Publications of Ahmad R. Safa - IUSM ReSEARCH Connect

111 Publications

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111 Publications From Scopus

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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1.
2012

A.R. Safa

c-FLIP, a master anti-apoptotic regulator
Experimental Oncology. 2012;34(3):176-184.

3
2.
2011

Ahmad R. Safa; Karen E. Pollok

Targeting the anti-apoptotic protein c-FLIP for cancer therapy
Cancers. 2011;3(2):1639-1671.

12
3.
2010

Khadijeh Bijangi-Vishehsaraei; Mohammad Reza Saadatzadeh; Su Huang; Michael P. Murphy; Ahmad R. Safa

4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells
Molecular and Cellular Biochemistry. 2010;342(1-2):133-142.

4
4.
2010

Soo-Jung Park; Khadijeh Bijangi-Vishehsaraei; Ahmad R. Safa

Selective TRAIL-triggered apoptosis due to overexpression of TRAIL death receptor 5 (DR5) in P-glycoprotein-bearing multidrug resistant CEM/VBL1000 human leukemia cells
International Journal of Biochemistry and Molecular Biology. 2010;1(1):90-100.

7
5.
2009

Joshua L. Fischer; M.A. Suresh Kumar; Travis W. Day; Tabitha M. Hardy; Shari Hamilton; Cynthia Besch-Williford; Ahmad R. Safa; Karen E. Pollok; Martin L. Smith

The Xpc gene markedly affects cell survival in mouse bone marrow
Mutagenesis. 2009;24(4):309-316.

3
6.
2009

Fei Shen; Barbara J. Bailey; Shaoyou Chu; Aimee K. Bence; Xinjian Xue; Priscilla Erickson; Ahmad R. Safa; William T. Beck; Leonard C. Erickson

Dynamic assessment of mitoxantrone resistance and modulation of multidrug resistance by valspodar (PSC833) in multidrug resistance human cancer cells
Journal of Pharmacology and Experimental Therapeutics. 2009;330(2):423-429.

10
7.
2009

Travis W. Day; Ahmad R. Safa

RNA interference in cancer: Targeting the anti-apoptotic protein c-FLIP for drug discovery
Mini-Reviews in Medicinal Chemistry. 2009;9(6):741-748.

9
8.
2009

Travis W. Day; Ching-Huang Wu; Ahmad R. Safa

Etoposide induces protein kinase Cδ- and caspase-3-dependent apoptosis in neuroblastoma cancer cells
Molecular Pharmacology. 2009;76(3):632-640.

13
9.
2009

Travis W. Day; Anthony L. Sinn; Su Huang; Karen E. Pollok; George E. Sandusky; Ahmad R. Safa

C-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells
Anticancer Research. 2009;29(10):3883-3886.

3
10.
2009

Su Huang; Travis W. Day; Mi-Ran Choi; Ahmad R. Safa

Human β-galactoside α-2,3-sialyltransferase (ST3Gal III) attenuated Taxol-induced apoptosis in ovarian cancer cells by downregulating caspase-8 activity
Molecular and Cellular Biochemistry. 2009;331(1-2):81-88.

3
11.
2008

Ahmad R. Safa; Travis W. Day; Ching-Huang Wu

Cellular FLICE-like inhibitory protein (C-FLIP): A novel target for cancer therapy
Current Cancer Drug Targets. 2008;8(1):37-46.

66
12.
2008

Mi-Ran Choi; Farhad Najafi; Ahmad R. Safa; Hannes C.A. Drexler

Analysis of changes in the proteome of HL-60 promyeloid leukemia cells induced by the proteasome inhibitor PSI
Biochemical Pharmacology. 2008;75(12):2276-2288.

4
13.
2008

Ching-Huang Wu; Ching-Hai Kao; Ahmad R. Safa

TRAIL recombinant adenovirus triggers robust apoptosis in multidrug-resistant HL-60/Vinc cells preferentially through death receptor DR5
Human Gene Therapy. 2008;19(7):731-743.

