Publications of Jan Vijg - Albert Einstein College of Medicine

218 Publications

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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1.
2012

Tae Moon Kim; Jun Ho Ko; Lingchuan Hu; Sung-A Kim; Alexander J. R. Bishop; Jan Vijg; Cristina Montagna; Paul Hasty

RAD51 mutants cause replication defects and chromosomal instability
Molecular and Cellular Biology. 2012;32(18):3663-3680.

0
2.
2012

Vladimir N Anisimov; Andrzej Bartke; Nir Barzilai; Mikhail A Batin; Mikhail V Blagosklonny; Holly Brown-Borg; Yelena Budovskaya; Judith Campisi; Bertrand Friguet; Vadim Fraifeld; et al.

The second international conference "genetics of aging and longevity".
Aging. 2012;4(5):305-317.

0
3.
2012

Michael Gundry; Wenge Li; Shahina Bano Maqbool; Jan Vijg

Direct, genome-wide assessment of DNA mutations in single cells
Nucleic Acids Research. 2012;40(5):2032-2040.

4
4.
2012

Wenge Li; Jan Vijg

Measuring genome instability in aging - A mini-review
Gerontology. 2012;58(2):129-138.

3
5.
2012

Michael Gundry; Jan Vijg

Direct mutation analysis by high-throughput sequencing: From germline to low-abundant, somatic variants
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2012;729(1-2):1-15.

6
6.
2011

Ana M. Garcia; Robert N. Salomon; Alice Witsell; Justine Liepkalns; R Brent Calder; Moonsook Lee; Martha Lundell; Jan Vijg; Mitch McVey

Loss of the bloom syndrome helicase increases DNA ligase 4-independent genome rearrangements and tumorigenesis in aging Drosophila
Genome Biology. 2011;12(12).

2
7.
2011

Francesca Faggioli; Jan Vijg; Cristina Montagna

Chromosomal aneuploidy in the aging brain
Mechanisms of Ageing and Development. 2011;132(8-9):429-436.

5
8.
2010

Jan Vijg

Interview with Jan Vijg, Ph.D. [Interviewed by Vicki Glaser].
Rejuvenation research. 2010;13(5):619-622.

1
9.
2010

Yousin Suh; Jan Vijg

The long and short of fertility and longevity
Cell Metabolism. 2010;12(3):209-210.

2
10.
2010

Michael J. Rae; Robert N. Butler; Judith Campisi; Aubrey D. N. J. De Grey; Caleb E. Finch; Michael Gough; George M. Martin; Jan Vijg; Kevin M. Perrott; Barbara J. Logan

The demographic and biomedical case for late-life interventions in aging
Science Translational Medicine. 2010;2(40).

12
11.
2010

Mikhail V. Blagosklonny; Judy Campisi; David A. Sinclair; Andrzej Bartke; Maria A. Blasco; William M. Bonner; Vilhelm A. Bohr; Robert M. Brosh; Anne Brunet; Ronald A. DePinho; et al.

Impact papers on aging in 2009
Aging. 2010;2(3):111-121.

15
12.
2010

Ana Maria Garcia; R Brent Calder; Martijn E T Dollé; Martha Lundell; Pankaj Kapahi; Jan Vijg

Age- and temperature-dependent somatic mutation accumulation in Drosophila melanogaster.
PLoS genetics. 2010;6(5):e1000950.

8
13.
2010

Silvia Gravina; Jan Vijg

Epigenetic factors in aging and longevity
Pflugers Archiv European Journal of Physiology. 2010;459(2):247-258.

35
14.
2009

Pankaj Kapahi; Jan Vijg

Aging - Lost in translation?
New England Journal of Medicine. 2009;361(27):2669-2670.

5
15.
2009

Alexander Y. Maslov; Maya Metrikin; Jan Vijg

A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI
BioTechniques. 2009;47(4):847-854.

0
16.
2009

Alexander Y. Maslov; Jan Vijg

Genome instability, cancer and aging
Biochimica et Biophysica Acta - General Subjects. 2009;1790(10):963-969.

29
17.
2009

Jan Vijg

SNP'ing for longevity.
Aging. 2009;1(5):442-443.

2
18.
2009

Judith Campisi; Jan Vijg

Does damage to DNA and other macromolecules play a role in aging? If so, how?
Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2009;64(2):175-178.

32
19.
2009

Konstantin Khrapko; Jan Vijg

Mitochondrial DNA mutations and aging: devils in the details?
Trends in Genetics. 2009;25(2):91-98.

30
20.
2009

Hartmut Geiger; Schleimer David; Kalpana J Nattamai; Vijg Jan

Quantification of genomic mutations in murine hematopoietic cells.
Methods in molecular biology (Clifton, N.J.). 2009;506:423-436.

0
21.
2009

Ursula Edman; Ana Maria Garcia; Rita A. Busuttil; Dylan Sorensen; Martha Lundell; Pankaj Kapahi; Jan Vijg

Lifespan extension by dietary restriction is not linked to protection against somatic DNA damage in Drosophila melanogaster
Aging Cell. 2009;8(3):331-338.

20
22.
2009

Viviana I. Pérez; Holly Van Remmen; Alex Bokov; Charles J. Epstein; Jan Vijg; Arlan Richardson

The overexpression of major antioxidant enzymes does not extend the lifespan of mice
Aging Cell. 2009;8(1):73-75.

84
23.
2008

Guliang Wang; Steve Carbajal; Jan Vijg; John DiGiovanni; Karen M. Vasquez

DNA structure-induced genomic instability in vivo
Journal of the National Cancer Institute. 2008;100(24):1815-1817.

21
24.
2008

Jan Vijg; Alexander Y. Maslov; Yousin Suh

Aging: A Sirtuin Shake-Up?
Cell. 2008;135(5):797-798.

10
25.
2008

Valerie B. Holcomb; Francis Rodier; Yongjun Choi; Rita A. Busuttil; Hannes Vogel; Jan Vijg; Judith Campisi; Paul Hasty

Ku80 deletion suppresses spontaneous tumors and induces a p53-mediated DNA damage response
Cancer Research. 2008;68(22):9497-9502.

11
26.
2008

Valter D. Longo; Michael R. Lieber; Jan Vijg

Turning anti-ageing genes against cancer
Nature Reviews Molecular Cell Biology. 2008;9(11):903-910.

8
27.
2008

Rita A. Busuttil; Denise P. Muñoz; Ana Maria Garcia; Francis Rodier; Woo Ho Kim; Yousin Suh; Paul Hasty; Judith Campisi; Jan Vijg

Effect of Ku80 deficiency on mutation frequencies and spectra at a lacZ reporter locus in mouse tissues and cells
PLoS ONE. 2008;3(10).

4
28.
2008

Ana Maria Garcia; Rita A. Busuttil; R. Brent Calder; Martijn E.T. Dollé; Vivian Diaz; C. Alex McMahan; Andrzej Bartke; James Nelson; Robert Reddick; Jan Vijg

Effect of Ames dwarfism and caloric restriction on spontaneous DNA mutation frequency in different mouse tissues
Mechanisms of Ageing and Development. 2008;129(9):528-533.

18
29.
2008

Jan Vijg; Judith Campisi

Puzzles, promises and a cure for ageing
Nature. 2008;454(7208):1065-1071.

