992

  Sylvie Hermouet; Philippe de Mazancourt; Allen M. Spiegel; Marilyn Gist Farquhar; Bridget S. Wilson

  High level expression of transfected G protein α_i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts

  FEBS Letters. 1992;312(2-3):223-228.
  15

• 145.

  1992

  J.T. Potts Jr.; A.M. Spiegel

  In memoriam Gerald D. Aurbach.

  Journal of Clinical Endocrinology and Metabolism. 1992;75(5):1386-1388.
  0

• 146.

  1992

  J.T. Potts Jr.; A.M. Spiegel

  In memoriam Gerald D. Aurbach.

  Molecular endocrinology (Baltimore, Md.). 1992;6(11):1982-1984.
  0

• 147.

  1992

  Lee S. Weinstein; Pablo V. Gejman; Philippe de Mazancourt; Nadine American; Allen M. Spiegel

  A heterozygous 4-bp deletion mutation in the G_sα gene (GNAS1) in a patient with albright hereditary osteodystrophy

  Genomics. 1992;13(4):1319-1321.
  57

• 148.

  1992

  Judy L. Meinkoth; Paul K. Goldsmit; Allen M. Spiegel; James R. Feramisco; Gerard N. Burrow

  Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, G_s

  Journal of Biological Chemistry. 1992;267(19):13239-13245.
  23

• 149.

  1992

  Vickie J. LaMorte; Paul K. Goldsmith; Allen M. Spiegel; Judy L. Meinkoth; James R. Feramisco

  Inhibition of DNA synthesis in living cells by microinjection of Gi₂ antibodies

  Journal of Biological Chemistry. 1992;267(2):691-694.
  30

• 150.

  1992

  E.A. Streeten; L.S. Weinstein; J.A. Norton; J.J. Mulvihill; B.J. White; E. Friedman; G. Jaffe; M.L. Brandi; K. Stewart; M.B. Zimering; et al.

  Studies in a kindred with parathyroid carcinoma

  Journal of Clinical Endocrinology and Metabolism. 1992;75(2):362-366.
  29

• 151.

  1992

  E. Friedman; L. De Marco; P.V. Gejman; J.A. Norton; A.E. Bale; G.D. Aurbach; A.M. Spiegel; S.J. Marx

  Allelic loss from chromosome 11 in parathyroid tumors

  Cancer Research. 1992;52(24):6804-6809.
  75

• 152.

  1992

  A.M. Spiegel; A. Shenker; L.S. Weinstein

  Receptor-effector coupling by G proteins: Implications for normal and abnormal signal transduction

  Endocrine Reviews. 1992;13(3):536-565.
  180

• 153.

  1992

  Y.-S. Juhnn; T.L.Z. Jones; A.M. Spiegel

  Amino- and carboxy-terminal deletion mutants of Gsα are localized to the particulate fraction of transfected COS cells

  Journal of Cell Biology. 1992;119(3):523-529.
  5

• 154.

  1992

  James E. Butrynski; Teresa L.Z. Jones; Peter S. Backlund Jr.; Allen M. Spiegel

  Differential isoprenylation of carboxy-terminal mutants of an inhibitory G-protein α-subunit: Neither farnesylation nor geranylgeranylation is sufficient for membrane attachment

  Biochemistry. 1992;31(34):8030-8035.
  7

• 155.

  1992

  Allen M. Spiegel

  G proteins in cellular control

  Current Opinion in Cell Biology. 1992;4(2):203-211.
  10

• 156.

  1992

  A.M. Spiegel

  Role of G proteins in signal transduction.

  Clinical Neuropharmacology. 1992;15 Suppl 1 Pt A:200A-201A.
  1

• 157.

  1992

  Gerard M. Doherty; John L. Doppman; Donald L. Miller; Mimi S. Gee; Stephen J. Marx; Allen M. Spiegel; Gerald D. Aurbach; Harvey I. Pass; Murray F. Brennan; Jeffrey A. Norton

  Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism

  Annals of Surgery. 1992;215(2):101-106.
  34

• 158.

  1992

  Takeshi Murakami; William F. Simonds; Allen M. Spiegel

  Site-specific antibodies directed against G protein β and γ subunits: Effects on α and βγ subunit interaction

  Biochemistry®. 1992;31(11):2905-2911.
  15

• 159.

  1992

  A.M. Spiegel

  Heterotrimeric GTP-binding proteins: An expanding family of signal transducers

  Medicinal Research Reviews. 1992;12(1):55-71.
  8

• 160.

  1991

  Susan L. Hamilton; Juan Codina; Mary J. Hawkes; Atsuko Yatani; Tadao Sawada; Faith M. Strickland; Stanley C. Froehner; Allen M. Spiegel; Ligia Toro; Enrico Stefani; et al.

  Evidence for direct interaction of G_sα with the Ca²⁺ channel of skeletal muscle

  Journal of Biological Chemistry. 1991;266(29):19528-19535.
  24

• 161.

  1991

  Wolfgang Holter; Allen M. Spiegel; Bruce H. Howard; Sabine Weber; Mark R. Brannt

  Expression of GTP-binding proteins and prostaglandin E₂ receptors during human T cell activation

  Cellular Immunology. 1991;134(2):287-295.
  13

• 162.

  1991

  Annick Fargin; Kiohei Yamamoto; Susanna Cotecchia; Paul K. Goldsmith; Allen M. Spiegel; Eduardo G. Lapetina; Marc G. Caron; Robert J. Lefkowitz

  Dual coupling of the cloned 5-HT_1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same G₁ protein

  Cellular Signalling. 1991;3(6):547-557.
  41

• 163.

  1991

  A. Shenker; P. Goldsmith; C.G. Unson; A.M. Spiegel

  The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family.

  Transactions of the Association of American Physicians. 1991;104:11-20.
  3

• 164.

  1991

  M. Cormont; Y.L. Marchand-Brustel; E. Van Obberghen; A.M. Spiegel; G.W.G. Sharp

  Identification of G protein α-subunits in RINm5F cells and their selective interaction with galanin receptor

  Diabetes. 1991;40(9):1170-1176.
  20

• 165.

  1991

  A.M. Spiegel; P.S. Backlund Jr.; J.E. Butrynski; T.L.Z. Jones; W.F. Simonds

  The G protein connection: Molecular basis of membrane association

  Trends in Biochemical Sciences. 1991;16(9):338-341.
  41

• 166.

  1991

  A.M. Spiegel

  Pathophysiology of primary hyperparathyroidism

  Journal of Bone and Mineral Research. 1991;6(SUPPL. 2):S15-S17.
  8

• 167.

  1991

  W.F. Simonds; J.E. Butrynski; N. Gautam; C.G. Unson; A.M. Spiegel

  G-protein βγ dimers. Membrane targeting requires subunit coexpression and intact γ C-A-A-X domain

  Journal of Biological Chemistry. 1991;266(9):5363-5366.
  98

• 168.

  1991

  S.J. Marx; J. Menczel; G. Campbell; G.D. Aurbach; A.M. Spiegel; J.A. Norton

  Heterogeneous size of the parathyroid glands in familial multiple endocrine neoplasia type 1

  Clinical Endocrinology. 1991;35(6):521-526.
  28

• 169.

  1991

  A.E. Bale; J.A. Norton; E.L. Wong; J.S. Fryburg; P.N. Maton; E.H. Oldfield; E. Streeten; G.D. Aurbach; M.L. Brandi; et al.

  Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine neoplasia type 1

  Cancer Research. 1991;51(4):1154-1157.
  57

• 170.

  1991

  M. Begeot; D. Langlois; A.M. Spiegel; J.M. Saez

  Regulation of guanine nucleotide binding regulatory proteins in cultured adrenal cells by adrenocorticotropin and angiotensin-II

  Endocrinology. 1991;128(6):3162-3168.
  14

• 171.

  1991

  Andrew Shenker; Paul Goldsmith; Cecilia G. Unson; Allen M. Spiegel

  The G protein coupled to the thromboxane A₂ receptor in human platelets is a member of the novel G_q family

  Journal of Biological Chemistry. 1991;266(14):9309-9313.
  186

• 172.

  1991

  Sylvie Hermouet; John J. Merendino Jr.; J. Silvio Gutkind; Allen M. Spiegel

  Activating and inactivating mutations of the α subunit of G_i2 protein have opposite effects on proliferation of NIH 3T3 cells

  Proceedings of the National Academy of Sciences of the United States of America. 1991;88(23):10455-10459.
  66

• 173.