6
14.
2008

Travis W. Day; Su Huang; Ahmad R. Safa

c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells
Biochemical Pharmacology. 2008;76(12):1694-1704.

21
15.
2007

Xiaoling Zhong; Ahmad R. Safa

Phosphorylation of RNA helicase a by DNA-dependent protein kinase is indispensable for expression of the MDR1 gene product P-glycoprotein in multidrag-resistant human leukemia cells
Biochemistry. 2007;46(19):5766-5775.

7
16.
2006

Travis W. Day; Farhad Najafi; Ching-Huang Wu; Ahmad R. Safa

Cellular FLICE-like inhibitory protein (c-FLIP): A novel target for Taxol-induced apoptosis
Biochemical Pharmacology. 2006;71(11):1551-1561.

31
17.
2006

Soo-Jung Park; Ching-Huang Wu; Mi-Ran Choi; Farhad Najafi; Armaghan Emami; Ahmad R. Safa

P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5
Biochemical Pharmacology. 2006;72(3):293-307.

17
18.
2004

Ahmad R. Safa

Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators
Current Medicinal Chemistry - Anti-Cancer Agents. 2004;4(1):1-17.

36
19.
2004

Soo-Jung Park; Ching-Haung Wu; Ahmad R. Safa

A P-glycoprotein- and MRP1-independent Doxorubicin-resistant Variant of the MCF-7 Breast Cancer Cell Line with Defects in Caspase-6, -7, -8, -9 and -10 Activation Pathways
Anticancer Research. 2004;24(1):123-131.

15
20.
2004

Xiaoling Zhong; Ahmad R. Safa

RNA Helicase A in the MEF1 Transcription Factor Complex Up-regulates the MDR1 Gene in Multidrug-resistant Cancer Cells
Journal of Biological Chemistry. 2004;279(17):17134-17141.

21
21.
2004

Soo-Jung Park; Ching-Haung Wu; John D. Gordon; Xiaoling Zhong; Armaghan Emami; Ahmad R. Safa

Taxol induces caspase-10-dependent apoptosis
Journal of Biological Chemistry. 2004;279(49):51057-51067.

112
22.
2003

John Gordon; Ching-Huang Wu; Mojgan Rastegar; Ahmad R. Safa

β₂-microglobulin induces caspase-dependent apoptosis in the CCRF-HSB-2 human leukemia cell line independently of the caspase-3, -8 and -9 pathways but through increased reactive oxygen species
International Journal of Cancer. 2003;103(3):316-327.

18
23.
2002

Caio Max S Rocha Lima; Swan-Swan Leong; Carol A Sherman; Joshua A Perkel; Terri Putman; Ahmad R Safa; Mark R Green

Irinotecan and gemcitabine in patients with solid tumors: phase I trial.
Oncology (Williston Park, N.Y.). 2002;16(5 Suppl 5):[d]19-24.

1
24.
2002

Ching-Huang Wu; John Gordon; Mojgan Rastegar; Besim Ogretmen; Ahmad R. Safa

Proteinase-3, a serine protease which mediates doxorubicin-induced apoptosis in the HL-60 leukemia cell line, is downregulated in its doxorubicin-resistant variant
Oncogene. 2002;21(33):5160-5174.

11
25.
2002

Ching-Huang Wu; John D. Gordon; Xiaoling Zhong; Ahmad R. Safa

Mechanism of β₂- microglobulin-induced apoptosis in the K562 leukemia cell line, defective in major histocompatibility class 1
Anticancer Research. 2002;22(5):2613-2621.

3
26.
2001

Ching-Huang Wu; Mojgan Rastegar; John Gordon; Ahmad R. Safa

β₂-microglobulin induces apoptosis in HL-60 human leukemia cell line and its multidrug resistant variants overexpressing MRP1 but lacking Bax or overexpressing P-glycoprotein
Oncogene. 2001;20(48):7006-7020.