112
30.
2008

Rika Ouchida; Akiko Ukai; Hiromi Mori; Kiyoko Kawamura; Martijn E.T. Dollé; Masatoshi Tagawa; Akemi Sakamoto; Takeshi Tokuhisa; Tadashi Yokosuka; Takashi Saito; et al.

Genetic analysis reveals an intrinsic property of the germinal center B cells to generate A:T mutations
DNA Repair. 2008;7(8):1392-1398.

8
31.
2008

Jan Vijg

The role of DNA damage and repair in aging: New approaches to an old problem
Mechanisms of Ageing and Development. 2008;129(7-8):498-502.

18
32.
2008

Jung Yoon Park; Mi-Ook Cho; Shanique Leonard; Brent Calder; I. Saira Mian; Woo Ho Kim; Susan Wijnhoven; Harry van Steeg; James Mitchell; Gijsbertus T.J. van der Horst; et al.

Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd^TTD mice
PLoS ONE. 2008;3(6).

10
33.
2008

Rita A. Busuttil; Qingcong Lin; Peter J. Stambrook; Raju Kucherlapati; Jan Vijg

Mutation frequencies and spectra in DNA polymerase η-deficient mice
Cancer Research. 2008;68(7):2081-2084.

6
34.
2008

Joost P. M. Melis; Susan W. P. Wijnhoven; Rudolf B. Beems; Marianne Roodbergen; Jolanda Van Den Berg; Hojin Moon; Errol Friedberg; Gijsbertus T. J. Van Der Horst; Jan H. J. Hoeijmakers; Jan Vijg; et al.

Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes
Cancer Research. 2008;68(5):1347-1353.

23
35.
2008

George A. Garinis; Gijsbertus T.J. van der Horst; Jan Vijg; Jan H.J. Hoeijmakers

DNA damage and ageing: New-age ideas for an age-old problem
Nature Cell Biology. 2008;10(11):1241-1247.

76
36.
2007

Rita A. Busuttil; Ana Maria Garcia; Robert L. Reddick; Martijn E.T. Dollé; Robert B. Calder; James E. Nelson; Jan Vijg

Intra-organ variation in age-related mutation accumulation in the mouse
PLoS ONE. 2007;2(9).

20
37.
2007

Jan Vijg; Martijn E.T. Dollé

Genome instability: Cancer or aging?
Mechanisms of Ageing and Development. 2007;128(7-8):466-468.

7
38.
2007

R. Brent Calder; Rudolf B. Beems; Harry van Steeg; I. Saira Mian; Paul H.M. Lohman; Jan Vijg

MPHASYS: A mouse phenotype analysis system
BMC Bioinformatics. 2007;8.

4
39.
2007

Ana Maria Garcia; Anastasia Derventzi; Rita Busuttil; R. Brent Calder; Ernesto Perez; Linda Chadwell; Martijn E.T. Dollé; Martha Lundell; Jan Vijg

A model system for analyzing somatic mutations in Drosophila melanogaster
Nature Methods. 2007;4(5):401-403.

9
40.
2007

R. Busuttil; R. Bahar; J. Vijg

Genome dynamics and transcriptional deregulation in aging
Neuroscience. 2007;145(4):1341-1347.

17
41.
2007

Ana Maria Garcia; Rita A. Busuttil; Armando Rodriguez; Carlos Cabrera; Martha Lundell; Martijn E. T. Dolle; Jan Vijg

Detection and analysis of somatic mutations at a lacZ reporter locus in higher organisms: Application to Mus musculus and Drosophila melanogaster
Methods in Molecular Biology. 2007;371:267-287.

16
42.
2007

Konstantin Khrapko; Jan Vijg

Mitochondrial DNA mutations and aging: A case closed?
Nature Genetics. 2007;39(4):445-446.

24
43.
2006

Laura J. Niedernhofer; George A. Garinis; Anja Raams; Astrid S. Lalai; Andria Rasile Robinson; Esther Appeldoorn; Hanny Odijk; Roos Oostendorp; Anwaar Ahmad; Wibeke Van Leeuwen; et al.

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
Nature. 2006;444(7122):1038-1043.

246
44.
2006

Diane C. Cabelof; Yuji Ikeno; Abraham Nyska; Rita A. Busuttil; Njwen Anyangwe; Jan Vijg; Larry H. Matherly; James D. Tucker; Samuel H. Wilson; et al.

Haploinsufficiency in DNA polymerase β increases cancer risk with age and alters mortality rate
Cancer Research. 2006;66(15):7460-7465.

29
45.
2006

Rumana Bahar; Claudia H. Hartmann; Karl A. Rodriguez; Ashley D. Denny; Rita A. Busuttil; Martijn E. T. Dollé; R. Brent Calder; Gary B. Chisholm; Brad H. Pollock; Christoph A. Klein; et al.

Increased cell-to-cell variation in gene expression in ageing mouse heart
Nature. 2006;441(7096):1011-1014.

149
46.
2006

Konstantin Khrapko; Yevgenya Kraytsberg; Aubrey D.N.J. de Grey; Jan Vijg; Eric A. Schon

Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?
Aging Cell. 2006;5(3):279-282.

34
47.
2006

Toren Finkel; Jan Vijg; Jerry W. Shay

Time, tumours and telomeres: Meeting on cancer and aging
EMBO Reports. 2006;7(5):479-483.

1
48.
2006

Jan Vijg; Yousin Suh

Ageing: Chromatin unbound
Nature. 2006;440(7086):874-875.

7
49.
2006

Martijn E.T. Dollé; Rita A. Busuttil; Ana Maria Garcia; Susan Wijnhoven; Ellen van Drunen; Laura J. Niedernhofer; Gijsbertus van der Horst; Jan H.J. Hoeijmakers; Harry van Steeg; Jan Vijg

Increased genomic instability is not a prerequisite for shortened lifespan in DNA repair deficient mice
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2006;596(1-2 SPEC. ISS.):22-35.

47
50.
2006

James Mele; Holly Van Remmen; Jan Vijg; Arlan Richardson

Characterization of transgenic mice that overexpress both copper zinc superoxide dismutase and catalase
Antioxidants and Redox Signaling. 2006;8(3-4):628-638.

27
51.
2006

Yousin Suh; Jan Vijg

Maintaining genetic integrity in aging: A zero sum game
Antioxidants and Redox Signaling. 2006;8(3-4):559-571.

12
52.
2006

Rita A. Busuttil; Miguel Rubio; Martijn E.T. Dollé; Judith Campisi; Jan Vijg

Mutant frequencies and spectra depend on growth state and passage number in cells cultured from transgenic lacZ-plasmid reporter mice
DNA Repair. 2006;5(1):52-60.

16
53.
2005

Rita A. Busuttil; Ana Maria Garcia; Carlos Cabrera; Armando Rodriguez; Yousin Suh; Woo Ho Kim; Ting-Ting Huang; Jan Vijg

Organ-specific increase in mutation accumulation and apoptosis rate in CuZn-superoxide dismutase-deficient mice
Cancer Research. 2005;65(24):11271-11275.

