Johns Hopkins University (JHU) - SciVal Experts v3.6

454 Publications

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications for this application is PubMed, so only PubMed publications are included.

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1.
2013

Carmen Gloria Ili; Priscilla Brebi; Oscar Tapia; Alejandra Sandoval; Jaime Lopez; Patricia Garcia; Pamela Leal; David Sidransky; Rafael Guerrero-Preston; Juan Carlos Roa

Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2013;32(3):316-22.
2.
2013

Mingzhao Xing; Ali S Alzahrani; Kathryn A Carson; David Viola; Rossella Elisei; Bela Bendlova; Linwah Yip; Caterina Mian; Federica Vianello; R Michael Tuttle; et al.

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.
JAMA : the journal of the American Medical Association 2013;309(14):1493-501.
3.
2013

Semra Demokan; Alice Y Chuang; Xiaofei Chang; Tanbir Khan; Ian M Smith; Kavita M Pattani; Santanu Dasgupta; Shahnaz Begum; Zubair Khan; Nanette J Liegeois; et al.

Identification of guanine nucleotide-binding protein γ-7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling.
International journal of oncology 2013;42(4):1427-36.
4.
2013

Mariana Brait; Enrico Munari; Cynthia Lebron; Maartje G Noordhuis; Shahnaz Begum; Christina Michailidi; Nilda Gonzalez-Roibon; Leonel Maldonado; Tanusree Sen; Rafael Guerrero-Preston; et al.

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma.
Cell cycle (Georgetown, Tex.) 2013;12(7):1058-70.
5.
2013

Santanu Dasgupta; Jin Sung Jang; Chunbo Shao; Nitai D Mukhopadhyay; Upneet K Sokhi; Swadesh K Das; Mariana Brait; Conover Talbot; Rex C Yung; Shahnaz Begum; et al.

SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling.
Journal of molecular medicine (Berlin, Germany) 2013;91(3):381-93.
6.
2013

Xiaoli Zhong; Sumit Isharwal; Jean M Naples; Clive Shiff; Robert W Veltri; Chunbo Shao; Kwabena M Bosompem; David Sidransky; Mohammad O Hoque

Hypermethylation of genes detected in urine from Ghanaian adults with bladder pathology associated with Schistosoma haematobium infection.
PloS one 2013;8(3):e59089.
7.
2012

Jong-Lyel Roh; William H Westra; Joseph A Califano; David Sidransky; Wayne M Koch

Tissue imprint for molecular mapping of deep surgical margins in patients with head and neck squamous cell carcinoma.
Head & neck 2012;34(11):1529-36.
8.
2012

Atul Bedi; Xiaofei Chang; Kimberly Noonan; Vui Pham; Rishi Bedi; Elana J Fertig; Michael Considine; Joseph A Califano; Ivan Borrello; Christine H Chung; et al.

Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy.
Molecular cancer therapeutics 2012;11(11):2429-39.
9.
2012

Hiroshi Katoh; Keishi Yamashita; Mina Waraya; Ofer Margalit; Akira Ooki; Hideaki Tamaki; Hiroyuki Sakagami; Kenichi Kokubo; David Sidransky; Masahiko Watanabe

Epigenetic silencing of HOPX promotes cancer progression in colorectal cancer.
Neoplasia (New York, N.Y.) 2012;14(7):559-71.
10.
2012

Mariana Brait; Myriam Loyo; Eli Rosenbaum; Kimberly L Ostrow; Alina Markova; Silvana Papagerakis; Marianna Zahurak; Steven M Goodman; Martha Zeiger; David Sidransky; et al.

Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer.
Epigenetics : official journal of the DNA Methylation Society 2012;7(7):710-9.
11.
2012

Santanu Dasgupta; Chunbo Shao; Thomas E Keane; David P Duberow; Richard A Mathies; Paul B Fisher; Lambertus A Kiemeney; David Sidransky

Detection of mitochondrial deoxyribonucleic acid alterations in urine from urothelial cell carcinoma patients.
International journal of cancer. Journal international du cancer 2012;131(1):158-64.
12.
2012

Eli Rosenbaum; Shahnaz Begum; Mariana Brait; Marianna Zahurak; Leonel Maldonado; Leslie A Mangold; Mario A Eisenberger; Jonathan I Epstein; Alan W Partin; David Sidransky; et al.

AIM1 promoter hypermethylation as a predictor of decreased risk of recurrence following radical prostatectomy.
The Prostate 2012;72(10):1133-9.
13.
2012

Santanu Dasgupta; Ethan Soudry; Nitai Mukhopadhyay; Chunbo Shao; John Yee; Stephan Lam; Wan Lam; Wei Zhang; Adi F Gazdar; Paul B Fisher; et al.

Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation.
Journal of cellular physiology 2012;227(6):2451-60.
14.
2012

Takenori Ogawa; Thomas E Liggett; Anatoliy A Melnikov; Constance L Monitto; Daniela Kusuke; Kiyoto Shiga; Toshimitsu Kobayashi; Akira Horii; Aditi Chatterjee; Victor V Levenson; et al.

Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance.
Cell cycle (Georgetown, Tex.) 2012;11(8):1656-63.
15.
2012

M Loyo; J Schussel; E Colantuoni; J Califano; M Brait; S Kang; W M Koch; D Sidransky; W H Westra; J M Taube

Detection of Merkel cell virus and correlation with histologic presence of Merkel cell carcinoma in sentinel lymph nodes.
British journal of cancer 2012;106(7):1314-9.
16.
2012

M Pia Morelli; Emiliano Calvo; Esther Ordoñez; Michael J Wick; Belen-Rubio Viqueira; Pedro P Lopez-Casas; Elizabeth Bruckheimer; Antonio Calles-Blanco; David Sidransky; Manuel Hidalgo

Prioritizing phase I treatment options through preclinical testing on personalized tumorgraft.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(4):e45-8.
17.
2012

Priscilla Brebi-Mieville; Carmen Ili-Gangas; Pamela Leal-Rojas; Maartje G Noordhuis; Ethan Soudry; Jimena Perez; Juan Carlos Roa; David Sidransky; Rafael Guerrero-Preston

Clinical and public health research using methylated DNA immunoprecipitation (MeDIP): a comparison of commercially available kits to examine differential DNA methylation across the genome.
Epigenetics : official journal of the DNA Methylation Society 2012;7(1):106-12.
18.
2012

Daria Gaykalova; Rajita Vatapalli; Chad A Glazer; Sheetal Bhan; Chunbo Shao; David Sidransky; Patrick K Ha; Joseph A Califano

Dose-dependent activation of putative oncogene SBSN by BORIS.
PloS one 2012;7(7):e40389.
19.
2012

Mariana Brait; Shizhang Ling; Jatin K Nagpal; Xiaofei Chang; Hannah Lui Park; Juna Lee; Jun Okamura; Keishi Yamashita; David Sidransky; Myoung Sook Kim

Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers.
PloS one 2012;7(9):e44951.
20.
2012

Chunbo Shao; Marietta Tan; Justin A Bishop; Jia Liu; Weiliang Bai; Daria A Gaykalova; Takenori Ogawa; Ami R Vikani; Yuri Agrawal; Ryan J Li; et al.

Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma.
PloS one 2012;7(11):e48582.
21.
2012

Tanusree Sen; Nilkantha Sen; Maartje G Noordhuis; Rajani Ravi; T-C Wu; Patrick K Ha; David Sidransky; Mohammad Obaidul Hoque

OGDHL is a modifier of AKT-dependent signaling and NF-κB function.
PloS one 2012;7(11):e48770.
22.
2011

Tanusree Sen; Nilkantha Sen; Yiping Huang; Debasish Sinha; Zhen-Ge Luo; Edward A Ratovitski; David Sidransky

Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.
The Journal of biological chemistry 2011;286(50):43204-13.
23.
2011

Mei Zhao; Daisuke Sano; Curtis R Pickering; Samar A Jasser; Ying C Henderson; Gary L Clayman; Erich M Sturgis; Thomas J Ow; Reuben Lotan; Thomas E Carey; et al.

Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(23):7248-64.
24.
2011

Nishant Agrawal; Mitchell J Frederick; Curtis R Pickering; Chetan Bettegowda; Kyle Chang; Ryan J Li; Carole Fakhry; Tong-Xin Xie; Jiexin Zhang; Jing Wang; et al.

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.
Science (New York, N.Y.) 2011;333(6046):1154-7.
25.
2011

Manuel Hidalgo; Elizabeth Bruckheimer; N V Rajeshkumar; Ignacio Garrido-Laguna; Elizabeth De Oliveira; Belen Rubio-Viqueira; Steven Strawn; Michael J Wick; James Martell; David Sidransky

A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer.
Molecular cancer therapeutics 2011;10(8):1311-6.
26.
2011

Yong Gu Cho; Xiaofei Chang; Il-Seok Park; Keishi Yamashita; Chunbo Shao; Patrick K Ha; Sara I Pai; David Sidransky; Myoung Sook Kim

Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma.
International journal of oncology 2011;39(2):337-44.
27.
2011

André Lopes Carvalho; Rui Henrique; Carmen Jeronimo; Chetan S Nayak; Ashok N Reddy; Mohammad O Hoque; Steven Chang; Mariana Brait; Wei-Wen Jiang; Michael M Kim; et al.

Detection of promoter hypermethylation in salivary rinses as a biomarker for head and neck squamous cell carcinoma surveillance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(14):4782-9.
28.
2011

Chunbo Shao; Wenyue Sun; Marietta Tan; Chad A Glazer; Sheetal Bhan; Xiaoli Zhong; Carole Fakhry; Rajni Sharma; William H Westra; Mohammad O Hoque; et al.

Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(13):4320-30.
29.
2011

Sheetal Bhan; Sandeep S Negi; Chunbo Shao; Chad A Glazer; Alice Chuang; Daria A Gaykalova; Wenyue Sun; David Sidransky; Patrick K Ha; Joseph A Califano

BORIS binding to the promoters of cancer testis antigens, MAGEA2, MAGEA3, and MAGEA4, is associated with their transcriptional activation in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(13):4267-76.
30.
2011

R Guerrero-Preston; E Soudry; J Acero; M Orera; L Moreno-López; G Macía-Colón; A Jaffe; M Berdasco; C Ili-Gangas; P Brebi-Mieville; et al.

NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.
Cancer prevention research (Philadelphia, Pa.) 2011;4(7):1061-72.
31.
2011

Y Huang; A Chuang; H Hao; C Talbot; T Sen; B Trink; D Sidransky; E Ratovitski

Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells.
Cell death and differentiation 2011;18(7):1220-30.
32.
2011

Shahnaz Begum; Mariana Brait; Santanu Dasgupta; Kimberly L Ostrow; Marianna Zahurak; André L Carvalho; Joseph A Califano; Steven N Goodman; William H Westra; Mohammad Obaidul Hoque; et al.

An epigenetic marker panel for detection of lung cancer using cell-free serum DNA.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(13):4494-503.
33.
2011

Shizhang Ling; Xiaofei Chang; Luciana Schultz; Thomas K Lee; Alcides Chaux; Luigi Marchionni; George J Netto; David Sidransky; David M Berman

An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer.
Cancer research 2011;71(11):3812-21.
34.
2011

Yiping Huang; Xiaofei Chang; Juna Lee; Yong Gu Cho; Xiaoli Zhong; Il-Seok Park; Jun-Wei Liu; Joseph A Califano; Edward A Ratovitski; David Sidransky; et al.

Cigarette smoke induces promoter methylation of single-stranded DNA-binding protein 2 in human esophageal squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2011;128(10):2261-73.
35.
2011

Aditi Chatterjee; Santanu Dasgupta; David Sidransky

Mitochondrial subversion in cancer.
Cancer prevention research (Philadelphia, Pa.) 2011;4(5):638-54.
36.
2011

Mariana Brait; David Sidransky

Cancer epigenetics: above and beyond.
Toxicology mechanisms and methods 2011;21(4):275-88.
37.
2011

Chunbo Shao; Weiliang Bai; Jacqueline C Junn; Mamoru Uemura; Patrick T Hennessey; David Zaboli; David Sidransky; Joseph A Califano; Patrick K Ha

Evaluation of MYB promoter methylation in salivary adenoid cystic carcinoma.
Oral oncology 2011;47(4):251-5.
38.
2011

Xiaofei Chang; Keishi Yamashita; David Sidransky; Myoung Sook Kim

Promoter methylation of heat shock protein B2 in human esophageal squamous cell carcinoma.
International journal of oncology 2011;38(4):1129-35.
39.
2011

Myriam Loyo; Mariana Brait; Myoung S Kim; Kimberly L Ostrow; Chunfa C Jie; Alice Y Chuang; Joseph A Califano; Nanette J Liégeois; Shahnaz Begum; William H Westra; et al.

A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma.
International journal of cancer. Journal international du cancer 2011;128(6):1393-403.
40.
2011

I Kogan-Sakin; Y Tabach; Y Buganim; A Molchadsky; H Solomon; S Madar; I Kamer; P Stambolsky; A Shelly; N Goldfinger; et al.

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.
Cell death and differentiation 2011;18(2):271-81.
41.
2011

Tanusree Sen; Nilkantha Sen; Mariana Brait; Shahnaz Begum; Aditi Chatterjee; Mohammad Obaidul Hoque; Edward Ratovitski; David Sidransky

DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation.
Cancer research 2011;71(3):1167-76.
42.
2011

Mark McClellan; Joshua Benner; Richard Schilsky; David Epstein; Ray Woosley; Stephen Friend; David Sidransky; Cindy Geoghegan; David Kessler

An accelerated pathway for targeted cancer therapies.
Nature reviews. Drug discovery 2011;10(2):79-80.
43.
2011

Il-Seok Park; Xiaofei Chang; Myriam Loyo; Gaosong Wu; Alice Chuang; Myoung Sook Kim; Young Kwang Chae; Sofia Lyford-Pike; William H Westra; John R Saunders; et al.

Characterization of the methylation patterns in human papillomavirus type 16 viral DNA in head and neck cancers.
Cancer prevention research (Philadelphia, Pa.) 2011;4(2):207-17.
44.
2011

Jong-Lyel Roh; Sung Koo Kang; Il Minn; Joseph A Califano; David Sidransky; Wayne M Koch

p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma.
Oral oncology 2011;47(1):8-15.
45.
2011

Xiaofei Chang; Rajani Ravi; Vui Pham; Atul Bedi; Aditi Chatterjee; David Sidransky

Adenylate kinase 3 sensitizes cells to cigarette smoke condensate vapor induced cisplatin resistance.
PloS one 2011;6(6):e20806.
46.
2010

Tanusree Sen; Xiaofei Chang; David Sidransky; Aditi Chatterjee

Regulation of ΔNp63α by NFκΒ.
Cell cycle (Georgetown, Tex.) 2010;9(24):4841-7.
47.
2010

Mohammad Obaidul Hoque; Mariana Brait; Eli Rosenbaum; Maria Luana Poeta; Prodipto Pal; Shahnaz Begum; Santanu Dasgupta; Andre L Carvalho; Steven A Ahrendt; William H Westra; et al.

Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(12):1887-93.
48.
2010

Luciana Schultz; Roula Albadine; Jessica Hicks; Sana Jadallah; Angelo M DeMarzo; Ying-Bei Chen; Matthew E Nielsen; Matthew E Neilsen; Mark L Gonzalgo; David Sidransky; et al.

Expression status and prognostic significance of mammalian target of rapamycin pathway members in urothelial carcinoma of urinary bladder after cystectomy.
Cancer 2010;116(23):5517-26.
49.
2010

Semra Demokan; Xiaofei Chang; Alice Chuang; Wojciech K Mydlarz; Jatinder Kaur; Peng Huang; Zubair Khan; Tanbir Khan; Kimberly L Ostrow; Mariana Brait; et al.

KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses.
International journal of cancer. Journal international du cancer 2010;127(10):2351-9.
50.
2010

Kavita Malhotra Pattani; Zhe Zhang; Semra Demokan; Chad Glazer; Myriam Loyo; Steven Goodman; David Sidransky; Francisco Bermudez; Germain Jean-Charles; Thomas McCaffrey; et al.

Endothelin receptor type B gene promoter hypermethylation in salivary rinses is independently associated with risk of oral cavity cancer and premalignancy.
Cancer prevention research (Philadelphia, Pa.) 2010;3(9):1093-103.
51.
2010

Santanu Dasgupta; Rachel Koch; William H Westra; Joseph A Califano; Patrick K Ha; David Sidransky; Wayne M Koch

Mitochondrial DNA mutation in normal margins and tumors of recurrent head and neck squamous cell carcinoma patients.
Cancer prevention research (Philadelphia, Pa.) 2010;3(9):1205-11.
52.
2010

Rafael Guerrero-Preston; Lynn R Goldman; Priscilla Brebi-Mieville; Carmen Ili-Gangas; Cynthia Lebron; Frank R Witter; Ben J Apelberg; Marina Hernández-Roystacher; Andrew Jaffe; Rolf U Halden; et al.

Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds.
Epigenetics : official journal of the DNA Methylation Society 2010;5(6):539-46.
53.
2010

Juna Lee; Se Jin Jang; Nicole Benoit; Mohammad O Hoque; Joseph A Califano; Barry Trink; David Sidransky; Li Mao; Chulso Moon

Presence of 5-methylcytosine in CpNpG trinucleotides in the human genome.
Genomics 2010;96(2):67-72.
54.
2010

Eleftherios P Diamandis; David Sidransky; Peter W Laird; Paul Cairns; Bharati Bapat

Epigenomics-based diagnostics.
Clinical chemistry 2010;56(8):1216-9.
55.
2010

Myoung Sook Kim; Yiping Huang; Juna Lee; Xiaoli Zhong; Wei-Wen Jiang; Edward A Ratovitski; David Sidransky

Cellular transformation by cigarette smoke extract involves alteration of glycolysis and mitochondrial function in esophageal epithelial cells.
International journal of cancer. Journal international du cancer 2010;127(2):269-81.
56.
2010

Kimberly Laskie Ostrow; Mohammad O Hoque; Myriam Loyo; Marianna Brait; Alissa Greenberg; Jill M Siegfried; Jennifer R Grandis; Autumn Gaither Davis; William L Bigbee; William Rom; et al.

Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation-specific PCR.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(13):3463-72.
57.
2010

Myriam Loyo; Rafael Guerrero-Preston; Mariana Brait; Mohmammad O Hoque; Alice Chuang; Myoung S Kim; Rajni Sharma; Nanette J Liégeois; Wayne M Koch; Joseph A Califano; et al.

Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission.
International journal of cancer. Journal international du cancer 2010;126(12):2991-6.
58.
2010

A Ooki; K Yamashita; S Kikuchi; S Sakuramoto; N Katada; K Kokubo; H Kobayashi; M S Kim; D Sidransky; M Watanabe

Potential utility of HOP homeobox gene promoter methylation as a marker of tumor aggressiveness in gastric cancer.
Oncogene 2010;29(22):3263-75.
59.
2010

Howard Donninger; Luke Hesson; Michele Vos; Kristin Beebe; Laura Gordon; David Sidransky; Jun Wei Liu; Thomas Schlegel; Shannon Payne; Arndt Hartmann; et al.

The Ras effector RASSF2 controls the PAR-4 tumor suppressor.
Molecular and cellular biology 2010;30(11):2608-20.
60.
2010

Xiaofei Chang; Constance L Monitto; Semra Demokan; Myoung Sook Kim; Steven S Chang; Xiaoli Zhong; Joseph A Califano; David Sidransky

Identification of hypermethylated genes associated with cisplatin resistance in human cancers.
Cancer research 2010;70(7):2870-9.
61.
2010

Yosef Buganim; Hilla Solomon; Yoach Rais; Daria Kistner; Ido Nachmany; Mariana Brait; Shalom Madar; Ido Goldstein; Eyal Kalo; Nitzan Adam; et al.

p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways.
Cancer research 2010;70(6):2274-84.
62.
2010

Myoung Sook Kim; Juna Lee; David Sidransky

DNA methylation markers in colorectal cancer.
Cancer metastasis reviews 2010;29(1):181-206.
63.
2010

Aditi Chatterjee; Xiaofei Chang; Tanusree Sen; Rajani Ravi; Atul Bedi; David Sidransky

Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta.
Cancer research 2010;70(4):1419-29.
64.
2010

Yiping Huang; Alice Y Chuang; Rose-Anne Romano; Nanette J Liégeois; Satrajit Sinha; Barry Trink; Edward Ratovitski; David Sidransky

Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure.
Cell cycle (Georgetown, Tex.) 2010;9(2):328-38.
65.
2010

Aditi Chatterjee; Tanusree Sen; Xiaofei Chang; David Sidransky

Yes-associated protein 1 regulates the stability of DeltaNp63alpha.
Cell cycle (Georgetown, Tex.) 2010;9(1):162-7.
66.
2010

Myoung Sook Kim; Xiaofei Chang; Cynthia LeBron; Jatin K Nagpal; Juna Lee; Yiping Huang; Keishi Yamashita; Barry Trink; Edward A Ratovitski; David Sidransky

Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma.
PloS one 2010;5(2):e9003.
67.
2010

Megan L Durr; Wojciech K Mydlarz; Chunbo Shao; Marianna L Zahurak; Alice Y Chuang; Mohammad O Hoque; William H Westra; Nanette J Liegeois; Joseph A Califano; David Sidransky; et al.

Quantitative methylation profiles for multiple tumor suppressor gene promoters in salivary gland tumors.
PloS one 2010;5(5):e10828.
68.
2009

Santanu Dasgupta; Mohammad Obaidul Hoque; Sunil Upadhyay; David Sidransky

Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV-HUC-1 cells.
International journal of cancer. Journal international du cancer 2009;125(12):2829-35.
69.
2009

Mariana Brait; Jean G Ford; Srinivas Papaiahgari; Mary A Garza; Jin I Lee; Myriam Loyo; Leonel Maldonado; Shahnaz Begum; Lee McCaffrey; Mollie Howerton; et al.

Association between lifestyle factors and CpG island methylation in a cancer-free population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):2984-91.
70.
2009

Mohammad Obaidul Hoque; Maria Prencipe; Maria Luana Poeta; Raffaela Barbano; Vanna Maria Valori; Massimiliano Copetti; Antonietta Pia Gallo; Mariana Brait; Evaristo Maiello; Adolfo Apicella; et al.

Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(10):2694-700.
71.
2009

Joram Slager; Betty Tyler; Ariella Shikanov; Abraham J Domb; Kuslima Shogen; David Sidransky; Henry Brem

Local controlled delivery of anti-neoplastic RNAse to the brain.
Pharmaceutical research 2009;26(8):1838-46.
72.
2009

Patrick K Ha; Steven S Chang; Chad A Glazer; Joseph A Califano; David Sidransky

Molecular techniques and genetic alterations in head and neck cancer.
Oral oncology 2009;45(4-5):335-9.
73.
2009

Kimberly Laskie Ostrow; Hannah Lui Park; Mohammad Obaidul Hoque; Myoung Sook Kim; Junwei Liu; Pedram Argani; William Westra; Wim Van Criekinge; David Sidransky

Pharmacologic unmasking of epigenetically silenced genes in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1184-91.
74.
2009

Santanu Dasgupta; Rex C Yung; William H Westra; David A Rini; Johann Brandes; David Sidransky

Following mitochondrial footprints through a long mucosal path to lung cancer.
PloS one 2009;4(8):e6533.
75.
2009

Myoung Sook Kim; Joost Louwagie; Beatriz Carvalho; Jochim S Terhaar Sive Droste; Hannah Lui Park; Young Kwang Chae; Keishi Yamashita; Junwei Liu; Kimberly Laskie Ostrow; Shizhang Ling; et al.

Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer.
PloS one 2009;4(8):e6555.
76.
2008

Steven S Chang; Wei Wen Jiang; Ian Smith; Luana M Poeta; Shahnaz Begum; Chad Glazer; Shannon Shan; William Westra; David Sidransky; Joseph A Califano

MicroRNA alterations in head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2008;123(12):2791-7.
77.
2008

Boris Gorelik; Irit Ziv; Revital Shohat; Michael Wick; W David Hankins; David Sidransky; Zvia Agur

Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: a new theranostic method combining xenografted biopsies with a mathematical model.
Cancer research 2008;68(21):9033-40.
78.
2008

Mariana Brait; Shahnaz Begum; André L Carvalho; Santanu Dasgupta; André L Vettore; Bogdan Czerniak; Otávia L Caballero; William H Westra; David Sidransky; Mohammad Obaidul Hoque

Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(10):2786-94.
79.
2008

Yiping Huang; Tanusree Sen; Jatin Nagpal; Sunil Upadhyay; Barry Trink; Edward Ratovitski; David Sidransky

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage.
Cell cycle (Georgetown, Tex.) 2008;7(18):2846-55.
80.
2008

Yutaka Tokumaru; Keishi Yamashita; Myoung Sook Kim; Hannah L Park; Motonobu Osada; Masaki Mori; David Sidransky

The role of PGP9.5 as a tumor suppressor gene in human cancer.
International journal of cancer. Journal international du cancer 2008;123(4):753-9.
81.
2008

Jatin K Nagpal; Santanu Dasgupta; Sana Jadallah; Young K Chae; Edward A Ratovitski; Antoun Toubaji; George J Netto; Toby Eagle; Aviram Nissan; David Sidransky; et al.

Profiling the expression pattern of GPI transamidase complex subunits in human cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(8):979-91.
82.
2008

Sung Koo Kang; Young Kwang Chae; Janghee Woo; Myoung Sook Kim; Jong Chul Park; Juna Lee; Jean Charles Soria; Se Jin Jang; David Sidransky; Chulso Moon

Role of human aquaporin 5 in colorectal carcinogenesis.
The American journal of pathology 2008;173(2):518-25.
83.
2008

Jun-Wei Liu; Jatin K Nagpal; Wenyue Sun; Juna Lee; Myoung Sook Kim; Kimberly L Ostrow; Shaoyu Zhou; Carmen Jeronimo; Rui Henrique; Wim Van Criekinge; et al.

ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3754-60.
84.
2008

A Chatterjee; X Chang; J K Nagpal; S Chang; S Upadhyay; J Califano; B Trink; D Sidransky

Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis.
Oncogene 2008;27(26):3710-20.
85.
2008

Janghee Woo; Juna Lee; Young Kwang Chae; Myoung Sook Kim; Jin Hyen Baek; Jong Chul Park; Min Joo Park; Ian M Smith; Barry Trink; Edward Ratovitski; et al.

Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation.
Cancer letters 2008;264(1):54-62.
86.
2008

M S Kim; X Chang; K Yamashita; J K Nagpal; J H Baek; G Wu; B Trink; E A Ratovitski; M Mori; D Sidransky

Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma.
Oncogene 2008;27(25):3624-34.
87.
2008

Yiping Huang; Mohammad Obaidul Hoque; Feng Wu; Barry Trink; David Sidransky; Edward A Ratovitski

Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes.
Cell cycle (Georgetown, Tex.) 2008;7(11):1613-22.
88.
2008

Hannah Lui Park; Myoung Sook Kim; Keishi Yamashita; William Westra; Andre Lopes Carvalho; Juna Lee; Wei-Wen Jiang; Jin Hyen Baek; Junwei Liu; Motonobu Osada; et al.

DCC promoter hypermethylation in esophageal squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2008;122(11):2498-502.
89.
2008

David Sidransky

The oral cavity as a molecular mirror of lung carcinogenesis.
Cancer prevention research (Philadelphia, Pa.) 2008;1(1):12-4.
90.
2008

Myoung Sook Kim; Cinthia Lebron; Jatin K Nagpal; Young Kwang Chae; Xiaofei Chang; Yiping Huang; Tony Chuang; Keishi Yamashita; Barry Trink; Edward A Ratovitski; et al.

Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer.
Biochemical and biophysical research communications 2008;370(1):38-43.
91.
2008

Aditi Chatterjee; Sunil Upadhyay; Xiaofei Chang; Jatin K Nagpal; Barry Trink; David Sidransky

U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.
Cell cycle (Georgetown, Tex.) 2008;7(9):1231-7.
92.
2008

Carmen Jeronimo; Paula Monteiro; Rui Henrique; Mário Dinis-Ribeiro; Isabel Costa; Vera L Costa; Luísa Filipe; André L Carvalho; Mohammad O Hoque; Irene Pais; et al.

Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions.
Breast cancer research and treatment 2008;109(1):27-34.
93.
2008

Mohammad Obaidul Hoque; Myoung Sook Kim; Kimberly Laskie Ostrow; Junwei Liu; G Bea A Wisman; Hannah Lui Park; Maria Luana Poeta; Carmen Jeronimo; Rui Henrique; Agnes Lendvai; et al.

Genome-wide promoter analysis uncovers portions of the cancer methylome.
Cancer research 2008;68(8):2661-70.
94.
2008

M S Kim; X Chang; J K Nagpal; K Yamashita; J H Baek; S Dasgupta; G Wu; M Osada; J-H Woo; W H Westra; et al.

The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
Oncogene 2008;27(14):2045-54.
95.
2008

Janghee Woo; Juna Lee; Myoung Sook Kim; Se Jin Jang; David Sidransky; Chulso Moon

The effect of aquaporin 5 overexpression on the Ras signaling pathway.
Biochemical and biophysical research communications 2008;367(2):291-8.
96.
2008

Jun-Wei Liu; Jatin K Nagpal; Carmen Jeronimo; Ji Eun Lee; Rui Henrique; Myoung Sook Kim; Kimberly L Ostrow; Keishi Yamashita; Vim van Criekinge; Guojun Wu; et al.

Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer.
The Prostate 2008;68(4):418-26.
97.
2008

Janghee Woo; Young Kwang Chae; Se Jin Jang; Myoung Sook Kim; Jin Hyen Baek; Jong Chul Park; Barry Trink; Edward Ratovitski; Taekyul Lee; Beomsoo Park; et al.

Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium.
Biochemical and biophysical research communications 2008;366(2):321-7.
98.
2008

Mohammad Obaidul Hoque; Shahnaz Begum; Mariana Brait; Carmen Jeronimo; Marianna Zahurak; Kimberly Laskie Ostrow; Eli Rosenbaum; Bruce Trock; William H Westra; Mark Schoenberg; et al.

Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.
The Journal of urology 2008;179(2):743-7.
99.
2008

Santanu Dasgupta; Mohammad Obaidul Hoque; Sunil Upadhyay; David Sidransky

Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer.
Cancer research 2008;68(3):700-6.
100.
2008

William H Westra; Janis M Taube; M L Poeta; Shanaz Begum; David Sidransky; Wayne M Koch

Inverse relationship between human papillomavirus-16 infection and disruptive p53 gene mutations in squamous cell carcinoma of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):366-9.
101.
2008

Jong Chul Park; Young Kwang Chae; Choon Hee Son; Myoung Sook Kim; Juna Lee; Kimberly Ostrow; David Sidransky; Mohammad Obaidul Hoque; Chulso Moon

Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer.
Biochemical and biophysical research communications 2008;365(2):221-6.
102.
2008

Chul-So Moon; Eddy C Agbo; David Sidransky

Slow development impedes the uptake of diagnostics.
Nature 2008;451(7174):16.
103.
2008

Samantha Maragh; John P Jakupciak; Paul D Wagner; William N Rom; David Sidransky; Sudhir Srivastava; Catherine D O'Connell

Multiple strand displacement amplification of mitochondrial DNA from clinical samples.
BMC medical genetics 2008;9():7.
104.
2008

Keishi Yamashita; Myoung Sook Kim; Hannah Lui Park; Yutaka Tokumaru; Motonobu Osada; Hiroshi Inoue; Masaki Mori; David Sidransky

HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma.
Molecular cancer research : MCR 2008;6(1):31-41.
105.
2008

André Lopes Carvalho; Carmen Jeronimo; Michael M Kim; Rui Henrique; Zhe Zhang; Mohammad O Hoque; Steve Chang; Mariana Brait; Chetan S Nayak; Wei-Wen Jiang; et al.

Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):97-107.
106.
2008

Young Kwang Chae; Janghee Woo; Mi-Jung Kim; Sung Koo Kang; Myoung Sook Kim; Juna Lee; Seung Koo Lee; Gyungyub Gong; Yong Hee Kim; Jean Charles Soria; et al.

Expression of aquaporin 5 (AQP5) promotes tumor invasion in human non small cell lung cancer.
PloS one 2008;3(5):e2162.
107.
2008

Young Kwang Chae; Sung Koo Kang; Myoung Sook Kim; Janghee Woo; Juna Lee; Steven Chang; Dong-Wook Kim; Myungshin Kim; Seonyang Park; Inho Kim; et al.

Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML).
PloS one 2008;3(7):e2594.
108.
2008

Yan Cui; Ying Ying; Andrew van Hasselt; Ka Man Ng; Jun Yu; Qian Zhang; Jie Jin; Dingxie Liu; Johng S Rhim; Sun Young Rha; et al.

OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation.
PloS one 2008;3(8):e2990.
109.
2008

John P Jakupciak; Samantha Maragh; Maura E Markowitz; Alissa K Greenberg; Mohammad O Hoque; Anirban Maitra; Peter E Barker; Paul D Wagner; William N Rom; Sudhir Srivastava; et al.

Performance of mitochondrial DNA mutations detecting early stage cancer.
BMC cancer 2008;8():285.
110.
2007

M Luana Poeta; Judith Manola; Meredith A Goldwasser; Arlene Forastiere; Nicole Benoit; Joseph A Califano; John A Ridge; Jarrard Goodwin; Daniel Kenady; John Saunders; et al.

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.
The New England journal of medicine 2007;357(25):2552-61.
111.
2007

Marion E Couch; Robert L Ferris; Joseph A Brennan; Wayne M Koch; Elizabeth M Jaffee; Michael S Leibowitz; Gerald T Nepom; Henry A Erlich; David Sidransky

Alteration of cellular and humoral immunity by mutant p53 protein and processed mutant peptide in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7199-206.
112.
2007

Douglas W Ball; Ning Jin; D Marc Rosen; Alan Dackiw; David Sidransky; Mingzhao Xing; Barry D Nelkin

Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
The Journal of clinical endocrinology and metabolism 2007;92(12):4712-8.
113.
2007

Myoung Sook Kim; Keishi Yamashita; Young Kwang Chae; Yutaka Tokumaru; Xiaofei Chang; Marianna Zahurak; Motonobu Osada; Hannah Lui Park; Alice Chuang; Joseph A Califano; et al.

A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(22 Pt 1):6658-65.
114.
2007

Jun-Wei Liu; Myoung Sook Kim; Jatin Nagpal; Keishi Yamashita; Luana Poeta; Xiaofei Chang; Juna Lee; Hannah Lui Park; Carmen Jeronimo; William H Westra; et al.

Quantitative hypermethylation of NMDAR2B in human gastric cancer.
International journal of cancer. Journal international du cancer 2007;121(9):1994-2000.
115.
2007

Rui Henrique; Franclim R Ribeiro; Daniel Fonseca; Mohammad O Hoque; André L Carvalho; Vera L Costa; Mafalda Pinto; Jorge Oliveira; Manuel R Teixeira; David Sidransky; et al.

High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6122-9.
116.
2007

Chetan S Nayak; André Lopes Carvalho; Carmen Jeronimo; Rui Henrique; Michael M Kim; Mohammad O Hoque; Steve Chang; Wei-Wen Jiang; Wayne Koch; William Westra; et al.

Positive correlation of tissue inhibitor of metalloproteinase-3 and death-associated protein kinase hypermethylation in head and neck squamous cell carcinoma.
The Laryngoscope 2007;117(8):1376-80.
117.
2007

Sokbom Kang; Hy-Sook Kim; Sang Soo Seo; Sang-Yoon Park; David Sidransky; Seung Myung Dong

Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma.
Gynecologic oncology 2007;105(3):662-6.
118.
2007

Sunil Upadhyay; Aditi Chatterjee; Barry Trink; Matthias Sommer; Edward Ratovitski; David Sidransky

TAp63gamma regulates hOGG1 and repair of oxidative damage in cancer cell lines.
Biochemical and biophysical research communications 2007;356(4):823-8.
119.
2007

Guojun Wu; Zhongmin Guo; Xiaofei Chang; Myoung Sook Kim; Jatin K Nagpal; Junwei Liu; Joni M Maki; Kari I Kivirikko; Stephen P Ethier; Barry Trink; et al.

LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Cancer research 2007;67(9):4123-9.
120.
2007

Shaoyu Zhou; Sushant Kachhap; Wenyue Sun; Guojun Wu; Alice Chuang; Luana Poeta; Lawson Grumbine; Suhail K Mithani; Aditi Chatterjee; Wayne Koch; et al.

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7540-5.
121.
2007

Motonobu Osada; Hannah Lui Park; Min Joo Park; Jun-Wei Liu; Guojun Wu; Barry Trink; David Sidransky

A p53-type response element in the GDF15 promoter confers high specificity for p53 activation.
Biochemical and biophysical research communications 2007;354(4):913-8.
122.
2007

Chunyan Liu; Shaoyu Zhou; Shahnaz Begum; David Sidransky; William H Westra; Malcolm Brock; Joseph A Califano

Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2007;55(3):303-11.
123.
2007

T J Seng; J S W Low; H Li; Y Cui; H K Goh; M L Y Wong; G Srivastava; D Sidransky; J Califano; R D M Steenbergen; et al.

The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation.
Oncogene 2007;26(6):934-44.
124.
2007

Barry Trink; Motonobu Osada; Edward Ratovitski; David Sidransky

p63 transcriptional regulation of epithelial integrity and cancer.
Cell cycle (Georgetown, Tex.) 2007;6(3):240-5.
125.
2007

Wei-Wen Jiang; Marianna Zahurak; Zeng-Tong Zhou; Hannah Lui Park; Zhong-Min Guo; Guo-Jun Wu; David Sidransky; Barry Trink; Joseph A Califano

Alterations of GPI transamidase subunits in head and neck squamous carcinoma.
Molecular cancer 2007;6():74.
126.
2006

T K Mehta; M O Hoque; R Ugarte; M H Rahman; E Kraus; R Montgomery; K Melancon; D Sidransky; H Rabb

Quantitative detection of promoter hypermethylation as a biomarker of acute kidney injury during transplantation.
Transplantation proceedings 2006;38(10):3420-6.
127.
2006

Wei-Wen Jiang; Marianna Zahurak; David Goldenberg; Yelena Milman; Hannah Lui Park; William H Westra; Wayne Koch; David Sidransky; Joseph Califano

Increased plasma DNA integrity index in head and neck cancer patients.
International journal of cancer. Journal international du cancer 2006;119(11):2673-6.
128.
2006

William H Westra; David Sidransky

Fluorescence visualization in oral neoplasia: shedding light on an old problem.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6594-7.
129.
2006

Rui Henrique; Vera Lúcia Costa; Nuno Cerveira; André Lopes Carvalho; Mohammad Obaidul Hoque; Franclim Ricardo Ribeiro; Jorge Oliveira; Manuel Rodrigues Teixeira; David Sidransky; Carmen Jerónimo

Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
Journal of molecular medicine (Berlin, Germany) 2006;84(11):911-8.
130.
2006

Guojun Wu; Zhongmin Guo; Aditi Chatterjee; Xin Huang; Ethel Rubin; Feng Wu; Elizabeth Mambo; Xiaofei Chang; Motonobu Osada; Myoung Sook Kim; et al.

Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer.
Cancer research 2006;66(20):9829-36.
131.
2006

G Bea A Wisman; Esther R Nijhuis; Mohammad O Hoque; Nathalie Reesink-Peters; Alice J Koning; Haukeline H Volders; Henk J Buikema; H Marike Boezen; Harry Hollema; Ed Schuuring; et al.

Assessment of gene promoter hypermethylation for detection of cervical neoplasia.
International journal of cancer. Journal international du cancer 2006;119(8):1908-14.
132.
2006

André Lopes Carvalho; Alice Chuang; Wei-Wen Jiang; Juna Lee; Shahnaz Begum; Luana Poeta; Ming Zhao; Carmen Jerónimo; Rui Henrique; Chetan S Nayak; et al.

Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma.
Cancer research 2006;66(19):9401-7.
133.
2006

Anju Singh; Vikas Misra; Rajesh K Thimmulappa; Hannah Lee; Stephen Ames; Mohammad O Hoque; James G Herman; Stephen B Baylin; David Sidransky; Edward Gabrielson; et al.

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
PLoS medicine 2006;3(10):e420.
134.
2006

Sokbom Kang; Jae Myun Lee; Eun-Sook Jeon; Sun Lee; Hogeun Kim; Hy-Sook Kim; Sang-Soo Seo; Sang-Yoon Park; David Sidransky; Seung Myung Dong

RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma.
International journal of cancer. Journal international du cancer 2006;119(6):1316-21.
135.
2006

Mohammad O Hoque; Qinghua Feng; Papa Toure; Amadou Dem; Cathy W Critchlow; Stephen E Hawes; Troy Wood; Carmen Jeronimo; Eli Rosenbaum; Joshua Stern; et al.

Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(26):4262-9.
136.
2006

Shaoyu Zhou; Keyaunoosh Kassauei; David J Cutler; Giulia C Kennedy; David Sidransky; Anirban Maitra; Joseph Califano

An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome.
The Journal of molecular diagnostics : JMD 2006;8(4):476-82.
137.
2006

Matthias Sommer; Nina Poliak; Sunil Upadhyay; Edward Ratovitski; Barry D Nelkin; Lawrence A Donehower; David Sidransky

DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse.
Cell cycle (Georgetown, Tex.) 2006;5(17):2005-11.
138.
2006

Sunil Upadhyay; Chunyan Liu; Aditi Chatterjee; Mohammad O Hoque; Myoung Sook Kim; James Engles; William Westra; Barry Trink; Edward Ratovitski; David Sidransky

LKB1/STK11 suppresses cyclooxygenase-2 induction and cellular invasion through PEA3 in lung cancer.
Cancer research 2006;66(16):7870-9.
139.
2006

A Chatterjee; E Mambo; D Sidransky

Mitochondrial DNA mutations in human cancer.
Oncogene 2006;25(34):4663-74.
140.
2006

Mohammad Obaidul Hoque; Shahnaz Begum; Ozlem Topaloglu; Aditi Chatterjee; Eli Rosenbaum; Wim Van Criekinge; William H Westra; Mark Schoenberg; Marianna Zahurak; Steven N Goodman; et al.

Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection.
Journal of the National Cancer Institute 2006;98(14):996-1004.
141.
2006

Mohammad Obaidul Hoque; Jean-Charles Soria; Janghee Woo; Taekyeol Lee; Juna Lee; Se Jin Jang; Sunil Upadhyay; Barry Trink; Constance Monitto; Chantal Desmaze; et al.

Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth.
The American journal of pathology 2006;168(4):1345-53.
142.
2006

Myoung Sook Kim; Keishi Yamashita; Jin Hyen Baek; Hannah Lui Park; Andre Lopes Carvalho; Motonobu Osada; Mohammad Obaidul Hoque; Sunil Upadhyay; Masaki Mori; Chulso Moon; et al.

N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer.
Cancer research 2006;66(7):3409-18.
143.
2006

Keishi Yamashita; Hannah Lui Park; Myoung Sook Kim; Motonobu Osada; Yutaka Tokumaru; Hiroshi Inoue; Masaki Mori; David Sidransky

PGP9.5 methylation in diffuse-type gastric cancer.
Cancer research 2006;66(7):3921-7.
144.
2006

Wei-Wen Jiang; Eli Rosenbaum; Elizabeth Mambo; Marianna Zahurak; Brett Masayesva; Andre Lopes Carvalho; Shaoyu Zhou; William H Westra; Anthony J Alberg; David Sidransky; et al.

