I. David Goldman

Medicine

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I. David Goldman

• Departments
  Medicine
  
  

718-430-2302

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Daniel Sanghoon Shin; Rongbao Zhao; Andras Fiser; I. David Goldman

  Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption

  American Journal of Physiology - Cell Physiology. 2012;303(8):C834-C842.
  0

• 2.

  2012

  Rongbao Zhao; Daniel Sanghoon Shin; Andras Fiser; I. David Goldman

  Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)

  American Journal of Physiology - Cell Physiology. 2012;303(6):C673-C681.
  1

• 3.

  2012

  Michele Visentin; Rongbao Zhao; I. David Goldman

  Augmentation of reduced folate carrier-mediated folate/antifolate transport through an antiport mechanism with 5-aminoimidazole-4-carboxamide riboside monophosphate

  Molecular Pharmacology. 2012;82(2):209-216.
  1

• 4.

  2012

  Michele Visentin; Rongbao Zhao; I. David Goldman

  The Antifolates

  Hematology/Oncology Clinics of North America. 2012;26(3):629-648.
  1

• 5.

  2012

  Daniel Sanghoon Shin; Rongbao Zhao; Enghui H. Yap; Andras Fiser; I. David Goldman

  A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding

  American Journal of Physiology - Cell Physiology. 2012;302(9):C1405-C1412.
  4

• 6.

  2012

  Michele Visentin; Min-Hwang Chang; Michael F. Romero; Rongbao Zhao; I. David Goldman

  Substrate- and pH-specific antifolate transport mediated by organic anion-transporting polypeptide 2B1 (OATP2B1-SLCO2B1)

  Molecular Pharmacology. 2012;81(2):134-142.
  2

• 7.

  2011

  Kris M. Mahadeo; Ndeye Diop-Bove; Sonia I. Ramirez; Carmen L. Cadilla; Enid Rivera; Madelena Martin; Norma B. Lerner; Lisa Diantonio; Salvatore Duva; Pedro J. Santiago-Borrero; et al.

  Prevalence of a loss-of-function mutation in the proton-coupled folate transporter gene (PCFT-SLC46A1) causing hereditary folate malabsorption in Puerto Rico

  Journal of Pediatrics. 2011;159(4):623-627.e1.
  1

• 8.

  2011

  Rongbao Zhao; Ndeye Diop-Bove; Michele Visentin; I. David Goldman

  Mechanisms of membrane transport of folates into cells and across epithelia

  Annual Review of Nutrition. 2011;31:177-201.
  20

• 9.

  2011

  Rongbao Zhao; Daniel Sanghoon Shin; Ndeye Diop-Bove; Channa Gila Ovits; I. David Goldman

  Random mutagenesis of the proton-coupled folate transporter (SLC46A1), clustering of mutations, and the bases for associated losses of function

  Journal of Biological Chemistry. 2011;286(27):24150-24158.
  5

• 10.

  2011

  Daniel Sanghoon Shin; Kris Mahadeo; Sang Hee Min; Ndeye Diop-Bove; Peter Clayton; Rongbao Zhao; I. David Goldman

  Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption

  Molecular Genetics and Metabolism. 2011;103(1):33-37.
  7

• 11.

  2011

  Rongbao Zhao; Daniel Sanghoon Shin; I. David Goldman

  Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method

  Biochimica et Biophysica Acta - Biomembranes. 2011;1808(4):1140-1145.
  3

• 12.

  2010

  Daniel Sanghoon Shin; Sang Hee Min; Laura Russell; Rongbao Zhao; Andras Fiser; I. David Goldman

  Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption

  Blood. 2010;116(24):5162-5169.
  11

• 13.

  2010

  I. David Goldman; Shrikanta Chattopadhyay; Rongbao Zhao; Richard Moran

  The antifolates: Evolution, new agents in the clinic, and how targeting delivery via specific membrane transporters is driving the development of a next generation of folate analogs

  Current Opinion in Investigational Drugs. 2010;11(12):1409-1423.
  17

• 14.

  2010

  Kris Mahadeo; Ndeye Diop-Bove; Daniel Shin; Ersin Selcuk Unal; Juliana Teo; Rongbao Zhao; Min-Hwang Chang; Andreas Fulterer; Michael F. Romero; I. David Goldman

  Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

  American Journal of Physiology - Cell Physiology. 2010;299(5):C1153-C1161.
  11

• 15.

  2010

  Berna Atabay; Meral Turker; Esra Arun Ozer; Kris Mahadeo; Ndeye Diop-Bove; I. David Goldman

  Mutation of the proton-coupled folate transporter gene (PCFT-SLC46A1) in Turkish siblings with hereditary folate malabsorption

  Pediatric Hematology and Oncology. 2010;27(8):614-619.
  9

• 16.

  2010

  B. Renee Bozard; Preethi S. Ganapathy; Jennifer Duplantier; Barbara Mysona; Yonju Ha; Penny Roon; Robert Smith; I. David Goldman; Puttur Prasad; Pamela M. Martin; et al.

  Molecular and biochemical characterization of folate transport proteins in retinal müller cells

  Investigative Ophthalmology and Visual Science. 2010;51(6):3226-3235.
  7

• 17.

  2010

  Rongbao Zhao; Ersin Selcuk Unal; Daniel Sanghoon Shin; I. David Goldman

  Membrane topological analysis of the proton-coupled folate transporter (PCFT-SLC46A1) by the substituted cysteine accessibility method

  Biochemistry. 2010;49(13):2925-2931.
  14

• 18.

  2009

  Rongbao Zhao; Larry H. Matherly; I. David Goldman

  Membrane transporters and folate homeostasis: Intestinal absorption and transport into systemic compartments and tissues

  Expert Reviews in Molecular Medicine. 2009;11.
  71

• 19.

  2009

  Ndeye Khady Diop-Bove; Julia Wu; Rongbao Zhao; Joseph Locker; I. David Goldman

  Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal trancriptional regulatory region in an antifolate-resistant HeLa cell line

  Molecular Cancer Therapeutics. 2009;8(8):2424-2431.
  18

• 20.

  2009

  Ersin Selcuk Unal; Rongbao Zhao; I. David Goldman

  Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1

  American Journal of Physiology - Cell Physiology. 2009;297(1):C66-C74.
  17

• 21.