29
54.
2005

Jan Vijg; Paul Hasty

Aging and p53: Getting it straight A commentary on a recent paper by Gentry and Venkatachalam
Aging Cell. 2005;4(6):331-333.

12
55.
2005

Susan W.P. Wijnhoven; Rudolf B. Beems; Marianne Roodbergen; Jolanda Van Den Berg; Paul H.M. Lohman; Karin Diderich; Gijsbertus T.J. Van Der Horst; Jan Vijg; Jan H.J. Hoeijmakers; Harry Van Steeg

Accelerated aging pathology in ad libitum fed Xpd^TTD mice is accompanied by features suggestive of caloric restriction
DNA Repair. 2005;4(11):1314-1324.

31
56.
2005

Yousin Suh; Jan Vijg

SNP discovery in associating genetic variation with human disease phenotypes
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2005;573(1-2):41-53.

75
57.
2005

Mark T. McCammon; John S. Gillette; Derek P. Thomas; Srinivas V. Ramaswamy; Edward A. Graviss; Barry N. Kreiswirth; Jan Vijg; Teresa N. Quitugua

Detection of rpoB mutations associated with rifampin resistance in Mycobacterium tuberculosis using denaturing gradient gel electrophoresis
Antimicrobial Agents and Chemotherapy. 2005;49(6):2200-2209.

30
58.
2005

Mark T. McCammon; John S. Gillette; Derek P. Thomas; Srinivas V. Ramaswamy; Ishmael I. Rosas; Edward A. Graviss; Jan Vijg; Teresa N. Quitugua

Detection by denaturing gradient gel electrophoresis of pncA mutations associated with pyrazinamide resistance in Mycobacterium tuberculosis isolates from the United States-Mexico border region
Antimicrobial Agents and Chemotherapy. 2005;49(6):2210-2217.

17
59.
2005

Armand M. Leroi; Andrzej Bartke; Giovanna De Benedictis; Claudio Franceschi; Anton Gartner; Eleftherios Gonos; Martin E. Feder; Toomas Kivisild; Sylvia Lee; Nesrin Kartal-Özer; et al.

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?
Mechanisms of Ageing and Development. 2005;126(3):421-429.

55
60.
2005

Jan Vijg; Yousin Suh

Genetics of longevity and aging
Annual Review of Medicine. 2005;56:193-212.

57
61.
2005

Jan Vijg; Rita A. Busuttil; Rumana Bahar; Martijn E.T. Dollé

Aging and genome maintenance
Annals of the New York Academy of Sciences. 2005;1055:35-47.

26
62.
2004

Jan Vijg

Impact of genome instability on transcription regulation of aging and senescence
Mechanisms of Ageing and Development. 2004;125(10-11 SPEC. ISS.):747-753.

22
63.
2004

Jan Vijg; R. Brent Calder

Transcripts of aging
Trends in Genetics. 2004;20(6):221-224.

12
64.
2004

Paul Hasty; Jan Vijg

Accelerating aging by mouse reverse genetics: A rational approach to understanding longevity
Aging Cell. 2004;3(2):55-65.

42
65.
2004

Paul Hasty; Jan Vijg

Rebuttal to Miller: 'Accelerated aging': A primrose path to insight?'
Aging Cell. 2004;3(2):67-69.

7
66.
2004

Xinlian Chen; Hanyu Liang; Holly Van Remmen; Jan Vijg; Arlan Richardson

Catalase transgenic mice: Characterization and sensitivity to oxidative stress
Archives of Biochemistry and Biophysics. 2004;422(2):197-210.

36
67.
2004

Rita A. Busuttil; Martijn Dollé; Judith Campisi; Jan Vijg

Genomic instability, aging, and cellular senescence
Annals of the New York Academy of Sciences. 2004;1019:245-255.

27
68.
2003

Rita A Busuttil; Miguel Rubio; Martijn E T Dollé; Judith Campisi; Jan Vijg

Oxygen accelerates the accumulation of mutations during the senescence and immortalization of murine cells in culture.
Aging cell. 2003;2(6):287-294.

85
69.
2003

Hong Yang; MingJian Shi; Arlan Richardson; Jan Vijg; ZhongMao Guo

Attenuation of leukocyte-endothelium interaction by antioxidant enzymes
Free Radical Biology and Medicine. 2003;35(3):266-276.

21
70.
2003

M. Bounpheng; S. McGrath; D. Macias; N. van Orsouw; Y. Suh; D. Rines; J. Vijg

Rapid, inexpensive scanning for all possible BRCA1 and BRCA2 gene sequence variants in a single assay: implications for genetic testing.
Journal of medical genetics. 2003;40(4):e33.

7
71.
2003

Esther M. Hoogervorst; Annemieke de Vries; Rudolf B. Beems; Conny Th.M. van Oostrom; Piet W. Wester; Joseph G. Vos; Wendy Bruins; Marianne Roodbergen; Flemming R. Cassee; Jan Vijg; et al.

Combined oral benzo[a]pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNA repair-deficient Xpa mice
Carcinogenesis. 2003;24(3):613-619.

14
72.
2003

Paul Hasty; Judith Campisi; Jan Hoeijmakers; Harry Van Steeg; Jan Vijg

Aging and genome maintenance: Lessons from the mouse?
Science. 2003;299(5611):1355-1359.

303
73.
2003

Xinlian Chen; James Mele; Heidi Giese; Holly Van Remmen; Martijn E.T. Dollé; Mark Steinhelper; Arlan Richardson; Jan Vijg

A strategy for the ubiquitous overexpression of human catalase and CuZn superoxide dismutase genes in transgenic mice
Mechanisms of Ageing and Development. 2003;124(2):219-227.

25
74.
2003

Hong Yang; MingJian Shi; Holly VanRemmen; XinLian Chen; Jan Vijg; Arlan Richardson; ZhongMao Guo

Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice
American Journal of Hypertension. 2003;16(1):1-5.

21
75.
2003

Jan Vijg; Yousin Suh

Functional genomics of ageing
Mechanisms of Ageing and Development. 2003;124(1):3-8.

14
76.
2002

Martijn E. T. Dollé; Jan Vijg

Genome dynamics in aging mice
Genome Research. 2002;12(11):1732-1738.

37
77.
2002

Paul Hasty; Jan Vijg

Genomic priorities in aging
Science. 2002;296(5571):1250-1251.

31
78.
2002

Jan Vijg; Martijn E.T. Dollé

Large genome rearrangements as a primary cause of aging
Mechanisms of Ageing and Development. 2002;123(8):907-915.

67
79.
2002

Ekaterina Nekhaeva; Natalya D. Bodyak; Yevgenya Kraytsberg; Sean B. McGrath; Nathalie J. Van Orsouw; Anna Pluzhnikov; Jeanne Y. Wei; Jan Vijg; Konstantin Khrapko

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues
Proceedings of the National Academy of Sciences of the United States of America. 2002;99(8):5521-5526.

107
80.
2002

Jan Vijg

On key lesions and all that: A tribute to Paul Lohman
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2002;499(2):121-134.

0
81.
2002

Heidi Giese; Wendy K Snyder; Conny Van Oostrom; Harry Van Steeg; Martijn E.T Dollé; Jan Vijg

Age-related mutation accumulation at a lacZ reporter locus in normal and tumor tissues of Trp53-deficient mice
Mutation Research - Genetic Toxicology and Environmental Mutagenesis. 2002;514(1-2):153-163.