Decreased mitochondrial DNA content in posttreatment salivary rinses from head and neck cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1564-9.
145.
2006

Michael M Kim; Chad A Glazer; Elizabeth Mambo; Aditi Chatterjee; Ming Zhao; David Sidransky; Joseph A Califano

Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO.
Oral oncology 2006;42(2):201-7.
146.
2006

Motonobu Osada; Hannah Lui Park; Yuichi Nagakawa; Shahnaz Begum; Keishi Yamashita; Guojun Wu; Myoung Sook Kim; Barry Trink; David Sidransky

A novel response element confers p63- and p73-specific activation of the WNT4 promoter.
Biochemical and biophysical research communications 2006;339(4):1120-8.
147.
2006

Guoping Sui; Shaoyu Zhou; Jean Wang; Marcia Canto; Edward E Lee; James R Eshleman; Elizabeth A Montgomery; David Sidransky; Joseph A Califano; Anirban Maitra

Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer.
Molecular cancer 2006;5():73.
148.
2006

Edward Ratovitski; Barry Trink; David Sidransky

p63 and p73: teammates or adversaries?
Cancer cell 2006;9(1):1-2.
149.
2006

Brett G Masayesva; Elizabeth Mambo; Rodney J Taylor; Olga G Goloubeva; Shaoyu Zhou; Yoram Cohen; Khalid Minhas; Wayne Koch; James Sciubba; Anthony J Alberg; et al.

Mitochondrial DNA content increase in response to cigarette smoking.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(1):19-24.
150.
2006

Rui Henrique; Carmen Jerónimo; Manuel R Teixeira; Mohammad O Hoque; André L Carvalho; Irene Pais; Franclim R Ribeiro; Jorge Oliveira; Carlos Lopes; David Sidransky

Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.
Molecular cancer research : MCR 2006;4(1):1-8.
151.
2006

Aditi Chatterjee; Elizabeth Mambo; Motonobu Osada; Sunil Upadhyay; David Sidransky

The effect of p53-RNAi and p53 knockout on human 8-oxoguanine DNA glycosylase (hOgg1) activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):112-4.
152.
2006

Shuiying Hu; Marge Ewertz; Ralph P Tufano; Mariana Brait; Andre Lopes Carvalho; Dingxie Liu; Anthony P Tufaro; Shehzad Basaria; David S Cooper; David Sidransky; et al.

Detection of serum deoxyribonucleic acid methylation markers: a novel diagnostic tool for thyroid cancer.
The Journal of clinical endocrinology and metabolism 2006;91(1):98-104.
153.
2006

Aditi Chatterjee; Elizabeth Mambo; Yonggang Zhang; Theodore Deweese; David Sidransky

Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.
BMC cancer 2006;6():235.
154.
2005

Mingzhao Xing; William H Westra; Ralph P Tufano; Yoram Cohen; Eli Rosenbaum; Kerry J Rhoden; Kathryn A Carson; Vasily Vasko; Alexandr Larin; Giovanni Tallini; et al.

BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2005;90(12):6373-9.
155.
2005

Eli Rosenbaum; Mohammad Obaidul Hoque; Yoram Cohen; Marianna Zahurak; Mario A Eisenberger; Jonathan I Epstein; Alan W Partin; David Sidransky

Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(23):8321-5.
156.
2005

Ming Zhao; Eli Rosenbaum; Andre Lopes Carvalho; Wayne Koch; Weiwen Jiang; David Sidransky; Joseph Califano

Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer.
International journal of cancer. Journal international du cancer 2005;117(4):605-10.
157.
2005

Elizabeth Mambo; Aditi Chatterjee; Mingzhao Xing; Giovanni Tallini; Bryan R Haugen; Sai-Ching J Yeung; Saraswati Sukumar; David Sidransky

Tumor-specific changes in mtDNA content in human cancer.
International journal of cancer. Journal international du cancer 2005;116(6):920-4.
158.
2005

Rachel Zangen; Edward Ratovitski; David Sidransky

DeltaNp63alpha levels correlate with clinical tumor response to cisplatin.
Cell cycle (Georgetown, Tex.) 2005;4(10):1313-5.
159.
2005

Mohammad Obaidul Hoque; Ozlem Topaloglu; Shahnaz Begum; Rui Henrique; Eli Rosenbaum; Wim Van Criekinge; William H Westra; David Sidransky

Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(27):6569-75.
160.
2005

Nitza Goldenberg-Cohen; Yoram Cohen; Eli Rosenbaum; Zvi Herscovici; Itay Chowers; Dov Weinberger; Jacob Pe'er; David Sidransky

T1799A BRAF mutations in conjunctival melanocytic lesions.
Investigative ophthalmology & visual science 2005;46(9):3027-30.
161.
2005

Guojun Wu; Elizabeth Mambo; Zhongmin Guo; Shuiying Hu; Xin Huang; Susanne M Gollin; Barry Trink; Paul W Ladenson; David Sidransky; Mingzhao Xing

Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors.
The Journal of clinical endocrinology and metabolism 2005;90(8):4688-93.
162.
2005

M O Hoque; E Rosenbaum; W H Westra; M Xing; P Ladenson; M A Zeiger; D Sidransky; C B Umbricht

Quantitative assessment of promoter methylation profiles in thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 2005;90(7):4011-8.
163.
2005

Eli Rosenbaum; Gregory Hosler; Marianna Zahurak; Yoram Cohen; David Sidransky; William H Westra

Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(7):898-902.
164.
2005

Motonobu Osada; Yuichi Nagakawa; Hannah Lui Park; Keishi Yamashita; Guojun Wu; Myoung Sook Kim; Alexey Fomenkov; Barry Trink; David Sidransky

p63-specific activation of the BPAG-1e promoter.
The Journal of investigative dermatology 2005;125(1):52-60.
165.
2005

Motonobu Osada; Hannah Lui Park; Yuichi Nagakawa; Keishi Yamashita; Alexey Fomenkov; Myoung Sook Kim; Guojun Wu; Shuji Nomoto; Barry Trink; David Sidransky

Differential recognition of response elements determines target gene specificity for p53 and p63.
Molecular and cellular biology 2005;25(14):6077-89.
166.
2005

Elizabeth Mambo; Aditi Chatterjee; Nadja C de Souza-Pinto; Sabine Mayard; Barbara A Hogue; Mohammad O Hoque; Miral Dizdaroglu; Vilhelm A Bohr; David Sidransky

Oxidized guanine lesions and hOgg1 activity in lung cancer.
Oncogene 2005;24(28):4496-508.
167.
2005

Diana L Mandelker; Keishi Yamashita; Yutaka Tokumaru; Koshi Mimori; David L Howard; Yoichi Tanaka; Andre Lopes Carvalho; Wei-Wen Jiang; Hannah Lui Park; Myoung Sook Kim; et al.

PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma.
Cancer research 2005;65(11):4963-8.
168.
2005

Myoung Sook Kim; Jin Hyen Baek; Devulapalli Chakravarty; David Sidransky; France Carrier

Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA).
Experimental cell research 2005;306(1):94-102.
169.
2005

Rui Henrique; Carmen Jerónimo; Mohammad O Hoque; Shuji Nomoto; André L Carvalho; Vera L Costa; Jorge Oliveira; Manuel R Teixeira; Carlos Lopes; David Sidransky

MT1G hypermethylation is associated with higher tumor stage in prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1274-8.
170.
2005

John P Jakupciak; Wendy Wang; Maura E Markowitz; Delphine Ally; Michael Coble; Sudhir Srivastava; Anirban Maitra; Peter E Barker; David Sidransky; Catherine D O'Connell

Mitochondrial DNA as a cancer biomarker.
The Journal of molecular diagnostics : JMD 2005;7(2):258-67.
171.
2005

Nicole E Benoit; David Goldenberg; Shirley X Deng; Eli Rosenbaum; Yoram Cohen; Joseph A Califano; William H Shackelford; Xiao B Wang; David Sidransky

Colorimetric approach to high-throughput mutation analysis.
BioTechniques 2005;38(4):635-9.
172.
2005

Rui Henrique; Carmen Jerónimo; Mohammad O Hoque; André L Carvalho; Jorge Oliveira; Manuel R Teixeira; Carlos Lopes; David Sidransky

Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions.
DNA and cell biology 2005;24(4):264-9.
173.
2005

Andrea L Russo; Arunthathi Thiagalingam; Hongjie Pan; Joseph Califano; Kuang-hung Cheng; Jose F Ponte; Dharmaraj Chinnappan; Pratima Nemani; David Sidransky; Sam Thiagalingam

Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2466-70.
174.
2005

Wei-Wen Jiang; Brett Masayesva; Marianna Zahurak; Andre Lopes Carvalho; Eli Rosenbaum; Elizabeth Mambo; Shaoyu Zhou; Khalid Minhas; Nicole Benoit; William H Westra; et al.

Increased mitochondrial DNA content in saliva associated with head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2486-91.
175.
2005

Hongjie Pan; Joseph Califano; Jose F Ponte; Andrea L Russo; Kuang-hung Cheng; Arunthathi Thiagalingam; Pratima Nemani; David Sidransky; Sam Thiagalingam

Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer.
Cancer research 2005;65(5):1664-9.
176.
2005

Brett G Masasyesva; Betty C Tong; Malcolm V Brock; Thomas Pilkington; David Goldenberg; David Sidransky; Susan Harden; William H Westra; Joseph Califano

Molecular margin analysis predicts local recurrence after sublobar resection of lung cancer.
International journal of cancer. Journal international du cancer 2005;113(6):1022-5.
177.
2005

Jon M Davison; Eli Rosenbaum; Terry L Barrett; David Goldenberg; Mohammad O Hoque; David Sidransky; William H Westra

Absence of V599E BRAF mutations in desmoplastic melanomas.
Cancer 2005;103(4):788-92.
178.
2005

Guojun Wu; Motonobu Osada; Zhongmin Guo; Alexey Fomenkov; Shahnaz Begum; Ming Zhao; Sunil Upadhyay; Mingzhao Xing; Feng Wu; Chulso Moon; et al.

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer.
Cancer research 2005;65(3):758-66.
179.
2005

Guojun Wu; Mingzhao Xing; Elizabeth Mambo; Xin Huang; Junwei Liu; Zhongmin Guo; Aditi Chatterjee; David Goldenberg; Susanne M Gollin; Saraswati Sukumar; et al.

Somatic mutation and gain of copy number of PIK3CA in human breast cancer.
Breast cancer research : BCR 2005;7(5):R609-16.
180.
2005

John Costanzi; David Sidransky; Ami Navon; Howard Goldsweig

Ribonucleases as a novel pro-apoptotic anticancer strategy: review of the preclinical and clinical data for ranpirnase.
Cancer investigation 2005;23(7):643-50.
181.
2004

Carmen Jerónimo; Rui Henrique; Mohammad O Hoque; Elizabeth Mambo; Franclim R Ribeiro; Graça Varzim; Jorge Oliveira; Manuel R Teixeira; Carlos Lopes; David Sidransky

A quantitative promoter methylation profile of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8472-8.
182.
2004

Yan Xiao; Constance L Monitto; Khalid M Minhas; David Sidransky

Lactoferrin down-regulates G1 cyclin-dependent kinases during growth arrest of head and neck cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8683-6.
183.
2004

Yi-Ping Huang; Guojun Wu; Zhongmin Guo; Motonobu Osada; Tanya Fomenkov; Hannah Lui Park; Barry Trink; David Sidransky; Alexey Fomenkov; Edward A Ratovitski

Altered sumoylation of p63alpha contributes to the split-hand/foot malformation phenotype.
Cell cycle (Georgetown, Tex.) 2004;3(12):1587-96.
184.
2004

David Goldenberg; Juna Lee; Wayne M Koch; Michael M Kim; Barry Trink; David Sidransky; Chul-So Moon

Habitual risk factors for head and neck cancer.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004;131(6):986-93.
185.
2004

David Goldenberg; Eli Rosenbaum; Pedram Argani; Ignacio I Wistuba; David Sidransky; Paul J Thuluvath; Manuel Hidalgo; Joseph Califano; Anirban Maitra

The V599E BRAF mutation is uncommon in biliary tract cancers.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(11):1386-91.
186.
2004

Shahnaz Begum; Eli Rosenbaum; Rui Henrique; Yoram Cohen; David Sidransky; William H Westra

BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(11):1359-63.
187.
2004

Genevieve A Andrews; Sichuan Xi; Rebecca G Pomerantz; Charles J Lin; William E Gooding; Abbey L Wentzel; Li Wu; David Sidransky; Jennifer Rubin Grandis

Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis.
Head & neck 2004;26(10):870-7.
188.
2004

Alexey Fomenkov; Rachel Zangen; Yi-Ping Huang; Motonobu Osada; Zhongmin Guo; Tanya Fomenkov; Barry Trink; David Sidransky; Edward A Ratovitski

RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage.
Cell cycle (Georgetown, Tex.) 2004;3(10):1285-95.
189.
2004

Pedro P Medina; Julian Carretero; Mario F Fraga; Manel Esteller; David Sidransky; Montserrat Sanchez-Cespedes

Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.
Genes, chromosomes & cancer 2004;41(2):170-7.
190.
2004

Yutaka Tokumaru; Keishi Yamashita; Motonobu Osada; Shuji Nomoto; Dong-Il Sun; Yan Xiao; Mohammad Obaidul Hoque; William H Westra; Joseph A Califano; David Sidransky

Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing.
Cancer research 2004;64(17):5982-7.
191.
2004

Constance L Monitto; Seung-Myung Dong; Jin Jen; David Sidransky

Characterization of a human homologue of proteolysis-inducing factor and its role in cancer cachexia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5862-9.
192.
2004

Yutaka Tokumaru; Susan V Harden; Dong-Il Sun; Keishi Yamashita; Jonathan I Epstein; David Sidransky

Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5518-22.
193.
2004

Homaira Nawroz-Danish; Claus F Eisenberger; George H Yoo; Li Wu; Wayne Koch; Carri Black; John F Ensley; Wei-Zen Wei; David Sidransky

Microsatellite analysis of serum DNA in patients with head and neck cancer.
International journal of cancer. Journal international du cancer 2004;111(1):96-100.
194.
2004

Mohammad Obaidul Hoque; Shahnaz Begum; Ozlem Topaloglu; Carmen Jeronimo; Elizabeth Mambo; William H Westra; J A Califano; David Sidransky

Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer.
Cancer research 2004;64(15):5511-7.
195.
2004

Carmen Jerónimo; Rui Henrique; Mohammad O Hoque; Franclim R Ribeiro; Jorge Oliveira; Daniel Fonseca; Manuel R Teixeira; Carlos Lopes; David Sidransky

Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4010-4.
196.
2004

Brett G Masayesva; Patrick Ha; Elizabeth Garrett-Mayer; Thomas Pilkington; Rong Mao; Jonathan Pevsner; Traci Speed; Nicole Benoit; Chul-So Moon; David Sidransky; et al.

Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(23):8715-20.
197.
2004

David Goldenberg; Nicole E Benoit; Shahnaz Begum; William H Westra; Yoram Cohen; Wayne M Koch; David Sidransky; Joseph A Califano

Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction.
The Laryngoscope 2004;114(6):1027-31.
198.
2004

Mingzhao Xing; Ralph P Tufano; Anthony P Tufaro; Shehzad Basaria; Marge Ewertz; Eli Rosenbaum; Patrick J Byrne; James Wang; David Sidransky; Paul W Ladenson

Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2004;89(6):2867-72.
199.
2004

Ming Zhou; Yutaka Tokumaru; David Sidransky; Jonathan I Epstein

Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies.
The Journal of urology 2004;171(6 Pt 1):2195-8.
200.
2004

Yoram Cohen; Eli Rosenbaum; Shahnaz Begum; David Goldenberg; Clemens Esche; Ofer Lavie; David Sidransky; William H Westra

Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3444-7.
201.
2004

Nathalie Reesink-Peters; G Bea A Wisman; Carmen Jéronimo; C Yutaka Tokumaru; Yoram Cohen; Seung Myung Dong; Harrie G Klip; Henk J Buikema; Albert J H Suurmeijer; Harrie Hollema; et al.

Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: a feasibility study.
Molecular cancer research : MCR 2004;2(5):289-95.
202.
2004

Anirban Maitra; Yoram Cohen; Susannah E D Gillespie; Elizabeth Mambo; Noriyoshi Fukushima; Mohammad O Hoque; Nila Shah; Michael Goggins; Joseph Califano; David Sidransky; et al.

The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.
Genome research 2004;14(5):812-9.
203.
2004

Yoram Cohen; Eli Rosenbaum; Douglas P Clark; Martha A Zeiger; Christopher B Umbricht; Ralph P Tufano; David Sidransky; William H Westra

Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2761-5.
204.
2004

Zhongmin Guo; Jürgen F Linn; Guojun Wu; Sarah L Anzick; Claus F Eisenberger; Sarel Halachmi; Yoram Cohen; Alexey Fomenkov; Mohammad Obaidul Hoque; Kenji Okami; et al.

CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer.
Nature medicine 2004;10(4):374-81.
205.
2004

Betty C Tong; Karan Dhir; Patrick K Ha; William H Westra; Blanche P Alter; David Sidransky; Wayne M Koch; Joseph A Califano

Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity.
Head & neck 2004;26(4):345-52.
206.
2004

Ozlem Topaloglu; Mohammad Obaidul Hoque; Yutaka Tokumaru; Juna Lee; Edward Ratovitski; David Sidransky; Chul-so Moon

Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2284-8.
207.
2004

Susan V Harden; David C Thomas; Nicole Benoit; Khalid Minhas; William H Westra; Joseph A Califano; Wayne Koch; David Sidransky

Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2379-85.
208.
2004

Wayne Koch; David Sidransky

Molecular markers of radiation effectiveness in head and neck squamous cell carcinoma.
Seminars in radiation oncology 2004;14(2):130-8.
209.
2004

Chulso Moon; Raphael Rousseau; Jean-Charles Soria; Mohammad Obaidul Hoque; Juna Lee; Se Jin Jang; Barry Trink; David Sidransky; Li Mao

Aquaporin expression in human lymphocytes and dendritic cells.
American journal of hematology 2004;75(3):128-33.
210.
2004

Mingzhao Xing; Yoram Cohen; Elizabeth Mambo; Giovanni Tallini; Robert Udelsman; Paul W Ladenson; David Sidransky

Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.
Cancer research 2004;64(5):1664-8.
211.
2004

Claudine Isaacs; Luciane R Cavalli; Yoram Cohen; Marie Pennanen; Lalita K Shankar; Matthew Freedman; Baljit Singh; Minetta Liu; Ann Gallagher; Janice D Rone; et al.

Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients.
Breast cancer research and treatment 2004;84(2):99-105.
212.
2004

M Xing; V Vasko; G Tallini; A Larin; Gujun Wu; R Udelsman; M D Ringel; P W Ladenson; D Sidransky

BRAF T1796A transversion mutation in various thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 2004;89(3):1365-8.
213.
2004

David Goldenberg; Susan Harden; Brett G Masayesva; Patrick Ha; Nicole Benoit; William H Westra; Wayne M Koch; David Sidransky; Joseph A Califano

Intraoperative molecular margin analysis in head and neck cancer.
Archives of otolaryngology--head & neck surgery 2004;130(1):39-44.
214.
2003

Paola Parrella; Vito M Fazio; Antonietta P Gallo; David Sidransky; Shannath L Merbs

Fine mapping of chromosome 3 in uveal melanoma: identification of a minimal region of deletion on chromosomal arm 3p25.1-p25.2.
Cancer research 2003;63(23):8507-10.
215.
2003

David Sidransky; Rafael Irizarry; Joseph A Califano; Xianbin Li; Hening Ren; Nicole Benoit; Li Mao

Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects.
Journal of the National Cancer Institute 2003;95(22):1711-7.
216.
2003

Ashok N Reddy; Wei W Jiang; Michael Kim; Nicole Benoit; Rodney Taylor; John Clinger; David Sidransky; Joseph A Califano

Death-associated protein kinase promoter hypermethylation in normal human lymphocytes.
Cancer research 2003;63(22):7694-8.
217.
2003

Susan V Harden; Harriette Sanderson; Steven N Goodman; Alan A W Partin; Patrick C Walsh; Jonathan I Epstein; David Sidransky

Quantitative GSTP1 methylation and the detection of prostate adenocarcinoma in sextant biopsies.
Journal of the National Cancer Institute 2003;95(21):1634-7.
218.
2003

Khalid M Minhas; Bhuvanesh Singh; Wei-Wen Jiang; David Sidransky; Joseph A Califano

Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2003;107(1):46-52.
219.
2003

Keishi Yamashita; Koshi Mimori; Hiroshi Inoue; Masaki Mori; David Sidransky

A tumor-suppressive role for trypsin in human cancer progression.
Cancer research 2003;63(20):6575-8.
220.
2003

Yutaka Tokumaru; Shuji Nomoto; Carmen Jerónimo; Rui Henrique; Susan Harden; Barry Trink; David Sidransky

Biallelic inactivation of the RIZ1 gene in human gastric cancer.
Oncogene 2003;22(44):6954-8.
221.
2003

Chulso Moon; Jean-Charles Soria; Se Jin Jang; Juna Lee; Mohammad Obaidul Hoque; Mathilde Sibony; Barry Trink; Yoon Soo Chang; David Sidransky; Li Mao

Involvement of aquaporins in colorectal carcinogenesis.
Oncogene 2003;22(43):6699-703.
222.
2003

Mukesh Verma; Jacob Kagan; David Sidransky; Sudhir Srivastava

Proteomic analysis of cancer-cell mitochondria.
Nature reviews. Cancer 2003;3(10):789-95.
223.
2003

Mohammad Obaidul Hoque; Juna Lee; Shahnaz Begum; Keishi Yamashita; James M Engles; Mark Schoenberg; William H Westra; David Sidransky

High-throughput molecular analysis of urine sediment for the detection of bladder cancer by high-density single-nucleotide polymorphism array.
Cancer research 2003;63(18):5723-6.
224.
2003

Mohammad Obaidul Hoque; Shahnaz Begum; Matthias Sommer; Taekyeol Lee; Barry Trink; Edward Ratovitski; David Sidransky

PUMA in head and neck cancer.
Cancer letters 2003;199(1):75-81.
225.
2003

Seung Myung Dong; Dong-Il Sun; Nicole E Benoit; Igor Kuzmin; Michael I Lerman; David Sidransky

Epigenetic inactivation of RASSF1A in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3635-40.
226.
2003

Yoram Cohen; Gad Singer; Ofer Lavie; Seung Myung Dong; Uziel Beller; David Sidransky

The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):2981-4.
227.
2003

Hassan Ghaffar; Fikret Sahin; Montserrat Sanchez-Cepedes; Gloria H Su; Marianna Zahurak; David Sidransky; William H Westra

LKB1 protein expression in the evolution of glandular neoplasia of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):2998-3003.
228.
2003

Patrick K Ha; Nicole E Benoit; Robert Yochem; James Sciubba; Marianna Zahurak; David Sidransky; Jonathan Pevsner; William H Westra; Joseph Califano

A transcriptional progression model for head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):3058-64.
229.
2003

Pedro P Medina; Steven A Ahrendt; Marina Pollan; Paloma Fernandez; David Sidransky; Montserrat Sanchez-Cespedes

Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1-185Gln variant and p53 gene mutations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(8):699-704.
230.
2003

Steven A Ahrendt; Yingchuan Hu; Martin Buta; Michael P McDermott; Nicole Benoit; Stephen C Yang; Li Wu; David Sidransky

p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study.
Journal of the National Cancer Institute 2003;95(13):961-70.
231.
2003

Paola Parrella; Rachel Zangen; David Sidransky; Theresa Nicol

Molecular analysis of peritoneal fluid in ovarian cancer patients.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003;16(7):636-40.
232.
2003

Yoram Cohen; Nitza Goldenberg-Cohen; Paola Parrella; Itay Chowers; Shannath L Merbs; Jacob Pe'er; David Sidransky

Lack of BRAF mutation in primary uveal melanoma.
Investigative ophthalmology & visual science 2003;44(7):2876-8.
233.
2003

Alexey Fomenkov; Yi-Ping Huang; Ozlem Topaloglu; Anna Brechman; Motonobo Osada; Tanya Fomenkova; Eugene Yuriditsky; Barry Trink; David Sidransky; Edward Ratovitski

P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome.
The Journal of biological chemistry 2003;278(26):23906-14.
234.
2003

Yutaka Tokumaru; Dong-Il Sun; Shuji Nomoto; Keishi Yamashita; David Sidransky

Re: Is TIG1 a new tumor suppressor in prostate cancer?
Journal of the National Cancer Institute 2003;95(12):919-20.
235.
2003

Guojun Wu; Shuji Nomoto; Mohammad Obaidul Hoque; Tatiana Dracheva; Motonabu Osada; Chyi-Chia Richard Lee; Seung Myung Dong; Zhongmin Guo; Nicole Benoit; Yoram Cohen; et al.

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development.
Cancer research 2003;63(10):2351-7.
236.
2003

Mohammad Obaidul Hoque; Chyi-Chia R Lee; Paul Cairns; Mark Schoenberg; David Sidransky

Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis.
Cancer research 2003;63(9):2216-22.
237.
2003

Mingzhao Xing; Yutaka Tokumaru; Guojun Wu; William B Westra; Paul W Ladenson; David Sidransky

Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis.
Cancer research 2003;63(9):2312-5.
238.
2003

Mingzhao Xing; Henning Usadel; Yoram Cohen; Yutaka Tokumaru; Zhongmin Guo; William B Westra; Betty C Tong; Giovanni Tallini; Robert Udelsman; Joseph A Califano; et al.

Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing.
Cancer research 2003;63(9):2316-21.
239.
2003

Yoram Cohen; Mingzhao Xing; Elizabeth Mambo; Zhongmin Guo; Guogun Wu; Barry Trink; Uziel Beller; William H Westra; Paul W Ladenson; David Sidransky

BRAF mutation in papillary thyroid carcinoma.
Journal of the National Cancer Institute 2003;95(8):625-7.
240.
2003

Susan V Harden; Yutaka Tokumaru; William H Westra; Steven Goodman; Steven A Ahrendt; Stephen C Yang; David Sidransky

Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1370-5.
241.
2003

Gad Singer; Robert Oldt; Yoram Cohen; Brant G Wang; David Sidransky; Robert J Kurman; Ie-Ming Shih

Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma.
Journal of the National Cancer Institute 2003;95(6):484-6.
242.
2003

Betty C Tong; Patrick K Ha; Karan Dhir; Mingzhao Xing; William H Westra; David Sidransky; Joseph A Califano

Mitochondrial DNA alterations in thyroid cancer.
Journal of surgical oncology 2003;82(3):170-3.
243.
2003

Susan V Harden; Zhongmin Guo; Jonathan I Epstein; David Sidransky

Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma.
The Journal of urology 2003;169(3):1138-42.
244.
2003

Elizabeth Mambo; Xiangqun Gao; Yoram Cohen; Zhongmin Guo; Paul Talalay; David Sidransky

Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1838-43.
245.
2003

C Jerónimo; R Henrique; P F Campos; J Oliveira; O L Caballero; C Lopes; D Sidransky

Endothelin B receptor gene hypermethylation in prostate adenocarcinoma.
Journal of clinical pathology 2003;56(1):52-5.
246.
2002

Patrick K Ha; Thomas A Pilkington; William H Westra; James Sciubba; David Sidransky; Joseph A Califano

Progression of microsatellite instability from premalignant lesions to tumors of the head and neck.
International journal of cancer. Journal international du cancer 2002;102(6):615-7.
247.
2002

Carmen Jerónimo; Henning Usadel; Rui Henrique; Cristina Silva; Jorge Oliveira; Carlos Lopes; David Sidransky

Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer.
Urology 2002;60(6):1131-5.
248.
2002

Keishi Yamashita; Sunil Upadhyay; Motonobu Osada; Mohammad O Hoque; Yan Xiao; Masaki Mori; Fumiaki Sato; Stephen J Meltzer; David Sidransky

Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Cancer cell 2002;2(6):485-95.
249.
2002

Rachel Zangen; Susan Harden; Daniel Cohen; Paola Parrella; David Sidransky

Mouse mammary tumor-like env gene as a molecular marker for breast cancer?
International journal of cancer. Journal international du cancer 2002;102(3):304-7.
250.
2002

Ying Chuan Hu; David Sidransky; Steven A Ahrendt

Molecular detection approaches for smoking associated tumors.
Oncogene 2002;21(48):7289-97.
251.
2002

Seung Myung Dong; David Sidransky

Absence of ST7 gene alterations in human cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2939-41.
252.
2002

Montserrat Sanchez-Cespedes; Paola Parrella; Manel Esteller; Shuji Nomoto; Barry Trink; James M Engles; William H Westra; James G Herman; David Sidransky

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung.
Cancer research 2002;62(13):3659-62.
253.
2002

Patrick K Ha; Betty C Tong; William H Westra; Montserrat Sanchez-Cespedes; Paola Parrella; Marianna Zahurak; David Sidransky; Joseph A Califano

Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2260-5.
254.
2002

Mark L Gonzalgo; Claus F Eisenberger; Shing M Lee; Bruce J Trock; Fray F Marshall; Steven Hortopan; David Sidransky; Mark P Schoenberg

Prognostic significance of preoperative molecular serum analysis in renal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1878-81.
255.
2002

Otávia L Caballero; Vicente Resto; Meera Patturajan; Daoud Meerzaman; Ming Zhou Guo; James Engles; Robert Yochem; Edward Ratovitski; David Sidransky; Jin Jen

Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).
Oncogene 2002;21(19):3003-10.
256.
2002

Meera Patturajan; Shuji Nomoto; Matthias Sommer; Alexey Fomenkov; Kenji Hibi; Rachel Zangen; Nina Poliak; Joseph Califano; Barry Trink; Edward Ratovitski; et al.

