Margaret Kielian

Cell Biology

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Margaret Kielian

• Departments
  Cell Biology
  
  

718-430-3638

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Catherine Y. Liu; Margaret Kielian

  Identification of a specific region in the E1 fusion protein involved in zinc inhibition of semliki forest virus fusion

  Journal of Virology. 2012;86(7):3588-3594.
  0

• 2.

  2011

  Gleyder Roman-Sosa; Margaret Kielian

  The interaction of alphavirus E1 protein with exogenous domain III defines stages in virus-membrane fusion

  Journal of Virology. 2011;85(23):12271-12279.
  1

• 3.

  2011

  Katie M. Stiles; Margaret Kielian

  Alphavirus entry: NRAMP leads the way

  Cell Host and Microbe. 2011;10(2):92-93.
  1

• 4.

  2011

  Yan Zheng; Claudia Saspacute;nchez-San Martín; Zhao-ling Qin; Margaret Kielian

  The domain I-domain III linker plays an important role in the fusogenic conformational change of the alphavirus membrane fusion protein

  Journal of Virology. 2011;85(13):6334-6342.
  5

• 5.

  2010

  Margaret Kielian

  Structural biology: An alphavirus puzzle solved

  Nature. 2010;468(7324):645-646.
  4

• 6.

  2010

  Catherine Y. Liu; Christen Besanceney; Yifan Song; Margaret Kielian

  Pseudorevertants of a semliki forest virus fusion-blocking mutation reveal a critical interchain interaction in the core trimer

  Journal of Virology. 2010;84(22):11624-11633.
  3

• 7.

  2010

  Aihua Zheng; Mahadevaiah Umashankar; Margaret Kielian

  In Vitro and In vivo studies identify important features of dengue virus pr-E protein interactions

  PLoS Pathogens. 2010;6(10).
  12

• 8.

  2010

  Maofu Liao; Claudia Sánchez-San Martín; Aihua Zheng; Margaret Kielian

  In Vitro reconstitution reveals key intermediate states of trimer formation by the dengue virus membrane fusion protein

  Journal of Virology. 2010;84(11):5730-5740.
  12

• 9.

  2009

  Catherine Y. Liu; Margaret Kielian

  E1 mutants identify a critical region in the trimer interface of the Semliki Forest virus fusion protein

  Journal of Virology. 2009;83(21):11298-11306.
  7

• 10.

  2009

  Claudia Sánchez-San Martín; Catherine Y. Liu; Margaret Kielian

  Dealing with low pH: entry and exit of alphaviruses and flaviviruses

  Trends in Microbiology. 2009;17(11):514-521.
  31

• 11.

  2009

  Zhao-Ling Qin; Yan Zheng; Margaret Kielian

  Role of conserved histidine residues in the low-pH dependence of the Semliki Forest virus fusion protein

  Journal of Virology. 2009;83(9):4670-4677.
  26

• 12.

  2008

  Claudia Sánchez-San Martín; Hernando Sosa; Margaret Kielian

  A Stable Prefusion Intermediate of the Alphavirus Fusion Protein Reveals Critical Features of Class II Membrane Fusion

  Cell Host and Microbe. 2008;4(6):600-608.
  15

• 13.

  2008

  M. Umashankar; Claudia Sánchez-San Martín; Maofu Liao; Brigid Reilly; Alice Guo; Gwen Taylor; Margaret Kielian

  Differential cholesterol binding by class II fusion proteins determines membrane fusion properties

  Journal of Virology. 2008;82(18):9245-9253.
  30

• 14.

  2007

  Gwen M. Taylor; Phyllis I. Hanson; Margaret Kielian

  Ubiquitin depletion and dominant-negative VPS4 inhibit rhabdovirus budding without affecting alphavirus budding

  Journal of Virology. 2007;81(24):13631-13639.
  27

• 15.