  1991

  D.L. Fraker; W.D. Travis; J.J. Merendino Jr.; M.B. Zimering; E.A. Streeten; L.S. Weinstein; S.J. Marx; A.M. Spiegel; G.D. Aurbach; et al.

  Locally recurrent parathyroid neoplasms as a cause for recurrent and persistent primary hyperparathyroidism

  Annals of Surgery. 1991;213(1):58-65.
  19

• 174.

  1991

  P.V. Gejman; L.S. Weinstein; M. Martinez; A.M. Spiegel; Q. Cao; W.-T. Hsieh; M.R. Hoehe; E.S. Gershon

  Genetic mapping of the Gs-α subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis

  Genomics. 1991;9(4):782-783.
  37

• 175.

  1991

  L.S. Weinstein; A. Shenker; P.V. Gejman; M.J. Merino; E. Friedman; A.M. Spiegel

  Activating mutations of the stimulatory G protein in the McCune-Albright syndrome

  New England Journal of Medicine. 1991;325(24):1688-1695.
  672

• 176.

  1990

  Dermot M.F. Cooper; Christine L. Boyajian; Paul K. Goldsmith; Cecilia G. Unson; Allen Spiegel

  Differential expression of low molecular weight form of G_s-α in neostriatum and cerebellum: correlation with expression of calmodulin-independent adenylyl cyclase

  Brain Research. 1990;523(1):143-146.
  7

• 177.

  1990

  Lee S. Weinstein; Inna Kats; Allen M. Spiegel; Anthony D. Carter

  Characterization of the promoter of the human G_i2 α-subunit gene

  Molecular Endocrinology. 1990;4(7):958-964.
  5

• 178.

  1990

  Susan E. Senogles; Allen M. Spiegel; Elena Padrell; Ravi Iyengar; Marc G. Caron

  Specificity of receptor-G protein interactions: Discrimination of G_i subtypes by the D₂ dopamine receptor in a reconstituted system

  Journal of Biological Chemistry. 1990;265(8):4507-4514.
  71

• 179.

  1990

  A.M. Spiegel

  Albright's hereditary osteodystrophy and defective G proteins

  New England Journal of Medicine. 1990;322(20):1461-1462.
  13

• 180.

  1990

  A.M. Spiegel

  Receptor-effector coupling by G-proteins: Implications for neuronal plasticity

  Progress in Brain Research. 1990;86:269-276.
  1

• 181.

  1990

  Lee S. Weinstein; Pablo V. Gejman; Eitan Friedman; Takashi Kadowaki; Regina M. Collins; Elliot S. Gershon; Allen M. Spiegel

  Mutations of the G_s α-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis

  Proceedings of the National Academy of Sciences of the United States of America. 1990;87(21):8287-8290.
  123

• 182.

  1990

  T.L.Z. Jones; A.M. Spiegel

  Isoprenylation of an inhibitory G protein α subunit occurs only upon mutagenesis of the carboxyl terminus

  Journal of Biological Chemistry. 1990;265(32):19389-19392.
  5

• 183.

  1990

  W.J. Wolfgang; F. Quan; P. Goldsmith; C. Unson; A. Spiegel; M. Forte

  Immunolocalization of G protein α-subunits in the Drosophila CNS

  Journal of Neuroscience. 1990;10(3):1014-1024.
  23

• 184.

  1990

  Diane Morris; Elizabeth McHugh-Sutkowski; Malcolm Moos Jr.; William F. Simonds; Allen M. Spiegel; Kenneth B. Seamon

  Immunoprecipitation of adenylate cyclase with an antibody to a carboxyl-terminal peptide from Gsα

  Biochemistry®. 1990;29(38):9079-9084.
  11

• 185.

  1990

  A.M. Spiegel; W.F. Simonds; T.L.Z. Zones; P.K. Goldsmith; C.G. Unson

  Antibodies as probes of G-protein receptor-effector coupling and of G-protein membrane attachment

  Biochemical Society Symposia. 1990;56:61-69.
  8

• 186.

  1990

  A.M. Spiegel; W.F. Simonds; T.L. Jones; P.K. Goldsmith; C.G. Unson

  Antibodies against synthetic peptides as probes of G protein structure and function.

  Society of General Physiologists series. 1990;45:185-195.
  10

• 187.

  1990

  E. Friedman; A.E. Bale; S.J. Marx; J.A. Norton; A. Arnold; T. Tu; G.D. Aurbach; A.M. Spiegel

  Genetic abnormalities in sporadic parathyroid adenomas

  Journal of Clinical Endocrinology and Metabolism. 1990;71(2):293-297.
  24

• 188.

  1990

  P.S. Backlund Jr.; W.F. Simonds; A.M. Spiegel

  Carboxyl methylation and COOH-terminal processing of the brain G-protein γ-subunit

  Journal of Biological Chemistry. 1990;265(26):15572-15576.
  12

• 189.

  1990

  T.L.Z. Jones; W.F. Simonds; J.J. Merendino Jr.; M.R. Brann; A.M. Spiegel

  Myristoylation of an inhibitory GTP-binding protein α subunit is essential for its membrane attachment

  Proceedings of the National Academy of Sciences of the United States of America. 1990;87(2):568-572.
  78

• 190.

  1990

  D.L. Fraker; J.L. Doppman; T.H. Shawker; S.J. Marx; A.M. Spiegel; J.A. Norton

  Undescended parathyroid adenoma: An important etiology for failed operations for primary hyperparathyroidism

  World Journal of Surgery. 1990;14(3):342-348.
  23

• 191.

  1989

  Murakami Takeshi; Kevin Rossiter; Allen M. Spiegel; Bertram Sacktor

  Identification of multiple G_i subtypes and a novel G protein in bovine kidney cortex

  Biochemical Pharmacology. 1989;38(24):4502-4505.
  2

• 192.

  1989

  William F. Simonds; Paul K. Goldsmith; Charles J. Woodard; Cecilia G. Unson; Allen M. Spiegel

  Receptor and effector interactions of G_s Functional studies with antibodies to the α_s carboxyl-terminal decapeptide

  FEBS Letters. 1989;249(2):189-194.
  68

• 193.

  1989

  S. Daniel-Issakani; A.M. Spiegel; B. Strulovici

  Lipopolysaccharide response is linked to the GTP binding protein, Gi₂, in the promonocytic cell line U937

  Journal of Biological Chemistry. 1989;264(34):20240-20247.
  50

• 194.

  1989

  E. Friedman; K. Sakaguchi; A.E. Bale; A. Falchetti; E. Streeten; M.B. Zimering; L.S. Weinstein; W.O. McBride; Y. Nakamura; et al.

  Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1

  New England Journal of Medicine. 1989;321(4):213-218.
  150

• 195.

  1989

  N.C. Thambi; F. Quan; W.J. Wolfgang; A. Spiegel; M. Forte

  Immunological and molecular characterization of G(oα)-like proteins in the Drosophila central nervous system

  Journal of Biological Chemistry. 1989;264(31):18552-18560.
  22

• 196.

  1989

  B.R. Lester; J.B. McCarthy; Z. Sun; R.S. Smith; L.T. Furcht; A.M. Spiegel

  G-protein involvement in matrix-mediated motility and invasion of high and low experimental metastatic B16 melanoma clones

  Cancer Research. 1989;49(21):5940-5948.
  14

• 197.

  1989

  W.F. Simonds; R.M. Collins; A.M. Spiegel; M.R. Brann

  Membrane attachment of recombinant G-protein α-subunits in excess of βγ subunits in a eukaryotic expression system

  Biochemical and Biophysical Research Communications. 1989;164(1):46-53.
  7

• 198.

  1989

  W.F. Simonds; P.K. Goldsmith; J. Codina; C.G. Unson; A.M. Spiegel

  G(i2) mediates α₂-adrenergic inhibition of adenylyl cyclase in platelet membranes: In situ identification with G(α) C-terminal antibodies

  Proceedings of the National Academy of Sciences of the United States of America. 1989;86(20):7809-7813.
  120

• 199.

  1989

  R. Sagi-Eisenberg; L.M. Traub; A.M. Spiegel; Y. Zick

  Protein kinase C-mediated phosphorylation of retinal rod outer segment membrane proteins

  Cellular Signalling. 1989;1(5):519-531.
  14

• 200.

  1989

  J.P. Longabaugh; J. Didsbury; A. Spiegel; G.L. Stiles

  Modification of the rat adipocyte A₁ adenosine receptor-adenylate cyclase system during chronic exposure to an A₁ adenosine receptor agonist: Alterations in the quantity of G(Sα) and G(iα) are not associated with changes in their mRNAs

  Molecular Pharmacology. 1989;36(5):681-688.
  62

• 201.

