JAD - SciVal Experts v3.6

252 Publications

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications for this application is PubMed, so only PubMed publications are included.

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1.
2013

Chen Yao; William M Johnson; Yue Gao; Wen Wang; Jinwei Zhang; Maria Deak; Dario R Alessi; Xiongwei Zhu; John J Mieyal; Hanno Roder; et al.

Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity.
Human molecular genetics 2013;22(2):328-44.
2.
2013

George Perry; Xiongwei Zhu; Mark A Smith; Aaron Sorensen; Jesús Avila

Preface. Alzheimer's disease: advances for a new century.
Journal of Alzheimer's disease : JAD 2013;33 Suppl 1():S1.
3.
2013

Xiongwei Zhu; George Perry; Mark A Smith; Xinglong Wang

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;33 Suppl 1():S253-62.
4.
2012

Akihiko Nunomura; Paula I Moreira; Rudy J Castellani; Hyoung-Gon Lee; Xiongwei Zhu; Mark A Smith; George Perry

Oxidative damage to RNA in aging and neurodegenerative disorders.
Neurotoxicity research 2012;22(3):231-48.
5.
2012

Xinglong Wang; Timothy G Petrie; Yingchao Liu; Jun Liu; Hisashi Fujioka; Xiongwei Zhu

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction.
Journal of neurochemistry 2012;121(5):830-9.
6.
2012

Xinglong Wang; Mike Snape; Eric Klann; Jeremy G Stone; Avneet Singh; Robert B Petersen; Rudy J Castellani; Gemma Casadesus; Mark A Smith; Xiongwei Zhu

Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome.
Journal of neurochemistry 2012;121(4):672-9.
7.
2012

Xinglong Wang; Michael H Yan; Hisashi Fujioka; Jun Liu; Amy Wilson-Delfosse; Shu G Chen; George Perry; Gemma Casadesus; Xiongwei Zhu

LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1.
Human molecular genetics 2012;21(9):1931-44.
8.
2012

Renato X Santos; Sónia C Correia; Xiongwei Zhu; Hyoung-Gon Lee; Robert B Petersen; Akihiko Nunomura; Mark A Smith; George Perry; Paula I Moreira

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease.
Free radical research 2012;46(4):565-76.
9.
2012

Wataru Kudo; Hyun-Pil Lee; Wen-Quan Zou; Xinglong Wang; George Perry; Xiongwei Zhu; Mark A Smith; Robert B Petersen; Hyoung-gon Lee

Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death.
Human molecular genetics 2012;21(5):1138-44.
10.
2012

Xiongwei Zhu; Rudy J Castellani; Nicholas P Ziats; Robert B Petersen; Hyoung Gon Lee; George Perry

Mark A. Smith: neurocytochemistry innovator.
Journal of neurochemistry 2012;120(6):1139-40.
11.
2012

Akihiko Nunomura; Toshio Tamaoki; Nobutaka Motohashi; Masao Nakamura; Daniel W McKeel; Massimo Tabaton; Hyoung-Gon Lee; Mark A Smith; George Perry; Xiongwei Zhu

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons.
Journal of neuropathology and experimental neurology 2012;71(3):233-41.
12.
2012

Rudy J Castellani; Paula I Moreira; George Perry; Xiongwei Zhu

The role of iron as a mediator of oxidative stress in Alzheimer disease.
BioFactors (Oxford, England) 2012;38(2):133-8.
13.
2012

Xiongwei Zhu; Rudy J Castellani; Paula I Moreira; Gjumrakch Aliev; Justin C Shenk; Sandra L Siedlak; Peggy L R Harris; Hisashi Fujioka; Lawrence M Sayre; Pamela A Szweda; et al.

Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.
Free radical biology & medicine 2012;52(3):699-704.
14.
2012

David J Bonda; Gang Liu; Ping Men; George Perry; Mark A Smith; Xiongwei Zhu

Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming!
CNS & neurological disorders drug targets 2012;11(1):81-5.
15.
2012

Siddhartha Mondragón-Rodríguez; George Perry; Xiongwei Zhu; Jannic Boehm

Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy.
International journal of Alzheimer's disease 2012;2012():630182.
16.
2012

Siddhartha Mondragón-Rodríguez; George Perry; Xiongwei Zhu; Paula I Moreira; Sylvain Williams

Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target?
International journal of Alzheimer's disease 2012;2012():276803.
17.
2012

Janelle N Fawver; Karen T Duong; Olivia Wise-Scira; Rachel Petrofes Chapa; Hayley E Schall; Orkid Coskuner; Xiongwei Zhu; Luis V Colom; Ian V J Murray

Probing and trapping a sensitive conformation: amyloid-β fibrils, oligomers, and dimers.
Journal of Alzheimer's disease : JAD 2012;32(1):197-215.
18.
2012

George Perry; Clyde F Phelix; Akihiko Nunomura; Luis V Colom; Rudy J Castellani; Robert B Petersen; Hyoung-gon Lee; Xiongwei Zhu

Untangling the vascular web from Alzheimer disease and oxidative stress.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2012;39(1):4.
19.
2012

Hyun-Pil Lee; Neel Pancholi; Luke Esposito; Laura A Previll; Xinglong Wang; Xiongwei Zhu; Mark A Smith; Hyoung-gon Lee

Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity.
PloS one 2012;7(1):e28033.
20.
2012

Arlene Reed-Cossairt; Xiongwei Zhu; Hyoung-Gon Lee; Charles Reed; George Perry; Robert B Petersen

Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome.
Current gerontology and geriatrics research 2012;2012():929734.
21.
2012

Janelle N Fawver; Hayley E Schall; Rachel D Petrofes Chapa; Xiongwei Zhu; Ian V J Murray

Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding.
Journal of Alzheimer's disease : JAD 2012;30(1):63-73.
22.
2012

Sónia C Correia; Renato X Santos; George Perry; Xiongwei Zhu; Paula I Moreira; Mark A Smith

Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases.
Advances in experimental medicine and biology 2012;724():205-21.
23.
2011

Rudy J Castellani; Yashi Gupta; Baiyang Sheng; Sandra L Siedlak; Peggy Lr Harris; Jeff M Coller; George Perry; Hyoung-Gon Lee; Massimo Tabaton; Mark A Smith; et al.

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules.
Laboratory investigation; a journal of technical methods and pathology 2011;91(12):1777-86.
24.
2011

Hyun-Pil Lee; Wataru Kudo; Xiongwei Zhu; Mark A Smith; Hyoung-gon Lee

Early induction of c-Myc is associated with neuronal cell death.
Neuroscience letters 2011;505(2):124-7.
25.
2011

Rudy J Castellani; Robert B Petersen; Hyoung-gon Lee; Xiongwei Zhu; George Perry

Mark A. Smith: the scientist, the man.
International journal of experimental pathology 2011;92(5):297-8.
26.
2011

Xinglong Wang; Bo Su; Wanhong Liu; Xiaohua He; Yuan Gao; Rudy J Castellani; George Perry; Mark A Smith; Xiongwei Zhu

DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease.
Aging cell 2011;10(5):807-23.
27.
2011

Vladan P Bajić; Bo Su; Hyoung-Gon Lee; Wataru Kudo; Sandra L Siedlak; Lada Zivković; Biljana Spremo-Potparević; Ninoslav Djelic; Zorana Milicevic; Avneet K Singh; et al.

Mislocalization of CDK11/PITSLRE, a regulator of the G2/M phase of the cell cycle, in Alzheimer disease.
Cellular & molecular biology letters 2011;16(3):359-72.
28.
2011

Jeremy G Stone; Sandra L Siedlak; Massimo Tabaton; Asao Hirano; Rudy J Castellani; Corrado Santocanale; George Perry; Mark A Smith; Xiongwei Zhu; Hyoung-gon Lee

The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies.
Journal of neuropathology and experimental neurology 2011;70(7):578-87.
29.
2011

Julie A Wolfram; Anna Liner; Sandy L Richardson; Xiongwei Zhu; Mark A Smith; Brian D Hoit; Hyoung-Gon Lee

The role of E2F1 in the development of hypertrophic cardiomyopathy.
International journal of clinical and experimental pathology 2011;4(5):521-5.
30.
2011

Wen-Quan Zou; Xiangzhu Xiao; Jue Yuan; Gianfranco Puoti; Hisashi Fujioka; Xinglong Wang; Sandy Richardson; Xiaochen Zhou; Roger Zou; Shihao Li; et al.

Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain.
The Journal of biological chemistry 2011;286(17):15095-105.
31.
2011

Sónia C Correia; Renato X Santos; George Perry; Xiongwei Zhu; Paula I Moreira; Mark A Smith

Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?
Ageing research reviews 2011;10(2):264-73.
32.
2011

David J Bonda; Hyoung-gon Lee; Jeffrey A Blair; Xiongwei Zhu; George Perry; Mark A Smith

Role of metal dyshomeostasis in Alzheimer's disease.
Metallomics : integrated biometal science 2011;3(3):267-70.
33.
2011

David J Bonda; Hyoung-Gon Lee; Antoni Camins; Mercè Pallàs; Gemma Casadesus; Mark A Smith; Xiongwei Zhu

The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations.
Lancet neurology 2011;10(3):275-9.
34.
2011

George Perry; Xiongwei Zhu

Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease.
Journal of Alzheimer's disease : JAD 2011;24(1):1-2.
35.
2011

Rudy J Castellani; Summer L Nugent; Alan L Morrison; Xiongwei Zhu; Hyoung-Gon Lee; Peggy L R Harris; Vladan Bajić; Hari S Sharma; Shu G Chen; Peter Oettgen; et al.

CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(1):23-6.
36.
2011

Calvin Moh; Jacek Z Kubiak; Vladan P Bajic; Xiongwei Zhu; Mark A Smith; Hyoung-Gon Lee

Cell cycle deregulation in the neurons of Alzheimer's disease.
Results and problems in cell differentiation 2011;53():565-76.
37.
2011

Jeremy G Stone; Gemma Casadesus; Kasia Gustaw-Rothenberg; Sandra L Siedlak; Xinglong Wang; Xiongwei Zhu; George Perry; Rudy J Castellani; Mark A Smith

Frontiers in Alzheimer's disease therapeutics.
Therapeutic advances in chronic disease 2011;2(1):9-23.
38.
2011

David J Bonda; Mark A Smith; George Perry; Hyoung-gon Lee; Xinglong Wang; Xiongwei Zhu

The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention.
Current pharmaceutical design 2011;17(31):3374-80.
39.
2011

Quan Liu; Fang Xie; Abdiel Alvarado-Diaz; Mark A Smith; Paula I Moreira; Xiongwei Zhu; George Perry

Neurofilamentopathy in neurodegenerative diseases.
The open neurology journal 2011;5():58-62.
40.
2011

Nicholas P Ziats; Robert B Petersen; Hyoung-Gon Lee; Rudy J Castellani; George Perry; Xiongwei Zhu

Mark A. Smith, 1965-2010: consummate student of pathogenesis.
International journal of clinical and experimental pathology 2011;4(7):731-2.
41.
2010

Jonathon E Heath; Sandra L Siedlak; Xiongwei Zhu; Hyoung-Gon Lee; Akanksha Thakur; Riqiang Yan; George Perry; Mark A Smith; Rudy J Castellani

Widespread distribution of reticulon-3 in various neurodegenerative diseases.
Neuropathology : official journal of the Japanese Society of Neuropathology 2010;30(6):574-9.
42.
2010

Chen Yao; Rabih El Khoury; Wen Wang; Tara A Byrd; Elizabeth A Pehek; Colin Thacker; Xiongwei Zhu; Mark A Smith; Amy L Wilson-Delfosse; Shu G Chen

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease.
Neurobiology of disease 2010;40(1):73-81.
43.
2010

Barney E Dwyer; Leo R Zacharski; Dominic J Balestra; Alan J Lerner; George Perry; Xiongwei Zhu; Mark A Smith

Potential role of iron in a Mediterranean-style diet.
Archives of neurology 2010;67(10):1286-7; author reply 1287-8.
44.
2010

David J Bonda; Xinglong Wang; George Perry; Akihiko Nunomura; Massimo Tabaton; Xiongwei Zhu; Mark A Smith

Oxidative stress in Alzheimer disease: a possibility for prevention.
Neuropharmacology 2010;59(4-5):290-4.
45.
2010

María F Galindo; Ichiro Ikuta; Xiongwei Zhu; Gemma Casadesus; Joaquín Jordán

Mitochondrial biology in Alzheimer's disease pathogenesis.
Journal of neurochemistry 2010;114(4):933-45.
46.
2010

Hyun Pil Lee; Xiongwei Zhu; Gemma Casadesus; Rudy J Castellani; Akihiko Nunomura; Mark A Smith; Hyoung-gon Lee; George Perry

Antioxidant approaches for the treatment of Alzheimer's disease.
Expert review of neurotherapeutics 2010;10(7):1201-8.
47.
2010

Paula I Moreira; Renato X Santos; Xiongwei Zhu; Hyoung-gon Lee; Mark A Smith; Gemma Casadesus; George Perry

Autophagy in Alzheimer's disease.
Expert review of neurotherapeutics 2010;10(7):1209-18.
48.
2010

Bo Su; Xinglong Wang; David Bonda; Gorge Perry; Mark Smith; Xiongwei Zhu

Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease?
Molecular neurobiology 2010;41(2-3):87-96.
49.
2010

Elena Bevilacqua; Xinglong Wang; Mithu Majumder; Francesca Gaccioli; Celvie L Yuan; Chuanping Wang; Xiongwei Zhu; Lindsay E Jordan; Donalyn Scheuner; Randal J Kaufman; et al.

eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress.
The Journal of biological chemistry 2010;285(22):17098-111.
50.
2010

Siddhartha Mondragón-Rodríguez; Gustavo Basurto-Islas; Hyoung-gon Lee; George Perry; Xiongwei Zhu; Rudy J Castellani; Mark A Smith

Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.
Expert review of neurotherapeutics 2010;10(5):683-91.
51.
2010

Hyun-pil Lee; Xiongwei Zhu; Gang Liu; Shu G Chen; George Perry; Mark A Smith; Hyoung-gon Lee

Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship.
Cell research 2010;20(4):397-9.
52.
2010

D J Bonda; V P Bajić; B Spremo-Potparevic; G Casadesus; X Zhu; M A Smith; H-G Lee

Review: cell cycle aberrations and neurodegeneration.
Neuropathology and applied neurobiology 2010;36(2):157-63.
53.
2010

Akihiko Nunomura; Toshio Tamaoki; Koich Tanaka; Nobutaka Motohashi; Masao Nakamura; Takaaki Hayashi; Haruyasu Yamaguchi; Shun Shimohama; Hyoung-gon Lee; Xiongwei Zhu; et al.

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease.
Neurobiology of disease 2010;37(3):731-7.
54.
2010

Xiongwei Zhu

Ultrashort high quality electron beam from laser wakefield accelerator using two-step plasma density profile.
The Review of scientific instruments 2010;81(3):033307.
55.
2010

David J Bonda; Hyun-Pil Lee; Hyoung-gon Lee; Avi L Friedlich; George Perry; Xiongwei Zhu; Mark A Smith

Novel therapeutics for Alzheimer's disease: an update.
Current opinion in drug discovery & development 2010;13(2):235-46.
56.
2010

David J Bonda; Xinglong Wang; George Perry; Mark A Smith; Xiongwei Zhu

Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies.
Drugs & aging 2010;27(3):181-92.
57.
2010

Katarzyna Gustaw-Rothenberg; Alan Lerner; David J Bonda; Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A Smith

Biomarkers in Alzheimer's disease: past, present and future.
Biomarkers in medicine 2010;4(1):15-26.
58.
2010

Massimo Tabaton; George Perry; Xiongwei Zhu; Hyoung-gon Lee; Gemma Casadesus; Mark A Smith

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease.
The American journal of pathology 2010;176(2):540-1.
59.
2010

Kathryn J Bryan; Joseph C Mudd; Sandy L Richardson; Jaewon Chang; Hyoung-Gon Lee; Xiongwei Zhu; Mark A Smith; Gemma Casadesus

Down-regulation of serum gonadotropins is as effective as estrogen replacement at improving menopause-associated cognitive deficits.
Journal of neurochemistry 2010;112(4):870-81.
60.
2010

Bo Su; Xinglong Wang; Hyoung-Gon Lee; Massimo Tabaton; George Perry; Mark A Smith; Xiongwei Zhu

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells.
Neuroscience letters 2010;468(3):267-71.
61.
2010

Paula I Moreira; Lawrence M Sayre; Xiongwei Zhu; Akihiko Nunomura; Mark A Smith; George Perry

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.
Methods in molecular biology (Clifton, N.J.) 2010;610():419-34.
62.
2010

Xiongwei Zhu

Mitochondrial dysfunction: mitochondrial diseases and pathways with a focus on neurodegeneration. Preface.
Biochimica et biophysica acta 2010;1802(1):1.
63.
2010

Mark A Smith; Xiongwei Zhu; Massimo Tabaton; Gang Liu; Daniel W McKeel; Mark L Cohen; Xinglong Wang; Sandra L Siedlak; Barney E Dwyer; Takaaki Hayashi; et al.

