Hua Deng

Biochemistry

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Hua Deng

• Departments
  Biochemistry
  
  

718-430-2437

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Shan Ke; Meng-Chiao Ho; Nickolay Zhadin; Hua Deng; Robert Callender

  Investigation of catalytic loop structure, dynamics, and function relationship of Yersinia protein tyrosine phosphatase by temperature-jump relaxation spectroscopy and X-ray structural determination

  Journal of Physical Chemistry B. 2012;116(21):6166-6176.
  0

• 2.

  2011

  Logan D. Andrews; Hua Deng; Daniel Herschlag

  Isotope-edited FTIR of alkaline phosphatase resolves paradoxical ligand binding properties and suggests a role for ground-state destabilization

  Journal of the American Chemical Society. 2011;133(30):11621-11631.
  5

• 3.

  2011

  Hua Deng; Dung V. Vu; Keith Clinch; Ruel Desamero; R. Brian Dyer; Robert Callender

  Conformational heterogeneity within the Michaelis complex of lactate dehydrogenase

  Journal of Physical Chemistry B. 2011;115(23):7670-7678.
  4

• 4.

  2010

  Yong Zhang; Hua Deng; Vern L. Schramm

  Leaving group activation and pyrophosphate ionic state at the catalytic site of plasmodium falciparum orotate phosphoribosyltransferase

  Journal of the American Chemical Society. 2010;132(47):17023-17031.
  5

• 5.

  2010

  Hua Deng; Robert Callender; Vern L. Schramm; Charles Grubmeyer

  Pyrophosphate activation in hypoxanthine-guanine phosphoribosyltransferase with transition state analogue

  Biochemistry. 2010;49(12):2705-2714.
  3

• 6.

  2008

  Hua Deng; Scott Brewer; Dung M. Vu; Keith Clinch; Robert Callender; R. Brian Dyery

  On the pathway of forming enzymatically productive ligand-protein complexes in lactate dehydrogenase

  Biophysical Journal. 2008;95(2):804-813.
  11

• 7.

  2007

  Agnes Rinaldo-Matthis; Corin Wing; Mahmoud Ghanem; Hua Deng; Peng Wu; Arti Gupta; Peter C. Tyler; Gary B. Evans; Richard H. Furneaux; Steven C. Almo; et al.

  Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues

  Biochemistry. 2007;46(3):659-668.
  13

• 8.

  2006

  Hua Deng; Andrew S. Murkin; Vern L. Schramm

  Phosphate activation in the ground state of purine nucleoside phosphorylase

  Journal of the American Chemical Society. 2006;128(24):7765-7771.
  12

• 9.

  2004

  Hua Deng; Sean M. Cahill; José-Luis Abad; Andrzej Lewandowicz; Robert H. Callender; Vern L. Schramm; Roger A. Jones

  Active site contacts in the purine nucleoside phosphorylase-hypoxanthine complex by NMR and ab initio calculations

  Biochemistry. 2004;43(50):15966-15974.
  11

• 10.

  2004

  Hua Deng; Andrzej Lewandowicz; Vern L. Schramm; Robert Callender

  Activating the phosphate nucleophile at the catalytic site of purine nucleoside phosphorylase: A vibrational spectroscopic study

  Journal of the American Chemical Society. 2004;126(31):9516-9517.
  23

• 11.

  2004

  Hua Deng; Sean Cahill; Linda Kurz; Robert Callender

  The Assignment of Downfield Proton Resonances in an Enzyme Inhibitor Complex Using Time-Dependent Saturation Transferred NOEs

  Journal of the American Chemical Society. 2004;126(7):1952-1953.
  4

• 12.

  2004

  Hua Deng; Andrzej Lewandowicz; Sean M. Cahill; Richard H. Furneaux; Peter C. Tyler; Mark E. Girvin; Robert H. Callender; Vern L. Schramm

  Assignment of Downfield Proton Resonances in Purine Nucleoside Phosphorylase·Immucillin-H Complex by Saturation-Transferred NOEs

  Biochemistry. 2004;43(7):1980-1987.
  8

• 13.

  2002

  Hu Cheng; Ivana Nikolic-Hughes; Jianghua H. Wang; Hua Deng; Patrick J. O'Brien; Li Wu; Zhong-Yin Zhang; Daniel Herschlag; Robert Callender

  Environmental effects on phosphoryl group bonding probed by vibrational spectroscopy: Implications for understanding phosphoryl transfer and enzymatic catalysis

  Journal of the American Chemical Society. 2002;124(38):11295-11306.
  33

• 14.

  2002

  Hua Deng; Robert Callender; Jinge Zhu; Kiet T. Nguyen; Dehua Pei

  Determination of the ionization state and catalytic function of Glu-133 in peptide deformylase by difference FTIR spectroscopy

  Biochemistry. 2002;41(33):10563-10569.
  10

• 15.