  1989

  G.G. Holz IV; R.M. Kream; A. Spiegel; K. Dunlap

  G proteins couple α-adrenergic and GABA(b) receptors to inhibition of peptide secretion from peripheral sensory neurons

  Journal of Neuroscience. 1989;9(2):657-666.
  44

• 202.

  1988

  L.S. Weinstein; A.M. Spiegel; A.D. Carter

  Cloning and characterization of the human gene for the α-subunit of G_i2, a GTP-binding signal transduction protein

  FEBS Letters. 1988;232(2):333-340.
  14

• 203.

  1988

  P. Goldsmith; K. Rossiter; A. Carter; W. Simonds; C.G. Unson; R. Vinitsky; A.M. Spiegel

  Identification of the GTP-binding protein encoded by Gi3 complementary DNA.

  Journal of Biological Chemistry. 1988;263(14):6476-6479.
  32

• 204.

  1988

  F.R. McKenzie; E.C. Kelly; C.G. Unson; A.M. Spiegel; G. Milligan

  Antibodies which recognize the C-terminus of the inhibitory guanine-nucleotide-binding protein (Gi) demonstrate that opioid peptides and foetal-calf serum stimulate the high-affinity GTPase activity of two separate pertussis-toxin substrates.

  Biochemical Journal. 1988;249(3):653-659.
  7

• 205.

  1988

  A. Spiegel; A. Carter; M. Brann; R. Collins; P. Goldsmith; W. Simonds; R. Vinitsky; B. Eide; K. Rossiter; et al.

  Signal transduction by guanine nucleotide-binding proteins.

  Recent progress in hormone research. 1988;44:337-375.
  2

• 206.

  1988

  A.M. Spiegel

  Guanine nucleotide binding proteins and signal transduction.

  Vitamins and Hormones. 1988;44:47-101.
  2

• 207.

  1988

  R. Cortes; T. Hokfelt; M. Schalling; M. Goldstein; P. Goldsmith; A. Spiegel; C. Unson; J. Walsh

  Antiserum raised against residues 159-168 of the guanine nucleotide-binding protein G(i3)-α reacts with ependymal cells and some neurons in the rat brain containing cholecystokinin- or cholecystokinin- and tyrosine 3-hydroxylase-like immunoreactivities

  Proceedings of the National Academy of Sciences of the United States of America. 1988;85(23):9351-9355.
  5

• 208.

  1988

  G.E. Darling; S.J. Marx; A.M. Spiegel; G.D. Aurbach; J.A. Norton; O. Clark; I.B. Rosen; R.C. Merrell; M.F. Brennan; J.P. Delaney

  Prospective analysis of intraoperative and postoperative urinary cyclic adenosine 3',5'-monophosphate levels to predict outcome of patients undergoing reoperations for primary hyperparathyroidism

  Surgery. 1988;104(6):1128-1136.
  6

• 209.

  1988

  Peter S. Backlund Jr.; Robert R. Aksamit; Cecilia G. Unson; Paul Goldsmith; Allen M. Spiegel; Graeme Milligan

  Immunochemical and electrophoretic characterization of the major pertussis toxin substrate of the RAW264 macrophage cell line

  Biochemistry. 1988;27(6):2040-2046.
  7

• 210.

  1988

  A.M. Spiegel

  G proteins in clinical medicine

  Hospital Practice. 1988;23(6):93-112.
  2

• 211.

  1988

  R.A. Cerione; S. Kroll; R. Rajaram; C. Unson; P. Goldsmith; A.M. Spiegel

  An antibody directed against the carboxyl-terminal decapeptide of the α subunit of the retinal GTP-binding protein, transducin. Effects on transducin function

  Journal of Biological Chemistry. 1988;263(19):9345-9352.
  11

• 212.

  1988

  T. Zaremba; P. Gierschik; M. Pines; P. Bray; A. Carter; R. Kahn; C. Simons; R. Vinitsky; P. Goldsmith; A. Spiegel

  Immunochemical studies of the 36-kDa common β subunit of guanine nucleotide-binding proteins: Identification of a major epitope

  Molecular Pharmacology. 1988;33(3):257-264.
  0

• 213.

  1988

  S.Y. Schmidt; C.A. Heth; R.B. Edwards; J.T. Brandt; A.J. Adler; A. Spiegel; H. Shichi; E.L. Berson

  Identification of proteins in retinas and IPM from eyes with retinitis pigmentosa

  Investigative Ophthalmology and Visual Science. 1988;29(11):1585-1593.
  4

• 214.

  1988

  F.R. McKenzie; I. Mullaney; C.G. Unson; A.M. Spiegel; G. Milligan

  The use of anti-peptide antisera to probe interactions between receptors and guanine nucleotide binding proteins

  Biochemical Society Transactions. 1988;16(4):434-437.
  7

• 215.

  1988

  Paul Goldsmith; Peter S. Backlund Jr.; Kevin Rossiter; Anthony Carter; Graeme Milligan; Cecilia G. Unson; Allen Spiegel

  Purification of heterotrimeric GTP-binding proteins from brain: Identification of a novel form of G_o

  Biochemistry. 1988;27(18):7085-7090.
  21

• 216.

  1988

  G. Milligan; I. Mullaney; C.G. Unson; L. Marshall; A.M. Spiegel; H. McArdle

  GTP analogues promote release of the α subunit of the guanine nucleotide binding protein, G(i)2, from membranes of rat glioma C6 BU1 cells

  Biochemical Journal. 1988;254(2):391-396.
  5

• 217.

  1988

  D. Rotrosen; J.I. Gallin; A.M. Spiegel; H.L. Malech

  Subcellular localization of G(iα) in human neutrophils

  Journal of Biological Chemistry. 1988;263(22):10958-10964.
  11

• 218.

  1988

  R. Collu; C. Bouvier; G. Lagace; C.G. Unson; G. Milligan; P. Goldsmith; A.M. Spiegel

  Selective deficiency of guanine nucleotide-binding protein G(o) in two dopamine-resistant pituitary tumors

  Endocrinology. 1988;122(3):1176-1178.
  11

• 219.

  1987

  Brock Eide; Peter Gierschik; Graeme Milligan; Ian Mullaney; Cecilia Unson; Paul Goldsmith; Allen Spiegel

  GTP-Binding proteins in brain and neutrophil are tethered to the plasma membrane via their amino termini

  Biochemical and Biophysical Research Communications. 1987;148(3):1398-1405.
  6

• 220.

  1987

  P. Goldsmith; P. Gierschik; G. Milligan; C.G. Unson; R. Vinitsky; H.L. Malech; A.M. Spiegel

  Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain.

  Journal of Biological Chemistry. 1987;262(30):14683-14688.
  96

• 221.

  1987

  A. Carter; C. Bardin; R. Collins; C. Simons; P. Bray; A. Spiegel

  Reduced expression of multiple forms of the alpha subunit of the stimulatory GTP-binding protein in pseudohypoparathyroidism type Ia.

  Proceedings of the National Academy of Sciences of the United States of America. 1987;84(20):7266-7269.
  20

• 222.

  1987

  Kenneth A. Kern; Thomas H. Shawker; John L. Doppman; Donald L. Miller; Stephen J. Marx; Allen M. Spiegel; Gerald D. Aurbach; Jeffrey A. Norton

  The use of high-resolution ultrasound to locate parathyroid tumors during reoperations for primary hyperparathyroidism

  World Journal of Surgery. 1987;11(5):579-585.
  13

• 223.

  1987

  Mark R. Brann; Regina M. Collins; Allen Spiegel

  Localization of mRNAs encoding the α-subunits of signal-transducing G-proteins within rat brain and among peripheral tissues

  FEBS Letters. 1987;222(1):191-198.
  24

• 224.

  1987

  Philip M. Murphy; Brock Eide; Paul Goldsmith; Mark Brann; Peter Gierschik; Allen Spiegel; Harry L. Malech

  Detection of multiple forms of G_iα in HL60 cells

  FEBS Letters. 1987;221(1):81-86.
  13

• 225.

  1987

  Y. Zick; A.M. Spiegel; R. Sagi-Eisenberg

  Insulin-like growth factor I receptors in retinal rod outer segments.

  Journal of Biological Chemistry. 1987;262(21):10259-10264.
  13

• 226.

  1987

  D. Gawler; G. Milligan; A.M. Spiegel

  Abolition of the expression of inhibitory guanine nucleotide regulatory protein G(i) activity in diabetes

  Nature. 1987;326(6119):229-232.
  63

• 227.