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment.
Journal of Alzheimer's disease : JAD 2010;19(1):363-72.
64.
2010

Steven J Greco; Kathryn J Bryan; Sraboni Sarkar; Xiongwei Zhu; Mark A Smith; J Wesson Ashford; Jane M Johnston; Nikolaos Tezapsidis; Gemma Casadesus

Leptin reduces pathology and improves memory in a transgenic mouse model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(4):1155-67.
65.
2010

Xinglong Wang; George Perry; Mark A Smith; Xiongwei Zhu

Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons.
Neuro-degenerative diseases 2010;7(1-3):56-9.
66.
2010

Renato X Santos; Sónia C Correia; Xinglong Wang; George Perry; Mark A Smith; Paula I Moreira; Xiongwei Zhu

A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;20 Suppl 2():S401-12.
67.
2010

Sónia C Correia; Renato X Santos; George Perry; Xiongwei Zhu; Paula I Moreira; Mark A Smith

Mitochondria: the missing link between preconditioning and neuroprotection.
Journal of Alzheimer's disease : JAD 2010;20 Suppl 2():S475-85.
68.
2010

Renato X Santos; Sónia C Correia; Xinglong Wang; George Perry; Mark A Smith; Paula I Moreira; Xiongwei Zhu

Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.
International journal of clinical and experimental pathology 2010;3(6):570-81.
69.
2010

David J Bonda; Maneesh Mailankot; Jeremy G Stone; Matthew R Garrett; Magdalena Staniszewska; Rudy J Castellani; Sandra L Siedlak; Xiongwei Zhu; Hyoung-gon Lee; George Perry; et al.

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.
Redox report : communications in free radical research 2010;15(4):161-8.
70.
2010

Sónia C Correia; Cristina Carvalho; Susana Cardoso; Renato X Santos; Maria S Santos; Catarina R Oliveira; George Perry; Xiongwei Zhu; Mark A Smith; Paula I Moreira

Mitochondrial preconditioning: a potential neuroprotective strategy.
Frontiers in aging neuroscience 2010;2():.
71.
2010

David J Bonda; Hyun-pil Lee; Wataru Kudo; Xiongwei Zhu; Mark A Smith; Hyoung-gon Lee

Pathological implications of cell cycle re-entry in Alzheimer disease.
Expert reviews in molecular medicine 2010;12():e19.
72.
2010

Massimo Tabaton; Xiongwei Zhu; George Perry; Mark A Smith; Luca Giliberto

Signaling effect of amyloid-beta(42) on the processing of AbetaPP.
Experimental neurology 2010;221(1):18-25.
73.
2010

Bo Su; Xinglong Wang; Ling Zheng; George Perry; Mark A Smith; Xiongwei Zhu

Abnormal mitochondrial dynamics and neurodegenerative diseases.
Biochimica et biophysica acta 2010;1802(1):135-42.
74.
2010

Paula I Moreira; Xiongwei Zhu; Xinglong Wang; Hyoung-Gon Lee; Akihiko Nunomura; Robert B Petersen; George Perry; Mark A Smith

Mitochondria: a therapeutic target in neurodegeneration.
Biochimica et biophysica acta 2010;1802(1):212-20.
75.
2010

Paula I Moreira; Cristina Carvalho; Xiongwei Zhu; Mark A Smith; George Perry

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology.
Biochimica et biophysica acta 2010;1802(1):2-10.
76.
2009

George Perry; Paula I Moreira; Sandra L Siedlak; Akihiko Nunomura; Xiongwei Zhu; Mark A Smith

Natural oxidant balance in Parkinson disease.
Archives of neurology 2009;66(12):1445.
77.
2009

Hyun-Pil Lee; Gemma Casadesus; Xiongwei Zhu; Hyoung-gon Lee; George Perry; Mark A Smith; Katarzyna Gustaw-Rothenberg; Alan Lerner

All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease.
Expert review of neurotherapeutics 2009;9(11):1615-21.
78.
2009

Cristina Carvalho; Sónia C Correia; Renato X Santos; Susana Cardoso; Paula I Moreira; Timothy A Clark; Xiongwei Zhu; Mark A Smith; George Perry

Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia.
Journal of bioenergetics and biomembranes 2009;41(5):433-40.
79.
2009

Barney E Dwyer; Meghan L Stone; Nadia Gorman; Peter R Sinclair; George Perry; Mark A Smith; Xiongwei Zhu

Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease.
Neuroscience letters 2009;461(3):302-5.
80.
2009

Barney E Dwyer; Mark A Smith; Sandy L Richardson; George Perry; Xiongwei Zhu

Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease.
Neuroscience letters 2009;460(2):180-4.
81.
2009

Xinglong Wang; Bo Su; Hyoung-gon Lee; Xinyi Li; George Perry; Mark A Smith; Xiongwei Zhu

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(28):9090-103.
82.
2009

Mar Perez; Ismael Santa-Maria; Elena Gomez de Barreda; Xiongwei Zhu; Raquel Cuadros; Jose Roman Cabrero; Francisco Sanchez-Madrid; Hana N Dawson; Michael P Vitek; George Perry; et al.

Tau--an inhibitor of deacetylase HDAC6 function.
Journal of neurochemistry 2009;109(6):1756-66.
83.
2009

Steven J Greco; Sraboni Sarkar; Gemma Casadesus; Xiongwei Zhu; Mark A Smith; J Wesson Ashford; Jane M Johnston; Nikolaos Tezapsidis

Leptin inhibits glycogen synthase kinase-3beta to prevent tau phosphorylation in neuronal cells.
Neuroscience letters 2009;455(3):191-4.
84.
2009

Xinglong Wang; Bo Su; Ling Zheng; George Perry; Mark A Smith; Xiongwei Zhu

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.
Journal of neurochemistry 2009;109 Suppl 1():153-9.
85.
2009

Barney E Dwyer; Leo R Zacharski; Dominic J Balestra; Alan J Lerner; George Perry; Xiongwei Zhu; Mark A Smith

Getting the iron out: phlebotomy for Alzheimer's disease?
Medical hypotheses 2009;72(5):504-9.
86.
2009

Luca Giliberto; Roberta Borghi; Alessandra Piccini; Rosa Mangerini; Sandro Sorbi; Gabriella Cirmena; Anna Garuti; Bernardino Ghetti; Fabrizio Tagliavini; Mohamed R Mughal; et al.

Mutant presenilin 1 increases the expression and activity of BACE1.
The Journal of biological chemistry 2009;284(14):9027-38.
87.
2009

Marta Tajes; Marc Yeste-Velasco; Xiongwei Zhu; Steven P Chou; Mark A Smith; Mercè Pallàs; Antoni Camins; Gemma Casadesús

Activation of Akt by lithium: pro-survival pathways in aging.
Mechanisms of ageing and development 2009;130(4):253-61.
88.
2009

Hyoung-gon Lee; Gemma Casadesus; Akihiko Nunomura; Xiongwei Zhu; Rudy J Castellani; Sandy L Richardson; George Perry; Dean W Felsher; Robert B Petersen; Mark A Smith

The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse.
The American journal of pathology 2009;174(3):891-7.
89.
2009

Hyun-Pil Lee; Xiaochun Zhu; Xiongwei Zhu; S Chad Skidmore; George Perry; Lawrence M Sayre; Mark A Smith; Hyoung-Gon Lee

The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells.
Journal of neurochemistry 2009;108(6):1434-41.
90.
2009

Rudy J Castellani; Xiongwei Zhu; Hyoung-Gon Lee; Mark A Smith; George Perry

Molecular pathogenesis of Alzheimer's disease: Reductionist versus expansionist approaches.
International journal of molecular sciences 2009;10(3):1386-406.
91.
2009

Hyoung-Gon Lee; Gemma Casadesus; Xiongwei Zhu; Rudy J Castellani; Andrew McShea; George Perry; Robert B Petersen; Vladan Bajic; Mark A Smith

Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease.
Neurochemistry international 2009;54(2):84-8.
92.
2009

Emma Ramiro-Puig; Gemma Casadesús; Hyoung-gon Lee; Xiongwei Zhu; Andrew McShea; George Perry; Francisco J Pérez-Cano; Mark A Smith; Margarida Castell

Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress.
European journal of nutrition 2009;48(1):54-61.
93.
2009

George Perry; Xiongwei Zhu; Paula I Moreira; Mark A Smith

Altered redox balance in disease: can we change the new equilibria?
Annals of neurology 2009;65(2):121-3.
94.
2009

Hyoung-gon Lee; Xiongwei Zhu; Gemma Casadesus; Mercé Pallàs; Antoni Camins; Michael J O'Neill; Shigetada Nakanishi; George Perry; Mark A Smith

The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival.
Brain research 2009;1249():244-50.
95.
2009

Nikolaos Tezapsidis; Jane M Johnston; Mark A Smith; J Wesson Ashford; Gemma Casadesus; Nikolaos K Robakis; Benjamin Wolozin; George Perry; Xiongwei Zhu; Steven J Greco; et al.

