Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
High doses of a helper-dependent adenoviral vector yield supraphysiological levels of α1-antitrypsin with negligible toxicity
Núria Morral; Robin J. Parks; Heshan Zhou; Claire Langston; Gudrun Schiedner; Janet Quinones; Frank L. Graham; Stefan Kochanek; Arthur L. Beaudet (Profiled Author: Nuria Morral)
Human Gene Therapy. 1998;9(18):2709-2716.Abstract
Optimal gene therapy for many disorders will require efficient transfer to cells in vivo, high-level and long-term expression, and tissue-specific regulation, all in the absence of significant toxicity or inflammatory responses. While recombinant adenoviral vectors are efficient for gene transfer to hepatocytes, their usefulness is limited by short duration of expression related, at least in part, to immune responses to viral proteins and by a low capacity for foreign DNA. A number of systems have been developed for producing adenoviral vectors devoid of all viral coding sequences. Using AdSTK109, a vector lacking all viral coding sequences and carrying the complete human α
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Lucio Pastore; Nuria Morral; Heshan Zhou; Racel Garcia; Robin J. Parks; Stefan Kochanek; Frank L. Graham; Brendan Lee; Arthur L. BeaudetHuman Gene Therapy. 1999;10(11):1773-1781.
W.K. O'Neal; H. Zhou; N. Morral; C. Langston; R.J. Parks; F.L. Graham; S. Kochanek; A.L. BeaudetMolecular medicine (Cambridge, Mass.). 2000;6(3):179-195.
Gudrun Schiedner; Núria Morral; Robin J. Parks; Ying Wu; Suzanne C. Koopmans; Claire Langston; Frank L. Graham; Arthur L. Beaudet; Stefan KochanekNature Genetics. 1998;18(2):180-183.
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