  1987

  D.L. Miller; J.L. Doppman; R. Chang; S.J. Thayer; T.J. O'Leary; J.A. Norton; A.M. Spiegel; S.J. Marx; G.D. Aurbach

  Angiographic ablation of parathyroid adenomas: Lessons from a 10-year experience

  Radiology. 1987;165(3):601-607.
  20

• 228.

  1987

  G. Milligan; P. Gierschik; A.M. Spiegel

  The use of specific antibodies to identify and quantify guanine nucleotide-binding proteins

  Biochemical Society Transactions. 1987;15(1):42-45.
  2

• 229.

  1987

  D.L. Miller; J.L. Doppman; A.G. Krudy; T.H. Shawker; J.A. Norton; J.J. Vucich; K.A. Morrish; S.J. Marx; A.M. Spiegel; G.D. Aurbach

  Localization of parathyroid adenomas in patients who have undergone surgery. Part II. Invasive procedures

  Radiology. 1987;162(1):138-141.
  17

• 230.

  1987

  D.L. Miller; J.L. Doppman; T.H. Shawker; A.G. Krudy; J.A. Norton; J.J. Vucich; K.A. Morrish; S.J. Marx; A.M. Spiegel; G.D. Aurbach

  Localization of parathyroid adenomas in patients who have undergone surgery. Part I. Noninvasive imaging methods

  Radiology. 1987;162(1):133-137.
  51

• 231.

  1987

  Richard A. Cerione; Peter Gierschik; Claudia Staniszewski; Jeffrey L. Benovic; Juan Codina; Robert Somers; Lutz Birnbaumer; Allen M. Spiegel; Robert J. Lefkowitz; Marc G. Caron

  Functional differences in the βγ complexes of transducin and the inhibitory guanine nucleotide regulatory protein

  Biochemistry. 1987;26(5):1485-1491.
  5

• 232.

  1987

  S.E. Senogles; J.L. Benovic; N. Amlaiky; C. Unson; G. Milligan; R. Vinitsky; A.M. Spiegel; M.G. Caron

  The D ₂-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein

  Journal of Biological Chemistry. 1987;262(10):4860-4867.
  33

• 233.

  1987

  R.P. Lad; C. Simons; P. Gierschik; G. Milligan; C. Woodard; M. Griffo; P. Goldsmith; R. Ornberg; C.R. Gerfen; et al.

  Differential distribution of signal-transducing G-proteins in retina

  Brain Research. 1987;423(1-2):237-246.
  3

• 234.

  1987

  G. Milligan; R.A. Streaty; P. Gierschik; A.M. Spiegel; W.A. Klee

  Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain

  Journal of Biological Chemistry. 1987;262(18):8626-8630.
  21

• 235.

  1987

  G. Milligan; A.M. Spiegel; C.G. Unson; E.D. Saggerson

  Chemically induced hypothyroidism produces elevated amounts of the α subunit of the inhibitory guanine nucleotide binding protein (G(i)) and the β subunit common to all G-proteins

  Biochemical Journal. 1987;247(1):223-227.
  10

• 236.

  1987

  Charles W Luetje; Peter Gierscik; Graeme Milligan; Cecilia Unson; Allen Spiegel; Neil M. Nathanson

  Tissue-specific regulation of GTP-binding protein and muscarinic acetylcholine receptor levels during cardiac development

  Biochemistry®. 1987;26(15):4876-4884.
  12

• 237.

  1987

  A.M. Spiegel

  Signal transduction by guanine nucleotide binding proteins

  Molecular and Cellular Endocrinology. 1987;49(1):1-16.
  32

• 238.

  1987

  P. Bray; A. Carter; V. Guo; C. Puckett; J. Kamholz; A. Spiegel; M. Nirenberg

  Human cDNA clones for an α subunit of G(i) signal-transduction protein

  Proceedings of the National Academy of Sciences of the United States of America. 1987;84(15):5115-5119.
  7

• 239.

  1987

  P. Gierschik; D. Sidiropoulos; A. Spiegel; K.H. Jakobs

  Purification and immunochemical characterization of the major pertussis-toxin-sensitive guanine-nucleotide-binding protein of bovine-neutrophil membranes

  European Journal of Biochemistry. 1987;165(1):185-194.
  4

• 240.

  1986

  Judith Falloon; Harry Malech; Graeme Milligan; Cecilia Unson; Richard Kahn; Paul Goldsmith; Allen Spiegel

  Detection of the major pertussis toxin substrate of human leukocytes with antisera raised against synthetic peptides

  FEBS Letters. 1986;209(2):352-356.
  2

• 241.

  1986

  Jeffrey A. Norton; Thomas H. Shawker; Bonnie L. Jones; Allen M. Spiegel; Stephen J. Marx; Lorraine Fitzpatrick; Gerald D. Aurbach; John L. Doppman

  Intraoperative ultrasound and reoperative parathyroid surgery: An initial evaluation

  World Journal of Surgery. 1986;10(4):631-638.
  10

• 242.

  1986

  Peter Gierschik; Bernice Morrow; Graeme Milligan; Charles Rubin; Allen Spiegel

  Changes in the guanine nucleotide-binding proteins, G_i and g_o, during differentiation of 3T3-L1 cells

  FEBS Letters. 1986;199(1):103-106.
  4

• 243.

  1986

  Graeme Milligan; Peter Gierschik; Allen M. Spiegel; Werner A. Klee

  The GTP-binding regulatory proteins of neuroblastoma × glioma, NG108-15, and glioma, C6, cells. Immunochemical evidence of a pertussis toxin substrate that is neither N_i nor N_o

  FEBS Letters. 1986;195(1-2):225-230.
  0

• 244.

  1986

  P. Bray; A. Carter; C. Simons; V. Guo; C. Puckett; J. Kamholz; A. Spiegel; M. Nirenberg

  Human cDNA clones for four species of G(α(s)) signal transduction protein

  Proceedings of the National Academy of Sciences of the United States of America. 1986;83(23):8893-8897.
  106

• 245.

  1986

  B. Eide; P. Gierschik; A. Spiegel

  Immunochemical detection of guanine nucleotide binding proteins mono-ADP-ribosylated by bacterial toxins

  Biochemistry. 1986;25(21):6711-6715.
  4

• 246.

  1986

  R.A. Cerione; C. Staniszewski; P. Gierschik; J. Codina; R.L. Somers; L. Birnbaumer; A.M. Spiegel; M.G. Caron; R.J. Lefkowitz

  Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system

  Journal of Biological Chemistry. 1986;261(20):9514-9520.
  7

• 247.

  1986

  R.A. Cerione; J.W. Regan; H. Nakata; J. Codina; J.L. Benovic; P. Gierschik; R.L. Somers; A.M. Spiegel; L. Birnbaumer; R.J. Lefkowitz

  Functional reconstitution of the α₂-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles

  Journal of Biological Chemistry. 1986;261(8):3901-3909.
  23

• 248.

  1986

  M. Pines; A. Santora; A. Spiegel

  Effects of phorbol esters and pertussis toxin on agonist-stimulated cyclic AMP production in rat osteosarcoma cells

  Biochemical Pharmacology. 1986;35(20):3639-3641.
  2

• 249.

  1986

  P. Gierschik; J. Falloon; C. Milligan; M. Pines; J.I. Gallin; A. Spiegel

  Immunochemical evidence for a novel pertussis toxin substrate in human neutrophils

  Journal of Biological Chemistry. 1986;261(17):8058-8062.
  3

• 250.

  1986

  W.E. Heydorn; P. Gierschik; G.J. Creed; G. Milligan; A. Spiegel; D.M. Jacobowitz

  The β subunit of the guanine nucleotide regulatory proteins: Identification of its location on two-dimensional gels of brain tissue and its regional and subcellular distribution in brain

  Journal of Neuroscience Research. 1986;16(3):541-552.
  0

• 251.

  1986

  T. van Veen; T. Ostholm; P. Gierschik; A. Spiegel; R. Somers; H.W. Korf; D.C. Klein

  α-Transducin immunoreactivity in retinae and sensory pineal organs of adult vertebrates

  Proceedings of the National Academy of Sciences of the United States of America. 1986;83(4):912-916.
  28

• 252.

  1986

  M.L. Brandi; G.D. Aurbach; L.A. Fitzpatrick; R. Quarto; A.M. Spiegel; M.M. Bliziotes; J.A. Norton; J.L. Doppman; S.J. Marx

  Parathyroid mitogenic activity in plasma from patients with familial multiple endocrine neoplasia type 1

  New England Journal of Medicine. 1986;314(20):1287-1293.
  44

• 253.

