The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients.
Andrew Campbell; Caterina P Minniti; Mehdi Nouraie; Manuel Arteta; Sohail Rana; Onyinye Onyekwere; Craig Sable; Gregory Ensing; Niti Dham; Lori Luchtman-Jones; et al. (Profiled Author: Gregory Kato)
University of Michigan, Ann Arbor, MI, USA.
British journal of haematology 2009;147(3):352-9.
Low steady state haemoglobin oxygen saturation in patients with sickle cell anaemia has been associated with the degree of anaemia and haemolysis. How much pulmonary dysfunction contributes to low saturation is not clear. In a prospective study of children and adolescents with sickle cell disease aged 3-20 years at steady state and matched controls, 52% of 391 patients versus 24% of 63 controls had steady state oxygen saturation <99% (P < 0.0001), 9% of patients versus no controls had saturation <95% (P = 0.008) and 8% of patients versus no controls had exercise-induced reduction in saturation > or =3%. Decreasing haemoglobin concentration (P < or = 0.001) and increasing haemolysis (P < or = 0.003) but not pulmonary function tests were independent predictors of both lower steady-state saturation and exercise-induced reduction in saturation. Neither history of stroke nor history of acute chest syndrome was significantly associated with lower steady-state oxygen saturation or exercise-induced reduction in saturation. Tricuspid regurgitation velocity was higher in patients with lower steady state haemoglobin oxygen saturation (P = 0.003) and with greater decline in oxygen saturation during the six-minute walk (P = 0.022). In conclusion, lower haemoglobin oxygen saturation is independently associated with increasing degrees of anaemia and haemolysis but not pulmonary function abnormalities among children and adolescents with sickle cell disease.
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Caterina P Minniti; Craig Sable; Andrew Campbell; Sohail Rana; Gregory Ensing; Niti Dham; Onyinye Onyekwere; Mehdi Nouraie; Gregory J Kato; Mark T Gladwin; et al.Haematologica 2009;94(3):340-7.
Enrico M Novelli; Gregory J Kato; Margaret V Ragni; Yingze Zhang; Mariana E Hildesheim; Mehdi Nouraie; Suchitra Barge; Michael P Meyer; Andrea Cortese Hassett; Victor R Gordeuk; et al.American journal of hematology 2012;87(3):326-30.
Xiaomei Niu; Mehdi Nouraie; Andrew Campbell; Sohail Rana; Caterina P Minniti; Craig Sable; Deepika Darbari; Niti Dham; N Scott Reading; Josef T Prchal; et al.PloS one 2009;4(11):e7956.
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