  2009

  Ersin Selcuk Unal; Rongbao Zhao; Min-Hwang Chang; Andras Fiser; Michael F. Romero; I. David Goldman

  The functional roles of the His²⁴⁷ and His²⁸¹ residues in folate and proton translocation mediated by the human proton-coupled folate transporter SLC46A1

  Journal of Biological Chemistry. 2009;284(26):17846-17857.
  20

• 22.

  2009

  Rongbao Zhao; Sang Hee Min; Yanhua Wang; Estela Campanella; Philip S. Low; I. David Goldman

  A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis

  Journal of Biological Chemistry. 2009;284(7):4267-4274.
  36

• 23.

  2008

  Rongbao Zhao; Andong Qiu; Eugenia Tsai; Michaela Jansen; Myles H. Akabas; I. David Goldman

  The proton-coupled folate transporter: Impact on pemetrexed transport and on antifolates activities compared with the reduced folate carrier

  Molecular Pharmacology. 2008;74(3):854-862.
  45

• 24.

  2008

  Sang Hee Min; Sun Young Oh; George I. Karp; Mortimer Poncz; Rongbao Zhao; I. David Goldman

  The Clinical Course and Genetic Defect in the PCFT Gene in a 27-Year-Old Woman with Hereditary Folate Malabsorption

  Journal of Pediatrics. 2008;153(3):435-437.
  20

• 25.

  2008

  Paolo Moretti; Sarika U. Peters; Daniela Del Gaudio; Trilochan Sahoo; Keith Hyland; Teodoro Bottiglieri; Robert J. Hopkin; Elizabeth Peach; Sang Hee Min; David Goldman; et al.

  Brief report: Autistic symptoms, developmental regression, mental retardation, epilepsy, and dyskinesias in CNS folate deficiency

  Journal of Autism and Developmental Disorders. 2008;38(6):1170-1177.
  21

• 26.

  2008

  Ersin Selcuk Unal; Rongbao Zhao; Andong Qiu; I. David Goldman

  N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT)

  Biochimica et Biophysica Acta - Biomembranes. 2008;1778(6):1407-1414.
  8

• 27.

  2008

  Sang Hee Min; I. David Goldman; Rongbao Zhao

  Caffeine markedly sensitizes human mesothelioma cell lines to pemetrexed

  Cancer Chemotherapy and Pharmacology. 2008;61(5):819-827.
  5

• 28.

  2008

  Jan B. Wollack; Benedette Makori; Stuti Ahlawat; Rajeth Koneru; Sonia C. Picinich; Angela Smith; I. David Goldman; Andong Qiu; Peter D. Cole; et al.

  Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model

  Journal of Neurochemistry. 2008;104(6):1494-1503.
  22

• 29.

  2007

  Andong Qiu; Hee Min Sang; Michaela Jansen; Usha Malhotra; Eugenia Tsai; Diane C. Cabelof; Larry H. Matherly; Rongbao Zhao; Myles H. Akabas; I. David Goldman

  Rodent intestinal folate transporters (SLC46A1): Secondary structure, functional properties, and response to dietary folate restriction

  American Journal of Physiology - Cell Physiology. 2007;293(5):C1669-C1678.
  48

• 30.

  2007

  Rongbao Zhao; Hee Min Sang; Andong Qiu; Antoinette Sakaris; Gary L. Goldberg; Claudio Sandoval; J. Jeffrey Malatack; David S. Rosenblatt; I. David Goldman

  The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorption

  Blood. 2007;110(4):1147-1152.
  58

• 31.

  2007

  Shrikanta Chattopadhyay; Roni Tamari; Sang H. Min; Rongbao Zhao; Eugenia Tsai; I. David Goldman

  Commentary: A case for minimizing folate supplementation in clinical regimens with pemetrexed based on the marked sensitivity of the drug to folate availability

  Oncologist. 2007;12(7):808-815.
  20

• 32.

  2007

  Tianhong Li; Yi-He Ling; I. David Goldman; Roman Perez-Soler

  Schedule-dependent cytotoxic synergism of pemetrexed and erlotinib in human non-small cell lung cancer cells

  Clinical Cancer Research. 2007;13(11):3413-3422.
  66

• 33.

  2007

  Rongbao Zhao; I. David Goldman

  The molecular identity and characterization of a Proton-Coupled Folate Transporter - PCFT; biological ramifications and impact on the activity of pemetrexed-12 06 06

  Cancer and Metastasis Reviews. 2007;26(1):129-139.
  43

• 34.

  2007

  Shrikanta Chattopadhyay; Richard G. Moran; I. David Goldman

  Pemetrexed: Biochemical and cellular pharmacology, mechanisms, and clinical applications

  Molecular Cancer Therapeutics. 2007;6(2):404-417.
  77

• 35.

  2006

  Andong Qiu; Michaela Jansen; Antoinette Sakaris; Sang Hee Min; Shrikanta Chattopadhyay; Eugenia Tsai; Claudio Sandoval; Rongbao Zhao; Myles H. Akabas; et al.

  Identification of an Intestinal Folate Transporter and the Molecular Basis for Hereditary Folate Malabsorption

  Cell. 2006;127(5):917-928.
  258

• 36.

  2006

  Shrikanta Chattopadhyay; Rongbao Zhao; Eugenia Tsai; Vern L. Schramm; I. David Goldman

  The effect of a novel transition state inhibitor of methylthioadenosine phosphorylase on pemetrexed activity

  Molecular Cancer Therapeutics. 2006;5(10):2549-2555.
  11

• 37.

  2006

  Shrikanta Chattopadhyay; Rongbao Zhao; Sergery A. Krupenko; Natalia Krupenko; I. David Goldman

  The inverse relationship between reduced folate carrier function and pemetrexed activity in a human colon cancer cell line

  Molecular Cancer Therapeutics. 2006;5(2):438-449.
  30

• 38.

  2005

  Rongbao Zhao; Marie Hanscom; I. David Goldman

  The relationship between folate transport activity at low pH and reduced folate carrier function in human Huh7 hepatoma cells

  Biochimica et Biophysica Acta - Biomembranes. 2005;1715(1):57-64.
  9

• 39.