  1986

  P. Gierschik; G. Milligan; M. Pines; P. Goldsmith; J. Codina; W. Klee; A. Spiegel

  Use of specific antibodies to quantitate the guanine nucleotide-binding protein G(o) in brain

  Proceedings of the National Academy of Sciences of the United States of America. 1986;83(7):2258-2262.
  26

• 254.

  1986

  R.S. Weinstock; H.N. Wright; A.M. Spiegel; M.A. Levine; A.M. Moses

  Olfactory dysfunction in humans with deficient guanine nucleotide-binding protein

  Nature. 1986;322(6080):635-636.
  16

• 255.

  1986

  M.A. Levine; T.-S. Jap; R.S. Mauseth; R.W. Downs; A.M. Spiegel

  Activity of the stimulatory guanine nucleotide-binding protein is reduced in erythrocytes from patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism: Biochemical, endocrine, and genetic analysis of Albright's hereditary osteodystrophy in six kindreds

  Journal of Clinical Endocrinology and Metabolism. 1986;62(3):497-502.
  65

• 256.

  1986

  G.B. Grunwald; P. Gierschik; M. Nirenberg; A. Spiegel

  Detection of α-transducin in retinal rods but not cones

  Science. 1986;231(4740):856-859.
  3

• 257.

  1986

  C. Silve; A. Santora; N. Breslau; A. Moses; A. Spiegel

  Selective resistance to parathyroid hormone in cultured skin fibroblasts from patients with pseudohypoparathyroidism type Ib

  Journal of Clinical Endocrinology and Metabolism. 1986;62(4):640-644.
  24

• 258.

  1986

  Y. Zick; R. Sagi-Eisenberg; M. Pines; P. Gierschik; A.M. Spiegel

  Multisite phosphorylation of the α subunit of transducin by the insulin receptor kinase and protein kinase C

  Proceedings of the National Academy of Sciences of the United States of America. 1986;83(24):9294-9297.
  27

• 259.

  1986

  M. Pines; A. Santora; P. Gierschik; J. Menczel; A. Spiegel

  The inhibitory guanine nucleotide regulatory protein modulates agonist-stimulated cAMP production in rat osteosarcoma cells

  Bone and Mineral. 1986;1(1):15-26.
  5

• 260.

  1985

  D.R. Dufour; S.J. Marx; A.M. Spiegel

  Parathyroid gland morphology in nonparathyroid hormone-mediated hypercalcemia

  American Journal of Surgical Pathology. 1985;9(1):43-51.
  0

• 261.

  1985

  R.A. Cerione; C. Staniszewski; J.L. Benovic; R.J. Lefkowitz; M.G. Caron; P. Gierschik; R. Somers; A.M. Spiegel; J. Codina; L. Birnbaumer

  Specificity of the functional interactions of the β-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles

  Journal of Biological Chemistry. 1985;260(3):1493-1500.
  40

• 262.

  1985

  A.M. Spiegel; P. Gierschik; M.A. Levine; R.W. Downs Jr.

  Clinical implications of guanine nucleotide-binding proteins as receptor-effector couplers

  New England Journal of Medicine. 1985;312(1):26-33.
  3

• 263.

  1985

  Richard A. Cerione; Juan Codina; Brian F. Kilpatrick; Claudia Staniszewski; Peter Gierschik; Robert L. Somers; Allen M. Spiegel; Lutz Birnbaumer; Marc G. Caron; Robert J. Lefkowitz

  Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems

  Biochemistry. 1985;24(17):4499-4503.
  3

• 264.

  1985

  J. Caselitz; H.E. Stegner; A. Spiegel

  Stromal reaction in breast cancer

  Verhandlungen der Deutschen Gesellschaft fur Pathologie. 1985;69:254-257.
  0

• 265.

  1985

  P. Gierschik; A.M. Spiegel

  Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase

  Archives of Biochemistry and Biophysics. 1985;242(2):457-463.
  0

• 266.

  1985

  J.L. Doppman; T.H. Shawker; A.G. Krudy; D.L. Miller; S.J. Marx; A.M. Spiegel; J.A. Norton; M.F. Brennan; M. Schaaf; G.D. Aurbach

  Parathymic parathyroid: CT, US, and angiographic findings

  Radiology. 1985;157(2):419-423.
  4

• 267.

  1985

  J.M. Skibber; J.C. Reynolds; A.M. Spiegel; S.J. Marx; L.A. Fitzpatrick; G.D. Aurbach; R.A. Wesley; J.A. Norton

  Computerized technetium/thallium scans and parathyroid reoperation

  Surgery. 1985;98(6):1077-1082.
  2

• 268.

  1985

  A.W. Saxe; A. Santora; J. Norton; T. Triche; M.F. Brennan; A. Spiegel

  Morphologic and functional studies of a rat hypercalcemia-associated testicular tumor maintained in cell culture

  Surgery. 1985;98(6):1013-1023.
  0

• 269.

  1985

  C. Silve; A. Santora; A. Spiegel

  A factor produced by cultured rat Leydig tumor (Rice-500) cells associated with humoral hypercalcemia stimulates adenosine 3',5'-monophosphate production via the parathyroid hormone receptor in human skin fibroblasts

  Journal of Clinical Endocrinology and Metabolism. 1985;60(6):1144-1147.
  3

• 270.

  1985

  M. Pines; P. Gierschik; A. Spiegel

  The tryptic and chymotryptic fragments of the β-subunit of guanine nucleotide binding proteins in brain are identical to those of retinal transducin

  FEBS Letters. 1985;182(2):355-359.
  0

• 271.

  1985

  R.W. Downs; R.D. Sekura; M.A. Levine; A.M. Spiegel

  The inhibitory adenylate cyclase coupling protein in pseudohypoparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1985;61(2):351-354.
  3

• 272.

  1985

  M. Pines; P. Gierschik; G. Milligan; W. Klee; A. Spiegel

  Antibodies against the carboxyl-terminal 5-kDa peptide of the α subunit of transducin crossreact with the 40-kDa but not the 39-kDa guanine nucleotide binding protein from brain

  Proceedings of the National Academy of Sciences of the United States of America. 1985;82(12):4095-4099.
  8

• 273.

  1985

  P. Gierschik; J. Codina; C. Simons; L. Birnbaumer; A. Spiegel

  Antisera against a guanine nucleotide binding protein from retina cross-react with the β subunit of the adenyl cyclase-associated guanine nucleotide binding proteins, N(s) and N(i)

  Proceedings of the National Academy of Sciences of the United States of America. 1985;82(3):727-731.
  12

• 274.

  1984

  Peter Gierschik; Cyrena Simons; Charles Woodard; Robert Somers; Allen Spiegel

  Antibodies against a retinal guanine nucleotide-binding protein cross-react with a single plasma membrane protein in non-retinal tissues

  FEBS Letters. 1984;172(2):321-325.
  8

• 275.

  1984

  A.M. Spiegel; M.V. Rudorfer; S.J. Marx; M. Linnoila

  The effect of short term lithium administration on suppressibility of parathyroid hormone secretion by calcium in vivo

  Journal of Clinical Endocrinology and Metabolism. 1984;59(2):354-357.
  11

• 276.

  1984

  A.G. Krudy; J.L. Doppman; S.J. Marx; J.A. Norton; A.M. Spiegel; A.C. Santora II; G.D. Aurbach

  Parathyroid aspiration directed by angiography: An alternative to venous sampling

  Radiology. 1984;152(1):207-208.
  1

• 277.

  1984

  Adrian G. Krudy; Thomas H. Shawker; John L. Doppman; Klara Horvath; Philip D. Schneider; Jeffrey A. Norton; Stephen J. Marx; Allen M. Spiegel

  Ultrasonic parathyroid localisation in previously operated patients

  Clinical Radiology. 1984;35(2):113-118.
  2

• 278.

  1984

  J.A. Heinsimer; A.O. Davies; R.W. Downs; M.A. Levine; A.M. Spiegel; M.K. Drezner; A. De Lean; K.A. Wreggett; M.G. Caron; R.J. Lefkowitz

  Impaired formation of β-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism

  Journal of Clinical Investigation. 1984;73(5):1335-1343.
  2

• 279.

  1984

  A.G. Krudy; J.L. Doppman; D.L. Miller; J.A. Norton; S.J. Marx; A.M. Spiegel; A.C. Santora II; G.D. Aurbach; M. Schaaf

  Detection of mediastinal parathyroid glands by nonselective digital arteriography

  American Journal of Roentgenology. 1984;142(4):693-695.
  1

• 280.