20
82.
2002

Martijn E. T. Dollé; Wendy K. Snyder; David B. Dunson; Jan Vijg

Mutational fingerprints of aging
Nucleic Acids Research. 2002;30(2):545-549.

43
83.
2002

Jan Vijg; Nathalie Van Orsouw

Searching for genetic determinants of human aging and longevity: Opportunities and challenges
Mechanisms of Ageing and Development. 2002;123(2-3):195-205.

14
84.
2002

Yousin Suh; Kang-Ae Lee; Woo-Ho Kim; Bok-Ghee Han; Jan Vijg; Sang Chul Park

Aging alters the apoptotic response to genotoxic stress
Nature Medicine. 2002;8(1):3-4.

60
85.
2002

Irene L. Andrulis; Hoda Anton-Culver; Jeanne Beck; Betsy Bove; Jeff Boyd; Saundra Buys; Andrew K. Godwin; John L. Hopper; Frederick Li; et al.

Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations
Human Mutation. 2002;20(1):65-73.

50
86.
2001

C. Eng; L.C. Brody; T.M.U. Wagner; P. Devilee; J. Vijg; C. Szabo; S.V. Tavtigian; K.L. Nathanson; E. Ostrander; T.S. Frank; et al.

Interpreting epidemiological research: Blinded comparison of methods used to estimate the prevalence of inherited mutations in BRCA1
Journal of Medical Genetics. 2001;38(12):824-833.

121
87.
2001

Sean B. McGrath; Mangkey Bounpheng; Loyda Torres; Marco Calavetta; Charles B. Scott; Yousin Suh; David Rines; Nathalie Van Orsouw; Jan Vijg

High-speed, multicolor fluorescent two-dimensional gene scanning
Genomics. 2001;78(1-2):83-90.

9
88.
2001

Martijn E.T Dollé; Wendy K Snyder; Jan Vijg

Genotyping the Prop-1 mutation in Ames dwarf mice
Mechanisms of Ageing and Development. 2001;122(15):1915-1918.

4
89.
2001

Sandra L Martin; Craig L Hopkins; Anne Naumer; Martijn E.T Dollé; Jan Vijg

Mutation frequency and type during ageing in mouse seminiferous tubules
Mechanisms of Ageing and Development. 2001;122(12):1321-1331.

13
90.
2001

Sang Chul Park; K. Kitani; B.P. Yu; D.K. Ingram; A. Reznick; S. Goto; G.S. Roth; I. Zs.-Nagy; M. Meydani; J. Vijg; et al.

Perspectives in aging research in the new millennium
Annals of the New York Academy of Sciences. 2001;928:336-343.

0
91.
2001

Jan Vijg; Thomas Perls; Claudio Franceschi; Nathalie J. Van Orsouw

BRCA1 gene sequence variation in centenarians
Annals of the New York Academy of Sciences. 2001;928:85-96.

9
92.
2001

ZhongMao Guo; Holly Van Remmen; Hong Yang; XinLian Chen; James Mele; Jan Vijg; Charles J. Epstein; Ye-Shih Ho; Arlan Richardson

Changes in expression of antioxidant enzymes affect cell-mediated LDL oxidation and oxidized LDL-induced apoptosis in mouse aortic cells
Arteriosclerosis, Thrombosis, and Vascular Biology. 2001;21(7):1131-1138.

63
93.
2000

J. Bailey-Wilson; J. Baron; R. Cawthon; J.C. Christian; E.H. Corder; C. Franceschi; B. Kestenbaum; L. Kruglyak; D.S. Lauderdale; J. Lubitz; et al.

Genetic epidemiologic studies on age-specified traits
American Journal of Epidemiology. 2000;152(11):1003-1008.

17
94.
2000

Martijn E. T. Dollé; Wendy K. Snyder; Jan A. Gossen; Paul H. M. Lohman; Jan Vijg

Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine
Proceedings of the National Academy of Sciences of the United States of America. 2000;97(15):8403-8408.

116
95.
2000

Harry Van Steeg; Leon H.F. Mullenders; Jan Vijg

Mutagenesis and carcinogenesis in nucleotide excision repair-deficient XPA knock out mice
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2000;450(1-2):167-180.

34
96.
2000

Jen Jen Yeh; Kathryn L. Lunetta; Nathalie J. Van Orsouw; Francis D. Moore Jr.; George L. Mutter; Jan Vijg; Patricia Lm Dahia; Charis Eng

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours
Oncogene. 2000;19(16):2060-2066.

116
97.
2000

J. Vijg

The science of aging and the need for a mechanistic approach
Mechanisms of Ageing and Development. 2000;114(1):1-3.

5
98.
2000

J. Vijg

Somatic mutations and aging: A re-evaluation
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2000;447(1):117-135.

140
99.
2000

M.E. Dollé; H. Giese; H. van Steeg; J. Vijg

Mutation accumulation in vivo and the importance of genome stability in aging and cancer.
Results and problems in cell differentiation. 2000;29:165-180.

7
100.
2000

Samuel E Schriner; Charles E Ogburn; Annette C Smith; Terry G Newcomb; Warren C Ladiges; Martijn E.T Dollé; Jan Vijg; Ken-Ichiro Fukuchi; George M Martin

Levels of dna damage are unaltered in mice overexpressing human catalase in nuclei
Free Radical Biology and Medicine. 2000;29(7):664-673.

22
101.
1999

Konstantin Khrapko; Natalya Bodyak; William G. Thilly; Nathalie J. Van Orsouw; Xiaomin Zhang; Hilary A. Coller; Thomas T. Peris; Melissa Upton; Jan Vijg; et al.

Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions
Nucleic Acids Research. 1999;27(11):2434-2441.

97
102.
1999

Heidi Giese; Martijn E.T. Dollé; Aram Hezel; Harry Van Steeg; Jan Vijg

Accelerated accumulation of somatic mutations in mice deficient in the nucleotide excision repair gene XPA
Oncogene. 1999;18(5):1257-1260.

22
103.
1999

Nathalie J. Van Orsouw; Jan Vijg

Design and application of 2-D DGGE-based gene mutational scanning tests
Genetic Analysis - Biomolecular Engineering. 1999;14(5-6):205-213.

8
104.
1999

Jan Vijg

Genetics of aging - Sponsored by Cold Spring Harbor Laboratory, 2-5 April 1998
Biochimica et Biophysica Acta - Reviews on Cancer. 1999;1423(1):R1-R12.

2
105.
1999

Jan Vijg; Nathalie J. Van Orsouw

Two-dimensional gene scanning: Exploring human genetic variability
Electrophoresis. 1999;20(6):1239-1249.

17
106.
1999

Conny Th. M. Van Oostrom; Miranda Boeve; Jolanda Van Den Berg; Annemieke De Vries; Martijn E.T. Dollé; Rudolf B. Beems; Coen F. Van Kreijl; Jan Vijg; Harry Van Steeg

Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice
Environmental and Molecular Mutagenesis. 1999;34(2-3):124-130.

27
107.
1999

J. Vijg

Profiling aging by gene arrays
Mechanisms of Ageing and Development. 1999;112(1):1-4.