  2007

  Ruben M. Markosyan; Margaret Kielian; Fredric S. Cohen

  Fusion induced by a class II viral fusion protein, Semliki Forest virus E1, is dependent on the voltage of the target cell

  Journal of Virology. 2007;81(20):11218-11225.
  7

• 16.

  2006

  Maofu Liao; Margaret Kielian

  Functions of the stem region of the Semliki Forest virus fusion protein during virus fusion and assembly

  Journal of Virology. 2006;80(22):11362-11369.
  12

• 17.

  2006

  Maofu Liao; Margaret Kielian

  Site-directed antibodies against the stem region reveal low pH-induced conformational changes of the Semliki Forest virus fusion protein

  Journal of Virology. 2006;80(19):9599-9607.
  9

• 18.

  2006

  Chantal Chanel-Vos; Margaret Kielian

  Second-site revertants of a Semliki Forest Virus fusion-block mutation reveal the dynamics of a class II membrane fusion protein

  Journal of Virology. 2006;80(12):6115-6122.
  17

• 19.

  2006

  Margaret Kielian

  Class II virus membrane fusion proteins

  Virology. 2006;344(1):38-47.
  91

• 20.

  2006

  Margaret Kielian; Félix A. Rey

  Virus membrane-fusion proteins: More than one way to make a hairpin

  Nature Reviews Microbiology. 2006;4(1):67-76.
  220

• 21.

  2005

  Maofu Liao; Margaret Kielian

  Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion

  Journal of Cell Biology. 2005;171(1):111-120.
  56

• 22.

  2005

  Xinyong Zhang; Margaret Kielian

  An interaction site of the envelope proteins of Semliki Forest virus that is preserved after proteolytic activation

  Virology. 2005;337(2):344-352.
  5

• 23.

  2005

  Maofu Liao; Margaret Kielian

  The conserved glycine residues in the transmembrane domain of the Semliki Forest virus fusion protein are not required for assembly and fusion

  Virology. 2005;332(1):430-437.
  7

• 24.

  2004

  Chantal Chanel-Vos; Margaret Kielian

  A conserved histidine in the ij loop of the Semliki Forest virus E1 protein plays an important role in membrane fusion

  Journal of Virology. 2004;78(24):13543-13552.
  35

• 25.

  2004

  Xinyong Zhang; Margaret Kielian

  Mutations that promote furin-independent growth of Semliki Forest virus affect p62-E1 interactions and membrane fusion

  Virology. 2004;327(2):287-296.
  11

• 26.

  2004

  Don L. Gibbons; Anna Ahn; Maofu Liao; Lena Hammar; R. Holland Cheng; Margaret Kielian

  Multistep Regulation of Membrane Insertion of the Fusion Peptide of Semliki Forest Virus

  Journal of Virology. 2004;78(7):3312-3318.
  31

• 27.

  2004

  Don L. Gibbons; Brigid Reilly; Anna Ahn; Marie-Christine Vaney; Armelle Vigouroux; Felix A. Rey; Margaret Kielian

  Purification and Crystallization Reveal Two Types of Interactions of the Fusion Protein Homotrimer of Semliki Forest Virus

  Journal of Virology. 2004;78(7):3514-3523.
  20

• 28.

  2004

  Don L. Gibbons; Marie-Christine Vaney; Alain Roussel; Armelle Vigouroux; Brigid Reilly; Jean Lepault; Margaret Kielian; Félix A. Rey

  Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus

  Nature. 2004;427(6972):320-325.
  187

• 29.

  2003

  Don L. Gibbons; Inge Erk; Brigid Reilly; Jorge Navaza; Margaret Kielian; Félix A. Rey; Jean Lepault

  Visualization of the target-membrane-inserted fusion protein of semliki forest virus by combined electron microscopy and crystallography

  Cell. 2003;114(5):573-583.
  64

• 30.

  2003

  Xinyong Zhang; Martin Fugère; Robert Day; Margaret Kielian

  Furin processing and proteolytic activation of Semliki Forest virus

  Journal of Virology. 2003;77(5):2981-2989.
  41

• 31.