  2005

  Rongbao Zhao; Shubing Zhang; Marie Hanscom; Shrikanta Chattopadhyay; I. David Goldman

  Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis

  Clinical Cancer Research. 2005;11(3):1294-1301.
  18

• 40.

  2005

  Yanhua Wang; Arun Rajgopal; I. David Goldman; Rongbao Zhao

  Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function

  American Journal of Physiology - Cell Physiology. 2005;288(1 57-1):C65-C71.
  17

• 41.

  2004

  Rongbao Zhao; Shrikanta Chattopadhyay; Marie Hanscom; I. David Goldman

  Antifolate resistance in a HeLa cell line associated with impaired transport independent of the reduced folate carrier

  Clinical Cancer Research. 2004;10(24):8735-8742.
  30

• 42.

  2004

  Shrikanta Chattopadhyay; Yanhua Wang; Rongbao Zhao; I. David Goldman

  Lack of impact of the loss of constitutive folate receptor α expression, achieved by RNA interference, on the activity of the new generation antifolate pemetrexed in HeLa cells

  Clinical Cancer Research. 2004;10(23):7986-7993.
  15

• 43.

  2004

  Yanhua Wang; Rongbao Zhao; I. David Goldman

  Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier

  Clinical Cancer Research. 2004;10(18 I):6256-6264.
  41

• 44.

  2004

  Rongbao Zhao; Marie Hanscom; Shrikanta Chattopadhyay; I. David Goldman

  Selective Preservation of Pemetrexed Pharmacological Activity in HeLa Cells Lacking the Reduced Folate Carrier: Association with the Presence of a Secondary Transport Pathway

  Cancer Research. 2004;64(9):3313-3319.
  35

• 45.

  2004

  Rongbao Zhao; Feng Gao; Marie Hanscom; I. David Goldman

  A Prominent Low-pH Methotrexate Transport Activity in Human Solid Tumors: Contribution to the Preservation of Methotrexate Pharmacologic Activity in HeLa Cells Lacking the Reduced Folate Carrier

  Clinical Cancer Research. 2004;10(2):718-727.
  59

• 46.

  2004

  Rongbao Zhao; I. David Goldman

  Enter Alimta®: A new generation antifolate

  Oncologist. 2004;9(3):242-244.
  11

• 47.

  2003

  Rongbao Zhao; I. David Goldman

  Resistance to antifolates

  Oncogene. 2003;22(47 REV. ISS. 6):7431-7457.
  127

• 48.

  2003

  Michal Stark; Lilah Rothem; Gerrit Jansen; George L. Scheffer; David I. Goldman; Yehuda G. Assaraf

  Antifolate resistance associated with loss of MRP1 expression and function in Chinese hamster ovary cells with markedly impaired export of folate and cholate

  Molecular Pharmacology. 2003;64(2):220-227.
  24

• 49.

  2003

  Rongbao Zhao; Yanhua Wang; Feng Gao; I. David Goldman

  Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility

  Biochimica et Biophysica Acta - Biomembranes. 2003;1613(1-2):49-56.
  4

• 50.

  2003

  Yanhua Wang; Rongboa Zhao; I. David Goldman

  Decreased expression of the reduced folate carrier and folypolyglutamate synthetase is the basis for acquired resistance to the pemetrexed antifolate (LY231514) in an L1210 murine leukemia cell line

  Biochemical Pharmacology. 2003;65(7):1163-1170.
  34

• 51.

  2003

  Larry H Matherly; I.David Goldman

  Membrane Transport of Folates

  Vitamins and Hormones. 2003;66:403-456.
  195

• 52.

  2002

  I. David Goldman; Rongbao Zhao

  Molecular, biochemical, and cellular pharmacology of pemetrexed

  Seminars in Oncology. 2002;29(6 SUPPL. 18):3-17.
  59

• 53.

  2002

  Yanhua Wang; Rongbao Zhao; Shrikanta Chattopadhyay; I. David Goldman

  A novel folate transport activity in human mesothelioma cell lines with high affinity and specificity for the new-generation antifolate, pemetrexed

  Cancer Research. 2002;62(22):6434-6437.
  23

• 54.

  2002

  Iraida G. Sharina; Rongbao Zhao; Yanhua Wang; Solomon Babani; I.David Goldman

  Role of the C-terminus and the long cytoplasmic loop in reduced folate carrier expression and function

  Biochemical Pharmacology. 2002;63(9):1717-1724.
  11

• 55.

  2002

  Rongbao Zhao; Feng Gao; I. David Goldman

  Reduced folate carrier transports thiamine monophosphate: An alternative route for thiamine delivery into mammalian cells

  American Journal of Physiology - Cell Physiology. 2002;282(6 51-6):C1512-C1517.
  44

• 56.

  2002

  I. David Goldman

  Membrane transport of chemotherapeutics and drug resistance: Beyond the ABC family of exporters to the role of carrier-mediated processes

  Clinical Cancer Research. 2002;8(1):4-6.
  4

• 57.

  2001

  Arun Rajgopal; Antoinette Edmondnson; I.David Goldman; Rongbao Zhao

  SLC19A3 encodes a second thiamine transporter ThTr2

  Biochimica et Biophysica Acta - Molecular Basis of Disease. 2001;1537(3):175-178.
  65

• 58.

  2001

  Yanhua Wang; Rongbao Zhao; Robert G Russell; I.David Goldman

  Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis

  Biochimica et Biophysica Acta - Biomembranes. 2001;1513(1):49-54.
  76

• 59.

  2001

  Rongbao Zhao; Feng Gao; I.David Goldman

  Marked suppression of the activity of some, but not all, antifolate compounds by augmentation of folate cofactor pools within tumor cells

  Biochemical Pharmacology. 2001;61(7):857-865.
  45

• 60.

  2001

  Rongbao Zhao; Robert G. Russell; Yanhua Wang; Laibin Liu; Feng Gao; Burkhard Kneitz; Winfried Edelmann; I. David Goldman

  Rescue of Embryonic Lethality in Reduced Folate Carrier-deficient Mice by Maternal Folic Acid Supplementation Reveals Early Neonatal Failure of Hematopoietic Organs

  Journal of Biological Chemistry. 2001;276(13):10224-10228.
  70

• 61.

