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Pericak-Vance, Margaret A.

Publication Detail

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Arnold-Chiari malformation with syringomyelia in an elderly woman.

C Geroldi; G B Frisoni; A Bianchetti; M Trabucchi; A Bricolo (Profiled Author: Frisoni, Giovanni B)

Alzheimer's Unit, IRCCS S. Giovanni di Dio, Sacro Cuore Fatebenefratelli Hospital, Brescia, Italy.
Age and ageing 1999;28(4):399-400.

Abstract

PRESENTATION: A 76-year-old woman, complaining of leg pain and unsteady gait for 3 years, presented with a spastic paraparetic gait, severe spasticity and touch, thermal and pain sensory loss limited to arms, lower thorax and upper abdomen. Brain and spinal cord magnetic resonance imaging showed a large loculated syrinx. Cerebellar tonsillar herniation into the foramen magnum was also seen (Arnold-Chiari malformation, type I). OUTCOME: The patient had successful cervico-spinal surgical decompression which resulted in marked reduction in hypertonia and weakness, normal gait and normal joint movement at 6 months. CONCLUSION: This unusual, late clinical presentation of a congenital disease underlines the importance of a comprehensive diagnostic work-up in the elderly patients with complex neurological signs.

Scientific Context

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