4
108.
1999

Martijn E. T. Dollé; Wendy K. Snyder; Nathalie J. Van Orsouw; Jan Vijg

Background mutations and polymorphisms in lacZ-plasmid transgenic mice
Environmental and Molecular Mutagenesis. 1999;34(2-3):112-120.

20
109.
1999

Nathalie J. Van Orsouw; Rahul K. Dhanda; Youssef Elhaji; Steven A. Narod; Frederick P. Li; Charis Eng; Jan Vijg

A highly accurate, low cost test for BRCA1 mutations
Journal of Medical Genetics. 1999;36(10):747-753.

29
110.
1999

Martijn E.T. Dollé; Hans-Jörg Martus; Maja Novak; Nathalie J. Van Orsouw; Jan Vijg

Characterization of color mutants in lacZ plasmid-based transgenic mice, as detected by positive selection
Mutagenesis. 1999;14(3):287-293.

25
111.
1998

Nathalie J. Van Orsouw; Xiaomin Zhang; Jeanne Wei; Donald R. Johns; Jan Vijg

Mutational scanning of mitochondrial DNA by two-dimensional electrophoresis
Genomics. 1998;52(1):27-36.

24
112.
1998

R. David Rines; Nathalie J. Van Orsouw; Iakovos Sigalas; Frederick P. Li; Charis Eng; Jan Vijg

Comprehensive mutational scanning of the p53 coding region by two-dimensional gene scanning
Carcinogenesis. 1998;19(6):979-984.

23
113.
1998

Jan Vijg; Harry Van Steeg

Transgenic assays for mutations and cancer: Current status and future perspectives
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1998;400(1-2):337-354.

19
114.
1998

Thomas T. Perls; Ellen Bubrick; Carrie G. Wager; Jan Vijg; Leonid Kruglyak

Siblings of centenarians live longer
Lancet. 1998;351(9115):1560.

120
115.
1998

Nathalie J. Van Orsouw; Rahul K. Dhanda; R. David Rines; Wendy M. Smith; Iakovos Sigalas; Charis Eng; Jan Vijg

Rapid design of denaturing gradient-based two-dimensional electrophoretic gene mutational scanning tests
Nucleic Acids Research. 1998;26(10):2398-2406.

27
116.
1998

R.K. Dhanda; N.J. Van Orsouw; Sigalas; C. Eng; J. Vijg

Critical factors in the performance and cost of two-dimensional gene scanning: RB1 as a model
BioTechniques. 1998;25(4):664-675.

10
117.
1998

W.M. Smith; N.J. Van Orsouw; E.A. Fox; R.D. Kolodner; J. Vijg; C. Eng

Accurate, high-throughput "snapshot" detection of hMLH1 mutations by two-dimensional DNA electrophoresis.
Genetic testing. 1998;2(1):43-53.

7
118.
1998

R.K. Dhanda; W.M. Smith; C.B. Scott; C. Eng; J. Vijg

A simple system for automated two-dimensional electrophoresis: applications to genetic testing.
Genetic testing. 1998;2(1):67-70.

10
119.
1998

S.L. Dabora; I. Sigalas; F. Hall; G. Eng; J. Vijg; D.J. Kwiatkowski

Comprehensive mutation analysis of TSC1 using two-dimensional DNA electrophoresis with DGGE
Annals of Human Genetics. 1998;62(6):491-504.

12
120.
1997

J. Vijg; M.E.T. Dolle; H.-J. Martus; M.E.T. Boerrigter

Erratum: Transgenic mouse models for studying mutations in vivo: Applications in aging research (Mechanisms of Ageing and Development (1997) 98 (189-202))
Mechanisms of Ageing and Development. 1997;99(3):257-271.

34
121.
1997

Annemieke De Vries; Martijn E.T. Dollé; José L.M. Broekhof; J.J. André Muller; E. Dinant Kroese; Coen F. Van Kreijl; Peter J.A. Capel; Jan Vijg; Harry Van Steeg

Induction of DNA adducts and mutations in spleen, liver and lung of XPA-deficient lacZ transgenic mice after oral treatment with benzo[a]pyrene: Correlation with tumour development
Carcinogenesis. 1997;18(12):2327-2332.

54
122.
1997

Jan Vijg; Martijn E.T. Dollé; Hans-Jörg Martus; Michael E.T.I. Boerrigter

Transgenic mouse models for studying mutations in vivo: Applications in aging research
Mechanisms of Ageing and Development. 1997;98(3):189-202.

10
123.
1997

Debbie J. Marsh; Stina Roth; Kathryn L. Lunetta; Akseli Hemminki; Patricia L. M. Dahia; Pertti Sistonen; Zimu Zheng; Stacey Caron; Nathalie J. Van Orsouw; Walter F. Bodmer; et al.

Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome
Cancer Research. 1997;57(22):5017-5021.

71
124.
1997

Charis Eng; Jan Vijg

Genetic testing: The problems and the promise
Nature Biotechnology. 1997;15(5):422-426.

84
125.
1997

Nathalie J. Van Orsouw; Daizong Li; Jan Vijg

Denaturing gradient gel electrophoresis (DGGE) increases resolution and informativity of Alu-directed inter-repeat PCR
Molecular and Cellular Probes. 1997;11(2):95-101.

10
126.
1997

Michaël E. T. I. Boerrigter; Jan Vijg

Sources of variability in mutant frequency determinations in different organs of lacZ plasmid-based transgenic mice: Experimental features and statistical analysis
Environmental and Molecular Mutagenesis. 1997;29(3):221-229.

14
127.
1997

Martijn E.T. Dollé; Heidi Giese; Craig L. Hopkins; Hans-Jörg Martus; Jeffrey M. Hausdorff; Jan Vijg

Rapid accumulation of genome rearrangements in liver but not in brain of old mice
Nature Genetics. 1997;17(4):431-434.

147
128.
1997

Anders Dupont Børglum; M. Nyegaard; A.B. Kvistgaard; E. Mullaart; A.G. Uitterlinden; J. Vijg; T.A. Kruse

Mapping of 34 minisatellite loci resolved by two-dimensional DNA typing
Cytogenetics and Cell Genetics. 1997;79(3-4):248-256.

0
129.
1996

Nathalie J. Van Orsouw; Daizong Li; Pieter Van Der Vlies; Hans Scheffer; Charis Eng; Charles H. C. M. Buys; Frederick P. Li; Jan Vijg

Mutational scanning of large genes by extensive PCR multiplexing and two-dimensional electrophoresis: Application to the RB1 gene
Human Molecular Genetics. 1996;5(6):755-761.

23
130.
1996

Daizong Li; Jan Vijg

Multiplex co-amplification of 24 retinoblastoma gene exons after pre-amplification by long-distance PCR
Nucleic Acids Research. 1996;24(3):538-539.

26
131.
1996

Martijn E.T. Dollé; Hans-Jörg Martus; Jan A. Gossen; Michael E.T.I. Boerrigter; Jan Vijg

Evaluation of a plasmid-based transgenic mouse model for detecting in vivo mutations
Mutagenesis. 1996;11(1):111-118.

