The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Higher blood pressure in middle-aged American adults with less education-role of multiple dietary factors: the INTERMAP study.
J Stamler; P Elliott; L Appel; Q Chan; M Buzzard; B Dennis; A R Dyer; P Elmer; P Greenland; D Jones; et al. (Profiled Author: Lawrence Appel)
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. email@example.com
Journal of human hypertension 2003;17(9):655-775.
Extensive evidence exists that an inverse relation between education and blood pressure prevails in many adult populations, but little research has been carried out on reasons for this finding. A prior goal of the INTERMAP Study was to investigate this phenomenon further, and to assess the role of dietary factors in accounting for it. Of the 4680 men and women aged 40-59 years, from 17 diverse population samples in Japan, People's Republic of China, UK, and USA, a strong significant inverse education-BP relation was manifest particularly for the 2195 USA participants, independent of ethnicity. With participants stratified by years of education, and assessment of 100+ dietary variables from four 24-h dietary recalls and two 24-h urine collections/person, graded relationships were found between education and intake of many macro- and micronutrients, electrolytes, fibre, and body mass index (BMI). In multiple linear regression analyses with systolic BP (SBP) and diastolic BP (DBP) of individuals the dependent variables (controlled for ethnicity, other possible nondietary confounders), BMI markedly reduced size of education-BP relations, more so for women than for men. Several nutrients considered singly further decreased size of this association by > or =10%: urinary 24-h Na and K excretion, Keys dietary lipid score, vegetable protein, fibre, vitamins C and B6, thiamin, riboflavin, folate, calcium, magnesium, and iron. Combinations of these dietary variables and BMI attenuated the education-SBP inverse coefficient by 54-58%, and the education-DBP inverse coefficient by 59-67%, with over half these effects attributable to specific nutrients (independent of BMI). As a result, the inverse education-BP coefficients ceased to be statistically significant. Multiple specific dietary factors together with body mass largely account for the more adverse BP levels of less educated than more educated Americans. Special efforts to improve eating patterns of less educated strata can contribute importantly to overcoming this and related health disparities in the population.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Laura C Plantinga; Edgar R Miller; Lesley A Stevens; Rajiv Saran; Kassandra Messer; Nicole Flowers; Linda Geiss; Neil R Powe;Hypertension 2009;54(1):47-56.
Pao-Hwa Lin; Lawrence J Appel; Kristine Funk; Shirley Craddick; Chuhe Chen; Patricia Elmer; Mary Ann McBurnie; Catherine ChampagneJournal of the American Dietetic Association 2007;107(9):1541-51.
S Kumanyika; G S Tell; L Fried; J K Martel; V M ChinchilliJournal of the American Dietetic Association 1996;96(2):137-44.
Appears in this Publication
Author of this Publication