The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Severe pulmonary hypertension after the discovery of the familial primary pulmonary hypertension gene.
R M Tuder; M E Yeager; M Geraci; H A Golpon; N F Voelkel (Profiled Author: Rubin Tuder)
Dept of Pathology, University of Colorado Health Sciences Center, USA.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(6):1065-9.
The recent discoveries of the familial primary pulmonary hypertension gene and somatic mutations in key cell growth and cell death regulatory genes in primary pulmonary hypertension have added a new dimension to severe pulmonary hypertension research. These findings have already impacted on how the disease is viewed, and ultimately, how severe pulmonary hypertension is diagnosed and treated. However, this new information raises several fundamental questions related to the role of bone morphogenetic protein receptor signalling in the control of lung vascular cell function. Furthermore, additional genes and gene products may also be involved in the pathogenesis of the disease. The way severe pulmonary hypertension is viewed and studied is on the verge of shifting from a vasoconstrictive to a cell growth paradigm.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
M E Yeager; G R Halley; H A Golpon; N F Voelkel; R M TuderCirculation research 2001;88(1):E2-E11.
Michael E Yeager; Heiko A Golpon; Norbert F Voelkel; Rubin M TuderChest 2002;121(3 Suppl):61S.
Carlyne D Cool; Pradeep R Rai; Michael E Yeager; Daniel Hernandez-Saavedra; Amanda E Serls; Todd M Bull; Mark W Geraci; Kevin K Brown; John M Routes; Rubin M Tuder; et al.The New England journal of medicine 2003;349(12):1113-22.
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