57
132.
1996

Ying Wu; Robert M.W. Hofstra; Hans Scheffer; André G. Uitterlinden; Erik Mullaart; Charles H.C.M. Buys; Jan Vijg

Comprehensive and accurate mutation scanning of the CFTR gene by two- dimensional DNA electrophoresis
Human Mutation. 1996;8(2):160-167.

22
133.
1995

Jan Vijg

Two-dimensional DNA typing - A cost-effective way of analyzing complex mixtures of DNA fragments for sequence variations
Molecular Biotechnology. 1995;4(3):275-295.

6
134.
1995

E. Mullaart; A.M. Verwest; A.D. Borglum; A.G. Uitterlinden; G.J. Te Meerman; T.A. Kruse; J. Vijg

Two-dimensional DNA typing of human pedigrees: Spot pattern characterization and segregation
Genomics. 1995;29(3):641-646.

3
135.
1995

A.D. Borglum; E. Mullaart; A.B. Kvistgaard; A.G. Uitterlinden; J. Vijg; T.A. Kruse

Two-dimensional DNA typing as a genetic marker system in humans
Cytogenetics and Cell Genetics. 1995;71(3):260-265.

1
136.
1995

J. Vijg; J.Y. Wei

Understanding the biology of aging: The key to prevention and therapy
Journal of the American Geriatrics Society. 1995;43(4):426-434.

27
137.
1995

S. Xiao; D. Li; J.M. Corson; J. Vijg; J.A. Fletcher

Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma
Cancer Research. 1995;55(14):2968-2971.

69
138.
1995

Michaël E. T. I. Boerrigter; Jeanne Y. Wei; Jan Vijg

Induction and repair of benzo[a]pyrene-DNA adducts in C57BL/6 and BALB/c mice: Association with aging and longevity
Mechanisms of Ageing and Development. 1995;82(1):31-50.

22
139.
1995

J.A. Gossen; H.-J. Martus; J.Y. Wei; J. Vijg

Spontaneous and X-ray-induced deletion mutations in a LacZ plasmid-based transgenic mouse model
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1995;331(1):89-97.

59
140.
1995

H.-J. Jorg-Martus; M.E.T. Dolle; J.A. Gossen; M.E.T.I. Boerrigter; J. Vijg

Use of transgenic mouse models for studying somatic mutations in aging
Mutation Research - DNAging Genetic Instability and Aging. 1995;338(1-6):203-213.

27
141.
1995

S. Xiao; D. Li; J. Vijg; D.J. Sugarbaker; J.M. Corson; J.A. Fletcher

Codeletion of p15 and p16 in primary malignant mesothelioma
Oncogene. 1995;11(3):511-515.

91
142.
1995

M.E.T.I. Boerrigter; M.E.T. Dolle; H.-J. Martus; J.A. Gossen; J. Vijg

Plasmid-based transgenic mouse model for studying in vivo mutations
Nature. 1995;377(6550):657-659.

101
143.
1995

J. Vijg

Detecting individual genetic variation
Bio/Technology. 1995;13(2):137-139.

6
144.
1994

Jan Vijg; Ying Wu; AndréG. Uitterlinden; Erik Mullaart

Two-dimensional DNA electrophoresis in mutation detection
Mutation Research Regular Papers. 1994;308(2):205-214.

4
145.
1994

A.M. Verwest; W.J.F. de Leeuw; A.C. Molijn; T.I. Andersen; A.-L. Börresen; E. Mullaart; A.G. Uitterlinden; J. Vijg

Genome scanning of breast cancers by two-dimensional DNA typing
British Journal of Cancer. 1994;69(1):84-92.

11
146.
1994

J.A. Gossen; W.J.F. De Leeuw; J. Vijg

LacZ transgenic mouse models: Their application in genetic toxicology
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1994;307(2):451-459.

29
147.
1993

E. Mullaart; G.J. de Vos; G.J. te Meerman; A.G. Uitterlinden; J. Vijg

Parallel genome analysis by two-dimensional DNA typing.
Nature. 1993;365(6445):469-471.

10
148.
1993

G.J. Trommelen; J.H. Den Daas; J. Vijg; A.G. Uitterlinden

DNA profiling of cattle using micro- and minisatellite core probes.
Animal Genetics. 1993;24(4):235-241.

4
149.
1993

G.J. Trommelen; N.H. Den Daas; J. Vijg; A.G. Uitterlinden

Identity and paternity testing of cattle: application of a deoxyribonucleic acid profiling protocol.
Journal of dairy science. 1993;76(5):1403-1411.

4
150.
1993

J.A. Gossen; W.J.F. de Leeuw; A.Q. Bakker; J. Vijg

DNA sequence analysis of spontaneous mutations at a LacZ transgene integrated on the mouse X chromosome
Mutagenesis. 1993;8(3):243-247.

19
151.
1993

E. Hovig; E. Mullaart; A.-L. Borresen; A.G. Uitterlinden; J. Vijg

Genome scanning of human breast carcinomas using micro- and minisatellite core probes
Genomics. 1993;17(1):66-75.

6
152.
1993

G.J. Te Meerman; E. Mullaart; M.A. Van der Meulen; J.H.G. Den Daas; B. Morolli; A.G. Uitterlinden; J. Vijg

Linkage analysis by two-dimensional DNA typing
American Journal of Human Genetics. 1993;53(6):1289-1297.

10
153.
1993

A.J.W. Hoorn; L.L. Custer; B.C. Myhr; D. Brusick; J. Gossen; J. Vijg

Detection of chemical mutagens using Muta® mouse: A transgenic mouse model
Mutagenesis. 1993;8(1):7-10.

55
154.
1993

M.E.T.I. Boerrigter; R. Franceschi; E. Arrigoni-Martelli; J.Y. Wei; J. Vijg

The effect of L-carnitine and acetyl-L-carnitine on the disappearance of DNA single-strand breaks in human peripheral blood lymphocytes
Carcinogenesis. 1993;14(10):2131-2136.

25
155.
1993

J. Gossen; J. Vijg

Transgenic mice as model systems for studying gene mutations in vivo
Trends in Genetics. 1993;9(1):27-31.

38
156.
1993

M.E.T.I. Boerrigter; Y. Yin; J. Vijg; J.Y. Wei

DNA repair in congenic mice: Possible influence of a chromosome 4 genetic region on the rate of benzo[a]pyrene-induced DNA adduct removal
Journals of Gerontology. 1993;48(1):B11-B16.

2
157.
1993

J. Vijg; J.A. Gossen

Somatic mutations and cellular aging
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 1993;104(3):429-437.

14
158.
1993

J.A. Gossen; J. Vijg

A selective system for lacZ^- phage using a galactose-sensitive E. coli host
BioTechniques. 1993;14(3):326+320.

45
159.
1993

J.A. Gossen; W.J.F. De Leeuw; A.C. Molijn; J. Vijg

Plasmid rescue from transgenic mouse DNA using LacI repressor protein conjugated to magnetic beads
BioTechniques. 1993;14(4):624-629.

31
160.
1992

M.E.T.I. Boerrigter; J. Vijg

Single-strand break disappearance in quiescent and phytohemagglutinin-stimulated human peripheral blood lymphocytes exposed to a single low dose of γ-radiation
International Journal of Radiation Biology. 1992;61(1):95-101.