  2002

  Prodyot K. Chatterjee; Christina H. Eng; Margaret Kielian

  Novel mutations that control the sphingolipid and cholesterol dependence of the semliki forest virus fusion protein

  Journal of Virology. 2002;76(24):12712-12722.
  27

• 32.

  2002

  Andrey V. Samsonov; Prodyot K. Chatterjee; Vladimir I. Razinkov; Christina H. Eng; Margaret Kielian; Fredric S. Cohen

  Effects of membrane potential and sphingolipid structures on fusion of Semliki Forest virus

  Journal of Virology. 2002;76(24):12691-12702.
  18

• 33.

  2002

  Anna Ahn; Don L. Gibbons; Margaret Kielian

  The fusion peptide of Semliki Forest virus associates with sterol-rich membrane domains

  Journal of Virology. 2002;76(7):3267-3275.
  85

• 34.

  2002

  Don L. Gibbons; Margaret Kielian

  Molecular dissection of the Semliki Forest virus homotrimer reveals two functionally distinct regions of the fusion protein

  Journal of Virology. 2002;76(3):1194-1205.
  24

• 35.

  2002

  Margaret Kielian

  Structural surprises from the flaviviruses and alphaviruses

  Molecular Cell. 2002;9(3):454-456.
  12

• 36.

  2001

  Swati Ghosh Shome; Margaret Kielian

  Differential roles of two conserved glycine residues in the fusion peptide of Semliki Forest Virus

  Virology. 2001;279(1):146-160.
  10

• 37.

  2001

  Y.E. Lu; C.H. Eng; S.G. Shome; M. Kielian

  In vivo generation and characterization of a soluble form of the Semliki Forest virus fusion protein

  Journal of Virology. 2001;75(17):8329-8339.
  13

• 38.

  2000

  M. Kielian; P.K. Chatterjee; D.L. Gibbons; Y.E. Lu

  Specific roles for lipids in virus fusion and exit. Examples from the alphaviruses.

  Sub-cellular biochemistry. 2000;34:409-455.
  54

• 39.

  2000

  Y.E. Lu; M. Kielian

  Semliki forest virus budding: Assay, mechanisms, and cholesterol requirement

  Journal of Virology. 2000;74(17):7708-7719.
  36

• 40.

  2000

  D.L. Gibbons; A. Ahn; P.K. Chatterjee; M. Kielian

  Formation and characterization of the trimeric form of the fusion protein of Semliki Forest virus

  Journal of Virology. 2000;74(17):7772-7780.
  46

• 41.

  2000

  Prodyot K. Chatterjee; Malini Vashishtha; Margaret Kielian

  Biochemical consequences of a mutation that controls the cholesterol dependence of Semliki Forest virus fusion

  Journal of Virology. 2000;74(4):1623-1631.
  33

• 42.

  1999

  Anna Ahn; Matthew R. Klimjack; Prodyot K. Chatterjee; Margaret Kielian

  An epitope of the Semliki Forest virus fusion protein exposed during virus-membrane fusion

  Journal of Virology. 1999;73(12):10029-10039.
  23

• 43.

  1999

  Anna Ahn; Randal J. Schoepp; David Sternberg; Margaret Kielian

  Growth and stability of a cholesterol-independent Semliki Forest virus mutant in mosquitoes

  Virology. 1999;262(2):452-456.
  10

• 44.

  1999

  Yanping E. Lu; Todd Cassese; Margaret Kielian

  The cholesterol requirement for sindbis virus entry and exit and characterization of a spike protein region involved in cholesterol dependence

  Journal of Virology. 1999;73(5):4272-4278.
  89

• 45.

  1998

  Sallie Glomb-Reinmund; Margaret Kielian

  The role of low pH and disulfide shuffling in the entry and fusion of Semliki Forest virus and Sindbis virus

  Virology. 1998;248(2):372-381.
  47

• 46.

