The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Detection of intracranial hemorrhage: comparison between gradient-echo images and b(0) images obtained from diffusion-weighted echo-planar sequences.
D D Lin; C G Filippi; A B Steever; R D Zimmerman (Profiled Author: Doris Lin)
Department of Radiology, Division of Neuroradiology, New York Presbyterian Hospital, 525 E. 68th St., New York, NY 10021, USA.
AJNR. American journal of neuroradiology 2001;22(7):1275-81.
BACKGROUND AND PURPOSE: Diffusion-weighted MR imaging (DWI) is commonly used as the initial and sole imaging examination for the detection of acute cerebral infarction, yet it remains controversial whether MR can detect hyperacute (<24 h) hemorrhage. Hemorrhage is best detected with gradient-echo (GRE) T2*-weighted sequences, because of their magnetic susceptibility effects. DWI uses a spin-echo echo-planar technique (EPI) that is more sensitive than spin-echo T2-weighted imaging to susceptibility effects. Our aim was to determine whether the b(0) image from the DWI-EPI sequence is as sensitive as GRE in detecting hemorrhagic lesions on imaging studies performed to identify acute infarction or hemorrhage. METHODS: All MR studies performed for clinically suspected or radiographically confirmed acute infarction or hemorrhage from 2/1/98 to 8/15/99 were retrospectively interpreted by one neuroradiologist in a blinded fashion. The sensitivity of hemorrhage detection, conspicuity of lesions, and diagnostic certainty were compared between the b(0) EPI and GRE sequences. RESULTS: We found 101 acute infarcts, of which 13 were hemorrhagic, as evidenced by the presence of hypointensity within the infarction on the GRE sequence. This finding served as the reference standard for detection of hemorrhage. Hemorrhage was diagnosed with confidence in only seven cases (54%) on b(0) images; 22 acute hematomas were hypointense on GRE images whereas 19 were hypointense on b(0) images (86%); 17 chronic hematomas were depicted on GRE images and 12 on b(0) scans (63%). Punctate hemorrhages and linear cortical staining were detected on 37 GRE studies but on only four b(0) studies. Hemorrhage was always more conspicuous on the GRE sequences. CONCLUSION: b(0) images from a DWI sequence failed to detect minimally hemorrhagic infarctions and small chronic hemorrhages associated with microangiopathy. GRE scans were more sensitive than b(0) images in the detection of these hemorrhages and should be included in emergency brain MR studies for acute infarction, especially when thrombolytic therapy is contemplated.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
P Y Wang; P B Barker; R J Wityk; A M Uluğ; P C van Zijl; N J BeauchampAJNR. American journal of neuroradiology 1999;20(10):1876-80.
B C PEVEHOUSE; B A BROWNCalifornia medicine 1962;97():268-72.
Ronald D Cohn; Erik Eklund; Amanda L Bergner; James F Casella; S Lee Woods; Janyne Althaus; Karin J Blakemore; Harold E Fox; Julie E Hoover-Fong; Ada Hamosh; et al.Pediatrics 2006;118(2):e514-21.
Appears in this Publication
Author of this Publication