  2001

  Rongbao Zhao; Feng Gao; I.David Goldman

  Molecular cloning of human thiamin pyrophosphokinase

  Biochimica et Biophysica Acta - Gene Structure and Expression. 2001;1517(2):320-322.
  10

• 62.

  2001

  Rongbao Zhao; Feng Gao; Yanhua Wang; George A. Diaz; Bruce D. Gelb; I. David Goldman

  Impact of the reduced folate carrier on the accumulation of active thiamin metabolites in murine leukemia cells

  Journal of Biological Chemistry. 2001;276(2):1114-1118.
  49

• 63.

  2001

  Iraida G. Sharina; Rongbao Zhao; Yanhua Wang; Solomon Babani; I. David Goldman

  Mutational analysis of the functional role of conserved arginine and lysine residues in transmembrane domains of the murine reduced folate carrier

  Molecular Pharmacology. 2001;59(5):1022-1028.
  25

• 64.

  2001

  Arun Rajgopal; Esteban E. Sierra; Rongbao Zhao; I. David Goldman

  Expression of the reduced folate carrier SLC19A1 in IEC-6 cells results in two distinct transport activities

  American Journal of Physiology - Cell Physiology. 2001;281(5 50-5):C1579-C1586.
  33

• 65.

  2000

  Rongbao Zhao; Steven Titus; Feng Gao; Richard G. Moran; I. David Goldman

  Molecular analysis of murine leukemia cell lines resistant to 5,10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase

  Journal of Biological Chemistry. 2000;275(34):26599-26606.
  25

• 66.

  2000

  Rongbao Zhao; Feng Gao; Solomon Babani; I. David Goldman

  Sensitivity to 5,10-dideazatetrahydrofolate is fully conserved in a murine leukemia cell line highly resistant to methotrexate due to impaired transport mediated by the reduced folate carrier

  Clinical Cancer Research. 2000;6(8):3304-3311.
  16

• 67.

  2000

  Rongbao Zhao; Feng Gao; Laibin Liu; I. David Goldman

  The reduced folate carrier in L1210 murine leukemia cells is a 58-kDa protein

  Biochimica et Biophysica Acta - Biomembranes. 2000;1466(1-2):7-10.
  13

• 68.

  2000

  R. Zhao; S. Babani; F. Gao; L. Liu; I.D. Goldman

  The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate

  Clinical Cancer Research. 2000;6(9):3687-3695.
  69

• 69.

  2000

  Stavit Drori; Hannah Sprecher; Gidi Shemer; Gerrit Jansen; I. David Goldman; Yehuda G. Assaraf

  Characterization of a human alternatively spliced truncated reduced folate carrier increasing folate accumulation in parental leukemia cells

  European Journal of Biochemistry. 2000;267(3):690-702.
  17

• 70.

  2000

  Rongbao Zhao; Feng Gao; Pi Jun Wang; I. David Goldman

  Role of the amino acid 45 residue in reduced folate carrier function and ion-dependent transport as characterized by site-directed mutagenesis

  Molecular Pharmacology. 2000;57(2):317-323.
  17

• 71.

  2000

  Karim A. Sharif; I. David Goldman

  Rapid determination of membrane transport parameters in adherent cells

  BioTechniques. 2000;28(5):926-932.
  20

• 72.

  1999

  Rongbao Zhao; Feng Gao; I. David Goldman

  Discrimination among reduced folates and methotrexate as transport substrates by a phenylalanine substitution for serine within the predicted eighth transmembrane domain of the reduced folate carrier

  Biochemical Pharmacology. 1999;58(10):1615-1624.
  23

• 73.

  1999

  Yehuda G. Assaraf; Esteban E. Sierra; Solomon Babani; I. David Goldman

  Inhibitory effects of prostaglandin A₁ on membrane transport of folates mediated by both the reduced folate carrier and ATP-driven exporters

  Biochemical Pharmacology. 1999;58(8):1321-1327.
  13

• 74.

  1999

  E.E. Sierra; I.D. Goldman

  Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates

  Seminars in Oncology. 1999;26(2 SUUPL.):11-23.
  72

• 75.

  1999

  Rongbao Zhao; Iraida G. Sharina; I. David Goldman

  Pattern of mutations that results in loss of reduced folate carrier function under antifolate selective pressure augmented by chemical mutagenesis

  Molecular Pharmacology. 1999;56(1):68-76.
  51

• 76.

  1998

  Rongbao Zhao; Yehuda G. Assaraf; I. David Goldman

  A mutated murine reduced folate carrier (RFC1) with increased affinity for folic acid, decreased affinity for methotrexate, and an obligatory anion requirement for transport function

  Journal of Biological Chemistry. 1998;273(30):19065-19071.
  53

• 77.

  1998

  Karim A. Sharif; Jeffrey A. Moscow; I. David Goldman

  Concentrating capacity of the human reduced folate carrier (hRFC1) in human ZR-75 breast cancer cell lines

  Biochemical Pharmacology. 1998;55(10):1683-1689.
  7

• 78.

  1998

  Esteban E. Sierra; I. David Goldman

  Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function

  Biochemical Pharmacology. 1998;55(9):1505-1512.
  28

• 79.

  1998

  Yehuda G. Assaraf; Solomon Babani; I. David Goldman

  Increased activity of a novel low pH folate transporter associated with lipophilic antifolate resistance in Chinese hamster ovary cells

  Journal of Biological Chemistry. 1998;273(14):8106-8111.
  35

• 80.

  1998

  Rongbao Zhao; Yehuda G. Assaraf; I. David Goldman

  A reduced folate carrier mutation produces substrate-dependent alterations in carrier mobility in murine leukemia cells and methotrexate resistance with conservation of growth in 5-formyltetrahydrofolate

  Journal of Biological Chemistry. 1998;273(14):7873-7879.
  67

• 81.

  1997

  Rongbao Zhao; Richard Seither; Kevin E. Brigle; Iraida G. Sharina; Pi J. Wang; I. David Goldman

  Impact of overexpression of the reduced folate carrier (RFC1), an anion exchanger, on concentrative transport in murine L1210 leukemia cells

  Journal of Biological Chemistry. 1997;272(34):21207-21212.
  50

• 82.