  2002

  Hua Deng; Robert Callender; Zhonghui Huang; Zhong-Yin Zhang

  Is the PTPase - Vanadate complex a true transition state analogue?

  Biochemistry. 2002;41(18):5865-5872.
  14

• 16.

  2002

  Miriam Gulotta; Hua Deng; Hong Deng; R. Brian Dyer; Robert H. Callender

  Toward an understanding of the role of dynamics on enzymatic catalysis in lactate dehydrogenase

  Biochemistry. 2002;41(10):3353-3363.
  31

• 17.

  2002

  Ruel Z. B. Desamero; Hu Cheng; Sean Cahill; Mark Girvin; Hua Deng; Robert Callender; Parshuram Rath; Bruce Variano; John E. Smart

  Interactions of amidated acids with heparin

  Biopolymers - Biospectroscopy Section. 2002;67(1):41-48.
  0

• 18.

  2002

  Ruel Z. B. Desamero; Hu Cheng; Sean Cahill; Mark Girvin; Hua Deng; Robert Callender; Parshuram Rath; Bruce Variano; John E. Smart

  Physical properties of compounds promoting oral delivery of macromolecular drugs

  Biopolymers - Biospectroscopy Section. 2002;67(1):26-40.
  4

• 19.

  2001

  Hua Deng; Robert Callender; Elizabeth Howell

  Vibrational Structure of Dihydrofolate Bound to R67 Dihydrofolate Reductase

  Journal of Biological Chemistry. 2001;276(52):48956-48960.
  9

• 20.

  2001

  A.A. Sauve; I. Celic; J. Avalos; H. Deng; J.D. Boeke; V.L. Schramm

  Chemistry of gene silencing: The mechanism of NAD⁺-dependent deacetylation reactions

  Biochemistry. 2001;40(51):15456-15463.
  176

• 21.

  2001

  H. Cheng; S. Sukal; H. Deng; T.S. Leyh; R. Callender

  Vibrational structure of GDP and GTP bound to RAS: An isotope-edited FTIR study

  Biochemistry. 2001;40(13):4035-4043.
  36

• 22.

  2001

  H. Deng; N. Zhadin; R. Callender

  Dynamics of protein ligand binding on multiple time scales: NADH binding to lactate dehydrogenase

  Biochemistry. 2001;40(13):3767-3773.
  33

• 23.

  2000

  Hua Deng; Robert Callender; Glenn E. Dale

  A vibrational structure of 7,8-dihydrobiopterin bound to dihydroneopterin aldolase

  Journal of Biological Chemistry. 2000;275(39):30139-30143.
  10

• 24.

  1999

  Hua Deng; Robert Callender

  Raman spectroscopic studies of the structures, energetics, and bond distortions of substrates bound to enzymes

  Methods in Enzymology. 1999;308:176-201.
  13

• 25.

  1998

  Hua Deng; John F. Schindler; Kristine B. Berst; Bryce V. Plapp; Robert Callender

  A Raman spectroscopic characterization of bonding in the complex of horse liver alcohol dehydrogenase with NADH and N-cyclohexylformamide

  Biochemistry. 1998;37(40):14267-14278.
  18

• 26.

  1998

  J.H. Wang; D.G. Xiao; H. Deng; Martin R. Webb; Robert Callender

  Raman difference studies of GDP and GTP binding to c-Harvey ras

  Biochemistry. 1998;37(31):11106-11116.
  31

• 27.

  1998

  Hua Deng; Jianghua Wang; Robert H. Callender; Jean C. Grammer; Ralph G. Yount

  Raman difference spectroscopic studies of the myosin S1·MgADP·Vanadate complex

  Biochemistry. 1998;37(31):10972-10979.
  12

• 28.

  1998

  Hua Deng; Linda C. Kurz; Frederick B. Rudolph; Robert Callender

  Characterization of hydrogen bonding in the complex of adenosine deaminase with a transition state analogue: A Raman spectroscopic study

  Biochemistry. 1998;37(14):4968-4976.
  10

• 29.

  1998

  J.H. Wang; D.G. Xiao; H. Deng; R. Callender; M.R. Webb

  Vibrational study of phosphate modes in GDP and GTP and their interaction with magnesium in aqueous solution.

  Biospectroscopy. 1998;4(4):219-227.
  21

• 30.

  1997

  L. Huang; H. Deng; Y. Koutalos; T. Ebrey; M. Groesbeek; J. Lugtenburg; M. Tsuda; R.H. Callender

  A Resonance Raman Study of the C=C Stretch Modes in Bovine and Octopus Visual Pigments with Isotopically Labeled Retinal Chromophores

  Photochemistry and Photobiology. 1997;66(6):747-754.
  11

• 31.