13
161.
1992

W. Huppes; C.J.A. De Groot; R.H. Ostendorf; J.G.J. Bauman; J.A. Gossen; V. Smit; J. Vijg; C.D. Dijkstra

Detection of migrated allogeneic oligodendrocytes throughout the central nervous system of the galactocerebrosidase-defficient twitcher mouse
Journal of Neurocytology. 1992;21(2):129-136.

6
162.
1992

M.E.T.I. Boerrigter; J.Y. Wei; J. Vijg

DNA repair and Alzheimer's disease
Journals of Gerontology. 1992;47(6):B177-B184.

34
163.
1992

J.A. Gossen; A.C. Molijn; G.R. Douglas; J. Vijg

Application of galactose-sensitive e.Coli strains as selective hosts for LacZ^- plasmids
Nucleic Acids Research. 1992;20(12):3254.

79
164.
1992

J. Vijg; W.J.F. De Leeuw; G.R. Douglas; J.A. Gossen

Transgenic mice and age-related mutations
Annals of the New York Academy of Sciences. 1992;663:26-35.

1
165.
1992

P.E. Slagboom; J. Vijg

The dynamics of genome organization and expression during the aging process
Annals of the New York Academy of Sciences. 1992;673:58-69.

5
166.
1991

P.E. Slagboom; E. Mullaart; S. Droog; J. Vijg

Somatic mutations and cellular aging: two-dimensional DNA typing of rat fibroblast clones.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1991;256(2-6):311-321.

1
167.
1991

A.G. Uitterlinden; E.P. Slagboom; E. Mullaart; I. Meulenbelt; J. Vijg

Genome scanning by two-dimensional DNA typing: The use of repetitive DNA sequences for rapid mapping of genetic traits
Electrophoresis. 1991;12(2):119-134.

5
168.
1991

J.A. Gossen; W.J. de Leeuw; M. Verwest; J. Vijg

Analysis of spontaneous and induced mutation frequencies in transgenic mice using a lambda shuttle vector system.
Progress in clinical and biological research. 1991;372:313-318.

1
169.
1991

J. Vijg; J.A. Gossen; W.J.F. De Leeuw; E. Mullaart; P.E. Slagboom; A.G. Uitterlinden

DNA processing, aging, and cancer: The impact of new technology
Annals of the New York Academy of Sciences. 1991;621:53-65.

0
170.
1991

M.E.T.I. Boerrigter; J. Vijg

Induction and disappearance of DNA single-strand breaks in human B and T lymphocytes after exposure to ethylnitrosourea
Mutation Research - DNA Repair. 1991;255(1):49-55.

8
171.
1991

M.E.T.I. Boerrigter; C.M. Van Duijn; E. Mullaart; P. Eikelenboom; C.M.A. Van der Togt; D.L. Knook; A. Hofman; J. Vijg

Decreased DNA repair capacity in familial, but not in sporadic Alzheimer's disease
Neurobiology of Aging. 1991;12(4):367-370.

6
172.
1991

J.A. Gossen; W.J.F. De Leeuw; A. Verwest; P.H.M. Lohman; J. Vijg

High somatic mutation frequencies in a LacZ transgene integrated on the mouse X-chromosome
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1991;250(1-2):423-429.

25
173.
1991

P.E. Slagboom; A.G. Uitterlinden; J. Vijg

Methylation status of cKi-ras and MHC genes in rat pituitary glands during aging and tumorigenesis
Aging - Clinical and Experimental Research. 1991;3(2):141-146.

1
174.
1991

J. Vijg

New methods for the detection of genetic variation.
Annali dell'Istituto Superiore di Sanita. 1991;27(1):123-126.

0
175.
1991

M.E.T.I. Boerrigter; E. Mullaart; F. Berends; J. Vijg

Induction and disappearance of DNA strand breaks and/or alkali-labile sites in human lymphocytes exposed to N-ethyl-N-nitrosourea
Carcinogenesis. 1991;12(1):77-82.

3
176.
1991

M.E.T.I. Boerrigter; E. Mullaart; J. Vijg

Induction and disappearance of DNA strand breaks in human peripheral blood lymphocytes and fibroblasts treated with methyl methanesulfonate
Experimental Cell Research. 1991;192(1):61-66.

9
177.
1991

A.G. Uitterlinden; J. Vijg

Denaturing gradient gel electrophoretic analysis of minisatellite alleles
Electrophoresis. 1991;12(1):12-16.

6
178.
1990

J. Vijg

Extension of life: the apotheosis of the molecular biomedical sciences?
Tijdschrift voor Gerontologie en Geriatrie. 1990;21(5):199-204.

0
179.
1990

P.Eline Slagboom; Wiljo J.F. De Leeuw; Jan Vijg

Messenger RNA levels and methlation patterns of GAPDH and β-actin genes in rat liver, spleen and brain in relation to aging
Mechanisms of Ageing and Development. 1990;53(3):243-257.

36
180.
1990

A.G. Uitterlinden; J. Vijg

Denaturing gradient gel electrophoretic analysis of the human cHa-ras1 proto-oncogene.
Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society. 1990;1(4):175-179.

3
181.
1990

A.T. Natarajan; S.E. Vlasblom; A. Manca; P.H. Lohman; J.A. Gossen; J. Vijg; F. Beermann; E. Hummler; I. Hansmann

Transgenic mouse--an in vivo system for detection of aneugens.
Progress in clinical and biological research. 1990;340 B:295-299.

1
182.
1990

J. Vijg

Searching for the molecular basis of aging: The need for life extension models
Aging - Clinical and Experimental Research. 1990;2(3):227-229.

5
183.
1990

J. Vijg; J. Papaconstantinou

Aging and longevity genes: Strategies for identifying DNA sequences controlling life span
Journals of Gerontology. 1990;45(5):B179-B182.

7
184.
1990

M.E.T.I. Boerrigter; E. Mullaart; G.P. Van der Schans; J. Vijg

Illusory DNA breaks in quiescent lymphocytes?
Experimental Cell Research. 1990;188(1):1.

1
185.
1990

J.A. Gossen; J. Vijg

Transgenic mice as a model to study gene mutations: application as a short-term mutagenicity assay.
Progress in clinical and biological research. 1990;340 A:347-354.

4
186.
1990

E. Mullaart; P.H.M. Lohman; F. Berends; J. Vijg

DNA damage metabolism and aging
Mutation Research - DNAging Genetic Instability and Aging. 1990;237(5-6):189-210.

87
187.
1990

P.E. Slagboom; W.J.F. De Leeuw; J. Vijg

mRNA levels and methylation patterns of the tyrosine aminotransferase gene in aging inbred rats
FEBS Letters. 1990;269(1):128-130.

0
188.
1990

J. Vijg

DNA sequence changes in aging: How frequent, how important?
Aging - Clinical and Experimental Research. 1990;2(2):105-123.

12
189.
1990

E. Mullaart; M.E.T.I. Boerrigter; G.J. Boer; J. Vijg

Spontaneous DNA breaks in the rat brain during development and aging
Mutation Research. 1990;237(1):9-15.