Leptin: a novel therapeutic strategy for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(4):731-40.
96.
2009

V Prakash Reddy; Xiongwei Zhu; George Perry; Mark A Smith

Oxidative stress in diabetes and Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;16(4):763-74.
97.
2009

Susana Cardoso; Sónia Correia; Renato X Santos; Cristina Carvalho; Maria S Santos; Catarina R Oliveira; George Perry; Mark A Smith; Xiongwei Zhu; Paula I Moreira

Insulin is a two-edged knife on the brain.
Journal of Alzheimer's disease : JAD 2009;18(3):483-507.
98.
2009

Rudy J Castellani; Hyoung-gon Lee; Sandra L Siedlak; Akihiko Nunomura; Takaaki Hayashi; Masao Nakamura; Xiongwei Zhu; George Perry; Mark A Smith

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.
Journal of Alzheimer's disease : JAD 2009;18(2):447-52.
99.
2009

Bo Su; Haihua Liu; Xinglong Wang; Shu G Chen; Sandra L Siedlak; Eisaku Kondo; Raymond Choi; Atsushi Takeda; Rudy J Castellani; George Perry; et al.

Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease.
Molecular neurodegeneration 2009;4():32.
100.
2009

Hyoung-gon Lee; Qun Chen; Julie A Wolfram; Sandy L Richardson; Anna Liner; Sandra L Siedlak; Xiongwei Zhu; Nicholas P Ziats; Hisashi Fujioka; Dean W Felsher; et al.

Cell cycle re-entry and mitochondrial defects in myc-mediated hypertrophic cardiomyopathy and heart failure.
PloS one 2009;4(9):e7172.
101.
2009

Avi L Friedlich; Raj K Rolston; Xiongwei Zhu; Michael W Marlatt; Rudy J Castellani; Akihiko Nunomura; Hyoung-Gon Lee; Gemma Casadesus; George Perry; Mark A Smith

Treatment advances in Alzheimer's disease based on the oxidative stress model.
F1000 medicine reports 2009;1():.
102.
2008

Xinglong Wang; Bo Su; Sandra L Siedlak; Paula I Moreira; Hisashi Fujioka; Yang Wang; Gemma Casadesus; Xiongwei Zhu

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(49):19318-23.
103.
2008

B Su; X Wang; A Nunomura; P I Moreira; H-gon Lee; G Perry; M A Smith; X Zhu

Oxidative stress signaling in Alzheimer's disease.
Current Alzheimer research 2008;5(6):525-32.
104.
2008

Na-Hye Myung; Xiongwei Zhu; Inna I Kruman; Rudy J Castellani; Robert B Petersen; Sandra L Siedlak; George Perry; Mark A Smith; Hyoung-gon Lee

Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes.
Age (Dordrecht, Netherlands) 2008;30(4):209-15.
105.
2008

Steven J Greco; Sraboni Sarkar; Jane M Johnston; Xiongwei Zhu; Bo Su; Gemma Casadesus; J Wesson Ashford; Mark A Smith; Nikolaos Tezapsidis

Leptin reduces Alzheimer's disease-related tau phosphorylation in neuronal cells.
Biochemical and biophysical research communications 2008;376(3):536-41.
106.
2008

Gjumrakch Aliev; Mark E Obrenovich; V Prakash Reddy; Justin C Shenk; Paula I Moreira; Akihiko Nunomura; Xiongwei Zhu; Mark A Smith; George Perry

Antioxidant therapy in Alzheimer's disease: theory and practice.
Mini reviews in medicinal chemistry 2008;8(13):1395-406.
107.
2008

E K Larkin; S R Patel; R C Elston; C Gray-McGuire; X Zhu; S Redline

Using linkage analysis to identify quantitative trait loci for sleep apnea in relationship to body mass index.
Annals of human genetics 2008;72(Pt 6):762-73.
108.
2008

Michael W Marlatt; Paul J Lucassen; George Perry; Mark A Smith; Xiongwei Zhu

Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies.
Journal of Alzheimer's disease : JAD 2008;15(2):199-210.
109.
2008

X Zhu; S L Siedlak; Y Wang; G Perry; R J Castellani; M L Cohen; M A Smith

Neuronal binucleation in Alzheimer disease hippocampus.
Neuropathology and applied neurobiology 2008;34(4):457-65.
110.
2008

Katarzyna A Gustaw; Matthew R Garrett; Hyoung-Gon Lee; Rudy J Castellani; Michael G Zagorski; Annamalai Prakasam; Sandra L Siedlak; Xiongwei Zhu; George Perry; Robert B Petersen; et al.

Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis.
Journal of neurochemistry 2008;106(3):1350-6.
111.
2008

Xinglong Wang; Bo Su; Hisashi Fujioka; Xiongwei Zhu

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.
The American journal of pathology 2008;173(2):470-82.
112.
2008

Rudy J Castellani; Hyoung-Gon Lee; Xiongwei Zhu; George Perry; Mark A Smith

Alzheimer disease pathology as a host response.
Journal of neuropathology and experimental neurology 2008;67(6):523-31.
113.
2008

Payal N Gandhi; Xinglong Wang; Xiongwei Zhu; Shu G Chen; Amy L Wilson-Delfosse

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules.
Journal of neuroscience research 2008;86(8):1711-20.
114.
2008

Bo Su; Xinglong Wang; Kelly L Drew; George Perry; Mark A Smith; Xiongwei Zhu

Physiological regulation of tau phosphorylation during hibernation.
Journal of neurochemistry 2008;105(6):2098-108.
115.
2008

Y Wu; X Wang; X Mo; Z Xi; F Xiao; J Li; X Zhu; G Luan; Y Wang; Y Li; et al.

Expression of monocyte chemoattractant protein-1 in brain tissue of patients with intractable epilepsy.
Clinical neuropathology 2008;27(2):55-63.
116.
2008

Paula I Moreira; Maria S Santos; Catarina R Oliveira; Justin C Shenk; Akihiko Nunomura; Mark A Smith; Xiongwei Zhu; George Perry

Alzheimer disease and the role of free radicals in the pathogenesis of the disease.
CNS & neurological disorders drug targets 2008;7(1):3-10.
117.
2008

Elena Tamagno; Michela Guglielmotto; Manuela Aragno; Roberta Borghi; Riccardo Autelli; Luca Giliberto; Giuseppe Muraca; Oliviero Danni; Xiongwei Zhu; Mark A Smith; et al.

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
Journal of neurochemistry 2008;104(3):683-95.
118.
2008

Daniel J Klionsky; Hagai Abeliovich; Patrizia Agostinis; Devendra K Agrawal; Gjumrakch Aliev; David S Askew; Misuzu Baba; Eric H Baehrecke; Ben A Bahr; Andrea Ballabio; et al.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Autophagy 2008;4(2):151-75.
119.
2008

George Perry; Xiongwei Zhu; Asim K Babar; Sandra L Siedlak; Qiwei Yang; Genta Ito; Takeshi Iwatsubo; Mark A Smith; Shu G Chen

Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies.
Neuro-degenerative diseases 2008;5(3-4):222-4.
120.
2008

Akanksha Thakur; Sandra L Siedlak; Sheronica L James; David J Bonda; Akanksha Rao; Kate M Webber; Antoni Camins; Mercé Pallàs; Gemma Casadesus; Hyoung-Gon Lee; et al.

Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease.
International journal of clinical and experimental pathology 2008;1(2):134-46.
121.
2008

George Perry; Rudy J Castellani; Paula I Moreira; Hyoung-Gon Lee; Xiongwei Zhu; Mark A Smith

Pathology's new role: defining disease process and protective responses.
International journal of clinical and experimental pathology 2008;1(1):1-4.
122.
2008

Kathryn J Bryan; Xiongwei Zhu; Peggy L Harris; George Perry; Rudy J Castellani; Mark A Smith; Gemma Casadesus

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease.
Molecular neurodegeneration 2008;3():13.
123.
2007

Xinglong Wang; Bo Su; George Perry; Mark A Smith; Xiongwei Zhu

Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease.
Free radical biology & medicine 2007;43(12):1569-73.
124.
2007

A Nunomura; P I Moreira; H G Lee; X Zhu; R J Castellani; M A Smith; G Perry

Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases.
CNS & neurological disorders drug targets 2007;6(6):411-23.
125.
2007

Paula I Moreira; Sandra L Siedlak; Xinglong Wang; Maria S Santos; Catarina R Oliveira; Massimo Tabaton; Akihiko Nunomura; Luke I Szweda; Gjumrakch Aliev; Mark A Smith; et al.

Increased autophagic degradation of mitochondria in Alzheimer disease.
Autophagy 2007;3(6):614-5.
126.
2007

Rudy J Castellani; Paula I Moreira; Gang Liu; Jon Dobson; George Perry; Mark A Smith; Xiongwei Zhu

Iron: the Redox-active center of oxidative stress in Alzheimer disease.
Neurochemical research 2007;32(10):1640-5.
127.
2007

Paula I Moreira; Peggy L R Harris; Xiongwei Zhu; Maria S Santos; Catarina R Oliveira; Mark A Smith; George Perry

Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts.
Journal of Alzheimer's disease : JAD 2007;12(2):195-206.
128.
2007

X Zhu; B Su; X Wang; M A Smith; G Perry

Causes of oxidative stress in Alzheimer disease.
Cellular and molecular life sciences : CMLS 2007;64(17):2202-10.
129.
2007

Jie Li; Xuechun Xia; Yibao Ke; Huiling Nie; Mark A Smith; Xiongwei Zhu

Trichosanthin induced apoptosis in HL-60 cells via mitochondrial and endoplasmic reticulum stress signaling pathways.
Biochimica et biophysica acta 2007;1770(8):1169-80.
130.
2007

Xiongwei Zhu; Mark A Smith; Kazuhiro Honda; Gjumrakch Aliev; Paula I Moreira; Akihiko Nunomura; Gemma Casadesus; Peggy L R Harris; Sandra L Siedlak; George Perry

Vascular oxidative stress in Alzheimer disease.
Journal of the neurological sciences 2007;257(1-2):240-6.
131.
2007

Akanksha Thakur; Xinglong Wang; Sandra L Siedlak; George Perry; Mark A Smith; Xiongwei Zhu

c-Jun phosphorylation in Alzheimer disease.
Journal of neuroscience research 2007;85(8):1668-73.
132.
2007

Hyoung-gon Lee; Xiongwei Zhu; Rudy J Castellani; Akihiko Nunomura; George Perry; Mark A Smith

Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses.
The Journal of pharmacology and experimental therapeutics 2007;321(3):823-9.
133.
2007

Paula I Moreira; Sandra L Siedlak; Xinglong Wang; Maria S Santos; Catarina R Oliveira; Massimo Tabaton; Akihiko Nunomura; Luke I Szweda; Gjumrakch Aliev; Mark A Smith; et al.

Autophagocytosis of mitochondria is prominent in Alzheimer disease.
Journal of neuropathology and experimental neurology 2007;66(6):525-32.
134.
2007

Xiongwei Zhu; Jesus Avila; George Perry; Mark A Smith

Treating the lesions, not the disease.
The American journal of pathology 2007;170(5):1457-9.
135.
2007

Rudy J Castellani; Xiongwei Zhu; Hyoung-gon Lee; Paula I Moreira; George Perry; Mark A Smith

Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees?
Expert review of neurotherapeutics 2007;7(5):473-85.
136.
2007

Robert B Petersen; Akihiko Nunomura; Hyoung-gon Lee; Gemma Casadesus; George Perry; Mark A Smith; Xiongwei Zhu

Signal transduction cascades associated with oxidative stress in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(2):143-52.
137.
2007

Xiongwei Zhu; Hyoung-gon Lee; George Perry; Mark A Smith

Alzheimer disease, the two-hit hypothesis: an update.
Biochimica et biophysica acta 2007;1772(4):494-502.
138.
2007

Laura A Previll; Meredith E Crosby; Rudy J Castellani; Robert Bowser; George Perry; Mark A Smith; Xiongwei Zhu

Increased expression of p130 in Alzheimer disease.
Neurochemical research 2007;32(4-5):639-44.
139.
2007

Quan Liu; Fang Xie; Raj Rolston; Paula I Moreira; Akihiko Nunomura; Xiongwei Zhu; Mark A Smith; George Perry

Prevention and treatment of Alzheimer disease and aging: antioxidants.
Mini reviews in medicinal chemistry 2007;7(2):171-80.
140.
2007

Teresa A Evans; Arun K Raina; André Delacourte; Olga Aprelikova; Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A Smith

BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease.
International journal of medical sciences 2007;4(3):140-5.
141.
2007

Gemma Casadesus; Mark A Smith; Samar Basu; Jing Hua; Dae E Capobianco; Sandra L Siedlak; Xiongwei Zhu; George Perry

Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease.
Molecular neurodegeneration 2007;2():2.
142.
2007

Jie Li; Xuechun Xia; Huiling Nie; Mark A Smith; Xiongwei Zhu

PKC inhibition is involved in trichosanthin-induced apoptosis in human chronic myeloid leukemia cell line K562.
Biochimica et biophysica acta 2007;1770(1):63-70.
143.
2006

Hyoung-gon Lee; Masumi Ueda; Yoichi Miyamoto; Yoshihiro Yoneda; George Perry; Mark A Smith; Xiongwei Zhu

Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease.
Brain research 2006;1124(1):1-4.
144.
2006

Hyoung-gon Lee; Masumi Ueda; Xiongwei Zhu; George Perry; Mark A Smith

Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway?
Journal of neuroscience research 2006;84(8):1856-61.
145.
2006

Matthew Mei; Bo Su; Kristen Harrison; Mark Chao; Sandra L Siedlak; Laura A Previll; LaMia Jackson; Dan X Cai; Xiongwei Zhu

Distribution, levels and phosphorylation of Raf-1 in Alzheimer's disease.
Journal of neurochemistry 2006;99(5):1377-88.
146.
2006

Xiongwei Zhu; Sandra L Siedlak; Mark A Smith; George Perry; Shu G Chen

LRRK2 protein is a component of Lewy bodies.
Annals of neurology 2006;60(5):617-8; author reply 618-9.
147.
2006

Xiongwei Zhu; Arun K Raina; George Perry; Mark A Smith

Apoptosis in Alzheimer disease: a mathematical improbability.
Current Alzheimer research 2006;3(4):393-6.
148.
2006

Hyoung-gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A Smith

Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!
The American journal of pathology 2006;169(3):738-9.
149.
2006

Hyoung-gon Lee; George Perry; Xiongwei Zhu; Akihiko Nunomura; Mark A Smith

Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression".
Free radical biology & medicine 2006;41(2):188-9.
150.
2006

Akihiko Nunomura; Rudy J Castellani; Xiongwei Zhu; Paula I Moreira; George Perry; Mark A Smith

Involvement of oxidative stress in Alzheimer disease.
Journal of neuropathology and experimental neurology 2006;65(7):631-41.
151.
2006

Xiongwei Zhu; George Perry; Paula I Moreira; Gjumrakch Aliev; Adam D Cash; Keisuke Hirai; Mark A Smith

Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease.
Journal of Alzheimer's disease : JAD 2006;9(2):147-53.
152.
2006

Hyoung-gon Lee; Xiongwei Zhu; Atsushi Takeda; George Perry; Mark A Smith

Emerging evidence for the neuroprotective role of alpha-synuclein.
Experimental neurology 2006;200(1):1-7.
153.
2006

Paula I Moreira; Xiongwei Zhu; Akihiko Nunomura; Mark A Smith; George Perry

Therapeutic options in Alzheimer's disease.
Expert review of neurotherapeutics 2006;6(6):897-910.
154.
2006

Rudy J Castellani; Hyoung-Gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A Smith

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic.
Acta neuropathologica 2006;111(6):503-9.
155.
2006

Paula I Moreira; Xiongwei Zhu; Hyoung-Gon Lee; Kazuhiro Honda; Mark A Smith; George Perry

The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease.
Mechanisms of ageing and development 2006;127(6):501-6.
156.
2006

Akihiko Nunomura; Rudy J Castellani; Hyoung-Gon Lee; Paula I Moreira; Xiongwei Zhu; George Perry; Mark A Smith

