Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Successful management of an infant with a giant hemangioma of the retroperitoneum and Kasabach-Merritt Syndrome with α-interferon
Journal of Pediatric Surgery. 1993;28(10):1356-1359.Abstract
Giant vascular neoplasms in neonates generally require aggressive medical or surgical therapy for treatment of complications. Steroids, chemotherapy, embolization, radiation, and surgery have all been used with short-term beneficial and sometimes unknown long-term side effects. A new modality of treatment, α-interferon, has recently been described. The majority of hemangiomas in children involtute by 8 years of age. Occasionally, hemangiomas can endanger vital structures and are associated with a consumption coagulopathy and thrombocytopenia (Kasabach-Merritt Syndrome). These hemangiomas occasionally do not respond to steroids, radiation therapy, cytotoxic drugs, or embolization. The mortality rates approach 50% in nonresponders. Alphainterferon has been used in these children with life-threatening complications of hemangiomas with relief of symptoms. This case illustrates the potential use of α-interferon in the management of giant hemangiomas in children. This emerging form of biological therapy avoids the risks of radiation therapy, embolization, and surgery with only minimal side effects. © 1993 W.B. Saunders Company. All rights reserved.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Richard R. Ricketts; Robyn M. Hatley; Brian J. Corden; Herman Sabio; Charles G. HowellAnnals of Surgery. 1994;219(6):605-614.
H.A. Heck Jr.; C.L. Lutcher; D.G. FallsSouthern Medical Journal. 1994;87(8):789-793.
Elizabeth Barrows; Barbara KrajClinical laboratory science : journal of the American Society for Medical Technology. 2010;23(4):201-204.
Appears in this Document