Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Transcatheter Arterial Embolization with Only Particles for the Treatment of Unresectable Hepatocellular Carcinoma
Mary A. Maluccio; Anne M. Covey; Leah Ben Porat; Joanna Schubert; Lynn A. Brody; Constantinos T. Sofocleous; George I. Getrajdman; William Jarnagin; Ronald DeMatteo; Leslie H. Blumgart; et al. (Profiled Author: Mary A. Maluccio)
Journal of Vascular and Interventional Radiology. 2008;19(6):862-869.Abstract
Purpose: To determine the survival of patients with hepatocellular carcinoma (HCC) treated with a standardized method of transcatheter arterial embolization (TAE) with small embolic particles intended to impart terminal vessel blockade, and to evaluate prognostic factors that impact overall survival. Materials and Methods: A total of 322 patients with HCC who underwent 766 embolizations from January 1997 to December 2004 were retrospectively reviewed. Selective embolization of vessels feeding individual tumors was performed with small (50 μm) polyvinyl alcohol or spherical embolic particles (40-120 μm) intended to cause terminal vessel blockade. Repeat embolization was performed in cases of evidence of persistent viable tumor or development of new lesions. Patient, tumor, and treatment characteristics were prospectively recorded and tested for prognostic significance by univariate and multivariate analysis. Results: The median survival time was 21 months, with 1-, 2-, and 3-year overall survival rates of 66%, 46%, and 33%, respectively. In patients without extrahepatic disease or portal vein involvement by tumor, the overall 1-, 2-, and 3-year survival rates increased to 84%, 66%, and 51%, respectively. Okuda stage, extrahepatic disease, diffuse disease (≥5 tumors), and tumor size were independent predictors of survival on multivariate analysis. There were 90 complications (11.9%) in 75 patients, including eight deaths (2.5%), within 30 days of embolization. Conclusions: Hepatic arterial embolization with small particles to cause terminal vessel blockade is an effective treatment method for patients with unresectable HCC. These data support our hypothesis that particles alone may be the critical component of catheter-directed embolotherapy. © 2008 SIR.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Shenghong Ju; Gordon McLennan; Stacy L. Bennett; Yun Liang; Laurent Bonnac; Krzysztof W. Pankiewicz; Hiremagalur N. Jayaram
Technical Aspects of Imaging and Transfemoral Arterial Treatment of N1-S1 Tumors in Rats: An Appropriate Model to Test the Biology and Therapeutic Response to Transarterial Treatments of Liver CancersJournal of Vascular and Interventional Radiology. 2009;20(3):410-414.
Raymond H. Thornton; Anne Covey; Elena N. Petre; Elyn R. Riedel; Mary A. Maluccio; Constantinos T. Sofocleous; Lynn A. Brody; George I. Getrajdman; Michael D'Angelica; Yuman Fong; et al.Cancer. 2009;115(21):5000-5006.
Mary Maluccio; Anne CoveyCA Cancer Journal for Clinicians. 2012;62(6):394-399.
Appears in this Document