  1998

  Sallie Glomb-Reinmund; Margaret Kielian

  fus-1, a pH shift mutant of Semliki Forest virus, acts by altering spike subunit interactions via a mutation in the E2 subunit

  Journal of Virology. 1998;72(5):4281-4287.
  29

• 47.

  1998

  Malini Vashishtha; Thomas Phalen; Marianne T. Marquardt; Jae S. Ryu; Alice C. Ng; Margaret Kielian

  A single point mutation controls the cholesterol dependence of Semliki Forest virus entry and exit

  Journal of Cell Biology. 1998;140(1):91-99.
  86

• 48.

  1997

  Natalie L. Jacobs; Biree Andemariam; Kathryn W. Underwood; Krishnanchali Panchalingam; David Sternberg; Margaret Kielian; Laura Liscum

  Analysis of a Chinese hamster ovary cell mutant with defective mobilization of cholesterol from the plasma membrane to the endoplasmic reticulum

  Journal of Lipid Research. 1997;38(10):1973-1987.
  22

• 49.

  1997

  Melissa M. Rolls; Marianne T. Marquardt; Margaret Kielian; Carolyn E. Machamer

  Cholesterol-independent targeting of Golgi membrane proteins in insect cells

  Molecular Biology of the Cell. 1997;8(11):2111-2118.
  12

• 50.

  1996

  Marianne T. Marquardt; Margaret Kielian

  Cholesterol-depleted cells that are relatively permissive for Semliki Forest virus infection

  Virology. 1996;224(1):198-205.
  17

• 51.

  1996

  Margaret Kielian; Matthew R. Klimjack; Swati Ghosh; Wayne A. Duffus

  Mechanisms of mutations inhibiting fusion and infection by Semliki Forest virus

  Journal of Cell Biology. 1996;134(4):863-872.
  75

• 52.

  1996

  Jayme L. Martys; Christina Wjasow; Dawn M. Gangi; Margaret C. Kielian; Timothy E. McGraw; Jonathan M. Backer

  Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells: Differential effects on endocytosis and lysosomal sorting

  Journal of Biological Chemistry. 1996;271(18):10953-10962.
  106

• 53.

  1995

  W.A. Duffus; P. Levy-Mintz; M.R. Klimjack; M. Kielian

  Mutations in the putative fusion peptide of Semliki Forest virus affect spike protein oligomerization and virus assembly

  Journal of Virology. 1995;69(4):2471-2479.
  41

• 54.

  1995

  M. Kielian

  Membrane fusion and the alphavirus life cycle

  Advances in Virus Research. 1995;45:113-151.
  94

• 55.

  1994

  Matthew R. Klimjack; Susan Jeffrey; Margaret Kielian

  Membrane and protein interactions of a soluble form of the Semliki Forest virus fusion protein

  Journal of Virology. 1994;68(11):6940-6946.
  69

• 56.

  1993

  Jessica Justman; Matthew R. Klimjack; Margaret Kielian

  Role of spike protein conformational changes in fusion of Semliki Forest virus

  Journal of Virology. 1993;67(12):7597-7607.
  36

• 57.

  1993

  M.T. Marquardt; T. Phalen; M. Kielian

  Cholesterol is required in the exit pathway of Semliki Forest virus

  Journal of Cell Biology. 1993;123(1):57-65.
  33

• 58.

  1991

  P. Levy-Mintz; M. Kielian

  Mutagenesis of the putative fusion domain of the semliki forest virus spike protein

  Journal of Virology. 1991;65(8):4292-4300.
  75

• 59.

  1991

  T. Phalen; M. Kielian

  Cholesterol is required for infection by Semliki Forest virus

  Journal of Cell Biology. 1991;112(4):615-623.
  97

• 60.

  1991

  S.K. Jain; S. DeCandido; M. Kielian

  Processing of the p62 envelope precursor protein of semliki forest virus

  Journal of Biological Chemistry. 1991;266(9):5756-5761.
  17

• 61.

