Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Christopher P. Hess; H.J. Fullerton; D.W. Metry; B.A. Drolet; D.H. Siegel; K.I. Auguste; N. Gupta; A.N. Haggstrom; C.F. Dowd; I.J. Frieden; et al. (Profiled Author: Anita N. Haggstrom)
American Journal of Neuroradiology. 2010;31(10):1980-1986.Abstract
BACKGROUND AND PURPOSE: Cerebral and cervical arterial abnormalities are the most common non-cutaneous anomaly in PHACE syndrome, but the location and type of arterial lesions that occur have not been systematically assessed in a large cohort. Our aim was to characterize the phenotypic spectrum of arteriopathy, assess the frequency with which different arteries are involved, and evaluate spatial relationships between arteriopathy, brain structural lesions, and hemangiomas in PHACE syndrome. MATERIALS AND METHODS: Intracranial MRA and/or CTA images from 70 children and accompanying brain MR images in 59 patients with arteriopathy and PHACE syndrome were reviewed to identify the type and location of arterial lesions and brain abnormalities. Five categories of arteriopathy were identified and used for classification: dysgenesis, narrowing, nonvisualization, primitive embryonic carotid-vertebrobasilar connections, and anomalous arterial course or origin. Univariate logistic regression analyses were performed to test for associations between arteriopathy location, hemangiomas, and brain abnormalities. RESULTS: By study design, all patients had arterial abnormalities, and 57% had >1 form of arteriopathy. Dysgenesis was the most common abnormality (56%), followed by anomalous course and/or origin (47%), narrowing (39%), and nonvisualization (20%). Primitive embryonic carotid-vertebrobasilar connections were present in 20% of children. Hemangiomas were ipsilateral to arteriopathy in all but 1 case. The frontotemporal and/or mandibular facial segments were involved in 97% of cases, but no other specific associations between arteriopathy location and hemangioma sites were detected. All cases with posterior fossa anomalies had either ICA anomalies or persistent embryonic carotid-basilar connections. CONCLUSIONS: The arteriopathy of PHACE syndrome commonly involves the ICA and its embryonic branches, ipsilateral to the cutaneous hemangioma, with dysgenesis and abnormal arterial course the most commonly noted abnormalities. Brain abnormalities are also typically ipsilateral.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
R. Shane Tubbs; Martin M. Mortazavi; Andrew J. Denardo; Aaron A. Cohen-GadolSurgical and Radiologic Anatomy. 2012;34(2):191-193.
Todd D. Vogel; Charles G. Kulwin; Andrew J. Denardo; Troy D. Payner; Joel C. Boaz; Daniel H. FulkersonJournal of Neurosurgery: Pediatrics. 2011;7(6):633-636.
R. Shane Tubbs; Ketan Verm; Sheryl Riech; Martin M. Mortazavi; Mohammadali M. Shoja; Marios Loukas; Joel K. Curé; Anna Zurada; Aaron A. Cohen-GadolJournal of Neurosurgery. 2011;114(4):1127-1134.
Appears in this Document