  1997

  Kevin E. Brigle; Michael J. Spinella; Esteban E. Sierra; I. David Goldman

  Organization of the murine reduced folate carrier gene and identification of variant splice forms

  Biochimica et Biophysica Acta - Gene Structure and Expression. 1997;1353(2):191-198.
  20

• 83.

  1997

  Esteban E. Sierra; Kevin E. Brigle; Michael J. Spinella; I. David Goldman

  pH dependence of methotrexate transport by the reduced folate carrier and the folate receptor in L1210 leukemia cells. Further evidence for a third route mediated at low pH

  Biochemical Pharmacology. 1997;53(2):223-231.
  45

• 84.

  1997

  Yehuda G. Assaraf; I. David Goldman

  Loss of folic acid exporter function with markedly augmented folate accumulation in lipophilic antifolate-resistant mammalian cells

  Journal of Biological Chemistry. 1997;272(28):17460-17466.
  47

• 85.

  1996

  Michael J. Spinella; Kevin E. Brigle; Sarah J. Freemantle; Esteban E. Sierra; I. David Goldman

  Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects

  Biochemical Pharmacology. 1996;52(5):703-712.
  14

• 86.

  1996

  Michael J. Spinella; Kevin E. Brigle; I. David Goldman

  Molecular cloning of murine folylpoly-γ-glutamate synthetase

  Biochimica et Biophysica Acta - Gene Structure and Expression. 1996;1305(1-2):11-14.
  7

• 87.

  1995

  Esteban E. Sierra; Kevin E. Brigle; Michael J. Spinella; I. David Goldman

  Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells

  Biochemical Pharmacology. 1995;50(8):1287-1294.
  22

• 88.

  1995

  M.J. Spinella; K.E. Brigle; E.E. Sierra; I.D. Goldman

  Distinguishing between folate receptor-α-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells

  Journal of Biological Chemistry. 1995;270(14):7842-7849.
  73

• 89.

  1995

  K.E. Brigle; M.J. Spinella; E.E. Sierra; I.D. Goldman

  Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

  Journal of Biological Chemistry. 1995;270(39):22974-22979.
  95

• 90.

  1994

  Kevin E. Brigle; Richard L. Seither; Eric H. Westin; I. David Goldman

  Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier

  Journal of Biological Chemistry. 1994;269(6):4267-4272.
  16

• 91.

  1994

  K.E. Brigle; M.J. Spinella; E.H. Westin; I.D. Goldman

  Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells

  Biochemical Pharmacology. 1994;47(2):337-345.
  60

• 92.

  1992

  K.E. Brigle; E.H. Westin; M.T. Houghton; I.D. Goldman

  Insertion of an intracisternal A particle within the 5'-regulatory region of a gene encoding folate-binding protein in L1210 leukemia cells in response to low folate selection. Association with increased protein expression

  Journal of Biological Chemistry. 1992;267(31):22351-22355.
  15

• 93.

  1992

  R.L. Seither; T.J. Rape; I.D. Goldman

  Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells

  Biochemical Pharmacology. 1992;43(12):2647-2654.
  0

• 94.

  1991

  D.F. Trent; R.L. Seither; I.D. Goldman

  Compartmentation of intracellular folates. Failure to interconvert tetrahydrofolate cofactors to dihydrofolate in mitochondria of L1210 leukemia cells treated with trimetrexate

  Biochemical Pharmacology. 1991;42(5):1015-1019.
  14

• 95.

  1991

  K.E. Brigle; E.H. Westin; M.T. Houghton; I.D. Goldman

  Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement

  Journal of Biological Chemistry. 1991;266(26):17243-17249.
  55

• 96.

  1991

  D.F. Trent; R.L. Seither; I.D. Goldman

  Rate and extent of interconversion of tetrahydrofolate cofactors to dihydrofolate after cessation of dihydrofolate reductase activity in stationary versus log phase L1210 leukemia cells

  Journal of Biological Chemistry. 1991;266(9):5445-5449.
  3

• 97.

  1991

  R.L. Seither; D.F. Trent; D.C. Mikulecky; T.J. Rape; I.D. Goldman

  Effect of direct suppression of thymidylate synthase at the 5,10-methylenetetrahydrofolate binding site on the interconversion of tetrahydrofolate cofactors to dihydrofolate by antifolates: Influence of degree of dihydrofolate reductase inhibition

  Journal of Biological Chemistry. 1991;266(7):4112-4118.
  6

• 98.

  1990

  William B. Strong; Saul J. Tendler; Richard L. Seither; I. David Goldman; Verne Schirch

  Purification and properties of serine hydroxymethyltransferase and C₁-tetrahydrofolate synthase from L1210 cells

  Journal of Biological Chemistry. 1990;265(21):12149-12155.
  21

• 99.

  1990

  R. Pincus; I.D. Goldman

  Evidence for impaired mitoxantrone and vinblastine binding in P388 murine leukemia cells with multidrug resistance

  Biochemical Pharmacology. 1990;40(12):2625-2635.
  5

• 100.

  1989

  R.L. Seither; D.F. Trent; D.C. Mikulecky; T.J. Rape; I.D. Goldman

  Folate-pool interconversions and inhibition of biosynthetic processes after exposure of L1210 leukemia cells to antifolates. Experimental and network thermodynamic analyses of the role of dihydrofolate polyglutamylates in antifolate action in cells

  Journal of Biological Chemistry. 1989;264(29):17016-17023.
  31

• 101.

  1989

  J.D. Schuetz; E.H. Westin; L.H. Matherly; R. Pincus; P.S. Swerdlow; I.D. Goldman

  Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier

  Journal of Biological Chemistry. 1989;264(27):16261-16267.
  16

• 102.

  1989

  L.H. Matherly; J.D. Schuetz; E. Westin; I.D. Goldman

  A method for the synchronization of cultured cells with aphidicolin: Application to the large-scale synchronization of L1210 cells and the study of the cell cycle regulation of thymidylate synthase and dihydrofolate reductase

  Analytical Biochemistry. 1989;182(2):338-345.
  31

• 103.