DeltaNp63 induces beta-catenin nuclear accumulation and signaling.
Cancer cell 2002;1(4):369-79.
257.
2002

Patrick K Ha; Sara I Pai; William H Westra; Maura L Gillison; Betty C Tong; David Sidransky; Joseph A Califano

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1203-9.
258.
2002

Carmen Jerónimo; Graça Varzim; Rui Henrique; Jorge Oliveira; Maria José Bento; Cristina Silva; Carlos Lopes; David Sidransky

I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(5):445-50.
259.
2002

Hong-Lin Cheng; Barry Trink; Tzong-Shin Tzai; Hsiao-Sheng Liu; Shih-Huang Chan; Chung-Liang Ho; David Sidransky; Nan-Haw Chow

Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1544-50.
260.
2002

David Sidransky

Emerging molecular markers of cancer.
Nature reviews. Cancer 2002;2(3):210-9.
261.
2002

Steven A Ahrendt; Stephen C Yang; Li Wu; Carmen M Roig; Pamela Russell; William H Westra; Jin Jen; Malcolm V Brock; Richard F Heitmiller; David Sidransky

Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study.
The Journal of thoracic and cardiovascular surgery 2002;123(3):466-73; discussion 473-4.
262.
2002

Xiyuan Sun; K Hung; L Wu; D Sidransky; Baochuan Guo

Detection of tumor mutations in the presence of excess amounts of normal DNA.
Nature biotechnology 2002;20(2):186-9.
263.
2002

Shuji Nomoto; Katsuya Yamashita; Katsumi Koshikawa; Akimasa Nakao; David Sidransky

Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):481-7.
264.
2002

Henning Usadel; Jan Brabender; Kathy D Danenberg; Carmen Jerónimo; Susan Harden; James Engles; Peter V Danenberg; Stephen Yang; David Sidransky

Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer.
Cancer research 2002;62(2):371-5.
265.
2002

Seung Myung Dong; Sara I Pai; Seo-Hee Rha; Allan Hildesheim; Robert J Kurman; Peter E Schwartz; Rodrigue Mortel; Larry McGowan; Mitchell D Greenberg; Willard A Barnes; et al.

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(1):3-6.
266.
2002

Shuji Nomoto; Montserrant Sanchez-Cespedes; David Sidransky

Identification of mtDNA mutations in human cancer.
Methods in molecular biology (Clifton, N.J.) 2002;197():107-17.
267.
2001

A Forastiere; W Koch; A Trotti; D Sidransky

Head and neck cancer.
The New England journal of medicine 2001;345(26):1890-900.
268.
2001

M Nacht; T Dracheva; Y Gao; T Fujii; Y Chen; A Player; V Akmaev; B Cook; M Dufault; M Zhang; et al.

Molecular characteristics of non-small cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15203-8.
269.
2001

C Jerónimo; H Usadel; R Henrique; J Oliveira; C Lopes; W G Nelson; D Sidransky

Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma.
Journal of the National Cancer Institute 2001;93(22):1747-52.
270.
2001

P Wolf; Y C Hu; K Doffek; D Sidransky; S A Ahrendt

O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
Cancer research 2001;61(22):8113-7.
271.
2001

P Parrella; Y Xiao; M Fliss; M Sanchez-Cespedes; P Mazzarelli; M Rinaldi; T Nicol; E Gabrielson; C Cuomo; D Cohen; et al.

Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates.
Cancer research 2001;61(20):7623-6.
272.
2001

O L Caballero; D Cohen; Q Liu; M Esteller; J Bonacum; P White; J Engles; R Yochem; J G Herman; W H Westra; et al.

Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer.
Genes, chromosomes & cancer 2001;32(2):119-25.
273.
2001

M Sanchez-Cespedes; P Parrella; S Nomoto; D Cohen; Y Xiao; M Esteller; C Jeronimo; R C Jordan; T Nicol; W M Koch; et al.

Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors.
Cancer research 2001;61(19):7015-9.
274.
2001

S A Ahrendt; P A Decker; E A Alawi; Y R Zhu Yr; M Sanchez-Cespedes; S C Yang; G B Haasler; A Kajdacsy-Balla; M J Demeure; D Sidransky

Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung.
Cancer 2001;92(6):1525-30.
275.
2001

S L Bittencourt Rosas; O L Caballero; S M Dong; M da G da Costa Carvalho; D Sidransky; J Jen

Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissues.
Cancer letters 2001;170(1):73-9.
276.
2001

P Cairns; M Esteller; J G Herman; M Schoenberg; C Jeronimo; M Sanchez-Cespedes; N H Chow; M Grasso; L Wu; W B Westra; et al.

Molecular detection of prostate cancer in urine by GSTP1 hypermethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2727-30.
277.
2001

C Jerónimo; S Nomoto; O L Caballero; H Usadel; R Henrique; G Varzim; J Oliveira; C Lopes; M S Fliss; D Sidransky

Mitochondrial mutations in early stage prostate cancer and bodily fluids.
Oncogene 2001;20(37):5195-8.
278.
2001

S H Rha; S M Dong; J Jen; T Nicol; D Sidransky

Molecular detection of cervical intraepithelial neoplasia and cervical carcinoma by microsatellite analysis of Papanicolaou smears.
International journal of cancer. Journal international du cancer 2001;93(3):424-9.
279.
2001

P Parrella; O L Caballero; D Sidransky; S L Merbs

Detection of c-myc amplification in uveal melanoma by fluorescent in situ hybridization.
Investigative ophthalmology & visual science 2001;42(8):1679-84.
280.
2001

Z Guo; K Yamaguchi; M Sanchez-Cespedes; W H Westra; W M Koch; D Sidransky

Allelic losses in OraTest-directed biopsies of patients with prior upper aerodigestive tract malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1963-8.
281.
2001

S M Dong; H S Kim; S H Rha; D Sidransky

Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1982-6.
282.
2001

J Brabender; H Usadel; K D Danenberg; R Metzger; P M Schneider; R V Lord; K Wickramasinghe; C E Lum; J Park; D Salonga; et al.

Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival.
Oncogene 2001;20(27):3528-32.
283.
2001

T Minamoto; T Buschmann; H Habelhah; E Matusevich; H Tahara; A L Boerresen-Dale; C Harris; D Sidransky; Z Ronai

Distinct pattern of p53 phosphorylation in human tumors.
Oncogene 2001;20(26):3341-7.
284.
2001

S M Dong; G Traverso; C Johnson; L Geng; R Favis; K Boynton; K Hibi; S N Goodman; M D'Allessio; P Paty; et al.

Detecting colorectal cancer in stool with the use of multiple genetic targets.
Journal of the National Cancer Institute 2001;93(11):858-65.
285.
2001

M J Fisher; A K Virmani; L Wu; R Aplenc; J C Harper; S M Powell; T R Rebbeck; D Sidransky; A F Gazdar; W S El-Deiry

Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1688-97.
286.
2001

J W Rocco; D Sidransky

p16(MTS-1/CDKN2/INK4a) in cancer progression.
Experimental cell research 2001;264(1):42-55.
287.
2001

M Sanchez-Cespedes; P A Decker; K M Doffek; M Esteller; W H Westra; E A Alawi; J G Herman; M J Demeure; D Sidransky; S A Ahrendt

Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers.
Cancer research 2001;61(5):2092-6.
288.
2001

M F Spafford; W M Koch; A L Reed; J A Califano; L H Xu; C F Eisenberger; L Yip; P L Leong; L Wu; S X Liu; et al.

Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):607-12.
289.
2001

M Sanchez-Cespedes; S A Ahrendt; S Piantadosi; R Rosell; M Monzo; L Wu; W H Westra; S C Yang; J Jen; D Sidransky

Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers.
Cancer research 2001;61(4):1309-13.
290.
2001

E A Ratovitski; M Patturajan; K Hibi; B Trink; K Yamaguchi; D Sidransky

p53 associates with and targets Delta Np63 into a protein degradation pathway.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1817-22.
291.
2001

S L Rosas; W Koch; M G da Costa Carvalho; L Wu; J Califano; W Westra; J Jen; D Sidransky

Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients.
Cancer research 2001;61(3):939-42.
292.
2001

L Xu; J Chow; J Bonacum; C Eisenberger; S A Ahrendt; M Spafford; L Wu; S M Lee; S Piantadosi; M S Tockman; et al.

Microsatellite instability at AAAG repeat sequences in respiratory tract cancers.
International journal of cancer. Journal international du cancer 2001;91(2):200-4.
293.
2000

N H Chow; P Cairns; C F Eisenberger; M P Schoenberg; D C Taylor; J I Epstein; D Sidransky

Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer.
International journal of cancer. Journal international du cancer 2000;89(6):514-8.
294.
2000

K Yamaguchi; M Patturajan; B Trink; H Usadel; W Koch; J Jen; D Sidransky

Circulating antibodies to p40(AIS) in the sera of respiratory tract cancer patients.
International journal of cancer. Journal international du cancer 2000;89(6):524-8.
295.
2000

K Kawakami; J Brabender; R V Lord; S Groshen; B D Greenwald; M J Krasna; J Yin; A S Fleisher; J M Abraham; D G Beer; et al.

Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.
Journal of the National Cancer Institute 2000;92(22):1805-11.
296.
2000

R B Capone; S I Pai; W M Koch; M L Gillison; H N Danish; W H Westra; R Daniel; K V Shah; D Sidransky

Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4171-5.
297.
2000

V A Resto; O L Caballero; M R Buta; W H Westra; L Wu; J M Westendorf; J Jen; P Hieter; D Sidransky

A putative oncogenic role for MPP11 in head and neck squamous cell cancer.
Cancer research 2000;60(19):5529-35.
298.
2000

S I Shah; L Yip; B Greenberg; J A Califano; J Chow; C F Eisenberger; D J Lee; D A Sewell; A L Reed; M Lango; et al.

Two distinct regions of loss on chromosome arm 4q in primary head and neck squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery 2000;126(9):1073-6.
299.
2000

M Esteller; A Sparks; M Toyota; M Sanchez-Cespedes; G Capella; M A Peinado; S Gonzalez; G Tarafa; D Sidransky; S J Meltzer; et al.

Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.
Cancer research 2000;60(16):4366-71.
300.
2000

I L Medintz; C C Lee; W W Wong; K Pirkola; D Sidransky; R A Mathies

Loss of heterozygosity assay for molecular detection of cancer using energy-transfer primers and capillary array electrophoresis.
Genome research 2000;10(8):1211-8.
301.
2000

S A Ahrendt; J T Chow; S C Yang; L Wu; M J Zhang; J Jen; D Sidransky

Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer.
Cancer research 2000;60(12):3155-9.
302.
2000

K Yamaguchi; L Wu; O L Caballero; K Hibi; B Trink; V Resto; P Cairns; K Okami; W M Koch; D Sidransky; et al.

Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2000;86(5):684-9.
303.
2000

K Hibi; B Trink; M Patturajan; W H Westra; O L Caballero; D E Hill; E A Ratovitski; J Jen; D Sidransky

AIS is an oncogene amplified in squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5462-7.
304.
2000

M L Gillison; W M Koch; R B Capone; M Spafford; W H Westra; L Wu; M L Zahurak; R W Daniel; M Viglione; D E Symer; et al.

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers.
Journal of the National Cancer Institute 2000;92(9):709-20.
305.
2000

M Esteller; M Toyota; M Sanchez-Cespedes; G Capella; M A Peinado; D N Watkins; J P Issa; D Sidransky; S B Baylin; J G Herman

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Cancer research 2000;60(9):2368-71.
306.
2000

S A Ahrendt; P A Decker; K Doffek; B Wang; L Xu; M J Demeure; J Jen; D Sidransky

Microsatellite instability at selected tetranucleotide repeats is associated with p53 mutations in non-small cell lung cancer.
Cancer research 2000;60(9):2488-91.
307.
2000

D Sidransky

Circulating DNA. What we know and what we need to learn.
Annals of the New York Academy of Sciences 2000;906():1-4.
308.
2000

J Jen; L Wu; D Sidransky

An overview on the isolation and analysis of circulating tumor DNA in plasma and serum.
Annals of the New York Academy of Sciences 2000;906():8-12.
309.
2000

M S Fliss; H Usadel; O L Caballero; L Wu; M R Buta; S M Eleff; J Jen; D Sidransky

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids.
Science (New York, N.Y.) 2000;287(5460):2017-9.
310.
2000

S Halachmi; A M DeMarzo; N H Chow; N Halachmi; A E Smith; J F Linn; O Nativ; J I Epstein; M P Schoenberg; D Sidransky

Genetic alterations in urinary bladder carcinosarcoma: evidence of a common clonal origin.
European urology 2000;37(3):350-7.
311.
2000

M Sanchez-Cespedes; K Okami; P Cairns; D Sidransky

Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions.
Genes, chromosomes & cancer 2000;27(3):319-22.
312.
2000

M Sanchez-Cespedes; M Esteller; L Wu; H Nawroz-Danish; G H Yoo; W M Koch; J Jen; J G Herman; D Sidransky

Gene promoter hypermethylation in tumors and serum of head and neck cancer patients.
Cancer research 2000;60(4):892-5.
313.
2000

J Califano; W H Westra; G Meininger; R Corio; W M Koch; D Sidransky

Genetic progression and clonal relationship of recurrent premalignant head and neck lesions.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):347-52.
314.
2000

H T Lynch; R D McComb; N K Osborn; P A Wolpert; J F Lynch; Z K Wszolek; D Sidransky; R E Steg

Predominance of brain tumors in an extended Li-Fraumeni (SBLA) kindred, including a case of Sturge-Weber syndrome.
Cancer 2000;88(2):433-9.
315.
2000

J Califano; W Koch; D Sidransky; W H Westra

Inverted sinonasal papilloma : a molecular genetic appraisal of its putative status as a Precursor to squamous cell carcinoma.
The American journal of pathology 2000;156(1):333-7.
316.
2000

S A Ahrendt; A Rashid; J T Chow; C F Eisenberger; H A Pitt; D Sidransky

p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.
Journal of hepato-biliary-pancreatic surgery 2000;7(4):426-31.
317.
1999

C F Eisenberger; M Schoenberg; C Enger; S Hortopan; S Shah; N H Chow; F F Marshall; D Sidransky

Diagnosis of renal cancer by molecular urinalysis.
Journal of the National Cancer Institute 1999;91(23):2028-32.
318.
1999

M Sanchez-Cespedes; A L Reed; M Buta; L Wu; W H Westra; J G Herman; S C Yang; J Jen; D Sidransky