  1984

  C.S. Tam; J.N.M. Heersche; A. Santora; A.M. Spiegel

  Skeletal response in rats following the implantation of hypercalcemia-producing Leydig cell tumors

  Metabolism: Clinical and Experimental. 1984;33(1):50-53.
  2

• 281.

  1984

  A.G. Krudy; J.L. Doppman; T.H. Shawker; A.M. Spiegel; S.J. Marx; J. Norton; M. Schaaf; M.L. Moss; M.A. Weiss; S.H. Schachner

  Hyperfunctioning cystic parathyroid glands: CT and sonographic findings

  American Journal of Roentgenology. 1984;142(1):175-178.
  16

• 282.

  1983

  A.G. Krudy; J.L. Doppman; D.L. Miller; S.J. Marx; J.A. Norton; A.C. Santora II; R.D. Lasker; R.W. Downs; A.M. Spiegel; G.D. Aurbach

  Work in progress: Abnormal parathyroid glands

  Radiology. 1983;148(1):23-29.
  0

• 283.

  1983

  M.F. Attie; J.R. Gill Jr.; J.L. Stock; A.M. Spiegel; R.W. Downs Jr.; M.A. Levine; S.J. Marx

  Urinary calcium excretion in familial hypocalciuric hypercalcemia persistence of relative hypocalciuria after induction of hypoparathyroidism

  Journal of Clinical Investigation. 1983;72(2):667-676.
  82

• 284.

  1983

  J.L. Doppman; A.G. Krudy; S.J. Marx; A. Saxe; P. Schneider; J.A. Norton; A.M. Spiegel; R.W. Downs; M. Schaaf; M.E. Brennan; et al.

  Aspiration of enlarged parathyroid glands for parathyroid hormone assay

  Radiology. 1983;148(1):31-35.
  29

• 285.

  1983

  M.A. Levine; C. Eil; R.W. Downs Jr.; A.M. Spiegel

  Deficient guanine nucleotide regulatory unit activity in cultured fibroblast membranes from patients with pseudohypoparathyroidism type I. A cause of impaired synthesis of 3',5'-cyclic AMP by intact and broken cells

  Journal of Clinical Investigation. 1983;72(1):316-324.
  27

• 286.

  1983

  A.M. Spiegel; A.W. Saxe; L.J. Deftos; M.F. Brennan

  Humoral hypercalcemia caused by a rat Leydig-cell tumor is associated with suppressed parathyroid hormone secretion and increased urinary cAMP excretion

  Hormone and Metabolic Research. 1983;15(6):299-304.
  3

• 287.

  1983

  A.M. Spiegel; R.W. Downs Jr.; A. Santora; S.J. Marx; J. Doppman; J. Shull

  Persistent hyperparathyroidism caused by incomplete parathyroid resection and a hyperfunctioning parathyroid autograft

  Journal of the American Medical Association. 1983;250(14):1896-1898.
  3

• 288.

  1983

  A.M. Spiegel; S.J. Marx; G.D. Aurbach; M.A. Levine

  The phosphaturic response to parathyroid hormone

  New England Journal of Medicine. 1983;308(2):104.
  0

• 289.

  1983

  M.A. Levine; R.W. Downs Jr.; A.M. Moses; N.A. Breslau; S.J. Marx; R.D. Lasker; R.E. Rizzoli; G.D. Aurbach; A.M. Spiegel

  Resistance to multiple hormones in patients with pseudohypoparathyroidism. Association with deficient activity of guanine nucleotide regulatory protein

  American Journal of Medicine. 1983;74(4):545-556.
  101

• 290.

  1983

  R.W. Downs Jr.; M.A. Levine; M.K. Drezner; W.M. Burch Jr.; A.M. Spiegel

  Deficient adenylate cyclase regulatory protein in renal membranes from a patient with pseudohypoparathyroidism

  Journal of Clinical Investigation. 1983;71(2):231-235.
  11

• 291.

  1983

  A.M. Spiegel; S.J. Marx

  Parathyroid hormone and vitamin D receptors

  Clinics in Endocrinology and Metabolism. 1983;12(1):221-241.
  2

• 292.

  1982

  R.D. Lasker; A.M. Spiegel

  Endogenous substrates for cAMP-dependent phosphorylation in dispersed bovine parathyroid cells.

  Endocrinology. 1982;111(4):1412-1414.
  0

• 293.

  1982

  A.M. Spiegel; M.A. Levine; G.D. Aurbach; R.W. Downs Jr.; S.J. Marx; R.D. Lasker; A.M. Moses; N.A. Breslau

  Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism.

  The American journal of physiology. 1982;243(1):E37-42.
  1

• 294.

  1982

  S.J. Marx; A.M. Spiegel; M.A. Levine; R.E. Rizzoli; R.D. Lasker; A.C. Santora; R.W. Downs Jr.; G.D. Aurbach

  Familial hypocalciuric hypercalcemia. The relation to primary parathyroid hyperplasia

  New England Journal of Medicine. 1982;307(7):416-426.
  28

• 295.

  1982

  A.M. Spiegel; M.A. Levine

  Pseudohypoparathyroidism: deficiency of hormone receptor-adenylate cyclase coupling protein as a cause of hereditary hormone resistance.

  Progress in clinical and biological research. 1982;97:327-340.
  1

• 296.

  1982

  A.M. Spiegel; M.A. Levine; S.J. Marx; G.D. Aurbach

  Pseudohypoparathyroidism: The molecular basis for hormone resistance: A retrospective

  New England Journal of Medicine. 1982;307(11):679-681.
  2

• 297.

  1982

  J.L. Stock; B.D. Weintraub; S.W. Rosen; G.D. Aurbach; A.M. Spiegel; S.J. Marx

  Human chorionic gonadotropin subunit measurement in primary hyperparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1982;54(1):57-63.
  11

• 298.

  1982

  W. Krawietz; R.W. Downs Jr.; A.M. Spiegel; G.D. Aurbach

  Vanadate stimulates adenylate cyclase via the guanine nucleotide regulatory protein by a mechanism differing from that of fluoride

  Biochemical Pharmacology. 1982;31(5):843-848.
  6

• 299.

  1982

  Murray F. Brennan; John L. Doppman; Adrian G. Kurdy; Stephen J. Marx; Allen M. Spiegel; Gerald D. Aurbach

  Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism

  Surgery. 1982;91(1):6-11.
  9

• 300.

  1982

  A.G. Krudy; J.L. Doppman; S.J. Marx; M.F. Brennan; A. Spiegel; G.D. Aurback

  Radiographic findings in recurrent parathyroid carcinoma

  Radiology. 1982;142(3):625-629.
  3

• 301.

  1982

  S.J. Marx; M.F. Attie; A.M. Spiegel; M.A. Levine; R.D. Lasker; M. Fox

  An association between neonatal severe primary hyperparathyroidism and familial hypocalciuric hypercalcemia in three kindreds

  New England Journal of Medicine. 1982;306(5):257-264.
  65

• 302.

  1982

  A.W. Saxe; A.M. Spiegel; S.J. Marx; M.F. Brenman

  Deferred parathyroid autografts with cryopreserved tissue after reoperative parathyroid surgery

  Archives of Surgery. 1982;117(5):538-543.
  15

• 303.

  1981

  A.M. Spiegel; R.W. Downs Jr.

  Guanine nucleotides: key regulators of hormone receptor-adenylate cyclase interaction.

  Endocrine Reviews. 1981;2(3):275-305.
  1

• 304.

  1981

  J.L. Stock; A.G. Krudy; J.L. Doppman; A.E. Jones; M.F. Brennan; M.F. Attie; R.W. Downs Jr.; M.A. Levine; S.J. Marx; A.M. Spiegel; et al.

  Parathyroid imaging after intraarterial injections of [ ⁷⁵Se]selenomethionine

  Journal of Clinical Endocrinology and Metabolism. 1981;52(5):835-839.
  1

• 305.

  1981

  S.J. Marx; M.F. Attie; J.L. Stock; A.M. Spiegel; M.A. Levine

  Maximal urine-concentrating ability: Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1981;52(4):736-740.
  55

• 306.

  1981

  A.M. Spiegel; S.J. Marx; M.F. Brennan; E.M. Brown; R.W. Downs Jr.; D.G. Gardner; M.F. Attie; G.D. Aurbach

  Parathyroid function after parathyroidectomy: Evaluation by measurement of urinary cAMP

  Clinical Endocrinology. 1981;15(1):65-73.
  0

• 307.