  1989

  R.L. Seither; T.J. Rape; I.D. Goldman

  Further studies on the pharmacologic effects of the 7-hydroxy catabolite of methotrexate in the L1210 murine leukemia cell

  Biochemical Pharmacology. 1989;38(5):815-822.
  5

• 104.

  1988

  J.D. Schuetz; K.M. Gorse; I.D. Goldman; E.H. Westin

  Transient inhibition of DNA synthesis by 5-fluorodeoxyuridine leads to overexpression of dihydrofolate reductase with increased frequency of methotrexate resistance.

  Journal of Biological Chemistry. 1988;263(16):7708-7712.
  3

• 105.

  1988

  J.D. Schuetz; L.H. Matherly; E.H. Westin; I.D. Goldman

  Evidence for a functional defect in the translocation of the methotrexate transport carrier in a methotrexate-resistant murine L1210 leukemia cell line

  Journal of Biological Chemistry. 1988;263(20):9840-9847.
  44

• 106.

  1987

  L.H. Matherly; C.K. Barlowe; V.M. Phillips; I.D. Goldman

  The effects of 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. A biochemical basis of the selectivity of leucovorin rescue

  Journal of Biological Chemistry. 1987;262(2):710-717.
  21

• 107.

  1987

  G.L. Wampler; W.H. Carter Jr.; E.D. Campbell; I.D. Goldman

  Demonstration of a schedule-dependent therapeutic synergism utilizing the interacting drugs methotrexate and teniposide in L1210 leukemia

  Cancer Treatment Reports. 1987;71(6):581-591.
  0

• 108.

  1987

  I.D. Goldman; L.H. Matherly

  Biochemical factors in the selectivity of leucovorin rescue: Selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates

  NCI Monographs. 1987;(5):17-26.
  3

• 109.

  1987

  L.H. Matherly; R.L. Seither; I.D. Goldman

  Metabolism of the diaminoantifolates: Biosynthesis and pharmacology of the 7-hydroxyl and polyglutamyl metabolites of methotrexate and related antifolates

  Pharmacology and Therapeutics. 1987;35(1-2):27-56.
  10

• 110.

  1986

  G. Fabre; R. Seither; I.D. Goldman

  Hydroxylation of 4-amino-antifolates by partially purified aldehyde oxidase from rabbit liver

  Biochemical Pharmacology. 1986;35(8):1325-1330.
  13

• 111.

  1986

  L.H. Matherly; C.K. Barlowe; I.D. Goldman

  Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells

  Cancer Research. 1986;46(2):588-593.
  15

• 112.

  1985

  I.D. Goldman; L.H. Matherly

  The cellular pharmacology of methotrexate

  Pharmacology and Therapeutics. 1985;28(1):77-102.
  116

• 113.

  1985

  M. Eleff; P.E. Franks; G.L. Wampler; J.M. Collins; I.D. Goldman

  Analysis of 'early' thymidine/inosine protection as an adjunct to methotrexate therapy

  Cancer Treatment Reports. 1985;69(7-8):867-874.
  0

• 114.

  1985

  G. Fabre; I. Fabre; D.A. Gewirtz; I.D. Goldman

  Characteristics of the formation and membrane transport of 7-hydroxymethotrexate in freshly isolated rabbit hepatocytes

  Cancer Research. 1985;45(3):1086-1091.
  2

• 115.

  1985

  G. Fabre; I.D. Goldman

  Formation of 7-hydroxymethotrexate polyglutamyl derivatives and their cytotoxicity in human chronic myelogenous leukemia cells, in vitro

  Cancer Research. 1985;45(1):80-85.
  9

• 116.

  1985

  L.H. Matherly; M.K. Voss; L.A. Anderson; D.W. Fry; I.D. Goldman

  Enhanced polyglutamylation of aminopterin relative to methotrexate in the Ehrlich ascites tumor cell in vitro

  Cancer Research. 1985;45(3):1073-1078.
  6

• 117.

  1984

  I. Fabre; G. Fabre; I.D. Goldman

  Polyglutamylation, an important element in methotrexate cytotoxicity and selectivity in tumor versus murine granulocytic progenitor cells in vitro

  Cancer Research. 1984;44(8):3190-3195.
  35

• 118.

  1984

  D.A. Gewirtz; J.K. Randolph; I.D. Goldman

  Induction of taurocholate release from isolated rat hepatocytes in suspension by α-adrenergic agents and vasopressin: Implications for control of bile salt secretion

  Hepatology. 1984;4(2):205-212.
  3

• 119.

  1984

  L.H. Matherly; L.A. Anderson; I.D. Goldman

  Role of the cellular oxidation-reduction state in methotrexate binding to dihydrofolate reductase and dissociation induced by reduced folates

  Cancer Research. 1984;44(6):2325-2330.
  4

• 120.

  1984

  J.C. Yalowich; I.D. Goldman

  Analysis of the inhibitory effects of VP-16-213 (etoposide) and podophyllotoxin on thymidine transport and metabolism in Ehrlich ascites tumor cells in vitro

  Cancer Research. 1984;44(3):984-989.
  6

• 121.

  1984

  G. Fabre; I. Fabre; L.H. Matherly; J.P. Cano; I.D. Goldman

  Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro

  Journal of Biological Chemistry. 1984;259(8):5066-5072.
  11

• 122.

  1984

  G. Fabre; L.H. Matherly; I. Fabre; J.P. Cano; I.D. Goldman

  Interactions between 7-hydroxymethotrexate and methotrexate at the cellular level in the Ehrlich ascites tumor in vitro

  Cancer Research. 1984;44(3):970-975.
  8

• 123.

  1983

  D.W. Fry; L.A. Anderson; M. Borst; I.D. Goldman

  Analysis of the role of membrane transport and polyglutamation of methotrexate in gut and the Ehrlich tumor in vivo as factors in drug sensitivity and selectivity

  Cancer Research. 1983;43(3):1087-1092.
  22

• 124.

  1983

  L.H. Matherly; D.W. Fry; I.D. Goldman

  Role of methotrexate polyglutamylation and cellular energy metabolism in inhibition of methotrexate binding to dihydrofolate reductase by 5-formyltetrahydrofolate in Ehrlich ascites tumor cells in vitro

  Cancer Research. 1983;43(6):2694-2699.
  7

• 125.