16
27.
2000

R.A. Safa

Erratum: Photoaffinity analogs for multidrug resistance-related- transporters and their use in identifying chemosensitizers (Drug Resistance Updates (1999) 2 (371-381))
Drug Resistance Updates. 2000;3(1):66.

0
28.
2000

B. Ogretmen; J.C. Barredo; A.R. Safa

Increased expression of lung resistance-related protein and multidrug resistance-associated protein messenger RNA in childhood acute lymphoblastic leukemia
Journal of Pediatric Hematology/Oncology. 2000;22(1):45-49.

16
29.
2000

Mark R. Green; Melinda Harper; Ahmad Safa; Carol A. Sherman; Chaudry M. Mushtaq; Hamid Bahadori; Frank J. Brescia; Caio M.S.P. Rocha Lima

Irinotecan in the management of patients with pancreatic cancer
ONCOLOGY. 2000;14(12 SUPPL. 14):31-33.

3
30.
2000

Besim Ogretmen; Ahmad R. Safa

Identification and characterization of the MDR1 promoter-enhancing factor 1 (MEF1) in the multidrug resistant HL60/VCR human acute myeloid leukemia cell line
Biochemistry. 2000;39(1):194-204.

35
31.
1999

C.M.S. Rocha Lima; J.R. Eckardt; S.-S. Leong; C.A. Sherman; J.A. Perkel; T. Putman; A.R. Safa; H.R. Bahadori; M.R. Green

Single-agent gemcitabine and gemcitabine/irinotecan combination (IrimoGem) in non-small cell lung cancer
Seminars in Oncology. 1999;26(5 SUPPL. 16):43-50.

16
32.
1999

Hamid R. Bahadori; Caio Max S. Rocha Lima; Mark R. Green; Ahmad R. Safa

Synergistic effect of gemcitabine and irinotecan (CPT-11) on breast and small cell lung cancer cell lines
Anticancer Research. 1999;19(6 B):5423-5428.

40
33.
1999

Ahmad R. Safa

Photoaffinity analogs for multidrug resistance-related transporters and their use in identifying chemosensitizers
Drug Resistance Updates. 1999;2(6):371-381.

7
34.
1999

Besim Ogretmen; Ahmad R. Safa

Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-κb/p65 and c-Fos transcription factors and their interaction with the CAAT region
Biochemistry. 1999;38(7):2189-2199.

57
35.
1998

Besim Ogretmen; Hamid Bahadori; Mary McCauley; Alice Boylan; Mark Green; Ahmad R. Safa

Lack of correlation of MRP and γ-glutamylcysteine synthetase overexpression with doxorubicin resistance due to increased apoptosis in SV40 large T-antigen-transformed human mesothelial cells
Cancer Chemotherapy and Pharmacology. 1998;42(6):441-446.

4
36.
1998

M. Eileen Dolan; Benjamin Frydman; Craig B. Thompson; Alan M. Diamond; Bonnie J. Garbiras; Ahmad R. Safa; William T. Beck; Laurence J. Marton

Effects of 1,2-naphthoquinones on human tumor cell growth and lack of cross-resistance with other anticancer agents
Anti-Cancer Drugs. 1998;9(5):437-448.

37
37.
1998

Arthur E. Frankel; Philip D. Hall; Chris McLain; Ahmad R. Safa; Edward P. Tagge; Robert J. Kreitman

Cell-specific modulation of drug resistance in acute myeloid leukemic blasts by diphtheria fusion toxin, DT388-GMCSF
Bioconjugate Chemistry. 1998;9(4):490-496.

23
38.
1998

Ahmad R. Safa

Photoaffinity labels for characterizing drug interaction sites of P- glycoprotein
Methods in Enzymology. 1998;292:289-307.

30
39.
1998

Besim Ogretmen; Hamid R. Bahadori; Mary D. Mccauley; Alice Boylan; Mark R. Green; Ahmad R. Safa

Co-ordinated over-expression of the MRP and γ-glutamylcysteine synthetase genes, but not MDR1, correlates with doxorubicin resistance in human malignant mesothelioma cell lines
International Journal of Cancer. 1998;75(5):757-761.

