The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
En bloc resection of primary sacral tumors: classification of surgical approaches and outcome.
Daryl R Fourney; Laurence D Rhines; Stephen J Hentschel; John M Skibber; Jean-Paul Wolinsky; Kristin L Weber; Dima Suki; Gary L Gallia; Ira Garonzik; Ziya L Gokaslan (Profiled Authors: Gary Gallia; Ziya Gokaslan; Jean-Paul Wolinsky; Kristin Weber)
Division of Neurosurgery, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Journal of neurosurgery. Spine 2005;3(2):111-22.
OBJECT: En bloc resection with adequate margins is associated with the highest probability of long-term tumor control or cure in most cases of primary sacral malignancies. The authors present their experience with a systematic approach to these lesions. They provide a novel classification of surgical techniques based on the level of nerve root sacrifice and evaluate the functional and oncological outcomes. METHODS: Seventy-eight consecutive patients underwent 94 resections of sacral neoplasms at The University of Texas M. D. Anderson Cancer Center in Houston between August 1993 and June 2002. The records of 29 consecutive patients who underwent en bloc resection of primary sacral tumors were retrospectively reviewed. The median follow-up period was 55 months (range 1-103 months). Chordoma was the most frequent tumor type (16 cases). Midline sacral amputation was performed in 25 patients (eight low, four middle, seven high, and five total sacrectomies; one hemicorporectomy). Lateral sacrectomy was undertaken in four patients (two unilateral excisions of the sacroiliac joint and two hemisacrectomies). The surgical margins were wide in 19 cases, marginal in nine, and contaminated in one. The type of sacrectomy correlated with characteristic outcomes with respect to bladder, bowel, and ambulatory functions. Duration of hospital stay was related to the extent of sacrectomy (p = 0.003, Wilcoxon signed-rank test). The median Kaplan-Meier disease-free survival for patients with chordoma was 68 months (95% confidence interval 46-90 months). CONCLUSIONS: Classification of en bloc sacral resection techniques by the level of nerve root transection is useful in predicting postoperative function and the potential for morbidity. Adequate surgical margins should not be compromised to preserve function when they are necessary to affect tumor control.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Ganesh Rao; George J Chang; Ian Suk; Ziya Gokaslan; Laurence D RhinesNeurosurgery 2010;66(3 Suppl Operative):41-4.
Daniel M Sciubba; John H Chi; Laurence D Rhines; Ziya L GokaslanNeurosurgery clinics of North America 2008;19(1):5-15.
Gary L Gallia; Daniel M Sciubba; Ali Bydon; Ian Suk; Jean-Paul Wolinsky; Ziya L Gokaslan; Timothy F WithamJournal of neurosurgery. Spine 2007;7(1):103-11.
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