Kenichi Oishi

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Towards a statistical atlas of cardiac fiber structure.

Jean-Marc Peyrat; Maxime Sermesant; Xavier Pennec; Hervé Delingette; Chenyang Xu; Elliot McVeigh; Nicholas Ayache (Profiled Author: Elliot Mcveigh)

INRIA, Asclepios Research Project, Sophia Antipolis, France. jean-marc.peyrat@sophia.inria.fr
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 2006;9(Pt 1):297-304.

We propose here a framework to build a statistical atlas of diffusion tensors of canine hearts. The anatomical images of seven hearts are first non-rigidly registered in the same reference frame and their associated diffusion tensors are then transformed with a method that preserves the cardiac laminar sheets. In this referential frame, the mean tensor and its covariance matrix are computed based on the Log-Euclidean framework. With this method, we can produce a smooth mean tensor field that is suited for fiber tracking algorithms or the electromechanical modeling of the heart. In addition, by examining the covariance matrix at each voxel it is possible to assess the variability of the cardiac fiber directions and of the orientations of laminar sheets. The results show a strong coherence of the diffusion tensors and the fiber orientations among a population of seven normal canine hearts.

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