28
40.
1998

Besim Ogretmen; Mary D. McCauley; Ahmad R. Safa

Molecular mechanisms of loss of β2-microglobulin expression in drug- resistant breast cancer sublines and its involvement in drug resistance
Biochemistry. 1998;37(33):11679-11691.

23
41.
1997

Olufunmilayo I. Olopade; Moses O. Adeyanju; Ahmad R. Safa; Fitsum Hagos; Rosemarie Mick; Craig B. Thompson; Wendy M. Recant

Overexpression of BCL-x protein in primary breast cancer is associated with high tumor grade and nodal metastases
Cancer Journal from Scientific American. 1997;3(4):230-237.

141
42.
1997

T.J. Lampidis; D. Kolonias; T. Podona; M. Israel; A.R. Safa; L. Lothstein; N. Savaraj; H. Tapiero; W. Priebe

Circumvention of P-GP MDR as a function of anthracycline lipophilicity and charge
Biochemistry. 1997;36(9):2679-2685.

60
43.
1997

Besim Ogretmen; Ahmad R. Safa

Expression of the mutated p53 tumor suppressor protein and its molecular and biochemical characterization in multidrug resistant MCF-7/Adr human breast cancer cells
Oncogene. 1997;14(4):499-506.

72
44.
1996

Alan M. Diamond; Deborah Jaffe; Judith L. Murray; Ahmad R. Safa; Brian L. Samuels; Dolph L. Hatfield

Lovastatin effects of human breast carcinoma cells. Differential toxicity of an adriamycin-resistant derivative and influence on selenocysteine tRNAs
Biochemistry and Molecular Biology International. 1996;38(2):345-355.

12
45.
1996

Besim Ogretmen; Cynthia Carpo; Ahmad R. Safa

Site-directed mutagenesis by unique site elimination using filamentous phage-derived ssDNA templates for plasmids that are resistant to denaturation
BioTechniques. 1996;21(2):209-213.

1
46.
1996

Besim Ogretmen; Ahmad R. Safa

Down-regulation of apoptosis-related bcl-2 but not bcl-x(L) or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells
International Journal of Cancer. 1996;67(5):608-614.

50
47.
1996

Elora Gupta; Ahmad R. Safa; Xiaolin Wang; Mark J. Ratain

Pharmacokinetic modulation of irinotecan and metabolites by cyclosporin A
Cancer Research. 1996;56(6):1309-1314.

65
48.
1996

Clifford W. Sachs; Larry M. Balks; S. Wayne Mascarella; Ahmad R. Safa; Anita H. Lewin; Carson Loomis; F. Ivy Carroll; Robert M. Bell; Robert L. Fine

Effects of sphingosine stereoisomers on P-glycoprotein phosphorylation and vinblastine accumulation in multidrug-resistant MCF-7 cells
Biochemical Pharmacology. 1996;52(4):603-612.

21
49.
1996

Lela E. Buckingham; M. Balasubramanian; Ahmad R. Safa; Himanshu Shah; Pavel Komarov; R. Martin Emanuele; John S. Coon

Reversal of multi-drug resistance in vitro by fatty acid-PEG-fatty acid diesters
International Journal of Cancer. 1996;65(1):74-79.

29
50.
1995

C.W. Sachs; A.R. Safa; S.D. Harrison; R.L. Fine

Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C
Journal of Biological Chemistry. 1995;270(44):26639-26648.

78
51.
1995

B. Ogretmen; A.R. Safa

Mini-preparation of total RNA for RT-PCR from cultured human cells
BioTechniques. 1995;19(3):374-375+377.

17
52.
1995

Danielle F. Cano-Gauci; Fabian S. Seibert; Ahmad R. Safa; John R. Riordan

Selection and characterization of verapamil-resistant multidrug resistant cells
Biochemical and Biophysical Research Communications. 1995;209(2):497-505.

