Ales Cvekl

Ophthalmology & Visual Sciences

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Ales Cvekl

• Departments
  Ophthalmology & Visual Sciences
  
  

718-430-3217

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Shuying He; Ales Cvekl

  Focus on Molecules: Brg1: A range of functions during eye development

  Experimental Eye Research. 2012;103:117-118.
  0

• 2.

  2012

  Lisa Ann Brennan; Wanda Lee Kantorow; Daniel Chauss; Rebecca Mcgreal; Shuying He; Lyndzie Mattucci; Jianning Wei; S. Amer Riazuddin; Ales Cvekl; J. Fielding Hejtmancik; et al.

  Spatial expression patterns of autophagy genes in the eye lens and induction of autophagy in lens cells

  Molecular Vision. 2012;18:1773-1786.
  0

• 3.

  2011

  Qing Xie; Ales Cvekl

  The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops

  Journal of Biological Chemistry. 2011;286(50):43259-43271.
  4

• 4.

  2010

  Jie Zhou; Yang Liu; Wei Zhang; Vladimir M. Popov; Min Wang; Nagarajan Pattabiraman; Carlos Suñé; Ales Cvekl; Kongming Wu; Jie Jiang; et al.

  Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog

  Journal of Biological Chemistry. 2010;285(51):40342-40350.
  3

• 5.

  2010

  Dorothy A. Frenz; Wei Liu; Ales Cvekl; Qing Xie; Lesley Wassef; Loredana Quadro; Karen Niederreither; Mark Maconochie; Alan Shanske

  Retinoid signaling in inner ear development: A "Goldilocks" phenomenon

  American Journal of Medical Genetics, Part A. 2010;152 A(12):2947-2961.
  8

• 6.

  2010

  Jovica Ninkovic; Luisa Pinto; Stefania Petricca; Alexandra Lepier; Jian Sun; Michael A. Rieger; Timm Schroeder; Ales Cvekl; Jack Favor; Magdalena Götz

  The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA

  Neuron. 2010;68(4):682-694.
  18

• 7.

  2010

  Chunbo Yang; Ying Yang; Lisa Brennan; Eric E. Bouhassira; Marc Kantorow; Ales Cvekl

  Efficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions

  FASEB Journal. 2010;24(9):3274-3283.
  10

• 8.

  2010

  Wei-Lin Wang; Qingtian Li; Jianming Xu; Aleš Cvekl

  Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of Ncoa6 and result in p53-dependent and p53-independent apoptosis

  Molecular Biology of the Cell. 2010;21(14):2453-2468.
  6

• 9.

  2010

  A. Cvekl; K.P. Mitton

  Epigenetic regulatory mechanisms in vertebrate eye development and disease

  Heredity. 2010;105(1):135-151.
  19

• 10.

  2010

  Andrea Caceres; Fu Shang; Eric Wawrousek; Qing Liu; Orna Avidan; Ales Cvekl; Ying Yang; Aydin Haririnia; Andrew Storaska; David Fushman; et al.

  Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in Vivo

  PLoS ONE. 2010;5(10).
  4

• 11.

  2009

  Ales Cvekl; Wei-Lin Wang

  Retinoic acid signaling in mammalian eye development

  Experimental Eye Research. 2009;89(3):280-291.
  18

• 12.

  2009

  Louise V. Wolf; Ying Yang; Jinhua Wang; Qing Xie; Barbara Braunger; Ernst R. Tamm; Jiri Zavadil; Ales Cvekl

  Identification of Pax6-dependent gene regulatory networks in the mouse lens

  PLoS ONE. 2009;4(1).
  30

• 13.

  2008

  Yu Chen; Yong-Qiu Doughman; Shi Gu; Andrew Jarrell; Shin-Ichi Aota; Ales Cvekl; Michiko Watanabe; Sally L. Dunwoodie; Randall S. Johnson; Veronica van Heyningen; et al.

  Cited2 is required for the proper formation of the hyaloid vasculature and for lens morphogenesis

  Development. 2008;135(17):2939-2948.
  10

• 14.

  2008

  Giuseppe F. Pontoriero; Paula Deschamps; Ruth Ashery-Padan; Ryan Wong; Ying Yang; Jiri Zavadil; Ales Cvekl; Shelley Sullivan; Trevor Williams; Judith A. West-Mays

  Cell autonomous roles for AP-2α in lens vesicle separation and maintenance of the lens epithelial cell phenotype

  Developmental Dynamics. 2008;237(3):602-617.
  17

• 15.

