Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Patterns of baseline autonomic nerve activity and the development of pacing-induced sustained atrial fibrillation
Mark J. Shen; Eue-Keun Choi; Alex Y. Tan; Seongwook Han; Tetsuji Shinohara; Mitsunori Maruyama; Lan S. Chen; Changyu Shen; Chun Hwang; Shien-Fong Lin; et al. (Profiled Authors: Changyu Shen; Peng-Sheng Chen; Shien-Fong Lin; Lan Chen)
Heart Rhythm. 2011;8(4):583-589.Abstract
Background: Whether autonomic nerve activity is important in the development of pacing-induced sustained atrial fibrillation (AF) is unclear. Objective: The purpose of this study was to test the hypothesis that patterns of baseline autonomic nerve activity are important in the development of pacing-induced sustained AF. Methods: Radiotransmitters were implanted in 12 ambulatory dogs to record left stellate ganglion nerve activity (SGNA) and vagal nerve activity (VNA). Sustained (>48 hours) AF was induced with intermittent rapid atrial pacing. Results: At baseline (before pacing), 1-minute integrated nerve activity between SGNA and VNA demonstrated either a single linear relationship with excellent correlation (group 1, N = 3, r = 0.816 ± 0.105) or nonlinear relationships with poor correlation (group 2, N = 9, r = 0.316 ± 0.162, P <.05 vs group 1). Group 1 dogs had higher VNA (97.0 ± 11.5 mV-s) compared to group 2 (33.4 ± 21.7 mV-s, P <.001). Group 1 dogs had more frequent sympathovagal co-activation episodes than did group 2 (50 ± 19 per day vs 15 ± 6 per day, P <.05) and more paroxysmal atrial tachycardia (PAT; 5 ± 1 per day vs 2 ± 1 per day, P <.05) at baseline. Sustained AF occurred after 16 ± 4 days (range 1320 days) of pacing in group 1 and after 46 ± 18 days (range 2372 days) of pacing in group 2 (P <.05). In the week before development of sustained AF, VNA of group 2 dogs was significantly increased compared to baseline (P <.05). Conclusion: Ambulatory dogs with good linear sympathovagal correlation and higher vagal tone at baseline have more PAT episodes at baseline and faster induction of sustained AF by rapid pacing. Rapid atrial pacing increased the VNA of the remaining dogs before induction of sustained AF. © 2011 Heart Rhythm Society.
PMID: 21118728 PMCID: PMC3065927
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Masahiro Ogawa; Alex Y. Tan; Juan Song; Kenzaburo Kobayashi; Michael C. Fishbein; Shien-Fong Lin; Lan S. Chen; Peng-Sheng ChenHeart Rhythm. 2009;6(12):1772-1779.
Yuji Okuyama; Yasushi Miyauchi; Angela M. Park; Akira Hamabe; Shengmei Zhou; Hideki Hayashi; Mizuho Miyauchi; Chikaya Omichi; Hui-Nam Pak; Lauren A. Brodsky; et al.Journal of the American College of Cardiology. 2003;42(2):348-360.
Hideki Hayashi; Charles Wang; Yasushi Miyauchi; Chikaya Omichi; Hui-Nam Pak; Shengmei Zhou; Toshihiko Ohara; William J. Mandel; Shien-Fong Lin; Michael C. Fishbein; et al.Journal of Cardiovascular Electrophysiology. 2002;13(8):801-808.
Appears in this Document