3
53.
1994

N. Krishnamachary; L. Ma; L. Zheng; A.R. Safa; M.S. Center

Analysis of MRP gene expression and function in HL60 cells isolated for resistance to adriamycin
Oncology Research. 1994;6(3):119-127.

54
54.
1994

F.A. Sinicrope; J. Hart; T.A. Brasitus; F. Michelassi; J.J. Lee; A.R. Safa

Relationship of P-glycoprotein and carcinoembryonic antigen expression in human colon carcinoma to local invasion, DNA ploidy, and disease relapse
Cancer. 1994;74(11):2908-2917.

39
55.
1994

M. Nabil Benchekroun; Erasmus Schneider; Ahmad R. Safa; Alan J. Townsend; Birandra K. Sinha

Mechanisms of resistance to ansamycin antibiotics in human breast cancer cell lines
Molecular Pharmacology. 1994;46(4):677-684.

22
56.
1994

A.R. Safa; S. Roberts; M. Agresti; R.L. Fine

Tamoxifen aziridine, a novel affinity probe for P-glycoprotein in multidrug resistant cells
Biochemical and Biophysical Research Communications. 1994;202(1):606-612.

25
57.
1994

Ahmad R. Safa; Michael Agresti; David Bryk; Ikumi Tamai

N-(p-azido-3-[¹²⁵I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells
Biochemistry. 1994;33(1):256-265.

30
58.
1993

S. Kajiji; F. Talbot; K. Grizzuti; V. Van Dyke-Phillips; M. Agresti; A.R. Safa; P. Gros

Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site
Biochemistry. 1993;32(16):4185-4194.

67
59.
1993

B.L. Samuels; R. Mick; N.J. Vogelzang; S.F. Williams; R.L. Schilsky; A.R. Safa; S.M. O'Brien; M.J. Ratain

Modulation of vinblastine resistance with cyclosporine: A phase I study
Clinical Pharmacology and Therapeutics. 1993;54(4):421-429.

34
60.
1993

A.R. Safa

Photoaffinity labeling of P-glycoprotein in multidrug-resistant cells
Cancer Investigation. 1993;11(1):46-56.

31
61.
1992

F.A. Sinicrope; P.K. Dudeja; B.M. Bissonnette; A.R. Safa; T.A. Brasitus

Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesicles
Journal of Biological Chemistry. 1992;267(35):24995-25002.

105
62.
1992

A.R. Safa

Erratum: Photoaffinity labeling of P-glycoprotein in multidrug-resistant cells (Cancer Investigation 10(4), (1992))
Cancer Investigation. 1992;10(6):490-491.

0
63.
1992

G.F. Fleming; J.M. Amato; M. Agresti; A.R. Safa

Megestrol acetate reverses multidrug resistance and interacts with P-glycoprotein
Cancer Chemotherapy and Pharmacology. 1992;29(6):445-449.

40
64.
1992

A.R. Safa

Photoaffinity labeling of P-glycoprotein in multidrug-resistant cells
Cancer Investigation. 1992;10(4):295-305.

32
65.
1992

A. Rahman; S.R. Husain; J. Siddiqui; M. Verma; M. Agresti; M. Center; A.R. Safa; R.I. Glazer

Liposome-mediated modulation of multidrug resistance in human HL-60 leukemia cells
Journal of the National Cancer Institute. 1992;84(24):1909-1910.

59
66.
1991

B.L. Samuels; J.L. Murray; M.B. Cohen; A.R. Safa; B.K. Sinha; A.J. Townsend; M.A. Beckett; R.R. Weichselbaum

Increased glutathione peroxidase activity in a human sarcoma cell line with inherent doxorubicin resistance
Cancer Research. 1991;51(2):521-527.

44
67.
1991

I. Tamai; A.R. Safa

Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells
Journal of Biological Chemistry. 1991;266(25):16796-16800.