  1983

  D.W. Fry; D.A. Gewirtz; J.C. Yalowich; I.D. Goldman

  Characteristics of the accumulation of methotrexate polyglutamate derivatives in Ehrlich ascites tumor cells and isolated rat hepatocytes.

  Advances in Experimental Medicine and Biology. 1983;163:215-234.
  1

• 126.

  1982

  J.C. Yalowich; D.W. Fry; I.D. Goldman

  Teniposide (VM-26)- and etoposide (VP-16-213)-induced augmentation of methotrexate transport and polyglutamylation in Ehrlich ascites tumor cells in vitro

  Cancer Research. 1982;42(9):3648-3653.
  8

• 127.

  1982

  D.A. Gewirtz; J.K. Randolph; I.D. Goldman

  Catecholamine-induced release of the folic acid analogue, Methotrexate, from rat hepatocytes in suspension. An alpha-adrenergic phenomenon

  Molecular Pharmacology. 1982;22(2):493-499.
  0

• 128.

  1982

  D.W. Fry; J.C. Yalowich; I.D. Goldman

  Augmentation of the intracellular levels of polyglutamyl derivatives of methotrexate by vincristine and probenecid in Ehrlich ascites tumor cells

  Cancer Research. 1982;42(7):2532-2536.
  2

• 129.

  1982

  D.W. Fry; J.C. Yalowich; I.D. Goldman

  Rapid formation of poly-γ-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro

  Journal of Biological Chemistry. 1982;257(4):1890-1896.
  71

• 130.

  1982

  D.W. Fry; I.D. Goldman

  Further studies on the charge-related alterations of methotrexate transport in Ehrlich ascites tumor cells by ionic liposomes: Correlation with liposome-cell association

  Journal of Membrane Biology. 1982;66(2):87-95.
  7

• 131.

  1982

  R.L. Cybulski; D.W. Fry; I.D. Goldman

  Approaches to the measurement of intracellular adenine and the discrimination between adenine transport and metabolism in L1210 leukemia cells

  Biochimica et Biophysica Acta. 1982;714(3):435-441.
  1

• 132.

  1981

  J.C. White; I.D. Goldman

  Methotrexate resistance in an L1210 cell line resulting from increased dihydrofolate reductase, decreased thymidylate synthetase activity, and normal membrane transport. Computer simulations based on network thermodynamics

  Journal of Biological Chemistry. 1981;256(11):5722-5727.
  11

• 133.

  1981

  D. Goldman; D. Bowen; D.A. Gewirtz

  Some considerations in the experimental approach to distinguishing between membrane transport and intracellular disposition of antineoplastic agents, with specific reference to fluorodeoxyuridine, actinomycin D, and methotrexate

  Cancer Treatment Reports. 1981;65(Suppl. 3):43-56.
  4

• 134.

  1981

  I.D. Goldman

  Membrane transport considerations in high-dose methotrexate regimens with leucovorin rescue

  Cancer Treatment Reports. 1981;65(Suppl.1):13-17.
  1

• 135.

  1981

  D.A. Gewirtz; J.K. Randolph; I.D. Goldman

  Efflux in isolated hepatocytes as a possible correlate of secretion in vivo: Induced exit of the folic acid analog, methotrexate, by dibutyryl cyclic AMP or isobutyl methyl xanthine

  Biochemical and Biophysical Research Communications. 1981;101(2):366-374.
  2

• 136.

  1981

  R.L. Cybulski; D.W. Fry; I.D. Goldman

  Adenosine stimulation of uphill adenine transport in L1210 leukemia cells. Evidence for a novel countertransport mechanism

  Journal of Biological Chemistry. 1981;256(9):4455-4459.
  0

• 137.

  1980

  David W. Fry; Raymond L. Cybulski; I.David Goldman

  K⁺-induced alterations of energetics and exchange diffusion in the carrier-mediated transport of the folic acid analog, methotrexate, in ehrlich ascites tumor cells

  BBA - Biomembranes. 1980;603(1):157-170.
  1

• 138.

  1980

  D.A. Gewirtz; J.K. Randolph; I.D. Goldman

  Potent bile salt and organic anion inhibition of methotrexate uptake and accumulation in the freshly isolated rat hepatocyte

  Cancer Research. 1980;40(6):1852-1857.
  4

• 139.

  1980

  J.C. White; R.A. Carchman; D.W. Fry; I.D. Goldman

  Relationship between membrane transport of methotrexate and endogenous cyclic adenosine 3':5'-monophosphate in the Ehrlich ascites tumor

  Cancer Research. 1980;40(7):2400-2404.
  0

• 140.

  1980

  D.A. Gewirtz; J.C. White; J.K. Randolph; I.D. Goldman

  Transport, binding, and polyglutamation of methotrexate in freshly isolated rat hepatocytes

  Cancer Research. 1980;40(3):573-578.
  14

• 141.

  1980

  D.W. Fry; J.C. White; I.D. Goldman

  Effects of 2,4-dinitrophenol and other metabolic inhibitors on the bidirectional carrier fluxes, net transport, and intracellular binding of methotrexate in Ehrlich ascites tumor cells

  Cancer Research. 1980;40(10):3669-3673.
  6

• 142.

  1979

  D. Bowen; R.B. Diasio; I.D. Goldman

  Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques

  Journal of Biological Chemistry. 1979;254(12):5333-5339.
  6

• 143.

  1979

  D.W. Fry; J.C. White; I.D. Goldman

  Alterations of the carrier-mediated transport of an anionic solute, methotrexate, by charged liposomes in Ehrlich ascites tumor cells

  Journal of Membrane Biology. 1979;50(2):123-140.
  2

• 144.

  1979

  B.T. Hill; B.D. Bailey; J.C. White; I.D. Goldman

  Characteristics of transport of 4-amino antifolates and folate compounds by two lines of L5178Y lymphoblasts, one with impaired transport of methotrexate

  Cancer Research. 1979;39(7 I):2440-2446.
  8

• 145.

  1979

  D.A. Gewirtz; J.C. White; J.K. Randolph; I.D. Goldman

  Formation of methotrexate polyglutamates in rat hepatocytes

  Cancer Research. 1979;39(8):2914-2918.
  1

• 146.

