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Peter Barker

Publication Detail

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Diffusion-negative stroke: a report of two cases.

P Y Wang; P B Barker; R J Wityk; A M Uluğ; P C van Zijl; N J Beauchamp (Profiled Authors: Peter Van Zijl; Robert Wityk; Peter Barker)

Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
AJNR. American journal of neuroradiology 1999;20(10):1876-80.

Abstract

Diffusion-weighted MR imaging is generally thought to be highly sensitive for the diagnosis of acute stroke. We report two cases of hyperacute stroke with absence of changes on diffusion-weighted images within 4 hours of symptom onset. Follow-up studies, performed 4 days later, showed infarction in regions compatible with the clinical presentation and (in one case) with the initial perfusion deficit. These cases indicate that normal findings on diffusion-weighted images in patients with suspected cerebral ischemia do not rule out impending infarction.

Scientific Context

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