  2008

  Louise Wolf; Ying Yang; Eric Wawrousek; Ales Cvekl

  Transcriptional regulation of mouse alpha A-crystallin gene in a 148kb Cryaa BAC and its derivates

  BMC Developmental Biology. 2008;8.
  2

• 16.

  2008

  Varda Oron-Karni; Chen Farhy; Michael Elgart; Till Marquardt; Lena Remizova; Orly Yaron; Qing Xie; Ales Cvekl; Ruth Ashery-Padan

  Dual requirement for Pax6 in retinal progenitor cells

  Development. 2008;135(24):4037-4047.
  25

• 17.

  2007

  Ales Cvekl; Melinda K. Duncan

  Genetic and epigenetic mechanisms of gene regulation during lens development

  Progress in Retinal and Eye Research. 2007;26(6):555-597.
  46

• 18.

  2007

  Ying Yang; Louise V. Wolf; Ales Cvekl

  Distinct Embryonic Expression and Localization of CBP and p300 Histone Acetyltransferases at the Mouse αA-Crystallin Locus in Lens

  Journal of Molecular Biology. 2007;369(4):917-926.
  9

• 19.

  2007

  Kongming Wu; Manran Liu; Anping Li; Howard Donninger; Mahadev Rao; Xuanmao Jiao; Michael P. Lisanti; Ales Cvekl; Michael Birrer; Richard G. Pestell

  Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth

  Molecular Biology of the Cell. 2007;18(3):755-767.
  19

• 20.

  2007

  Melinda K. Pirity; Wei-Lin Wang; Louise V. Wolf; Ernst R. Tamm; Nicole Schreiber-Agus; Ales Cvekl

  Rybp, a polycomb complex-associated protein, is required for mouse eye development

  BMC Developmental Biology. 2007;7.
  6

• 21.

  2006

  Kongming Wu; Anping Li; Mahadev Rao; Manran Liu; Vernon Dailey; Ying Yang; Dolores Di Vizio; Chenguang Wang; Michael P. Lisanti; Guido Sauter; et al.

  DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth

  Molecular and Cellular Biology. 2006;26(19):7116-7129.
  27

• 22.

  2006

  Ying Yang; Tomáš Stopka; Nady Golestaneh; Yan Wang; Kongming Wu; Anping Li; Bharesh K. Chauhan; Chun Y. Gao; Květa Cveklová; Melinda K. Duncan; et al.

  Regulation of αA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin

  EMBO Journal. 2006;25(10):2107-2118.
  43

• 23.

  2005

  Ying Yang; Ales Cvekl

  Tissue-specific regulation of the mouse αA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter

  Journal of Molecular Biology. 2005;351(3):453-469.
  22

• 24.

  2005

  Meryl Castellini; Louise V. Wolf; Bharesh K. Chauhan; Deni S. Galileo; Manfred W. Kilimann; Ales Cvekl; Melinda K. Duncan

  Palm is expressed in both developing and adult mouse lens and retina

  BMC Ophthalmology. 2005;5.
  5

• 25.

  2005

  Andreas Ohlmann; Michael Scholz; Andreas Goldwich; Bharesh K. Chauhan; Kristiane Hudl; Anne V. Ohlmann; Eberhart Zrenner; Wolfgang Berger; Aleš Cvekl; Mathias W. Seeliger; et al.

  Ectopic Norrin induces growth of ocular capillaries and restores normal retinal angiogenesis in Norrie disease mutant mice

  Journal of Neuroscience. 2005;25(7):1701-1710.
  34

• 26.

  2004

  Ying Yang; Bharesh K. Chauhan; Kveta Cveklova; Ales Cvekl

  Transcriptional regulation of mouse αB- and γF-crystallin genes in lens: Opposite promoter-specific interactions between Pax6 and large Maf transcription factors

  Journal of Molecular Biology. 2004;344(2):351-368.
  30

• 27.

  2004

  Ales Cvekl Jr.; Jiri Zavadil; Barbara K. Birshtein; Michael A. Grotzer; Ales Cvekl

  Analysis of transcripts from 17p13.3 in medulloblastoma suggests ROX/MNT as a potential tumour suppressor gene

  European Journal of Cancer. 2004;40(16):2525-2532.
  17

• 28.

  2004

  Karine Zaniolo; Steeve Leclerc; Ales Cvekl; Luc Vallières; Richard Bazin; Kathy Larouche; Sylvain L. Guérin

  Expression of the α4 integrin subunit gene promoter is modulated by the transcription factor Pax-6 in corneal epithelial cells

  Investigative Ophthalmology and Visual Science. 2004;45(6):1692-1704.
  21

• 29.