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream.
Science of aging knowledge environment : SAGE KE 2006;2006(8):pe10.
157.
2006

Xiongwei Zhu; Hyoung-Gon Lee; Paula I Moreira; Mark A Smith; George Perry

Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice".
Free radical biology & medicine 2006;40(5):737-9.
158.
2006

Mark A Smith; Xiongwei Zhu; Hyoung-Gon Lee; Peggy L R Harris; Anne E Fortino; George Perry; Rudy J Castellani

Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy.
Age (Dordrecht, Netherlands) 2006;28(1):85-91.
159.
2006

Hyoung-gon Lee; Xiongwei Zhu; Akihiko Nunomura; George Perry; Mark A Smith

Amyloid beta: the alternate hypothesis.
Current Alzheimer research 2006;3(1):75-80.
160.
2006

P I Moreira; K Honda; X Zhu; A Nunomura; G Casadesus; M A Smith; G Perry

Brain and brawn: parallels in oxidative strength.
Neurology 2006;66(2 Suppl 1):S97-101.
161.
2006

Kate M Webber; Gemma Casadesus; Xiongwei Zhu; Mark E Obrenovich; Craig S Atwood; George Perry; Richard L Bowen; Mark A Smith

The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target.
Current pharmaceutical design 2006;12(6):691-7.
162.
2006

Hyoung-gon Lee; Xiongwei Zhu; George Perry; Mark A Smith

The fallacy of amyloid and cognition in Alzheimer's disease.
Drugs & aging 2006;23(2):179.
163.
2006

Paula I Moreira; Xiongwei Zhu; Quan Liu; Kazuhiro Honda; Sandra L Siedlak; Peggy L Harris; Mark A Smith; George Perry

Compensatory responses induced by oxidative stress in Alzheimer disease.
Biological research 2006;39(1):7-13.
164.
2006

Kate M Webber; Douglas M Stocco; Gemma Casadesus; Richard L Bowen; Craig S Atwood; Laura A Previll; Peggy L R Harris; Xiongwei Zhu; George Perry; Mark A Smith

Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease.
Molecular neurodegeneration 2006;1():14.
165.
2006

Barney E Dwyer; Meghan L Stone; Xiongwei Zhu; George Perry; Mark A Smith

Heme deficiency in Alzheimer's disease: a possible connection to porphyria.
Journal of biomedicine & biotechnology 2006;2006(3):24038.
166.
2006

Mark A Smith; George Perry; Xiongwei Zhu; Abdelali Haoudi

Neurodegenerative diseases: mechanisms and therapies.
Journal of biomedicine & biotechnology 2006;2006(3):47539.
167.
2006

Akihiko Nunomura; Kazuhiro Honda; Atsushi Takeda; Keisuke Hirai; Xiongwei Zhu; Mark A Smith; George Perry

Oxidative damage to RNA in neurodegenerative diseases.
Journal of biomedicine & biotechnology 2006;2006(3):82323.
168.
2006

Xiongwei Zhu; Asim Babar; Sandra L Siedlak; Qiwei Yang; Genta Ito; Takeshi Iwatsubo; Mark A Smith; George Perry; Shu G Chen

LRRK2 in Parkinson's disease and dementia with Lewy bodies.
Molecular neurodegeneration 2006;1():17.
169.
2005

Yi Long Ma; Xiongwei Zhu; Patricia M Rivera; Øivind Tøien; Brian M Barnes; Joseph C LaManna; Mark A Smith; Kelly L Drew

Absence of cellular stress in brain after hypoxia induced by arousal from hibernation in Arctic ground squirrels.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;289(5):R1297-306.
170.
2005

Kate M Webber; Arun K Raina; Michael W Marlatt; Xiongwei Zhu; María I Prat; Laura Morelli; Gemma Casadesus; George Perry; Mark A Smith

The cell cycle in Alzheimer disease: a unique target for neuropharmacology.
Mechanisms of ageing and development 2005;126(10):1019-25.
171.
2005

Paula I Moreira; Kazuhiro Honda; Quan Liu; Maria S Santos; Catarina R Oliveira; Gjumrakch Aliev; Akihiko Nunomura; Xiongwei Zhu; Mark A Smith; George Perry

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology.
Current Alzheimer research 2005;2(4):403-8.
172.
2005

Gang Liu; Matthew R Garrett; Ping Men; Xiongwei Zhu; George Perry; Mark A Smith

Nanoparticle and other metal chelation therapeutics in Alzheimer disease.
Biochimica et biophysica acta 2005;1741(3):246-52.
173.
2005

Xiongwei Zhu; Paula I Moreira; Mark A Smith; George Perry

Alzheimer's disease: an intracellular movement disorder?
Trends in molecular medicine 2005;11(9):391-3.
174.
2005

Barney E Dwyer; Atsushi Takeda; Xiongwei Zhu; George Perry; Mark A Smith

Ferric cycle activity and Alzheimer disease.
Current neurovascular research 2005;2(3):261-7.
175.
2005

P I Moreira; S L Siedlak; G Aliev; X Zhu; A D Cash; M A Smith; G Perry

Oxidative stress mechanisms and potential therapeutics in Alzheimer disease.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(7):921-32.
176.
2005

Xiongwei Zhu; Mark A Smith; George Perry; Yang Wang; Austin P Ross; Huiwen W Zhao; Joseph C Lamanna; Kelly L Drew

MAPKs are differentially modulated in arctic ground squirrels during hibernation.
Journal of neuroscience research 2005;80(6):862-8.
177.
2005

Kazuhiro Honda; Mark A Smith; Xiongwei Zhu; Diane Baus; William C Merrick; Alan M Tartakoff; Thomas Hattier; Peggy L Harris; Sandra L Siedlak; Hisashi Fujioka; et al.

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron.
The Journal of biological chemistry 2005;280(22):20978-86.
178.
2005

Hyoung-Gon Lee; Rudy J Castellani; Xiongwei Zhu; George Perry; Mark A Smith

Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective?
International journal of experimental pathology 2005;86(3):133-8.
179.
2005

Paula I Moreira; Mark A Smith; Xiongwei Zhu; Akihiko Nunomura; Rudy J Castellani; George Perry

Oxidative stress and neurodegeneration.
Annals of the New York Academy of Sciences 2005;1043():545-52.
180.
2005

Xiongwei Zhu; Matthew Mei; Hyoung-Gon Lee; Yang Wang; Jiahuai Han; George Perry; Mark A Smith

P38 activation mediates amyloid-beta cytotoxicity.
Neurochemical research 2005;30(6-7):791-6.
181.
2005

Mark A Smith; Akihiko Nunomura; Hyoung-gon Lee; Xiongwei Zhu; Paula I Moreira; Jesús Avila; George Perry

Chronological primacy of oxidative stress in Alzheimer disease.
Neurobiology of aging 2005;26(5):579-80.
182.
2005

Hyoung-Gon Lee; George Perry; Paula I Moreira; Matthew R Garrett; Quan Liu; Xiongwei Zhu; Atsushi Takeda; Akihiko Nunomura; Mark A Smith

Tau phosphorylation in Alzheimer's disease: pathogen or protector?
Trends in molecular medicine 2005;11(4):164-9.
183.
2005

Paula I Moreira; Catarina R Oliveira; Maria S Santos; Akihiko Nunomura; Kazuhiro Honda; Xiongwei Zhu; Mark A Smith; George Perry

A second look into the oxidant mechanisms in Alzheimer's disease.
Current neurovascular research 2005;2(2):179-84.
184.
2005

Quan Liu; Mark A Smith; Jesus Avilá; John DeBernardis; Mayank Kansal; Atsushi Takeda; Xiongwei Zhu; Akihiko Nunomura; Kazuhiro Honda; Paula I Moreira; et al.

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations.
Free radical biology & medicine 2005;38(6):746-54.
185.
2005

Kate M Webber; Mark A Smith; Hyoung-gon Lee; Peggy L Harris; Paula Moreira; George Perry; Xiongwei Zhu

Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease.
Journal of neuroscience research 2005;79(4):554-60.
186.
2005

G Casadesus; C S Atwood; X Zhu; A W Hartzler; K M Webber; G Perry; R L Bowen; M A Smith

Evidence for the role of gonadotropin hormones in the development of Alzheimer disease.
Cellular and molecular life sciences : CMLS 2005;62(3):293-8.
187.
2005

Xiongwei Zhu; George Perry; Mark A Smith

Insulin signaling, diabetes mellitus and risk of Alzheimer disease.
Journal of Alzheimer's disease : JAD 2005;7(1):81-4.
188.
2005

Quan Liu; Hyoung-gon Lee; Kazuhiro Honda; Sandra L Siedlak; Peggy L R Harris; Adam D Cash; Xiongwei Zhu; Jesús Avila; Akihiko Nunomura; Atsushi Takeda; et al.