  1990

  M. Kielian; S. Jungerwirth; K. Ullrich Sayad; S. DeCandido

  Biosynthesis, maturation, and acid activation of the Semliki Forest virus fusion protein

  Journal of Virology. 1990;64(10):4614-4624.
  46

• 62.

  1990

  M. Kielian; S. Jungerwirth

  Mechanisms of Enveloped virus entry into cells

  Molecular Biology and Medicine. 1990;7(1):17-31.
  58

• 63.

  1989

  S. Schmid; R. Fuchs; M. Kielian; A. Helenius; I. Mellman

  Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants

  Journal of Cell Biology. 1989;108(4):1291-1300.
  62

• 64.

  1986

  M.C. Kielian; M. Marsh; A. Helenius

  Kinetics of endosome acidification detected by mutant and wild-type Semliki Forest virus.

  EMBO Journal. 1986;5(12):3103-3109.
  36

• 65.

  1986

  M. Kielian

  Assay of phagosome-lysosome fusion

  Methods in Enzymology. 1986;Vol. 132:257-267.
  5

• 66.

  1985

  A. Helenius; M. Kielian; J. Wellsteed; I. Mellman; G. Rudnick

  Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells

  Journal of Biological Chemistry. 1985;260(9):5691-5697.
  14

• 67.

  1985

  M. Kielian; A. Helenius

  pH-Iinduced alterations in the fusogenic spike protein of Semliki Forest virus

  Journal of Cell Biology. 1985;101(6):2284-2291.
  58

• 68.

  1984

  M.C. Kielian; A. Helenius

  Role of cholesterol in fusion of Semliki Forest virus with membranes

  Journal of Virology. 1984;52(1):281-283.
  84

• 69.

  1984

  M.C. Kielian; S. Keranen; L. Kaariainen; A. Helenius

  Membrane fusion mutants of Semliki Forest virus

  Journal of Cell Biology. 1984;98(1):139-145.
  40

• 70.

  1984

  M. Marsh; M.C. Kielian; A. Helenius

  Semliki forest virus entry and the endocytic pathway

  Biochemical Society Transactions. 1984;12(6):981-983.
  12

• 71.

  1983

  J. White; M. Kielian; A. Helenius

  Membrane fusion proteins of enveloped animal viruses.

  Quarterly Reviews of Biophysics. 1983;16(2):151-195.
  96

• 72.

  1982

  M.C. Kielian; Z.A. Cohn

  Intralysosomal accumulation of polyanions. II. Polyanion internalization and its influence on lysosomal pH and membrane fluidity

  Journal of Cell Biology. 1982;93(3):875-882.
  19

• 73.

  1982

  M.C. Kielian; R.M. Steinman; Z.A. Cohn

  Intralysosomal accumulation of polyanions. I. Fusion of pinocytic and phagocytic vacuoles with secondary lysosomes

  Journal of Cell Biology. 1982;93(3):866-874.
  14

• 74.

  1981

  M.C. Kielian; Z.A. Cohn

  Modulation of phagosome-lysosome fusion in mouse macrophages

  Journal of Experimental Medicine. 1981;153(4):1015-1020.
  6

• 75.

  1981

  M.C. Kielian; Z.A. Cohn

  Phorbol myristate acetate stimulates phagosome-lysosome fusion in mouse macrophages

  Journal of Experimental Medicine. 1981;154(1):101-111.
  6

• 76.

  1980

  M.C. Kielian; Z.A. Cohn

  Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages

  Journal of Cell Biology. 1980;85(3):754-765.
  24

• 77.

  1977

  M.C. Kielian; C.F. Beyer; W.E. Bowers

  Cell-cell interactions in blast transformation of rat lymphocytes by neuraminidase and galactose oxidase

  Experimental Cell Research. 1977;109(1):211-221.
  0