  2004

  Aleš Cvekl; Ernst R. Tamm

  Anterior eye development and ocular mesenchyme: New insights from mouse models and human diseases

  BioEssays. 2004;26(4):374-386.
  98

• 30.

  2004

  Bharesh K. Chauhan; Ying Yang; Květa Cveklová; Aleš Cvekl

  Functional Properties of Natural Human PAX6 and PAX6(5a) Mutants

  Investigative Ophthalmology and Visual Science. 2004;45(2):385-392.
  22

• 31.

  2004

  Bharesh K. Chauhan; Ying Yang; Květa Cveklová; Aleš Cvekl

  Functional interactions between alternatively spliced forms of Pax6 in crystallin gene regulation and in haploinsufficiency

  Nucleic Acids Research. 2004;32(5):1696-1709.
  28

• 32.

  2004

  Ales Cvekl; Ying Yang; Bharesh K. Chauhan; Kveta Cveklova

  Regulation of gene expression by Pax6 in ocular cells: A case of tissue-preferred expression of crystallins in lens

  International Journal of Developmental Biology. 2004;48(8-9):829-844.
  44

• 33.

  2003

  Kongming Wu; Ying Yang; Chenguang Wang; Maria A. Davoli; Mark D'Amico; Anping Li; Kveta Cveklova; Zbynek Kozmik; Michael P. Lisanti; Robert G. Russell; et al.

  DACH1 Inhibits Transforming Growth Factor-β Signaling through Binding Smad4

  Journal of Biological Chemistry. 2003;278(51):51673-51684.
  54

• 34.

  2003

  Sumanta Goswami; Nancy L. Sheets; Jiři Zavadil; Bharesh K. Chauhan; Erwin P. Bottinger; Venkat N. Reddy; Marc Kantorow; Aleš Cvekl

  Spectrum and range of oxidative stress responses of human lens epithelial cells to H₂O₂ insult

  Investigative Ophthalmology and Visual Science. 2003;44(5):2084-2093.
  51

• 35.

  2002

  Bharesh K. Chauhan; Nathan A. Reed; Ying Yang; Lukáš Čermák; Lixing Reneker; Melinda K. Duncan; Aleš Cvekl

  A comparative cDNA microarray analysis reveals a spectrum of genes regulated by Pax6 in mouse lens

  Genes to Cells. 2002;7(12):1267-1283.
  39

• 36.

  2002

  Daniela C Baulmann; Andreas Ohlmann; Cassandra Flügel-Koch; Sumanta Goswami; Ales Cvekl; Ernst R Tamm

  Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities

  Mechanisms of Development. 2002;118(1-2):3-17.
  70

• 37.

  2002

  Bharesh K. Chauhan; Nathan A. Reed; Weijia Zhang; Melinda K. Duncan; Manfred W. Kilimann; Aleš Cvekl

  Identification of genes downstream of Pax6 in the mouse lens using cDNA microarrays

  Journal of Biological Chemistry. 2002;277(13):11539-11548.
  54

• 38.

  2002

  Bharesh K. Chauhan; Weiyan Zhang; Kveta Cveklova; Marc Kantorow; Ales Cvekl

  Identification of differentially expressed genes in mouse Pax6 heterozygous lenses

  Investigative Ophthalmology and Visual Science. 2002;43(6):1884-1890.
  23

• 39.

  2002

  Nancy L. Sheets; Bharesh K. Chauhan; Eric Wawrousek; J. Fielding Hejtmancik; Ales Cvekl; Marc Kantorow

  Cataract- and lens-specific upregulation of ARK receptor tyrosine kinase in emory mouse cataract

  Investigative Ophthalmology and Visual Science. 2002;43(6):1870-1875.
  12

• 40.

  2002

  Seung-Sup Kim; Rong-Guang Zhang; Steve E. Braunstein; Andrzej Joachimiak; Ales Cvekl; Rashmi S. Hegde

  Structure of the retinal determination protein Dachshund reveals a DNA binding motif

  Structure. 2002;10(6):787-795.
  42

• 41.

  2001

  Weiyan Zhang; Kveta Cveklova; Brian Opperman; Marc Kantorow; Ales Cvekl

  Quantification of PAX6 and PAX6(5a) transcript levels in adult human lens, cornea, and monkey retina

  Molecular Vision. 2001;7:1-5.
  31

• 42.

