The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
p63-specific activation of the BPAG-1e promoter.
Motonobu Osada; Yuichi Nagakawa; Hannah Lui Park; Keishi Yamashita; Guojun Wu; Myoung Sook Kim; Alexey Fomenkov; Barry Trink; David Sidransky (Profiled Authors: David Sidransky; Myoung Kim; Barry Trink)
Department of Otolaryngology, Division of Head and Neck Cancer Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. email@example.com
The Journal of investigative dermatology 2005;125(1):52-60.
p63, a member of the p53 superfamily, is an essential cell fate determinant for stratified epithelium. Deficiency of p63 leads to lack of differentiated epithelium from the skin and the presence of trace undifferentiated cells left in the dermis. We found that transcriptionally active isoforms of p63, TAp63beta and TAp63gamma, activated the skin-specific promoter of bullous pemphigoid antigen 1 (BPAG-1). The p63-response element was localized between bases -177 and -153 upstream of exon 1 in the BPAG-1e promoter, whereas regions surrounding the response element suppressed transcriptional responses to p53 and TAp73beta, resulting in p63-specific activation of the promoter. This represents a novel molecular mechanism by which target gene induction by p63 is distinguished from induction by other p53 family members.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Motonobu Osada; Hannah Lui Park; Yuichi Nagakawa; Keishi Yamashita; Alexey Fomenkov; Myoung Sook Kim; Guojun Wu; Shuji Nomoto; Barry Trink; David SidranskyMolecular and cellular biology 2005;25(14):6077-89.
Alexey Fomenkov; Yi-Ping Huang; Ozlem Topaloglu; Anna Brechman; Motonobo Osada; Tanya Fomenkova; Eugene Yuriditsky; Barry Trink; David Sidransky; Edward RatovitskiThe Journal of biological chemistry 2003;278(26):23906-14.
Guojun Wu; Motonobu Osada; Zhongmin Guo; Alexey Fomenkov; Shahnaz Begum; Ming Zhao; Sunil Upadhyay; Mingzhao Xing; Feng Wu; Chulso Moon; et al.Cancer research 2005;65(3):758-66.
Appears in this Publication
Author of this Publication