The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Fluorinated lipid constructs permit facile passage of molecular cargo into living cells.
Laila Dafik; Venkateshwarlu Kalsani; Anthony Kar Lun Leung; Krishna Kumar (Profiled Author: Anthony Leung)
Department of Chemistry, Tufts University, Medford, Massachusetts 02155, USA.
Journal of the American Chemical Society 2009;131(34):12091-3.
Fluorinated lipids get rapidly internalized into living cells and are also displayed on the cell surface. The uptake of lipids is energy dependent and is likely via the clathrin-mediated endocytic pathway. Fluorinated lipids are 3-5-fold more efficient in acting as molecular transporters of noncovalently bound proteins than their hydrocarbon counterparts. These materials could serve as efficient molecular transporters for molecules that function in the cytoplasm such as short interfering RNAs (siRNAs).
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