  2000

  Lucienne Kirstein; Ales Cvekl; Bharesh K. Chauhan; Ernst R. Tamm

  Regulation of human myocilin/TIGR gene transcription in trabecular meshwork cells and astrocytes: Role of upstream stimulatory factor

  Genes to Cells. 2000;5(8):661-676.
  29

• 43.

  2000

  Melinda K. Duncan; Ales Cvekl; Xuan Li; Joram Piatigorsky

  Truncated forms of Pax-6 disrupt lens morphology in transgenic mice

  Investigative Ophthalmology and Visual Science. 2000;41(2):464-473.
  39

• 44.

  1999

  John G. Ilagan; Ales Cvekl; Marc Kantorow; Joram Piatigorsky; Christina M. Sax

  Regulation of αA-crystallin gene expression: Lens specificity achieved through the differential placement of similar transcriptional control elements in mouse and chicken

  Journal of Biological Chemistry. 1999;274(28):19973-19978.
  21

• 45.

  1999

  Zbynek Kozmik; Ales Cvekl

  Localization of the human homologue of the Drosophila dachshund gene (DACH) to chromosome 13q21

  Genomics. 1999;59(1):110-111.
  6

• 46.

  1999

  Zbynek Kozmik; Peter Pfeffer; Jarmila Kralova; Jan Paces; Vaclav Paces; Anna Kalousova; Ales Cvekl

  Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene

  Development Genes and Evolution. 1999;209(9):537-545.
  49

• 47.

  1999

  Ales Cvekl; Fatah Kashanchi; John N. Brady; Joram Piatigorsky

  Pax-6 interactions with TATA-box-binding protein and retinoblastoma protein

  Investigative Ophthalmology and Visual Science. 1999;40(7):1343-1350.
  38

• 48.

  1998

  Rashmi Gopal-Srivastava; Ales Cvekl; Joram Piatigorsky

  Involvement of retinoic acid/retinoid receptors in the regulation of murine αB-crystallin/small heat shock protein gene expression in the lens

  Journal of Biological Chemistry. 1998;273(28):17954-17961.
  46

• 49.

  1998

  Melinda K. Duncan; John I. Haynes II; Ales Cvekl; Joram Piatigorsky

  Dual roles for Pax-6: A transcriptional repressor of lens fiber cell- specific β-crystallin genes

  Molecular and Cellular Biology. 1998;18(9):5579-5586.
  92

• 50.

  1997

  Christina M. Sax; Ales Cvekl; Joram Piatigorsky

  Transcriptional regulation of the mouse αA-crystallin gene: Binding of USF to the -7/+5 region

  Gene. 1997;185(2):209-216.
  14

• 51.

  1997

  Xuan Li; Aleš Cvekl; Steven Bassnett; Joram Piatigorsky

  Lens-preferred activity of chicken δ1- and δ2-crystallin enhancers in transgenic mice and evidence for retinoic acid-responsive regulation of the δ1-crystallin gene

  Developmental Genetics. 1997;20(3):258-266.
  17

• 52.

  1997

  Joan B. McDermott; Aleš Cvekl; Joram Piatigorsky

  A complex enhancer of the chicken βA3/A1-crystallin gene depends on an AP-1-CRE element for activity

  Investigative Ophthalmology and Visual Science. 1997;38(5):951-959.
  9

• 53.

  1996

  Aleš Cvekl; Joram Piatigorsky

  Lens development and crystallin gene expression: Many roles for Pax-6

  BioEssays. 1996;18(8):621-630.
  200

• 54.

  1996

  Joan B. McDermott; Ales Cvekl; Joram Piatigorsky

  Lens-specific expression of a chicken ßA3/A1-crystallin promoter fragment in transgenic mice

  Biochemical and Biophysical Research Communications. 1996;221(3):559-564.
  9

• 55.

  1996

  Rashmi Gopal-Srivastava; Ales Cvekl; Joram Piatigorsky

  Pax-6 and αB-crystallin/small heat shock protein gene regulation in the murine lens. Interaction with the lens-specific regions, LSR1 and LSR2

  Journal of Biological Chemistry. 1996;271(38):23029-23036.
  55

• 56.

  1995

  J.F. Duvall; F. Kashanchi; A. Cvekl; M.F. Radonovich; G. Piras; J.N. Brady

  Transactivation of the human T-cell lymphotropic virus type 1 tax₁-responsive 21-base-pair repeats requires holo-TFIID and TFIIA

  Journal of Virology. 1995;69(8):5077-5086.
  20

• 57.