108
68.
1990

A.R. Safa; R.K. Stern; K. Choi; M. Agresti; I. Tamai; N.D. Mehta; I.B. Roninson

Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185 → Val-185 substitution in P-glycoprotein
Proceedings of the National Academy of Sciences of the United States of America. 1990;87(18):7225-7229.

82
69.
1990

Ahmad R. Sapa; Michael Agresti; Ikumi Tamai; Nitin D. Mehta; Soheila Vahabi

The α₁-adrenergic photoaffinity probe [¹²⁵I]arylazidoprazosin binds to a specific peptide of P-glycoprotein in multidrug-resistant cells
Biochemical and Biophysical Research Communications. 1990;166(1):259-266.

16
70.
1990

I. Tamai; A.R. Safa

Competitive interaction of cyclosporins with the Vinca alkaloid-binding site of P-glycoprotein in multidrug-resistant cells
Journal of Biological Chemistry. 1990;265(27):16509-16513.

106
71.
1989

A.R. Safa; N.D. Mehta; M. Agresti

Photoaffinity labeling of P-glycoprotein in multidrug resistant cells with photoactive analogs of colchicine
Biochemical and Biophysical Research Communications. 1989;162(3):1402-1408.

26
72.
1989

M.B. Meyers; L. Rittmann-Grauer; J.P. O'Brien; A.R. Safa

Characterization of monoclonal antibodies recognizing a M(r) 180,000 P-glycoprotein: Differential expression of the M(r) 180,000 and M(r) 170,000 P-glycoproteins in multidrug-resistant human tumor cells
Cancer Research. 1989;49(12):3209-3214.

24
73.
1989

T. McGrath; C. Latoud; S.T. Arnold; A.R. Safa; R.L. Felsted; M.S. Center

Mechanisms of multidrug resistance in HL60 cells. Analysis of resistance associated membrane proteins and levels of mdr gene expression
Biochemical Pharmacology. 1989;38(20):3611-3619.

77
74.
1989

Zuguang Ye; Knox Van Dyke; Terence Spearman; Ahmad R. Safa

³H-Azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria
Biochemical and Biophysical Research Communications. 1989;162(2):809-813.

0
75.
1989

H.L. Pearce; A.R. Safa; N.J. Bach; M.A. Winter; M.C. Cirtain; W.T. Beck

Essential features of the P-glycoprotein pharmacophore as defined by a series of reserpine analogs that modulate multidrug resistance
Proceedings of the National Academy of Sciences of the United States of America. 1989;86(13):5128-5132.

138
76.
1988

A.R. Safa

Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil
Proceedings of the National Academy of Sciences of the United States of America. 1988;85(19):7187-7191.

109
77.
1988

W.T. Beck; M.C. Cirtain; C.J. Glover; R.L. Felsted; A.R. Safa

Effects of indole alkaloids on multidrug resistance and labeling of P-glycoprotein by a photoaffinity analog of vinblastine
Biochemical and Biophysical Research Communications. 1988;153(3):959-966.

39
78.
1987

Ahmad R. Safa; Ernest Hamel; Ronald L. Felsted

Photoaffinity labeling of tubulin subunits with a photoactive analogue of vinblastine
Biochemistry. 1987;26(1):97-102.

25
79.
1987

A.R. Safa; R.L. Felsted

Specific Vinca alkaloid-binding polypeptides identified in calf brain by photoaffinity labeling
Journal of Biological Chemistry. 1987;262(3):1261-1267.

2
80.
1987

W.T. Beck; M.C. Cirtain; M.K. Danks; R.L. Felsted; A.R. Safa; J.S. Wolverton; D.P. Suttle; J.M. Trent

Pharmacological, molecular, and cytogenetic analysis of 'atypical' multidrug-resistant human leukemic cells
Cancer Research. 1987;47(20):5455-5460.

