Nuria Morral

School of Medicine, Medical & Molecular Genetics

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Nuria Morral

• School of Medicine
  School of Medicine
  
  Medical & Molecular Genetics
  
  

  Current Appointments:

  Associate Professor of Medical & Molecular Genetics

  
  
  

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Núria Morral; Scott R. Witting

  ShRNA-induced interferon-stimulated gene analysis

  Methods in Molecular Biology. 2012;820:163-177.
  0

• 2.

  2011

  Jae-Seung Park; Sneha Surendran; Lisa M Kamendulis; Nria Morral

  Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies

  BMC Research Notes. 2011;4.
  5

• 3.

  2011

  M. Ahn; S.R. Witting; R. Ruiz; R. Saxena; N. Morral

  Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules

  Human Gene Therapy. 2011;22(12):1483-1497.
  1

• 4.

  2009

  Rafaela Ruiz; Scott R. Witting; Romil Saxena; Núria Morral

  Robust hepatic gene silencing for functional studies using helper-dependent adenoviral vectors

  Human Gene Therapy. 2009;20(1):87-94.
  10

• 5.

  2009

  Marcin P. Walkiewicz; Nuria Morral; Daniel A. Engel

  Accurate single-day titration of adenovirus vectors based on equivalence of protein VII nuclear dots and infectious particles

  Journal of Virological Methods. 2009;159(2):251-258.
  3

• 6.

  2008

  Scott R. Witting; Matthew Brown; Romil Saxena; Sarah Nabinger; Núria Morral

  Helper-dependent adenovirus-mediated short hairpin RNA expression in the liver activates the interferon response

  Journal of Biological Chemistry. 2008;283(4):2120-2128.
  17

• 7.

  2007

  Núria Morral; Howard J. Edenberg; Scott R. Witting; Jennifer Altomonte; Tearina Chu; Matthew Brown

  Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver

  Journal of Lipid Research. 2007;48(7):1499-1510.
  22

• 8.

  2007

  Jiangning Chen; Nuria Morral; Daniel A. Engel

  Transcription releases protein VII from adenovirus chromatin

  Virology. 2007;369(2):411-422.
  14

• 9.

  2004

  N. Morral

  Gene therapy for type 1 diabetes: New approaches

  Minerva Medica. 2004;95(2):93-104.
  5

• 10.

  2003

  Núria Morral

  Novel targets and therapeutic strategies for type 2 diabetes

  Trends in Endocrinology and Metabolism. 2003;14(4):169-175.
  29

• 11.

  2002

  H. Dong; K. Anthony; N. Morral

  Challenges for gene therapy of type 1 diabetes.

  Current gene therapy. 2002;2(4):403-414.
  4

• 12.

  2002

  Hengjiang Dong; Jennifer Altomonte; Nuria Morral; Marcia Meseck; Swan N. Thung; Savio L. C. Woo

  Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats

  Diabetes. 2002;51(1):130-138.
  26

• 13.

  2002

  Núria Morral; Wanda K. O'Neal; Karen Rice; M. Michelle Leland; Pedro A. Piedra; Estuardo Aguilar-Córdova; K. Dee Carey; Arthur L. Beaudet; Claire Langston

  Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

  Human Gene Therapy. 2002;13(1):143-154.
  115

• 14.

  2002

  Núria Morral; Robert McEvoy; Hengjiang Dong; Marcia Meseck; Jennifer Altomonte; Swan Thung; Savio L.C. Woo

  Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes

  Human Gene Therapy. 2002;13(13):1561-1570.
  16

• 15.

  2001

  Hengjiang Dong; Núria Morral; Robert McEvoy; Marcia Meseck; Swan N. Thung; Savio L.C. Woo

  Hepatic insulin expression improves glycemic control in type 1 diabetic rats

  Diabetes Research and Clinical Practice. 2001;52(3):153-163.
  29

• 16.

  2000

  W.K. O'Neal; H. Zhou; N. Morral; C. Langston; R.J. Parks; F.L. Graham; S. Kochanek; A.L. Beaudet

  Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

  Molecular medicine (Cambridge, Mass.). 2000;6(3):179-195.
  64

• 17.

  1999

  Lucio Pastore; Nuria Morral; Heshan Zhou; Racel Garcia; Robin J. Parks; Stefan Kochanek; Frank L. Graham; Brendan Lee; Arthur L. Beaudet

  Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors

  Human Gene Therapy. 1999;10(11):1773-1781.
  126

• 18.

  1999

  Núria Morral; Wanda O'Neal; Karen Rice; Michele Leland; Johanne Kaplan; Pedro A. Piedra; Heshan Zhou; Robin J. Parks; Rizwan Velji; Estuardo Aguilar-Córdova; et al.

  Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons

  Proceedings of the National Academy of Sciences of the United States of America. 1999;96(22):12816-12821.
  293

• 19.

  1998

  Gudrun Schiedner; Núria Morral; Robin J. Parks; Ying Wu; Suzanne C. Koopmans; Claire Langston; Frank L. Graham; Arthur L. Beaudet; Stefan Kochanek

  Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity

  Nature Genetics. 1998;18(2):180-183.
  446

• 20.

  1998

  Núria Morral; Robin J. Parks; Heshan Zhou; Claire Langston; Gudrun Schiedner; Janet Quinones; Frank L. Graham; Stefan Kochanek; Arthur L. Beaudet

  High doses of a helper-dependent adenoviral vector yield supraphysiological levels of α₁-antitrypsin with negligible toxicity

  Human Gene Therapy. 1998;9(18):2709-2716.
  187

• 21.

  1998

  Wanda K. O'Neal; Heshan Zhou; Núria Morral; Estuardo Aguilar-Cordova; Joseph Pestaner; Claire Langston; Benjamin Mull; Yufen Wang; Arthur L. Beaudet; Brendan Lee

  Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing α₁-antitrypsin after systemic delivery

  Human Gene Therapy. 1998;9(11):1587-1598.
  88

• 22.

  1997

  Núria Morral; Wanda O'Neal; Heshan Zhou; Claire Langston; Arthur Beaudet

  Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: Comparison of E2a wild type and E2a deleted vectors

  Human Gene Therapy. 1997;8(10):1275-1286.
  132

• 23.

  1996

  Mireille Claustres; Marie Desgeorges; Philippe Moine; Núria Morral; Xavier Estivill

  CFTR haplotypic variability far normal and mutant genes in cystic fibrosis families from southern France

  Human Genetics. 1996;98(3):336-344.
  24

• 24.

  1996

  N. Morral; T. Dork; R. Llevadot; V. Dziadek; B. Mercier; C. Ferec; B.B. Costes; E. Girodon; J. Zielenski; et al.

  Erratum: Haplotype analysis of 94 cystic fibrosis mutations with seven polymorphic CFTR DNA markers (Human Mutation (1996) 8 (149-159))

  Human Mutation. 1996;8(3):295.
  1

• 25.

  1996

  Heshan Zhou; Wanda O'Neal; Núria Morral; Arthur L. Beaudet

  Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted

  Journal of Virology. 1996;70(10):7030-7038.
  69

• 26.

  1996

  Núria Morral; Thilo Dörk; Roser Llevadot; Violetta Dziadek; Bernard Mercier; Claude Férec; Bruno Costes; Emmanuelle Girodon; Julian Zielenski; Lap-Chee Tsui; et al.

  Haplotype analysis of 94 cystic fibrosis mutations with seven polymorphic CFTR DNA markers

  Human Mutation. 1996;8(2):149-159.
  43

• 27.

  1995

  S.M. Cashman; A. Patino; A. Martinez; M. Garcia-Delgado; Z. Miedzybrodzka; M. Schwarz; A. Shrimpton; C. Ferec; O. Raguenes; M. Macek Jr.; et al.

  Identical intragenic microsatellite haplotype found in cystic fibrosis chromosomes bearing mutation G551D in Irish, English, Scottish, Breton and Czech patients

  Human Heredity. 1995;45(1):6-12.
  10

• 28.

  1995

  F. Mekus; T. Dork; T. Deufel; N. Morral; B. Tummler

  Analysis of microsatellites by direct blotting electrophoresis and chemiluminescence detection

  Electrophoresis. 1995;16(10):1886-1888.
  15

• 29.

  1994

  N.L. Kaplan; P.O. Lewis; B.S. Weir; X. Estivill; N. Morral; J. Bertranpetit

  Age of the ΔF508 cystic fibrosis mutation [1]

  Nature Genetics. 1994;8(3):216-218.
  22

• 30.

  1994

  J. Kere; X. Estivill; M. Chillon; N. Morral; V. Nunes; R. Norio; E. Savilahti; A. De la Chapelle

  Cystic fibrosis in a low-incidence population: Two major mutations in Finland

  Human Genetics. 1994;93(2):162-166.
  23

• 31.

  1994

  Núria Morral; Roser Llevadot; Teresa Casals; Paolo Gasparini; Milan Macek Jr.; Thilo Dörk; Xavier Estivill

  Independent origins of cystic fibrosis mutations R334W, R347P, R1162X, and 3849+10kbC→T provide evidence of mutation recurrence in the CFTR gene

  American Journal of Human Genetics. 1994;55(5):890-898.
  18

• 32.