Tau modifiers as therapeutic targets for Alzheimer's disease.
Biochimica et biophysica acta 2005;1739(2-3):211-5.
189.
2005

Paula I Moreira; Mark A Smith; Xiongwei Zhu; Kazuhiro Honda; Hyoung-Gon Lee; Gjumrakch Aliev; George Perry

Oxidative damage and Alzheimer's disease: are antioxidant therapies useful?
Drug news & perspectives 2005;18(1):13-9.
190.
2005

Xiongwei Zhu; Hyoung-Gon Lee; Gemma Casadesus; Jesus Avila; Kelly Drew; George Perry; Mark A Smith

Oxidative imbalance in Alzheimer's disease.
Molecular neurobiology 2005;31(1-3):205-17.
191.
2005

Michael W Marlatt; Kate M Webber; Paula I Moreira; Hyoung-gon Lee; Gemma Casadesus; Kazuhiro Honda; Xiongwei Zhu; George Perry; Mark A Smith

Therapeutic opportunities in Alzheimer disease: one for all or all for one?
Current medicinal chemistry 2005;12(10):1137-47.
192.
2004

Hyoung-Gon Lee; Paula I Moreira; Xiongwei Zhu; Mark A Smith; George Perry

Staying connected: synapses in Alzheimer disease.
The American journal of pathology 2004;165(5):1461-4.
193.
2004

Paula I Moreira; Mark A Smith; Xiongwei Zhu; Maria S Santos; Catarina R Oliveira; George Perry

Therapeutic potential of oxidant mechanisms in Alzheimer's disease.
Expert review of neurotherapeutics 2004;4(6):995-1004.
194.
2004

Xiongwei Zhu; Mark A Smith; George Perry; Gjumrakch Aliev

Mitochondrial failures in Alzheimer's disease.
American journal of Alzheimer's disease and other dementias 2004;19(6):345-52.
195.
2004

Atsushi Takeda; Yasuto Itoyama; Teiko Kimpara; Xiongwei Zhu; Jesús Avila; Barney E Dwyer; George Perry; Mark A Smith

Heme catabolism and heme oxygenase in neurodegenerative disease.
Antioxidants & redox signaling 2004;6(5):888-94.
196.
2004

Gemma Casadesus; Barbara Shukitt-Hale; Heather M Stellwagen; Xiongwei Zhu; Hyoung-Gon Lee; Mark A Smith; James A Joseph

Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats.
Nutritional neuroscience 2004;7(5-6):309-16.
197.
2004

Yi Long Ma; Margaret E Rice; Mei Lan Chao; Patricia M Rivera; Huiwen W Zhao; Austin P Ross; Xiongwei Zhu; Mark A Smith; Kelly L Drew

Ascorbate distribution during hibernation is independent of ascorbate redox state.
Free radical biology & medicine 2004;37(4):511-20.
198.
2004

X Zhu; K M Webber; G Casadesus; A K Raina; H G Lee; M Marlatt; A Hartzler; C S Atwood; G Perry; M A Smith

Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities.
Current drug targets 2004;5(6):559-63.
199.
2004

K L Drew; M B Harris; J C LaManna; M A Smith; X W Zhu; Y L Ma

Hypoxia tolerance in mammalian heterotherms.
The Journal of experimental biology 2004;207(Pt 18):3155-62.
200.
2004

Gemma Casadesus; Xiongwei Zhu; Craig S Atwood; Kate M Webber; George Perry; Richard L Bowen; Mark A Smith

Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease.
Current drug targets. CNS and neurological disorders 2004;3(4):281-5.
201.
2004

Rudy J Castellani; Kazuhiro Honda; Xiongwei Zhu; Adam D Cash; Akihiko Nunomura; George Perry; Mark A Smith

Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease.
Ageing research reviews 2004;3(3):319-26.
202.
2004

Hyoung-Gon Lee; Gemma Casadesus; Xiongwei Zhu; Atsushi Takeda; George Perry; Mark A Smith

Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease.
Annals of the New York Academy of Sciences 2004;1019():1-4.
203.
2004

Xiongwei Zhu; Yang Wang; Osamu Ogawa; Hyoung-gon Lee; Arun K Raina; Sandra L Siedlak; Peggy L R Harris; Hisashi Fujioka; Shun Shimohama; Massimo Tabaton; et al.

Neuroprotective properties of Bcl-w in Alzheimer disease.
Journal of neurochemistry 2004;89(5):1233-40.
204.
2004

Xiongwei Zhu; Arun K Raina; George Perry; Mark A Smith

Alzheimer's disease: the two-hit hypothesis.
Lancet neurology 2004;3(4):219-26.
205.
2004

Hyoung-gon Lee; Gemma Casadesus; Xiongwei Zhu; James A Joseph; George Perry; Mark A Smith

Perspectives on the amyloid-beta cascade hypothesis.
Journal of Alzheimer's disease : JAD 2004;6(2):137-45.
206.
2004

Gemma Casadesus; Mark A Smith; Xiongwei Zhu; Gjumrakch Aliev; Adam D Cash; Kazuhiro Honda; Robert B Petersen; George Perry

Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species.
Journal of Alzheimer's disease : JAD 2004;6(2):165-9.
207.
2004

Hyoung-gon Lee; Osamu Ogawa; Xiongwei Zhu; Michael J O'Neill; Robert B Petersen; Rudolph J Castellani; Hossein Ghanbari; George Perry; Mark A Smith

Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease.
Acta neuropathologica 2004;107(4):365-71.
208.
2004

Xiongwei Zhu; Arun K Raina; Hyoung-Gon Lee; Gemma Casadesus; Mark A Smith; George Perry

Oxidative stress signalling in Alzheimer's disease.
Brain research 2004;1000(1-2):32-9.
209.
2004

Xiongwei Zhu; Andrew McShea; Peggy L R Harris; Arun K Raina; Rudy J Castellani; Jens Oliver Funk; Sapan Shah; Craig Atwood; Richard Bowen; Robert Bowser; et al.

Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease.
Journal of neuroscience research 2004;75(5):698-703.
210.
2004

Michael Marlatt; Hyoung-gon Lee; George Perry; Mark A Smith; Xiongwei Zhu

Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease.
Acta neurobiologiae experimentalis 2004;64(1):81-7.
211.
2004

Hyoung-gon Lee; Xiongwei Zhu; Michael J O'Neill; Kate Webber; Gemma Casadesus; Michael Marlatt; Arun K Raina; George Perry; Mark A Smith

The role of metabotropic glutamate receptors in Alzheimer's disease.
Acta neurobiologiae experimentalis 2004;64(1):89-98.
212.
2004

Arun K Raina; Xiongwei Zhu; Mark A Smith

Alzheimer's disease and the cell cycle.
Acta neurobiologiae experimentalis 2004;64(1):107-12.
213.
2003

Hyoung-gon Lee; Robert B Petersen; Xiongwei Zhu; Kazuhiro Honda; Gjumrakch Aliev; Mark A Smith; George Perry

Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases?
Brain pathology (Zurich, Switzerland) 2003;13(4):630-8.
214.
2003

Xiongwei Zhu; Arun K Raina; Hyoung-Gon Lee; Mark Chao; Akihiko Nunomura; Massimo Tabaton; Robert B Petersen; George Perry; Mark A Smith

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways.
Antioxidants & redox signaling 2003;5(5):571-6.
215.
2003

Xiongwei Zhu; Zheng Sun; Hyoung-gon Lee; Sandra L Siedlak; George Perry; Mark A Smith

Distribution, levels, and activation of MEK1 in Alzheimer's disease.
Journal of neurochemistry 2003;86(1):136-42.
216.
2003

Osamu Ogawa; Xiongwei Zhu; Hyoung-Gon Lee; Arun Raina; Mark E Obrenovich; Robert Bowser; Hossein A Ghanbari; Rudolph J Castellani; George Perry; Mark A Smith

Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe?
Acta neuropathologica 2003;105(5):524-8.
217.
2003

Adam D Cash; Gjumrakch Aliev; Sandra L Siedlak; Akihiko Nunomura; Hisashi Fujioka; Xiongwei Zhu; Arun K Raina; Harry V Vinters; Massimo Tabaton; Anne B Johnson; et al.

Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation.
The American journal of pathology 2003;162(5):1623-7.
218.
2003

Xiongwei Zhu; Osamu Ogawa; Yang Wang; George Perry; Mark A Smith

JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease.
Journal of neurochemistry 2003;85(1):87-93.
219.
2003

Arun K Raina; Ayala Hochman; Harold Ickes; Xiongwei Zhu; Osamu Ogawa; Adam D Cash; Shun Shimohama; George Perry; Mark A Smith

Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out?
Progress in neuro-psychopharmacology & biological psychiatry 2003;27(2):251-4.
220.
2003

Osamu Ogawa; Hyoung-gon Lee; Xiongwei Zhu; Arun Raina; Peggy L R Harris; Rudolph J Castellani; George Perry; Mark A Smith

Increased p27, an essential component of cell cycle control, in Alzheimer's disease.
Aging cell 2003;2(2):105-10.
221.
2003

Xiongwei Zhu; George Perry; Mark A Smith

Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway.
Redox report : communications in free radical research 2003;8(3):129-33.
222.
2003

Arun K Raina; Xiongwei Zhu; Shun Shimohama; George Perry; Mark A Smith

Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept.
Cell biochemistry and biophysics 2003;39(3):249-55.
223.
2002

George Perry; Akihiko Nunomura; Keisuke Hirai; Xiongwei Zhu; Mar Pérez; Jesús Avila; Rudolph J Castellani; Craig S Atwood; Gjumrakch Aliev; Lawrence M Sayre; et al.

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?
Free radical biology & medicine 2002;33(11):1475-9.
224.
2002

George Perry; Marta A Taddeo; Akihiko Nunomura; Xiongwei Zhu; Tania Zenteno-Savin; Kelly L Drew; Shun Shimohama; Jesús Avila; Rudolph J Castellani; Mark A Smith

Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2002;133(4):507-13.
225.
2002

Osamu Ogawa; Xiongwei Zhu; George Perry; Mark A Smith

Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease.
Science of aging knowledge environment : SAGE KE 2002;2002(41):pe16.
226.
2002

Adam D Cash; George Perry; Osamu Ogawa; Arun K Raina; Xiongwei Zhu; Mark A Smith

Is Alzheimer's disease a mitochondrial disorder?
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2002;8(5):489-96.
227.
2002

Fang Zhou; Joan F Braddock; Yong Hu; Xiongwei Zhu; Rudy J Castellani; Mark A Smith; Kelly L Drew

Microbial origin of glutamate, hibernation and tissue trauma: an in vivo microdialysis study.
Journal of neuroscience methods 2002;119(2):121-8.
228.
2002

Anthony W Hartzler; Xiongwei Zhu; Sandra L Siedlak; Rudolph J Castellani; Jesus Avilá; George Perry; Mark A Smith

The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.
Neurobiology of aging 2002;23(5):855-9.
229.
2002

Xiongwei Zhu; Hyoung-gon Lee; Arun K Raina; George Perry; Mark A Smith

The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
Neuro-Signals 2002;11(5):270-81.
230.
2002

Hyoung-gon Lee; Xiongwei Zhu; Hossein A Ghanbari; Osamu Ogawa; Arun K Raina; Micheal J O'Neill; George Perry; Mark A Smith

Differential regulation of glutamate receptors in Alzheimer's disease.
Neuro-Signals 2002;11(5):282-92.
231.
2002

Mark A Smith; Kelly L Drew; Akihiko Nunomura; Atsushi Takeda; Keisuke Hirai; Xiongwei Zhu; Craig S Atwood; Arun K Raina; Catherine A Rottkamp; Lawrence M Sayre; et al.

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?
Neurochemistry international 2002;40(6):527-31.
232.
2002

Kimberly L Clapp-Lilly; Mark A Smith; George Perry; Peggy L Harris; Xiongwei Zhu; Kelly L Drew; Lawrence K Duffy

Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity.
International journal of circumpolar health 2002;61(1):32-40.
233.
2001

A K Raina; P Pardo; C A Rottkamp; X Zhu; O M Pereira-Smith; M A Smith

Neurons in Alzheimer disease emerge from senescence.
Mechanisms of ageing and development 2001;123(1):3-9.
234.
2001

X Zhu; R J Castellani; A Takeda; A Nunomura; C S Atwood; G Perry; M A Smith

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.
Mechanisms of ageing and development 2001;123(1):39-46.
235.
2001

X Zhu; C A Rottkamp; A Hartzler; Z Sun; A Takeda; H Boux; S Shimohama; G Perry; M A Smith

Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.
Journal of neurochemistry 2001;79(2):311-8.
236.
2001

F Zhou; X Zhu; R J Castellani; R Stimmelmayr; G Perry; M A Smith; K L Drew

Hibernation, a model of neuroprotection.
The American journal of pathology 2001;158(6):2145-51.
237.
2001

K L Clapp-Lilly; M A Smith; G Perry; P L Harris; X Zhu; L K Duffy

Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease.
Neuroreport 2001;12(6):1277-80.
238.
2001

A K Raina; A Hochman; X Zhu; C A Rottkamp; A Nunomura; S L Siedlak; H Boux; R J Castellani; G Perry; M A Smith

Abortive apoptosis in Alzheimer's disease.
Acta neuropathologica 2001;101(4):305-10.
239.
2001

C A Rottkamp; A K Raina; X Zhu; E Gaier; A I Bush; C S Atwood; M Chevion; G Perry; M A Smith

Redox-active iron mediates amyloid-beta toxicity.
Free radical biology & medicine 2001;30(4):447-50.
240.
2001

X Zhu; A K Raina; C A Rottkamp; G Aliev; G Perry; H Boux; M A Smith

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.
Journal of neurochemistry 2001;76(2):435-41.
241.
2001

G Perry; X Zhu; M A Smith

Do neurons have a choice in death?
The American journal of pathology 2001;158(1):1-2.
242.
2000

X Zhu; C A Rottkamp; A K Raina; G J Brewer; H A Ghanbari; H Boux; M A Smith

Neuronal CDK7 in hippocampus is related to aging and Alzheimer disease.
Neurobiology of aging 2000;21(6):807-13.
243.
2000

P L Harris; X Zhu; C Pamies; C A Rottkamp; H A Ghanbari; A McShea; Y Feng; D K Ferris; M A Smith

Neuronal polo-like kinase in Alzheimer disease indicates cell cycle changes.
Neurobiology of aging 2000;21(6):837-41.
244.
2000

X Zhu; C A Rottkamp; H Boux; A Takeda; G Perry; M A Smith

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease.
Journal of neuropathology and experimental neurology 2000;59(10):880-8.
245.
2000

A Takeda; M A Smith; J Avilá; A Nunomura; S L Siedlak; X Zhu; G Perry; L M Sayre

In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification.
Journal of neurochemistry 2000;75(3):1234-41.
246.
2000

A K Raina; X Zhu; C A Rottkamp; M Monteiro; A Takeda; M A Smith

Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease.
Journal of neuroscience research 2000;61(2):128-33.
247.
2000

X Zhu; A K Raina; H Boux; Z L Simmons; A Takeda; M A Smith

Activation of oncogenic pathways in degenerating neurons in Alzheimer disease.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(4-5):433-7.
248.
2000

A K Raina; X Zhu; M Monteiro; A Takeda; M A Smith

Abortive oncogeny and cell cycle-mediated events in Alzheimer disease.
Progress in cell cycle research 2000;4():235-42.
249.
2000

M A Smith; A Nunomura; X Zhu; A Takeda; G Perry

Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease.
Antioxidants & redox signaling 2000;2(3):413-20.
250.
2000

H T Kim; R L Russell; A K Raina; P L Harris; S L Siedlak; X Zhu; R B Petersen; S Shimohama; M A Smith; G Perry

Protein disulfide isomerase in Alzheimer disease.
Antioxidants & redox signaling 2000;2(3):485-9.
251.
1999

G Perry; H Roder; A Nunomura; A Takeda; A L Friedlich; X Zhu; A K Raina; N Holbrook; S L Siedlak; P L Harris; et al.

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.
Neuroreport 1999;10(11):2411-5.
252.
1999

X Zhu; A K Raina; M A Smith

Cell cycle events in neurons. Proliferation or death?
The American journal of pathology 1999;155(2):327-9.

Zhu, Xiongwei
Case Western Reserve University

Zhu, Xiongwei

252 Publications

Zhu, Xiongwei Case Western Reserve University

Zhu, Xiongwei

252 Publications

Zhu, Xiongwei
Case Western Reserve University