57
81.
1987

A.R. Safa; C.J. Glover; R.L. Felsted

Identification of Vinca alkaloid acceptors in P388 murine leukemia cells with a photoactive analogue of vinblastine
Cancer Research. 1987;47(19):5149-5154.

1
82.
1987

N. Chegini; A.R. Safa

Morphological alterations induced by prostaglandins E₁, F_2α and A₁ in MDA-MB-231 and MCF-7 human breast cancer cell lines
Cancer Letters. 1987;37(2):189-197.

0
83.
1987

A.R. Safa; C.J. Glover; J.L. Sewell; M.B. Meyers; J.L. Biedler; R.L. Felsted

Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for calcium channel blockers
Journal of Biological Chemistry. 1987;262(16):7884-7888.

105
84.
1987

N. Chegini; A.R. Safa

Influence of mitoxantrone on nucleolar function in MDA-MB-231 human breast tumor cell line
Cancer Letters. 1987;37(3):327-336.

4
85.
1986

A.R. Safa; C.J. Glover; M.B. Meyers; J.L. Biedler; R.L. Felsted

Vinblastine photoaffinity labeling of a high molecular weight surface membrane glycoprotein specific for multidrug-resistant cells
Journal of Biological Chemistry. 1986;261(14):6137-6140.

54
86.
1986

M.M. Cornwell; A.R. Safa; R.L. Felsted; M.M. Gottesman; I. Pastan

Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling
Proceedings of the National Academy of Sciences of the United States of America. 1986;83(11):3847-3850.

82
87.
1985

A.R. Safa; R.J. Ballou; M.T. Tseng

Growth and ultrastructural responses of T-47D human breast tumor cells to treatment with mitoxantrone.
Cancer Detection and Prevention. 1985;8(4):455-464.

0
88.
1985

A.R. Safa; R.L. Felsted

Identification of specific Vinca alkaloid binding polypeptides in the brain and tumor cells by photoaffinity labeling
Proceedings of the American Association for Cancer Research. 1985;VOL. 26:No. 29.

0
89.
1984

G.G. Goldin; A.R. Safa

Digitalis and cancer
Lancet. 1984;1(8386):1134.

13
90.
1984

N. Chegini; A.R. Safa; M.T. Tseng

Acute effects of mitoxantrone on the template activity of isolated nuclei from the T-47D human breast tumor cell line
Cancer Letters. 1984;21(3):329-336.

1
91.
1984

A.R. Safa; J.R. Brightwell; M.T. Tseng

Oestrogen dependence of lactate dehydrogenase and peroxidase in cell subpopulations of 7,12-dimethylbenz[α] anthracene-induced mammary tumours in the rat
Journal of Endocrinology. 1984;101(1):21-26.

0
92.
1984

A.R. Safa; M.T. Tseng

Inhibition of protein synthesis and cell proliferation in cultured human breast cancer cells treated with mitoxantrone
Cancer Letters. 1984;24(3):317-326.

0
93.
1983

A.R. Safa; M.T. Tseng

Doxorubicin-induced ultrastructural and growth changes in primary cultures of 7,12-dimethylbenz[a]anthracene-induced mammary tumors
Journal of the National Cancer Institute. 1983;70(3):535-540.

0
94.
1983

A.R. Safa; M.T. Tseng

Isolation and preparation of colonies grown on soft agar for ultrastructural investigation
Journal of Microscopy. 1983;130(1):119-122.

0
95.
1983

R.J. Ballou; A.R. Safa; M.T. Tseng

Response of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumor cells to tamoxifen, in vitro
Proceedings of the Society for Experimental Biology and Medicine. 1983;173(2):256-263.

0
96.
1983

M.T. Tseng; A.R. Safa

In vitro drug screening and individualized treatment planning for cancer patients.
Cancer Detection and Prevention. 1983;6(3):371-379.

2
97.
1983

A.R. Safa; M.T. Tseng

Lactate dehydrogenase activity in cell subpopulations of 7,12-dimethylbenz(a)anthracene-induced mammary tumors
Experientia. 1983;39(3):283-285.