19
190.
1990

E. Mullaart; M.E.T.I. Boerrigter; R. Ravid; D.F. Swaab; J. Vijg

Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients
Neurobiology of Aging. 1990;11(3):169-173.

83
191.
1989

C. Franceschi; R.B. Setlow; T. Sugimura; J. Vijg

About an old problem, new approaches, a new section.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1989;219(2):83-85.

0
192.
1989

J. Vijg

Molecular gerontology needs coordination.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1989;219(2):87-88.

0
193.
1989

A.G. Uitterlinden; P.E. Slagboom; T.E. Johnson; J. Vijg

The Caenorhabditis elegans genome contains monomorphic minisatellites and simple sequences
Nucleic Acids Research. 1989;17(23):9527-9530.

7
194.
1989

P.E. Slagboom; J. Vijg

Genetic instability and aging: Theories, facts, and future perspectives
Genome. 1989;31(1):373-385.

10
195.
1989

J.A. Gossen; W.J.F. De Leeuw; C.H.T. Tan; E.C. Zwarthoff; F. Berends; P.H.M. Lohman; D.L. Knook; J. Vijg

Efficient rescue of integrated shuttle vectors from transgenic mice: A model for studying mutations in vivo
Proceedings of the National Academy of Sciences of the United States of America. 1989;86(20):7971-7975.

284
196.
1989

J.J.P. Gille; C.G.M. Van Berkel; E. Mullaart; J. Vijg; H. Joenje

Effects of lethal exposure to hyperoxia and to hydrogen peroxide on NAD(H) and ATP pools in Chinese hamster ovary cells
Mutation Research. 1989;214(1):89-96.

14
197.
1989

E. Mullaart; L. Roza; P.H.M. Lohman; J. Vijg

The removal of UV-induced pyrimidine dimers from DNA of rat skin cells in vitro and in vivo in relation to aging
Mechanisms of Ageing and Development. 1989;47(3):253-264.

8
198.
1989

A.G. Uitterlinden; P.E. Slagboom; D.L. Knook; J. Vijg

Two-dimensional DNA fingerprinting of human individuals
Proceedings of the National Academy of Sciences of the United States of America. 1989;86(8):2742-2746.

16
199.
1989

J.J.P. Gille; E. Mullaart; J. Vijg; A.L. Leyva; F. Arwert; H. Joenje

Chromosomal instability in an oxygen-tolerant variant of Chinese hamster ovary cells
Mutation Research. 1989;219(1):17-28.

14
200.
1989

E. Mullaart; M.E.T.I. Boerrigter; P.H.M. Lohman; J. Vijg

Age-related induction and disappearance of carcinogen-DNA-adducts in livers of rats exposed to low levels of 2-acetylaminofluorene
Chemico-Biological Interactions. 1989;69(4):373-384.

4
201.
1989

M.E.T.I. Boerrigter; E. Mullaart; G.P. Van Der Schans; J. Vijg

Quiescent human peripheral blood lymphocytes do not contain a sizable amount of preexistent DNA single-strand breaks
Experimental Cell Research. 1989;180(2):569-573.

7
202.
1989

E. Mullaart; M. Buytenhek; A. Brouwer; P.H.M. Lohman; J. Vijg

Genotoxic effects of intragastrically administered benzo[a]pyrene in rat liver and intestinal cells
Carcinogenesis. 1989;10(2):393-395.

4
203.
1989

W.J.F. De Leeuw; P.E. Slagboom; J. Vijg

Quantitative comparison of mRNA levels in mammalian tissues: 28S ribosomal RNA level as an accurate internal control
Nucleic Acids Research. 1989;17(23):10137-10138.

78
204.
1988

C. Franceschi; R.B. Setlow; T. Sugimura; J. Vijg

About an old problem, new approaches, a new section.
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 1988:3-5.

0
205.
1988

E. Mullaart; P.H.M. Lohman; J. Vijg

Differences in pyrimidine dimer removal between rat skin cells in vitro and in vivo
Journal of Investigative Dermatology. 1988;90(3):346-349.

5
206.
1988

E. Mullaart; M.E.T.I. Boerrigter; A. Brouwer; F. Berends; J. Vijg

Age-dependent accumulation of alkali-labile sites in DNA of post-mitotic but not in that of mitotic rat liver cells
Mechanisms of Ageing and Development. 1988;45(1):41-49.

14
207.
1988

J.A. Gossen; J. Vijg

E. coli C: A convenient host strain for rescue of highly methylated DNA
Nucleic Acids Research. 1988;16(19):9343.

8
208.
1987

C. Gravekamp; L.P. van Den Bulck; J. Vijg; R.J. van de Griend; R.L. Bolhuis

c-myc Gene expression and interleukin-2 receptor levels in cloned human CD2⁺,CD3⁺ and CD2⁺,CD3^- lymphocytes
Natural Immunity and Cell Growth Regulation. 1987;6(1):28-36.

2
209.
1987

J. Vijg; D.L. Knook

DNA repair in relation to the aging process
Journal of the American Geriatrics Society. 1987;35(6):532-541.

7
210.
1987

J. Vijg; A.G. Uitterlinden

A search for DNA alterations in the aging mammalian genome: An experimental strategy
Mechanisms of Ageing and Development. 1987;41(1-2):47-63.

4
211.
1987

P.H.M. Lohman; J. Vijg; A.G. Uitterlinden; P. Slagboom; J.A. Gossen; F. Berends

DNA methods for detecting and analyzing mutations in vivo
Mutation Research. 1987;181(2):227-234.

2
212.
1986

J. Vijg; E. Mullaart; F. Berends; P.H.M. Lohman; D.L. Knook

UV-induced DNA excision repair in rat fibroblasts during immortalization and terminal differentiation in vitro
Experimental Cell Research. 1986;167(2):517-530.

0
213.
1986

J. Vijg; E. Mullaart; L. Roza; R.A. Baan; P.H.M. Lohman

Immunochemical detection of DNA in alkaline sucrose gradient fractions
Journal of Immunological Methods. 1986;91(1):53-58.

0
214.
1986

J. Vijg; L. Roza; E. Mullaart; P.H. Lohman

Species specificity in the induction and repair of DNA damage.
Progress in clinical and biological research. 1986;209 A:179-187.

0
215.
1985

A.G. Uitterlinden; J. Vijg; M.J. Giphart; D.L. Knook

Variation in restriction fragment length and methylation pattern of rat MHC class I genes
Experimental and Clinical Immunogenetics. 1985;2(4):215-222.

0
216.
1985

J. Vijg; E. Mullaart; P.H.M. Lohman; D.L. Knook

UV-induced unscheduled DNA synthesis in fibroblasts of aging inbred rats
Mutation Research. 1985;146(2):197-204.

7
217.
1984

J. Vijg; E. Mullaart; G.P. van der Schans; P.H.M. Lohman; D.L. Knook

Kinetics of ultraviolet induced DNA excision repair in rat and human fibroblasts
Mutation Research DNA Repair Reports. 1984;132(3-4):129-138.

14
218.
1983

G.H. Schaap; A. Verkerk; J. Vijg; J.F. Jongkind

Flow sorting in the study of cell-cell interaction
Cytometry. 1983;3(6):408-413.

0

Jan Vijg Genetics

Jan Vijg

Jan Vijg
Genetics