  1996

  Hua Deng; Anita W.-Y. Chan; Carey K. Bagdassarian; Bernardo Estupiñán; Bruce Ganem; Robert H. Callender; Vern L. Schramm

  Trypanosomal nucleoside hydrolase. Resonance Raman spectroscopy of a transition-state inhibitor complex

  Biochemistry. 1996;35(19):6037-6047.
  25

• 32.

  1996

  L. Huang; H. Deng; G. Weng; Y. Koutalos; T. Ebrey; M. Groesbeek; J. Lugtenburg; M. Tsuda; R.H. Callender

  A resonance Raman study of the C=N configurations of octopus rhodopsin, bathorhodopsin, and isorhodopsin

  Biochemistry. 1996;35(26):8504-8510.
  9

• 33.

  1994

  H. Deng; L. Huang; R. Callender; T. Ebrey

  Evidence for a bound water molecule next to the retinal Schiff base in bacteriorhodopsin and rhodopsin: A resonance Raman study of the Schiff base hydrogen/deuterium exchange

  Biophysical Journal. 1994;66(4):1129-1136.
  62

• 34.

  1994

  Robert Callender; Hua Deng

  Nonresonance Raman difference spectroscopy: A general probe of protein structure, ligand binding, enzymatic catalysis, and the structures of other biomacromolecules

  Annual Review of Biophysics and Biomolecular Structure. 1994;23:215-245.
  74

• 35.

  1994

  H. Deng; J. Zheng; A. Clarke; J.J. Holbrook; R. Callender; J.W. Burgner II

  Source of catalysis in the lactate dehydrogenase system. Ground-state interactions in the enzyme·substrate complex

  Biochemistry. 1994;33(8):2297-2305.
  39

• 36.

  1993

  W.J. Ray Jr.; J.W. Burgner II; H. Deng; R. Callender

  Internal chemical bonding in solutions of simple phosphates and vanadates

  Biochemistry. 1993;32(48):12977-12983.
  22

• 37.

  1993

  H. Deng; W.J. Ray Jr.; J.W. Burgner II; R. Callender

  Comparison of vibrational frequencies of critical bonds in ground-state complexes and in a vanadate-based transition-state analog complex of muscle phosphoglucomutase. Mechanistic implications

  Biochemistry. 1993;32(48):12984-12992.
  17

• 38.

  1992

  Hua Deng; Jie Zheng; Donald Sloan; John Burgner; Robert Callender

  A vibrational analysis of the catalytically important C4-H bonds of NADH bound to lactate or malate dehydrogenase: Ground-state effects

  Biochemistry. 1992;31(21):5085-5092.
  23

• 39.

  1991

  H. Deng; D. Manor; G. Weng; P. Rath; Y. Koutalos; T. Ebrey; R. Gebhard; J. Lugtenburg; M. Tsuda; et al.

  A resonance Raman study of octopus bathorhodopsin with deuterium labeled retinal chromophores.

  Photochemistry and Photobiology. 1991;54(6):1001-1007.
  8

• 40.

  1991

  H. Deng; J. Burgner; R. Callender

  Raman spectroscopic studies of NAD coenzymes bound to malate dehydrogenases by difference techniques

  Biochemistry. 1991;30(36):8804-8811.
  13

• 41.

  1991

  H. Deng; D. Manor; G. Weng; P. Rath; Y. Koutalos; T. Ebrey; R. Gebhard; J. Lugtenburg; M. Tsuda; et al.

  Resonance Raman studies of the HOOP modes in octopus bathorhodopsin with deuterium-labeled retinal chromophores

  Biochemistry. 1991;30(18):4495-4502.
  16

• 42.

  1989

  H. Deng; J. Zheng; J. Burgner; R. Callender

  Molecular properties of pyruvate bound to lactate dehydrogenase: a Raman spectroscopic study.

  Proceedings of the National Academy of Sciences of the United States of America. 1989;86(12):4484-4488.
  16

• 43.

  1989

  Hua Deng; Jie Zheng; Donald Sloan; John Burgner; Robert Callender

  Classical Raman spectroscopic studies of NADH and NAD⁺ bound to lactate dehydrogenase by difference techniques

  Biochemistry. 1989;28(4):1525-1533.
  14

• 44.

  1987

  C. Pande; H. Deng; P. Rath; R.H. Callender; J. Schwemer

  Resonance raman spectroscopy of an ultraviolet-sensitive insect rhodopsin.

  Biochemistry. 1987;26(23):7426-7430.
  9

• 45.

  1987

  H. Deng; R.H. Callender

  A study of the schiff base mode in bovine rhodopsin and bathorhodopsin

  Biochemistry. 1987;26(23):7418-7426.
  20

• 46.

  1985

  H. Deng; C. Pande; R.H. Callender; T.G. Ebrey

  A detailed resonance Raman study of the M412 intermediate in the bacteriorhodopsin photocycle.

  Photochemistry and Photobiology. 1985;41(4):467-470.
  5