0
98.
1983

M.T. Tseng; A.R. Safa; R. Ballou

Selective maintenance of cultured epithelial cells from DMBA-induced mammary tumours by bovine colostrum supplement
Cell and Tissue Kinetics. 1983;16(1):85-92.

0
99.
1983

A.R. Safa; N. Chegini; M.T. Tseng

Influence of mitoxantrone on nucleic acid synthesis on the T-47D breast tumor cell line
Journal of Cellular Biochemistry. 1983;22(2):111-120.

1
100.
1983

A.R. Safa; M.T. Tseng; R.J. Ballou

Sequential study on the influence of adriamycin on cell proliferation and ultrastructure of cultured mammary tumor cells
Proceedings of the Society for Experimental Biology and Medicine. 1983;174(2):276-283.

1
101.
1983

M.T. Tseng; A.R. Safa

Light, fluorescent, and electron microscopic analysis of cultured breast tumor cells (T-47D) treated with 9,10-anthracenedicarboxaldehyde bis[4,5-dihydro-1H-imidazol-2-yl)hydrazone] dihydrochloride
Cancer Research. 1983;43(12 I):5910-5914.

3
102.
1983

R.J. Ballou; A.R. Safa; M.T. Tseng

Improved visualization of cell nuclei in unstained cultured cells
Stain Technology. 1983;58(4):233-235.

0
103.
1982

A.R. Safa; M.T. Tseng

A simple method for scanning electron microscope preparation of cells grown in multiwell culture plates.
Stain Technology. 1982;57(2):107-112.

0
104.
1982

A.R. Safa; M.T. Tseng

Preparing autoradiographs of monolayer cell culture grown in polystyrene multiwell plates for scoring labeling indices.
Stain Technology. 1982;57(5):319-321.

0
105.
1982

M.T. Tseng; A.R. Safa; T. Halbig; S. Bertoloir

Colony forming capacity of cells derived from 7,12-dimethylbenz(a)anthracene induced mammary tumors in rat
Journal of Cell Biology. 1982;95(2 II):no.9073.

0
106.
1982

A.R. Safa; M.T. Tseng

Influence of inhibitors of plant cell division and wall formation on mammary tumor cells in primary culture
Federation Proceedings. 1982;41(4):No. 6090.

0
107.
1981

R.J. Ballou; A.R. Safa; M.T. Tseng

Effects of tamoxifen on cell subpopulations of 7,12-dimethylbenz(α)anthracene (DMBA)-induced rat mammary tumor in primary culture
Anatomical Record. 1981;199(3):17A.

0
108.
1981

M.T. Tseng; A.R. Safa

Influence of tamoxifen on ultrastructure and cell kinetics of 7,12-dimethylbenz[α]anthracene-induced mammary tumor cells in primary culture
IRCS Medical Science. 1981;9(4):281-282.

0
109.
1981

A.R. Safa; M.T. Tseng

Response to methotrexate of cultured cells of the 7,12-dimethylbenz(α) anthracene-induced mammary tumor of rats: A kinetic and ultrastructural study
IRCS Medical Science. 1981;9(6):522-523.

0
110.
1981

A.R. Safa; M.T. Tseng

Influence of tamoxifen and adriamycin on ultrastructure and surface topography of 7,12 dimethylbenz(α)anthracene (DMBA)-induced mammary tumor cells in primary culture
Journal of Cell Biology. 1981;91(2 II):No.6045.

0
111.
1981

M.T. Tseng; A.R. Safa; R.J. Ballou

Selective maintenance of epithelial cells from 7,12-dimethylbenz(a)anthracene-induced mammary tumor cells by colostrum supplementation
Journal of Cell Biology. 1981;91(2 II):No. 11018.

0

Ahmad R. Safa School of Medicine, Pharmacology & Toxicology

Ahmad R. Safa

111 Publications

Ahmad R. Safa
School of Medicine, Pharmacology & Toxicology