Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Apolipoprotein E and Alzheimer's disease.
W J Strittmatter (Profiled Author: Strittmatter, Warren J)
Division of Neurology, Duke University Medical Center 2900, Durham, North Carolina 27710, USA. warren@neuro.duke.edu
Annals of the New York Academy of Sciences 2000;924():91-2.
The specific molecular pathway by which apolipoprotein E modifies the expression of Alzheimer's disease remains elusive. Isoform-specific interactions of apolipoprotein E with other molecules determine the outcome from other neurologic disorders and may provide more tractable model systems.
Scientific Context
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Related Grants
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1.
COLE, GREGORY M
Preclinical Pharmacogenomics and Synaptic Biomarkers for Alzheimer's Disease
1 September 2011 - 31 March 2016
NATIONAL CENTER FOR COMPLEMENTARY &ALTERNATIVE MEDICINE
Total Funding: $ 766,150
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2.
Mayeux, Richard P
GENETIC EPIDEMIOLOGY OF ALZHEIMERS DISEASE IN HISPANICS
1 December 1998 - 31 January 2004
NATIONAL INSTITUTE ON AGING
Total Funding: $ 5,549,515
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3.
Smith, Mark A
METABOLIC ABNORMALITIES IN ALZHEIMER DISEASE
1 May 1999 - 30 April 2006
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Total Funding: $ 750,386
Related Publications
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1.
2006Gang Liu; Ping Men; Peggy L R Harris; Raj K Rolston; George Perry; Mark A Smith
Neuroscience letters 2006;406(3):189-93. -
2.
2006C Cordonnier; W M van der Flier; J D Sluimer; D Leys; F Barkhof; P Scheltens
Prevalence and severity of microbleeds in a memory clinic setting.
Neurology 2006;66(9):1356-60. -
3.
1997K S Montine; P J Kim; S J Olson; W R Markesbery; T J Montine
4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease.
Journal of neuropathology and experimental neurology 1997;56(8):866-71. -
4.
1996A D Roses
From genes to mechanisms to therapies: lessons to be learned from neurological disorders.
Nature medicine 1996;2(3):267-9.
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