  1981

  A.G. Krudy; J.L. Doppman; S.J. Marx; A.M. Spiegel; G. Aurbach; M.F. Brennan

  Failure of ablation of a mediastinal parathyroid adenoma by repeated contrast staining

  Radiology. 1981;140(1):63-65.
  3

• 308.

  1981

  M.F. Brennan; S.J. Marx; J. Doppman; J. Costa; A. Saxe; A. Spiegel; A. Krudy; G. Aurbach

  Results of reoperation for persistent and recurrent hyperparathyroidism

  Annals of Surgery. 1981;194(6):671-676.
  22

• 309.

  1981

  S.J. Marx; M.F. Attie; M.A. Levine; A.M. Spiegel; R.W. Downs Jr.; R.D. Lasker

  The hypocalciuric or benign variant of familial hypercalcemia: Clinical and biochemical features in fifteen kindreds

  Medicine. 1981;60(6):397-412.
  150

• 310.

  1981

  R.W. Downs Jr.; S.A. Reen; M.A. Levine; G.D. Aurbach; A.M. Spiegel

  Cholera-toxin-dependent ADP-ribosylation of the adenylate cyclase regulatory protein in Turkey erythrocyte membranes

  Archives of Biochemistry and Biophysics. 1981;209(1):284-290.
  0

• 311.

  1981

  A.M. Spiegel; R.W. Downs Jr.; M.A. Levine; M.J. Singer Jr.; W. Krawietz; S.J. Marx; C.J. Woodard; S.A. Reen; G.D. Aurbach

  The role of guanine nucleotides in regulation of adenylate cyclase activity.

  Recent Progress in Hormone Research. 1981;37:635-665.
  0

• 312.

  1981

  A.G. Krudy; J.L. Doppman; M.F. Brennan; S.J. Marx; A.M. Spiegel; J.L. Stock; G.D. Aurbach

  The detection of mediastinal parathyroid glands by computed tomography, selective arteriography, and venous sampling. An analysis of 17 cases

  Radiology. 1981;140(3):739-744.
  5

• 313.

  1980

  A.M. Spiegel; S.T. Eastman; M.F. Attie; R.W. Downs Jr.; M.A. Levine; S.J. Marx; J.L. Stock; A.W. Saxe; M.F. Brennan; et al.

  Intraoperative measurements of urinary cyclic AMP to guide surgery for primary hyperparathyroidism.

  New England Journal of Medicine. 1980;303(25):1457-1460.
  6

• 314.

  1980

  S.J. Marx; G.D. Aurbach; A.M. Spiegel

  Incidence of primary hyperparathyroidism.

  New England Journal of Medicine. 1980;302(23):1313.
  0

• 315.

  1980

  M.A. Levine; R.W. Downs Jr.; M. Singer; S.J. Marx; G.D. Aurbach; A.M. Spiegel

  Deficient activity of guanine nucleotide regulatory protein in erythrocytes from patients with pseudohypoparathyroidism

  Biochemical and Biophysical Research Communications. 1980;94(4):1319-1324.
  72

• 316.

  1980

  R.W. Downs Jr.; A.M. Spiegel; M. Singer; S. Reen; G.D. Aurbach

  Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein

  Journal of Biological Chemistry. 1980;255(3):949-954.
  5

• 317.

  1980

  S.J. Marx; J.L. Stock; M.F. Attie; R.W. Downs Jr.; D.G. Gardner; E.M. Brown; A.M. Spiegel; J.L. Doppman; M.F. Brennan

  Familial hypocalciuric hypercalcemia: Recognition among patients referred after unsuccessful parathyroid exploration

  Annals of Internal Medicine. 1980;92(3):351-356.
  34

• 318.

  1980

  S.J. Marx; A.M. Spiegel; E.M. Brown; R.W. Downs Jr.; M.F. Attie; J.L. Stock; M.A. Levine; G.D. Aurbach

  Urinary cyclic 3',5'-adenosine monophosphate (cAMP): an index of the action of parathyroid hormone on the kidney.

  Progress in biochemical pharmacology. 1980;17:182-189.
  0

• 319.

  1980

  S.J. Marx; A.M. Spiegel; M.E. Sharp; E.M. Brown; D.G. Gardner; R.W. Downs Jr.; M.F. Attie; J.L. Stock

  Adenosine 3',5'-monophosphate response to parathyroid hormone: Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1980;50(3):546-549.
  1

• 320.

  1980

  M.F. Attie; E.M. Brown; D.G. Gardner; A.M. Spiegel; G.D. Aurbach

  Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion

  Endocrinology. 1980;107(6):1776-1781.
  2

• 321.

  1980

  T.B. Nielsen; R.W. Downs Jr.; A.M. Spiegel

  Restoration of guanine nucleotide- and fluoride-stimulated activity to an adenylate cyclase-deficient cell line with affinity-purified guanine nucleotide regulatory protein

  Biochemical Journal. 1980;190(2):439-443.
  0

• 322.

  1979

  J.L. Doppman; E.M. Brown; M.F. Brennan; A. Spiegel; S.J. Marx; G.D. Aurbach

  Angiographic ablation of parathyroid adenomas

  Radiology. 1979;130(3):577-582.
  12

• 323.

  1979

  E.M. Brown; M.F. Brennan; A.R. Broadus; S.J. Marx; D.G. Gardner; A.M. Spiegel; R.W. Downs Jr.; M.F. Attie; G.D. Aurbach

  Human parathyroid autografts: Comparison of function in vivo and vitro

  Journal of Clinical Endocrinology and Metabolism. 1979;48(4):648-654.
  0

• 324.

  1979

  A.M. Spiegel; R.W. Downs Jr.; G.D. Aurbach

  Separation of a guanine nucleotide regulatory unit from the adenylate cyclase complex with GTP affinity chromatography.

  Journal of cyclic nucleotide research. 1979;5(1):3-17.
  0

• 325.

  1979

  J.L. Doppman; S. Marx; A. Spiegel; E. Brown; R. Downs; M.F. Brennan; G. Aurbach

  Differential diagnosis of brown tumor vs. cystic osteitis by arteriography and computed tomography

  Radiology. 1979;131(2):339-340.
  10

• 326.

  1979

  M.F. Brennan; E.M. Brown; A.M. Spiegel; S.J. Marx; J.L. Doppman; D.C. Jones; G.D. Aurbach

  Autotransplantation of cryopreserved parathyroid tissue in man

  Annals of Surgery. 1979;189(2):139-142.
  8

• 327.

  1979

  E.M. Brown; A.E. Broadus; M.F. Brennan; D.G. Gardner; S.J. Marx; A.M. Spiegel; R.W. Downs Jr.; M. Attie; G.D. Aurbach

  Direct comparison in vivo and in vitro of suppressibility of parathyroid function by calcium in primary hyperparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1979;48(4):604-610.
  20

• 328.

  1979

  D.M. McCarthy; S.R. Peikin; R.N. Lopatin; B.W. Long; A. Spiegel; S. Marx; M. Brennan

  Hyperparathyroidism: a reversible cause of cimetidine-resistant gastric hypersecretion

  British Medical Journal. 1979;1(6180):1765-1766.
  8

• 329.

  1979

  E.M. Brown; D.G. Gardner; M.F. Brennan; S.J. Marx; A.M. Spiegel; M.F. Attie; R.W. Downs Jr.; J.L. Doppman; C.D. Aurbach

  Calcium-regulated parathyroid hormone release in primary hyperparathyroidism. Studies in vitro with dispersed parathyroid cells

  American Journal of Medicine. 1979;66(6):923-931.
  46

• 330.

  1978

  S.J. Marx; A.M. Spiegel; E.M. Brown; J.O. Koehler; D.G. Gardner; M.F. Brennan; G.D. Aurbach

  Divalent cation metabolism. Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism

  The American Journal of Medicine. 1978;65(2):235-242.
  38

• 331.

  1978

  A. Spiegel; M. Greene; I. Magrath; J. Balow; S. Marx; G.D. Aurbach

  Hypercalcemia with suppressed parathyroid hormone in Burkitt's lymphoma

  The American Journal of Medicine. 1978;64(4):691-695.
  2

• 332.

  1978

  A.M. Spiegel; R. Lopatin; S. Peikin; D. McCarthy

  Serum prolactin in patients receiving chronic oral cimetidine

  Lancet. 1978;1(8069):881.
  2

• 333.

  1978

  A.M. Spiegel; S.W. Rosen; B.D. Weintraub; S.P. Marynick

  Effect of intravenous pyridoxine on plasma prolactin in hyperprolactinemic subjects

  Journal of Clinical Endocrinology and Metabolism. 1978;46(4):686-688.
  0

• 334.