  1995

  A. Cvekl; F. Kashanchi; C.M. Sax; J.N. Brady; J. Piatigorsky

  Transcriptional regulation of the mouse αA-crystallin gene: Activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site

  Molecular and Cellular Biology. 1995;15(2):653-660.
  90

• 58.

  1995

  C.M. Sax; A. Cvekl; M. Kantorow; R. Gopal-Srivastava; J.G. Ilagan; N.P. Ambulos Jr.; J. Piatigorsky

  Lens-specific activity of the mouse αA-crystallin promoter in the absence of a TATA box: Functional and protein binding analysis of the mouse αA-crystallin PE1 region

  Nucleic Acids Research. 1995;23(3):442-451.
  18

• 59.

  1995

  A. Cvekl; J.B. McDermott; J. Piatigorsky

  cDNA encoding a chicken protein (CRP1) with homology to hnRNP type A/B

  Biochimica et Biophysica Acta - Gene Structure and Expression. 1995;1261(2):290-292.
  8

• 60.

  1995

  J. Richardson; A. Cvekl; G. Wistow

  Pax-6 is essential for lens-specific expression of ζ-crystallin

  Proceedings of the National Academy of Sciences of the United States of America. 1995;92(10):4676-4680.
  95

• 61.

  1995

  A. Cvekl; C.M. Sax; X. Li; J.B. McDermott; J. Piatigorsky

  Pax-6 and lens-specific transcription of the chicken δ1-crystallin gene

  Proceedings of the National Academy of Sciences of the United States of America. 1995;92(10):4681-4685.
  75

• 62.

  1994

  Aleš Cvekl; Christina M. Sax; Emery H. Bresnick; Joram Piatigorsky

  A complex array of positive and negative elements regulates the chicken αA-crystallin gene: Involvement of Pax-6, USF, CREB and/or CREM, and AP-1 proteins

  Molecular and Cellular Biology. 1994;14(11):7363-7376.
  99

• 63.

  1994

  Christina M. Sax; Ales Cvekl; Marc Kantorow; Bernd Sommer; Ana B. Chepelinsky; Joram Piatigorsky

  Identification of negative-acting and protein-binding elements in the mouse αA-crystallin -1556/-1165 region

  Gene. 1994;144(2):163-169.
  4

• 64.

  1994

  S.I. Tomarev; M.K. Duncan; H.J. Roth; A. Cvekl; J. Piatigorsky

  Convergent evolution of crystallin gene regulation in squid and chicken: The AP-1/ARE connection

  Journal of Molecular Evolution. 1994;39(2):134-143.
  18

• 65.

  1993

  K. Kantorow; A. Cvekl; C.M. Sax; J. Piatigorsky

  Protein-DNA interactions of the mouse αA-crystallin control regions. Differences between expressing and non-expressing cells

  Journal of Molecular Biology. 1993;230(2):425-435.
  11

• 66.

  1993

  J.F. Klement; A. Cvekl; J. Piatigorsky

  Functional elements DE2A, DE2B, and DE1A and the TATA box are required for activity of the chicken αA-crystallin gene in transfected lens epithelial cells

  Journal of Biological Chemistry. 1993;268(9):6777-6784.
  6

• 67.

  1992

  Aleš Cvekl; Václav Pačes

  Interactions between proteins bound to the duck β^A-globin gene promoter and enhancer detected by the DNaseI footprinting

  Gene. 1992;110(2):225-228.
  3

• 68.

  1991

  Aleš Cvekl; Květa Horská; Čestmír Vlček; Václav P`ačes

  Protein-binding A + T-rich motifs flank the duck β^A-globin enhancer

  Gene. 1991;103(2):253-257.
  4

• 69.

  1990

  A. Schnapp; J. Clos; W. Hadelt; R. Schreck; A. Cvekl; I. Grummt

  Isolation and functional characterization of TIF-IB, a factor that confers promoter specificity to mouse RNA polymerase I

  Nucleic Acids Research. 1990;18(6):1385-1393.
  18

• 70.

  1989

  Alěs Cvekl; Květa Horská; Karel Sěbesta; Ivan Rosenberg; Antoním Holý

  Phosphonate analogues of dinucleotides as substrates for DNA-dependent RNA polymerase from Escherichia coli in primed abortive initiation reaction

  International Journal of Biological Macromolecules. 1989;11(1):33-38.
  2