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer.
Oncogene 1999;18(43):5843-9.
319.
1999

W M Koch; M Lango; D Sewell; M Zahurak; D Sidransky

Head and neck cancer in nonsmokers: a distinct clinical and molecular entity.
The Laryngoscope 1999;109(10):1544-51.
320.
1999

D Taylor; W M Koch; M Zahurak; K Shah; D Sidransky; W H Westra

Immunohistochemical detection of p53 protein accumulation in head and neck cancer: correlation with p53 gene alterations.
Human pathology 1999;30(10):1221-5.
321.
1999

S A Ahrendt; D Sidransky

The potential of molecular screening.
Surgical oncology clinics of North America 1999;8(4):641-56, vi.
322.
1999

K Hibi; W H Westra; M Borges; S Goodman; D Sidransky; J Jen

PGP9.5 as a candidate tumor marker for non-small-cell lung cancer.
The American journal of pathology 1999;155(3):711-5.
323.
1999

C F Eisenberger; L Wu; T Nicol; S I Shah; D Sidransky; W H Westra

Comparative microsatellite analysis in discerning origin of disseminated tumor: the case of a patient with malignant ascites and a history of multiple tumors.
Human pathology 1999;30(9):1111-3.
324.
1999

M Sanchez-Cespedes; M Esteller; K Hibi; F O Cope; W H Westra; S Piantadosi; J G Herman; J Jen; D Sidransky

Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2450-4.
325.
1999

S G Docimo; N H Chow; G Steiner; R I Silver; R Rodriguez; S Kinsman; D Sidransky; M Schoenberg

Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.
Urology 1999;54(3):561.
326.
1999

P M Leong; C L Kauffman; J M Moresi; L Wu; C Jeronimo; D M Sidransky; S J Miller

Basal cell carcinoma-like epidermal changes overlying dermatofibromas often reveal loss of heterozygosity in the PTCH gene.
The Journal of investigative dermatology 1999;113(2):279-80.
327.
1999

P Parrella; D Sidransky; S L Merbs

Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway.
Cancer research 1999;59(13):3032-7.
328.
1999

J Califano; P L Leong; W M Koch; C F Eisenberger; D Sidransky; W H Westra

Second esophageal tumors in patients with head and neck squamous cell carcinoma: an assessment of clonal relationships.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1862-7.
329.
1999

S A Ahrendt; S Halachmi; J T Chow; L Wu; N Halachmi; S C Yang; S Wehage; J Jen; D Sidransky

Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7382-7.
330.
1999

K Okami; A L Reed; P Cairns; W M Koch; W H Westra; S Wehage; J Jen; D Sidransky

Cyclin D1 amplification is independent of p16 inactivation in head and neck squamous cell carcinoma.
Oncogene 1999;18(23):3541-5.
331.
1999

S A Ahrendt; C F Eisenberger; L Yip; A Rashid; J T Chow; H A Pitt; D Sidransky

Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma.
The Journal of surgical research 1999;84(1):88-93.
332.
1999

K Yamaguchi; K Okami; K Hibi; S L Wehage; J Jen; D Sidransky

Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines.
Cancer letters 1999;139(2):183-7.
333.
1999

J Califano; W H Westra; W Koch; G Meininger; A Reed; L Yip; J O Boyle; F Lonardo; D Sidransky

Unknown primary head and neck squamous cell carcinoma: molecular identification of the site of origin.
Journal of the National Cancer Institute 1999;91(7):599-604.
334.
1999

P Cairns; D Sidransky

Molecular methods for the diagnosis of cancer.
Biochimica et biophysica acta 1999;1423(2):C11-8.
335.
1999

R Anbazhagan; A Merlo; D Sidransky; E Gabrielson

Absence of intragenic mismatch mutations in small cell lung cancers with microsatellite instability.
International journal of cancer. Journal international du cancer 1999;80(6):944-5.
336.
1999

S L Merbs; D Sidransky

Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma.
Investigative ophthalmology & visual science 1999;40(3):779-83.
337.
1999

S A Ahrendt; J T Chow; L H Xu; S C Yang; C F Eisenberger; M Esteller; J G Herman; L Wu; P A Decker; J Jen; et al.

Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer.
Journal of the National Cancer Institute 1999;91(4):332-9.
338.
1999

M Esteller; M Sanchez-Cespedes; R Rosell; D Sidransky; S B Baylin; J G Herman

Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.
Cancer research 1999;59(1):67-70.
339.
1998

K Hibi; Q Liu; G A Beaudry; S L Madden; W H Westra; S L Wehage; S C Yang; R F Heitmiller; A H Bertelsen; D Sidransky; et al.

Serial analysis of gene expression in non-small cell lung cancer.
Cancer research 1998;58(24):5690-4.
340.
1998

M Sanchez-Cespedes; P Cairns; J Jen; D Sidransky

Degenerate oligonucleotide-primed PCR (DOP-PCR): evaluation of its reliability for screening of genetic alterations in neoplasia.
BioTechniques 1998;25(6):1036-8.
341.
1998

L A Baker; N H Chow; S G Docimo; J P Gearhart; D Sidransky; M P Schoenberg

Microsatellite deoxyribonucleic acid analysis to detect bladder cancer in bladder exstrophy.
The Journal of urology 1998;160(6 Pt 1):2192-3.
342.
1998

C R Boland; S N Thibodeau; S R Hamilton; D Sidransky; J R Eshleman; R W Burt; S J Meltzer; M A Rodriguez-Bigas; R Fodde; G N Ranzani; et al.

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.
Cancer research 1998;58(22):5248-57.
343.
1998

N Halachmi; S Halachmi; E Evron; P Cairns; K Okami; M Saji; W H Westra; M A Zeiger; J Jen; D Sidransky

Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors.
Genes, chromosomes & cancer 1998;23(3):239-43.
344.
1998

W H Westra; D Sidransky

Phenotypic and genotypic disparity in premalignant lesions: of calm water and crocodiles.
Journal of the National Cancer Institute 1998;90(20):1500-1.
345.
1998

S I Pai; G S Wu; N Ozören; L Wu; J Jen; D Sidransky; W S El-Deiry

Rare loss-of-function mutation of a death receptor gene in head and neck cancer.
Cancer research 1998;58(16):3513-8.
346.
1998

H M Nawroz-Danish; W M Koch; W H Westra; G Yoo; D Sidransky

Lack of BRCA2 alterations in primary head and neck squamous cell carcinoma.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1998;119(1):21-5.
347.
1998

J W Rocco; D Li; W H Liggett; L Duan; J K Saunders; D Sidransky; B W O'Malley

p16INK4A adenovirus-mediated gene therapy for human head and neck squamous cell cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(7):1697-704.
348.
1998

B Trink; K Okami; L Wu; V Sriuranpong; J Jen; D Sidransky

A new human p53 homologue.
Nature medicine 1998;4(7):747-8.
349.
1998

P P Leong; B Rezai; W M Koch; A Reed; D Eisele; D J Lee; D Sidransky; J Jen; W H Westra

Distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma.
Journal of the National Cancer Institute 1998;90(13):972-7.
350.
1998

P Cairns; E Evron; K Okami; N Halachmi; M Esteller; J G Herman; S Bose; S I Wang; R Parsons; D Sidransky

Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers.
Oncogene 1998;16(24):3215-8.
351.
1998

B Trink; S I Pai; S L Spunt; V Raman; P Cairns; J Jen; E Gabrielson; S Sukumar; D Sidransky

Absence of TSG101 transcript abnormalities in human cancers.
Oncogene 1998;16(21):2815-8.
352.
1998

K Hibi; C R Robinson; S Booker; L Wu; S R Hamilton; D Sidransky; J Jen

Molecular detection of genetic alterations in the serum of colorectal cancer patients.
Cancer research 1998;58(7):1405-7.
353.
1998

W H Liggett; D Sidransky

Role of the p16 tumor suppressor gene in cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(3):1197-206.
354.
1998

J P Cairns; P W Chiang; S Ramamoorthy; D M Kurnit; D Sidransky

A comparison between microsatellite and quantitative PCR analyses to detect frequent p16 copy number changes in primary bladder tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):441-4.
355.
1998

K Okami; L Wu; G Riggins; P Cairns; M Goggins; E Evron; N Halachmi; S A Ahrendt; A L Reed; W Hilgers; et al.

Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.
Cancer research 1998;58(3):509-11.
356.
1998

H Suzuki; D Freije; D R Nusskern; K Okami; P Cairns; D Sidransky; W B Isaacs; G S Bova

Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues.
Cancer research 1998;58(2):204-9.
357.
1997

K Okami; P Cairns; W H Westra; J F Linn; S A Ahrendt; L Wu; D Sidransky; J Jen

Detailed deletion mapping at chromosome 9p21 in non-small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization.
International journal of cancer. Journal international du cancer 1997;74(6):588-92.
358.
1997

J F Linn; M Lango; S Halachmi; M P Schoenberg; D Sidransky

Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients.
International journal of cancer. Journal international du cancer 1997;74(6):625-9.
359.
1997

P Cairns; K Okami; P King; J Bonacum; S Ahrendt; L Wu; L Mao; J Jen; D Sidransky

Genomic organization and mutation analysis of Hel-N1 in lung cancers with chromosome 9p21 deletions.
Cancer research 1997;57(23):5356-9.
360.
1997

P Cairns; K Okami; S Halachmi; N Halachmi; M Esteller; J G Herman; J Jen; W B Isaacs; G S Bova; D Sidransky

Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.
Cancer research 1997;57(22):4997-5000.
361.
1997

D Sidransky

Nucleic acid-based methods for the detection of cancer.
Science (New York, N.Y.) 1997;278(5340):1054-9.
362.
1997

W Arap; E Knudsen; D A Sewell; D Sidransky; J Y Wang; H J Huang; W K Cavenee

Functional analysis of wild-type and malignant glioma derived CDKN2Abeta alleles: evidence for an RB-independent growth suppressive pathway.
Oncogene 1997;15(17):2013-20.
363.
1997

S I Wang; J Puc; J Li; J N Bruce; P Cairns; D Sidransky; R Parsons

Somatic mutations of PTEN in glioblastoma multiforme.
Cancer research 1997;57(19):4183-6.
364.
1997

Y Wang; S C Hung; J F Linn; G Steiner; A N Glazer; D Sidransky; R A Mathies

Microsatellite-based cancer detection using capillary array electrophoresis and energy-transfer fluorescent primers.
Electrophoresis 1997;18(10):1742-9.
365.
1997

E Evron; P Cairns; N Halachmi; S A Ahrendt; A L Reed; D Sidransky

Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene.
Cancer research 1997;57(14):2888-9.
366.
1997

S A Ahrendt; S C Yang; L Wu; W H Westra; J Jen; J A Califano; D Sidransky

Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(7):1207-14.
367.
1997

D F Jarrard; G S Bova; C M Ewing; S S Pin; S H Nguyen; S B Baylin; P Cairns; D Sidransky; J G Herman; W B Isaacs

Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer.
Genes, chromosomes & cancer 1997;19(2):90-6.
368.
1997

G Steiner; M P Schoenberg; J F Linn; L Mao; D Sidransky

Detection of bladder cancer recurrence by microsatellite analysis of urine.
Nature medicine 1997;3(6):621-4.
369.
1997

D J Lee; W M Koch; G Yoo; M Lango; A Reed; J Califano; J A Brennan; W H Westra; M Zahurak; D Sidransky

Impact of chromosome 14q loss on survival in primary head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(4):501-5.
370.
1997

J S Wiest; W A Franklin; J T Otstot; K Forbey; M Varella-Garcia; K Rao; H Drabkin; R Gemmill; S Ahrent; D Sidransky; et al.

Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene.
Cancer research 1997;57(1):1-6.
371.
1997

J S Wiest; W A Franklin; H Drabkin; R Gemmill; D Sidransky; M W Anderson

Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention.
Journal of cellular biochemistry. Supplement 1997;28-29():64-73.
372.
1996

J A Califano; M M Johns; W H Westra; M N Lango; D Eisele; M Saji; M A Zeiger; R Udelsman; W M Koch; D Sidransky

An allelotype of papillary thyroid cancer.
International journal of cancer. Journal international du cancer 1996;69(6):442-4.
373.
1996

J Califano; S A Ahrendt; G Meininger; W H Westra; W M Koch; D Sidransky

Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Cancer research 1996;56(24):5720-2.
374.
1996

G Steiner; D Sidransky

Molecular differential diagnosis of renal carcinoma: from microscopes to microsatellites.
The American journal of pathology 1996;149(6):1791-5.
375.
1996

W M Koch; J A Brennan; M Zahurak; S N Goodman; W H Westra; D Schwab; G H Yoo; D J Lee; A A Forastiere; D Sidransky

p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma.
Journal of the National Cancer Institute 1996;88(21):1580-6.
376.
1996

C A Moskaluk; R Heitmiller; M Zahurak; D Schwab; D Sidransky; S R Hamilton

p53 and p21(WAF1/CIP1/SDI1) gene products in Barrett esophagus and adenocarcinoma of the esophagus and esophagogastric junction.
Human pathology 1996;27(11):1211-20.
377.
1996

G Steiner; P Cairns; T J Polascik; F F Marshall; J I Epstein; D Sidransky; M Schoenberg

High-density mapping of chromosomal arm 1q in renal collecting duct carcinoma: region of minimal deletion at 1q32.1-32.2.
Cancer research 1996;56(21):5044-6.
378.
1996

S L Yao; A J Akhtar; K A McKenna; G C Bedi; D Sidransky; M Mabry; R Ravi; M I Collector; R J Jones; S J Sharkis; et al.

Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase.
Nature medicine 1996;2(10):1140-3.
379.
1996

W H Liggett; D A Sewell; J Rocco; S A Ahrendt; W Koch; D Sidransky

p16 and p16 beta are potent growth suppressors of head and neck squamous carcinoma cells in vitro.
Cancer research 1996;56(18):4119-23.
380.
1996

H Nawroz; W Koch; P Anker; M Stroun; D Sidransky

Microsatellite alterations in serum DNA of head and neck cancer patients.
Nature medicine 1996;2(9):1035-7.
381.
1996

D Sidransky

Is human patched the gatekeeper of common skin cancers?
Nature genetics 1996;14(1):7-8.
382.
1996

D Sidransky

Advances in cancer detection.
Scientific American 1996;275(3):104-9.
383.
1996

A L Reed; J Califano; P Cairns; W H Westra; R M Jones; W Koch; S Ahrendt; Y Eby; D Sewell; H Nawroz; et al.