  1994

  B. Mercier; O. Raguenes; X. Estivill; N. Morral; G.C. Kaplan; M. McClure; T.A. Grebe; D. Kessler; P.F. Pignatti; et al.

  Complete detection of mutations in cystic fibrosis patients of Native American origin

  Human Genetics. 1994;94(6):629-632.
  22

• 33.

  1994

  N. Morral; J. Bertranpetit; X. Estivill; V. Nunes; T. Casals; J. Giménez; A. Reis; R. Varon-Mateeva; M. Macek Jr.; L. Kalaydjieva; et al.

  The origin of the major cystic fibrosis mutation (ΔF508) in European populations

  Nature Genetics. 1994;7(2):169-175.
  183

• 34.

  1994

  Miguel Chillón; Teresa Casals; Javier Giménez; M.Dolores Ramos; Ana Palacio; Nuria Morral; Xavier Estivill; Virginia Nunes

  Analysis of the CFTR gene confirms the high genetic heterogeneity of the Spanish population: 43 mutations account for only 78% of CF chromosomes

  Human Genetics. 1994;93(4):447-451.
  54

• 35.

  1993

  Núria Morral; Virginia Nunes; Teresa Casals; Nicolás Cobos; Oscar Asensio; Javier Dapena; Xavier Estivill

  Uniparental inheritance of microsatellite alleles of the cystic fibrosis gene (CFTR): Identification of a 50 kilobase deletion

  Human Molecular Genetics. 1993;2(6):677-681.
  22

• 36.

  1993

  Núria Morral; Virginia Nunes; Teresa Casals; Miguel Chillón; Javier Giménez; Jaume Bertranpetit; Xavier Estivill

  Microsatellite haplotypes for cystic fibrosis: Mutation frameworks and evolutionary tracers

  Human Molecular Genetics. 1993;2(7):1015-1022.
  50

• 37.

  1993

  Teresa Casals; Virginia Nunes; Ana Palacio; Javier Giménez; Antonia Gaona; Núria Ibáñez; Núria Morral; Xavier Estivill

  Cystic fibrosis in Spain: high frequency of mutation G542X in the Mediterranean coastal area

  Human Genetics. 1993;91(1):66-70.
  26

• 38.

  1992

  N. Morral; E. Girbau; J. Zielenski; V. Nunes; T. Casals; L.-C. Tsui; X. Estivill

  Dinucleotide (CA/GT) repeat polymorphism in intron 17B of the cystic fibrosis transmembrane conductance regulator (CFTR) gene

  Human Genetics. 1992;88(3):356.
  13

• 39.

  1992

  F. Posas; A. Casamayor; N. Morral; J. Arino

  Molecular cloning and analysis of a yeast protein phosphatase with an unusual amino-terminal region

  Journal of Biological Chemistry. 1992;267(17):11734-11740.
  33

• 40.

  1992

  Núria Morral; Xavier Estivill

  Multiplex PCR amplification of three microsatellites within the CFTR gene

  Genomics. 1992;13(4):1362-1364.
  45

• 41.

  1991

  P. Gasparini; M. Dognini; A. Bonizzato; P.F. Pignatti; N. Morral; X. Estivill

  A tetranucleotide repeat polymorphism in the cystic fibrosis gene

  Human Genetics. 1991;86(6):625.
  15

• 42.

  1991

  P. Gasparini; V. Nunes; A. Savoia; M. Dognini; N. Morral; A. Gaona; A. Bonizzato; M. Chillon; F. Sangiuolo; G. Novelli; et al.

  The search for South European cystic fibrosis mutations: Identification of two new mutations, four variants, and intronic sequences

  Genomics. 1991;10(1):193-200.
  33

• 43.

  1991

  Núria Morral; Virginia Nunes; Teresa Casals; Xavier Estivill

  CA GT Microsatellite alleles within the cystic fibrosis transmembrane conductance regulator (CFTR) gene are not generated by unequal crossingover

  Genomics. 1991;10(3):692-698.
  43

• 44.

  1991

  X. Estivill; N. Morral; T. Casals; V. Nunes

  Prenatal diagnosis of cystic fibrosis by multiplex PCR of mutation and microsatellite alleles [ 30]

  Lancet. 1991;338(8764):458.
  2

• 45.

  1990

  M. Chillón; T. Casals; F.J. Giménez; H. Badía; N. Morral; A. Bosch; V. Nunes; X. Estivill

  Use of the polymerase chain reaction technic in the genetic analysis of cystic fibrosis

  Medicina clinica. 1990;94(12):444-447.
  0

• 46.

  1989

  X. Estivill; T. Casals; N. Morral; M. Chillon; A. Bosch; V. Nunes; P. Gasparini; A. Seia; P.F. Pignatti; G. Novelli; et al.

  ΔF₅₀₈ gene deletion in cystic fibrosis in southern Europe

  Lancet. 1989;2(8676):1404.
  11