  1978

  J.C. White; B.D. Bailey; I.D. Goldman

  Lack of stereospecificity at carbon 6 of methyltetrahydrofolate transport in Ehrlich ascites tumor cells. Carrier-mediated transport of both stereoisomers.

  Journal of Biological Chemistry. 1978;253(1):242-245.
  7

• 147.

  1978

  D. Bowen; J.C. White; I.D. Goldman

  A basis for fluoropyrimidine induced antagonism to methotrexate in Ehrlich ascites tumor cells in vitro

  Cancer Research. 1978;38(1):219-222.
  1

• 148.

  1978

  D.W. Fry; J. Courtland White; I.D. Goldman

  Rapid separation of low molecular weight solutes from liposomes without dilution

  Analytical Biochemistry. 1978;90(2):809-815.
  176

• 149.

  1977

  I.David Goldman; Mary Jo Fyfe; Donnell Bowen; Sharon Loftfield; James A. Schafer

  The effect of microtubular inhibitors on transport of α-aminoisobutyric acid. Inhibition of uphill transport without changes in transmembrane gradients of Na⁺, K⁺, or H⁺

  BBA - Biomembranes. 1977;467(2):185-191.
  0

• 150.

  1977

  I.D. Goldman

  Effects of methotrexate on cellular metabolism: Some critical elements in the drug cell interaction

  Cancer Treatment Reports. 1977;61(4):549-558.
  2

• 151.

  1977

  I.D. Goldman

  Membrane transport of antifolates as a critical determinant of drug cytotoxicity.

  Advances in Experimental Medicine and Biology. 1977;84:85-113.
  1

• 152.

  1976

  I.D. Goldman; V. Gupta; J.C. White; S. Loftfield

  Exchangeable intracellular methotrexate levels in the presence and absence of vincristine at extracellular drug concentrations relevant to those achieved in high-dose methotrexate-folinic acid "rescue" protocols.

  Cancer Research. 1976;36(1):276-279.
  3

• 153.

  1976

  J.C. White; I.D. Goldman

  Mechanism of action of methotrexate. IV. Free intracellular methotrexate required to suppress dihydrofolate reduction to tetrahydrofolate by Ehrlich ascites tumor cells in vitro

  Molecular Pharmacology. 1976;12(5):711-719.
  19

• 154.

  1975

  D. Bowen; I.D. Goldman

  The relationship among transport, intracellular binding, and inhibition of RNA synthesis by actinomycin D in Ehrlich ascites tumor cells in vitro

  Cancer Research. 1975;35(11 I):3054-3060.
  1

• 155.

  1975

  M.J. Fyfe; S. Loftfield; I.D. Goldman

  A reduction in energy dependent amino acid transport by microtubular inhibitors in Ehrlich ascites tumor cells

  Journal of Cellular Physiology. 1975;86(2):I.
  1

• 156.

  1975

  J.C. Jennette; I.D. Goldman

  Inhibition of the membrane transport of folates by anions retained in uremia

  Journal of Laboratory and Clinical Medicine. 1975;86(5):834-843.
  36

• 157.

  1975

  J.C. White; S. Loftfield; I.D. Goldman

  The mechanism of action of methotrexate. III. Requirement of free intracellular methotrexate for maximal suppression of [¹⁴C]formate incorporation into nucleic acids and protein

  Molecular Pharmacology. 1975;11(3):287-297.
  6

• 158.

  1974

  I.D. Goldman; M.J. Fyfe

  The mechanism of action of methotrexate. II. Augmentation by vincristine of inhibition of deoxyribonucleic acid synthesis by methotrexate in Ehrlich ascites tumor cells

  Molecular Pharmacology. 1974;10(2):275-282.
  1

• 159.

  1974

  I.D. Goldman

  The mechanism of action of methotrexate. I. Interaction with a low affinity intracellular site required for maximum inhibition of deoxyribonucleic acid synthesis in L cell mouse fibroblasts

  Molecular Pharmacology. 1974;10(2):257-274.
  9

• 160.

  1973

  M.J. Fyfe; I.D. Goldman

  Characteristics of the vincristine induced augmentation of methotrexate uptake in Ehrlich ascites tumor cells

  Journal of Biological Chemistry. 1973;248(14):5067-5073.
  5

• 161.

  1972

  W.F. Bobzien 3rd.; I.D. Goldman

  The mechanism of folate transport in rabbit reticulocytes.

  Journal of Clinical Investigation. 1972;51(7):1688-1696.
  2

• 162.

  1971

  I.D. Goldman

  The characteristics of the membrane transport of amethopterin and the naturally occurring folates.

  Annals of the New York Academy of Sciences. 1971;186:400-422.
  82

• 163.

  1971

  I. David Goldman

  A model system for the study of heteroexchange diffusion: Methotrexate-folate interactions in L1210 leukemia and Ehrlich ascites tumor cells

  BBA - Biomembranes. 1971;223(3):624-634.
  19

• 164.

  1970

  D.L. Lilien; J.L. Spivak; I.D. Goldman

  Chromate transport in human leukocytes.

  Journal of Clinical Investigation. 1970;49(8):1551-1557.
  1

• 165.

  1970

  Norman S. Lichtenstein; I.David Goldman

  Riboflavin-methotrexate interactions. Photochemical reaction and competition for transport in the L1210 mouse leukemia cell

  Biochemical Pharmacology. 1970;19(4):1229-1239.
  2

• 166.

  1969

  Norman S. Lichtenstein; Vincent T. Oliverio; I.David Goldman

  Characteristics of folic acid transport in the L1210 leukemia cell

  BBA - Biomembranes. 1969;193(2):456-467.
  0

• 167.

  1969

  I.D. Goldman

  Transport energetics of the folic acid analogue, methotrexate, in L1210 leukemia cells. Enhanced accumulation by metabolic inhibitors.

  Journal of Biological Chemistry. 1969;244(14):3779-3785.
  35

• 168.

  1968

  I.D. Goldman; N.S. Lichtenstein; V.T. Oliverio

  Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell.

  Journal of Biological Chemistry. 1968;243(19):5007-5017.
  67