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Younkin, Steven G

Grant Detail

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Mayo Alzheimer's Disease Research Center

1 May 1999 - 30 April 2014
NATIONAL INSTITUTE ON AGING
Total Funding: $ 23,843,907

FY 2011
5P50AG016574-13
$ 1,918,410
FY 2010
5P50AG016574-12
$ 1,952,866
FY 2009
2P50AG016574-11
$ 1,945,302
FY 2008
5P50AG016574-10
$ 1,823,414
FY 2007
5P50AG016574-09
$ 1,822,209
FY 2006
3P50AG016574-08S1
$ 49,999
FY 2006
5P50AG016574-08
$ 1,856,081
FY 2005
3P50AG016574-07S1
$ 66,413
FY 2005
3P50AG016574-07S2
$ 38,639
FY 2005
5P50AG016574-07
$ 1,819,299
FY 2004
2P50AG016574-06
$ 1,795,088
FY 2004
3P50AG016574-06S1
$ 134,939
FY 2004
3P50AG016574-06S2
$ 72,729
FY 2004
3P50AG016574-06S3
$ 2,000
FY 2003
3P50AG016574-05S1
$ 71,620
FY 2003
5P50AG016574-05
$ 1,734,074
FY 2002
3P50AG016574-04S1
$ 144,500
FY 2002
3P50AG016574-04S2
$ 52,378
FY 2002
5P50AG016574-04
$ 1,824,022
FY 2001
3P50AG016574-03S1
$ 123,176
FY 2001
3P50AG016574-03S2
$ 269,500
FY 2001
5P50AG016574-03
$ 1,411,001
FY 2000
3P50AG016574-02S2
$ 181,712
FY 2000
5P50AG016574-02
$ 1,316,900
FY 1999
3P50AG016574-01S4
$ 93,628
FY 1999
3P50AG016574-01S3
$ 90,000
FY 1999
3P50AG016574-01S2
$ 33,517
FY 1999
1P50AG016574-01
$ 1,200,491
 
 
$ 23,843,907
Abstract

The Mayo Alzheimer's Disease Research Center (ADRC) is located in Rochester, MN and Jacksonville, FL and will pursue two themes: 1) The recruitment and characterization of subjects in the early stages of the cognitive spectrum from aging to Alzheimer's disease (AD) particularly focusing on mild cognitive impairment (MCI), and 2) the study of non-AD dementias including frontotemporal lobar degeneration and dementia with Lewy bodies. The ADRC will consist of 5 cores: Administrative Core, Clinical Core, Data Management and Statistics Core, Neuropathology Core and Education and Information Transfer Core. The cores will interact with each other and will support three proposed research projects: 1) Identifying Multi-modality Imaging Correlates of Dementia with Lewy Bodies and AD, 2) The PGRN/TDP-43 Axis in Alzheimer's Disease and Neurodegeneration, and 3) Identification of AD Risk Variants by Genome Wide Association of Gene Expression. The cores will be led by established investigators in the field and the three projects will be directed by younger but experienced and productive investigators in their respective areas of research who have not been project leaders in the past. All three were trained in the ADRC environment by prominent investigators in dementia research and they will continue to explore well-established research themes. The ADRC staff has produced 340 publications, 70 chapters and 276 abstracts in the current grant cycle and will continue this productivity in the proposed grant cycle. The Center will continue its work on the UDS and contribute to the NACC database. Research on MCI, neuroimaging and clinical-pathological correlations will continue through the intense collaboration among the cores and projects. The ADRC will also continue to be a training platform for young investigators.

365 Resulting Publications

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