High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma.
Cancer research 1996;56(16):3630-3.
384.
1996

M P Rosin; S J Miller; D Schwab; W H Westra; D Sidransky

Molecular analysis of effectiveness of Mohs' surgical technique.
Lancet 1996;347(9016):1692-3.
385.
1996

G C Bedi; W H Westra; E Gabrielson; W Koch; D Sidransky

Multiple head and neck tumors: evidence for a common clonal origin.
Cancer research 1996;56(11):2484-7.
386.
1996

J Califano; P van der Riet; W Westra; H Nawroz; G Clayman; S Piantadosi; R Corio; D Lee; B Greenberg; W Koch; et al.

Genetic progression model for head and neck cancer: implications for field cancerization.
Cancer research 1996;56(11):2488-92.
387.
1996

M Schutte; R H Hruban; L Hedrick; K R Cho; G M Nadasdy; C L Weinstein; G S Bova; W B Isaacs; P Cairns; H Nawroz; et al.

DPC4 gene in various tumor types.
Cancer research 1996;56(11):2527-30.
388.
1996

D Sidransky

Two tracks but one race? Cancer genetics.
Current biology : CB 1996;6(5):523-5.
389.
1996

T J Polascik; P Cairns; J I Epstein; L Fuzesi; J Y Ro; F F Marshall; D Sidransky; M Schoenberg

Distal nephron renal tumors: microsatellite allelotype.
Cancer research 1996;56(8):1892-5.
390.
1996

H Fujii; C Marsh; P Cairns; D Sidransky; E Gabrielson

Genetic divergence in the clonal evolution of breast cancer.
Cancer research 1996;56(7):1493-7.
391.
1996

M Schoenberg; L Kiemeney; P C Walsh; C A Griffin; D Sidransky

Germline translocation t(5;20)(p15;q11) and familial transitional cell carcinoma.
The Journal of urology 1996;155(3):1035-6.
392.
1996

M M Johns; W H Westra; J A Califano; D Eisele; W M Koch; D Sidransky

Allelotype of salivary gland tumors.
Cancer research 1996;56(5):1151-4.
393.
1996

J A Brennan; D Sidransky

Molecular staging of head and neck squamous carcinoma.
Cancer metastasis reviews 1996;15(1):3-10.
394.
1996

L Mao; M P Schoenberg; M Scicchitano; Y S Erozan; A Merlo; D Schwab; D Sidransky

Molecular detection of primary bladder cancer by microsatellite analysis.
Science (New York, N.Y.) 1996;271(5249):659-62.
395.
1996

R Gartenhaus; M M Johns; P Wang; K Rai; D Sidransky

Mutator phenotype in a subset of chronic lymphocytic leukemia.
Blood 1996;87(1):38-41.
396.
1996

D Sidransky; M Hollstein

Clinical implications of the p53 gene.
Annual review of medicine 1996;47():285-301.
397.
1995

G I Shapiro; J E Park; C D Edwards; L Mao; A Merlo; D Sidransky; M E Ewen; B J Rollins

Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines.
Cancer research 1995;55(24):6200-9.
398.
1995

M P Rosin; P Cairns; J I Epstein; M P Schoenberg; D Sidransky

Partial allelotype of carcinoma in situ of the human bladder.
Cancer research 1995;55(22):5213-6.
399.
1995

T J Polascik; P Cairns; W Y Chang; M P Schoenberg; D Sidransky

Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma.
Cancer research 1995;55(22):5396-9.
400.
1995

J G Herman; A Merlo; L Mao; R G Lapidus; J P Issa; N E Davidson; D Sidransky; S B Baylin

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.
Cancer research 1995;55(20):4525-30.
401.
1995

D Sidransky

Importance of chromosome 9p loss in human lung cancer.
Journal of the National Cancer Institute 1995;87(16):1201-2.
402.
1995

W Y Chang; P Cairns; M P Schoenberg; T J Polascik; D Sidransky

Novel suppressor loci on chromosome 14q in primary bladder cancer.
Cancer research 1995;55(15):3246-9.
403.
1995

A Bedi; J P Barber; G C Bedi; W S el-Deiry; D Sidransky; M S Vala; A J Akhtar; J Hilton; R J Jones

BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents.
Blood 1995;86(3):1148-58.
404.
1995

L Mao; A Merlo; G Bedi; G I Shapiro; C D Edwards; B J Rollins; D Sidransky

A novel p16INK4A transcript.
Cancer research 1995;55(14):2995-7.
405.
1995

A Merlo; J G Herman; L Mao; D J Lee; E Gabrielson; P C Burger; S B Baylin; D Sidransky

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Nature medicine 1995;1(7):686-92.
406.
1995

D Sidransky

Screening for clonal genetic alterations.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1127-9.
407.
1995

D Sidransky

Molecular genetics of head and neck cancer.
Current opinion in oncology 1995;7(3):229-33.
408.
1995

J A Brennan; J O Boyle; W M Koch; S N Goodman; R H Hruban; Y J Eby; M J Couch; A A Forastiere; D Sidransky

Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck.
The New England journal of medicine 1995;332(11):712-7.
409.
1995

W M Koch; H Patel; J Brennan; J O Boyle; D Sidransky

Squamous cell carcinoma of the head and neck in the elderly.
Archives of otolaryngology--head & neck surgery 1995;121(3):262-5.
410.
1995

C S Rabkin; G Bedi; E Musaba; R Sunkutu; N Mwansa; D Sidransky; R J Biggar

AIDS-related Kaposi's sarcoma is a clonal neoplasm.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(3):257-60.
411.
1995

D Sidransky

Molecular markers in cancer: can we make better predictions?
International journal of cancer. Journal international du cancer 1995;64(1):1-2.
412.
1995

J A Brennan; L Mao; R H Hruban; J O Boyle; Y J Eby; W M Koch; S N Goodman; D Sidransky

Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck.
The New England journal of medicine 1995;332(7):429-35.
413.
1995

P Cairns; K Tokino; Y Eby; D Sidransky

Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas.
Cancer research 1995;55(2):224-7.
414.
1995

M Schoenberg; P Cairns; J D Brooks; F F Marshall; J I Epstein; W B Isaacs; D Sidransky

Frequent loss of chromosome arms 8p and 13q in collecting duct carcinoma (CDC) of the kidney.
Genes, chromosomes & cancer 1995;12(1):76-80.
415.
1995

G C Bedi; W H Westra; H Farzadegan; P M Pitha; D Sidransky

Microsatellite instability in primary neoplasms from HIV + patients.
Nature medicine 1995;1(1):65-8.
416.
1995

D Sidransky

Molecular markers in cancer diagnosis.
Journal of the National Cancer Institute. Monographs 1995;(17):27-9.
417.
1994

J O Boyle; L Mao; J A Brennan; W M Koch; D W Eisele; J R Saunders; D Sidransky

Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas.
American journal of surgery 1994;168(5):429-32.
418.
1994

L Mao; D J Lee; M S Tockman; Y S Erozan; F Askin; D Sidransky

Microsatellite alterations as clonal markers for the detection of human cancer.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9871-5.
419.
1994

J E Blaugrund; M M Johns; Y J Eby; D W Ball; S B Baylin; R H Hruban; D Sidransky

RET proto-oncogene mutations in inherited and sporadic medullary thyroid cancer.
Human molecular genetics 1994;3(10):1895-7.
420.
1994

G H Yoo; H J Xu; J A Brennan; W Westra; R H Hruban; W Koch; W F Benedict; D Sidransky

Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma.
Cancer research 1994;54(17):4603-6.
421.
1994

W M Koch; J O Boyle; L Mao; J Hakim; R H Hruban; D Sidransky

p53 gene mutations as markers of tumor spread in synchronous oral cancers.
Archives of otolaryngology--head & neck surgery 1994;120(9):943-7.
422.
1994

D P Huang; K W Lo; C A van Hasselt; J K Woo; P H Choi; S F Leung; S T Cheung; P Cairns; D Sidransky; J C Lee

A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.
Cancer research 1994;54(15):4003-6.
423.
1994

P Cairns; L Mao; A Merlo; D J Lee; D Schwab; Y Eby; K Tokino; P van der Riet; J E Blaugrund; D Sidransky

Rates of p16 (MTS1) mutations in primary tumors with 9p loss.
Science (New York, N.Y.) 1994;265(5170):415-7.
424.
1994

D Sidransky

Molecular screening--how long can we afford to wait?
Journal of the National Cancer Institute 1994;86(13):955-6.
425.
1994

S Thomas; J Brennan; G Martel; I Frazer; R Montesano; D Sidransky; M Hollstein

Mutations in the conserved regions of p53 are infrequent in betel-associated oral cancers from Papua New Guinea.
Cancer research 1994;54(13):3588-93.
426.
1994

R H Hruban; P van der Riet; Y S Erozan; D Sidransky

Brief report: molecular biology and the early detection of carcinoma of the bladder--the case of Hubert H. Humphrey.
The New England journal of medicine 1994;330(18):1276-8.
427.
1994

A Merlo; E Gabrielson; M Mabry; R Vollmer; S B Baylin; D Sidransky

Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer.
Cancer research 1994;54(9):2322-6.
428.
1994

A Merlo; M Mabry; E Gabrielson; R Vollmer; S B Baylin; D Sidransky

Frequent microsatellite instability in primary small cell lung cancer.
Cancer research 1994;54(8):2098-101.
429.
1994

L Mao; R H Hruban; J O Boyle; M Tockman; D Sidransky

Detection of oncogene mutations in sputum precedes diagnosis of lung cancer.
Cancer research 1994;54(7):1634-7.
430.
1994

L Mao; D Sidransky

Cancer screening based on genetic alterations in human tumors.
Cancer research 1994;54(7 Suppl):1939s-1940s.
431.
1994

H A Erlich; C Gorodezky; R Saiki; D Sidransky; J Sninsky

Molecular biology of cancer, virus and HLA typing.
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición 1994;Suppl():59-61.
432.
1994

P Cairns; K Tokino; Y Eby; D Sidransky

Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction.
Cancer research 1994;54(6):1422-4.
433.
1994

H Nawroz; P van der Riet; R H Hruban; W Koch; J M Ruppert; D Sidransky

Allelotype of head and neck squamous cell carcinoma.
Cancer research 1994;54(5):1152-5.
434.
1994

P van der Riet; H Nawroz; R H Hruban; R Corio; K Tokino; W Koch; D Sidransky

Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.
Cancer research 1994;54(5):1156-8.
435.
1994

L Mao; D Sidransky

Tetranucleotide repeat polymorphism in RAF1.
Human molecular genetics 1994;3(3):521.
436.
1994

A Merlo; E Gabrielson; F Askin; D Sidransky

Frequent loss of chromosome 9 in human primary non-small cell lung cancer.
Cancer research 1994;54(3):640-2.
437.
1994

P van der Riet; D Karp; E Farmer; Q Wei; L Grossman; K Tokino; J M Ruppert; D Sidransky

Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele.
Cancer research 1994;54(1):25-7.
438.
1993

D Sidransky; J Boyle; W Koch

Molecular screening. Prospects for a new approach.
Archives of otolaryngology--head & neck surgery 1993;119(11):1187-90.
439.
1993

J M Ruppert; K Tokino; D Sidransky

Evidence for two bladder cancer suppressor loci on human chromosome 9.
Cancer research 1993;53(21):5093-5.
440.
1993

T Tokino; N Davidson; K Helzlsouer; B Zehnbauer; Y Nakamura; B Vogelstein; D Sidransky

Absence of germline prohibitin mutations in early-onset breast-cancer.
International journal of oncology 1993;3(4):769-72.
441.
1993

J O Boyle; J Hakim; W Koch; P van der Riet; R H Hruban; R A Roa; R Correo; Y J Eby; J M Ruppert; D Sidransky

The incidence of p53 mutations increases with progression of head and neck cancer.
Cancer research 1993;53(19):4477-80.
442.
1993

F S Leach; T Tokino; P Meltzer; M Burrell; J D Oliner; S Smith; D E Hill; D Sidransky; K W Kinzler; B Vogelstein

p53 Mutation and MDM2 amplification in human soft tissue sarcomas.
Cancer research 1993;53(10 Suppl):2231-4.
443.
1993

P Celano; C M Berchtold; M Mabry; M Carroll; D Sidransky; R A Casero; R Lupu

Induction of markers of normal differentiation in human colon carcinoma cells by the v-rasH oncogene.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(4):341-7.
444.
1993

D Sidransky; J Boyle; W Koch; P van der Riet

Oncogene mutations as intermediate markers.
Journal of cellular biochemistry. Supplement 1993;17F():184-7.
445.
1992

D Sidransky; E Messing

Molecular genetics and biochemical mechanisms in bladder cancer. Oncogenes, tumor suppressor genes, and growth factors.
The Urologic clinics of North America 1992;19(4):629-39.
446.
1992

D Sidransky; T Tokino; K Helzlsouer; B Zehnbauer; G Rausch; B Shelton; L Prestigiacomo; B Vogelstein; N Davidson

Inherited p53 gene mutations in breast cancer.
Cancer research 1992;52(10):2984-6.
447.
1992

D Sidransky; T Tokino; S R Hamilton; K W Kinzler; B Levin; P Frost; B Vogelstein

Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.
Science (New York, N.Y.) 1992;256(5053):102-5.
448.
1992

D Sidransky; P Frost; A Von Eschenbach; R Oyasu; A C Preisinger; B Vogelstein

Clonal origin bladder cancer.
The New England journal of medicine 1992;326(11):737-40.
449.
1992

W P Bennett; M C Hollstein; I C Hsu; D Sidransky; D P Lane; B Vogelstein; C C Harris

Mutational spectra and immunohistochemical analyses of p53 in human cancers.
Chest 1992;101(3 Suppl):19S-20S.
450.
1992

D Sidransky; T Mikkelsen; K Schwechheimer; M L Rosenblum; W Cavanee; B Vogelstein

Clonal expansion of p53 mutant cells is associated with brain tumour progression.
Nature 1992;355(6363):846-7.
451.
1991

M B Kastan; O Onyekwere; D Sidransky; B Vogelstein; R W Craig

Participation of p53 protein in the cellular response to DNA damage.
Cancer research 1991;51(23 Pt 1):6304-11.
452.
1991

R L Saylors; D Sidransky; H S Friedman; S H Bigner; D D Bigner; B Vogelstein; G M Brodeur

Infrequent p53 gene mutations in medulloblastomas.
Cancer research 1991;51(17):4721-3.
453.
1991

M Hollstein; D Sidransky; B Vogelstein; C C Harris

p53 mutations in human cancers.
Science (New York, N.Y.) 1991;253(5015):49-53.
454.
1991

D Sidransky; A Von Eschenbach; Y C Tsai; P Jones; I Summerhayes; F Marshall; M Paul; P Green; S R Hamilton; P Frost

Identification of p53 gene mutations in bladder cancers and urine samples.
Science (New York, N.Y.) 1991;252(5006):706-9.

David Sidransky The Johns Hopkins University, School of Medicine

David Sidransky

454 Publications

David Sidransky
The Johns Hopkins University, School of Medicine