Oral Health and Diagnostic Sciences

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Bupivacaine injection during midurethral sling and postoperative pain: A randomized controlled trial

Gena C. Dunivan; Brent A. Parnell; AnnaMarie Connolly; Mary L. Jannelli; Bethany Jablonski Horton; Elizabeth J. Geller (Profiled Author: Brent A Parnell)

International Urogynecology Journal and Pelvic Floor Dysfunction. 2011;22(4):433-438.

Introduction: and hypothesis The aim of this study was to investigate the impact of retropubic injection of 0.125% bupivacaine during midurethral sling placement on postoperative pain. Methods: A randomized, double-blind trial of 42 women undergoing midurethral sling for stress incontinence was conducted. The intervention group received an injection of 0.125% bupivacaine in the retropubic space prior to midurethral sling placement, while the control group received no injection. Pain scores were recorded via a 10-cm visual analog scale at 2, 6, and 24 h postoperatively. Results: Pain scores were lower in the bupivacaine group compared to the control group at 2 h (1.9 versus 2.6, p= 0.05). Mean pain scores were similar at all other time points (all p>0.45). Participants in both groups used similar amounts of pain medication in the hospital, except that patients in the bupivacaine group used more PO nonsteroidal anti-inflammatory drugs (p=0.047). Conclusions: Retropubic injection of 0.125% bupivacaine at the time of midurethral sling placement decreases shortterm postoperative pain. © The International Urogynecological Association 2011.

PMID: 21318442    

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