  1978

  E.M. Brown; M.F. Brennan; S. Hurwitz; R. Windeck; S.J. Marx; A.M. Spiegel; J.O. Koehler; D.G. Gardner; G.D. Aurbach

  Dispersed cells prepared from human parathyroid glands: distinct calcium sensitivity of adenomas vs. primary hyperplasia

  Journal of Clinical Endocrinology and Metabolism. 1978;46(2):267-276.
  22

• 335.

  1978

  M.F. Brennan; E.M. Brown; S.J. Marx; A.M. Spiegel; A.E. Broadus; J.L. Doppman; B. Webber; G.D. Aurbach

  Recurrent hyperparathyroidism from an autotransplanted parathyroid adenoma

  New England Journal of Medicine. 1978;299(19):1057-1059.
  4

• 336.

  1978

  A.M. Spiegel; S.J. Marx; M.F. Brennan; E.M. Brown; J.O. Koehler; G.D. Aurbach

  Urinary cAMP excretion during surgery. An index of successful parathyroidectomy in patients with primary hyperparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1978;47(3):537-542.
  4

• 337.

  1978

  M.F. Brennan; J.L. Doppman; S.J. Marx; A.M. Spiegel; E.M. Brown; G.D. Aurbach

  Reoperative parathyroid surgery for persistent hyperparathyroidism

  Surgery. 1978;83(6):669-676.
  14

• 338.

  1978

  E. Hewlett; A. Spiegel; J. Wolff; G. Aurbach; C.R. Manclark

  Bordetella pertussis does not induce β-adrenergic blockade

  Infection and Immunity. 1978;22(2):430-434.
  0

• 339.

  1978

  S.J. Marx; A.M. Spiegel; E.M. Brown; D.G. Gardner; R.W. Downs Jr.; M. Attie; A.J. Hamstra; H.F. DeLuca

  A familial syndrome of decrease in sensitivity to 1,25-dihydroxyvitamin D

  Journal of Clinical Endocrinology and Metabolism. 1978;47(6):1303-1310.
  22

• 340.

  1978

  A.M. Spiegel; J.L. Doppman; S.J. Marx; M.F. Brennan; E.M. Brown; R.W. Downs Jr.; D.G. Gardner; M. Attie; G.D. Aurbach

  Preoperative localization of abnormal parathyroid: Neck massage versus arteriography and selective venous sampling

  Annals of Internal Medicine. 1978;89(6):935-936.
  0

• 341.

  1978

  S.J. Marx; A.M. Spiegel; E.M. Brown; R. Windeck; D.G. Gardner; R.W. Downs Jr.; M. Attie; G.D. Aurbach

  Circulating parathyroid hormone activity: Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism

  Journal of Clinical Endocrinology and Metabolism. 1978;47(6):1190-1197.
  4

• 342.

  1977

  R.H. Gerner; R.M. Post; A.M. Spiegel; D.L. Murphy

  Effects of parathormone and lithium treatment on calcium and mood in depressed patients

  Biological Psychiatry. 1977;12(1):145-151.
  2

• 343.

  1977

  A.M. Spiegel; H.E. Harrison; S.J. Marx; E.M. Brown; G.D. Aurbach

  Neonatal primary hyperparathyroidism with autosomal dominant inheritance

  Journal of Pediatrics. 1977;90(2):269-272.
  17

• 344.

  1977

  S.J. Marx; A.M. Spiegel; E.M. Brown; G.D. Aurbach

  Family studies in patients with primary parathyroid hyperplasia

  American Journal of Medicine. 1977;62(5):698-706.
  22

• 345.

  1977

  J.P. Bilezikian; A.M. Spiegel; E.M. Brown; G.D. Aurbach

  Identification and persistence of beta adrenergic receptors during maturation of the rat reticulocyte

  Molecular Pharmacology. 1977;13(5):775-785.
  0

• 346.

  1977

  J.P. Bilezikian; A.M. Spiegel; D.E. Gammon; G.D. Aurbach

  The role of guanyl nucleotides in the expression of catecholamine responsive adenylate cyclase during maturation of the rat reticulocyte

  Molecular Pharmacology. 1977;13(5):786-795.
  0

• 347.

  1977

  C.R. Kollarits; M.L. Moss; D.G. Cogan; J.L. Doppman; G. Di Chiro; G.B. Cutler; S.J. Marx; A.M. Spiegel

  Scleral calcifications in hyperparathyroidism demonstration by computed tomography

  Journal of Computer Assisted Tomography. 1977;1(4):500-504.
  2

• 348.

  1977

  A.M. Spiegel; R.W. Downs Jr.; G.D. Aurbach

  Guanosine 5',α β methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: evidence against pyrophosphorylation mechanism

  Biochemical and Biophysical Research Communications. 1977;76(3):758-764.
  0

• 349.

  1976

  A.M. Spiegel; G. Di Chiro; P. Gorden; A.K. Ommaya; J. Kolins; T.C. Pomeroy

  Diagnosis of radiosensitive hypothalamic tumors without craniotomy. Endocrine and neuroradiologic studies of intracranial atypical teratomas

  Annals of Internal Medicine. 1976;85(3):290-293.
  5

• 350.

  1976

  J.D. Gardner; G.D. Aurbach; A.M. Spiegel; E.M. Brown

  Receptor function and ion transport in turkey erythrocytes.

  Recent Progress in Hormone Research. 1976;32:567-595.
  2

• 351.

  1976

  A.M. Spiegel; E.M. Brown; S.A. Fedak; C.J. Woodard; G.D. Aurbach

  Holocatalytic state of adenylate cyclase in turkey erythrocyte membranes: formation with guanylylimidodiphosphate plus isoproterenol without effect on affinity of β receptor

  Journal of Cyclic Nucleotide Research. 1976;2(1):47-56.
  0

• 352.

  1976

  A.M. Spiegel; E.M. Brown; G.D. Aurbach

  Inhibition of adenylate cyclase by arsenite and cadmium: evidence for a vicinal dithiol requirement

  Journal of Cyclic Nucleotide Research. 1976;2(6):393-404.
  3

• 353.

  1976

  A.M. Spiegel; R.H. Gerner; D.L. Murphy; G.D. Aurbach

  Lithium does not inhibit the parathyroid hormone mediated rise in urinary cyclic AMP and phosphate in humans

  Journal of Clinical Endocrinology and Metabolism. 1976;43(6):1390-1393.
  3

• 354.

  1975

  A.M. Spiegel; S.J. Marx; J.L. Doppman; R.M. Beazley; A.S. Ketcham; B. Kasten; G.D. Aurbach

  Intrathyroidal parathyroid adenoma or hyperplasia. An occasionally overlooked cause of surgical failure in primary hyperparathyroidism.

  Journal of the American Medical Association. 1975;234(10):1029-1033.
  9

• 355.

  1975

  J.L. Doppman; L.E. Mallette; S.J. Marx; J.M. Monchik; A. Broadus; A.M. Spiegel; R. Beazley; G.D. Aurbach

  The localization of abnormal mediastinal parathyroid glands

  Radiology. 1975;115(1):31-36.
  2

• 356.

  1975

  J.L. Doppman; S.J. Marx; A.M. Spiegel; L.E. Mallette; D.R. Wolfe; G.D. Aurbach; G. Geelhoed

  Treatment of hyperparathyroidism by percutaneous embolization of a mediastinal adenoma

  Radiology. 1975;115(1):37-42.
  5

• 357.

  1975

  G.D. Aurbach; A.M. Spiegel; J.D. Gardner

  Beta-adrenergic receptors, cyclic AMP, and ion transport in the avian erythrocyte.

  Advances in cyclic nucleotide research. 1975;5:117-132.
  6

• 358.

  1974

  A.M. Spiegel; G.D. Aurbach

  Binding of 5' guanylyl imidodiphosphate to turkey erythrocyte membranes and effects on β adrenergic activated adenylate cyclase

  Journal of Biological Chemistry. 1974;249(23):7630-7636.
  0

• 359.

  1974

  S.J. Marx; J.L. Doppman; A.M. Spiegel; D. Wolfe; G.D. Aurbach

  Embolization of a mediastinal parathyroid adenoma

  Journal of Clinical Endocrinology and Metabolism. 1974;39(6):1110-11114.
  1

• 360.

  1969

  A.M. Spiegel; M.W. Bitensky

  Effects of chemical and enzymatic modifications of glucagon on its activation of hepatic adenyl cyclase.

  Endocrinology. 1969;85(4):638-643.
  0