The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Perioperative mortality and long-term survival following live kidney donation.
Dorry L Segev; Abimereki D Muzaale; Brian S Caffo; Shruti H Mehta; Andrew L Singer; Sarah E Taranto; Maureen A McBride; Robert A Montgomery (Profiled Authors: Brian Caffo; Robert Montgomery; Dorry Segev; Andrew Singer)
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. email@example.com
JAMA : the journal of the American Medical Association 2010;303(10):959-66.
CONTEXT: More than 6000 healthy US individuals every year undergo nephrectomy for the purposes of live donation; however, safety remains in question because longitudinal outcome studies have occurred at single centers with limited generalizability. OBJECTIVES: To study national trends in live kidney donor selection and outcome, to estimate short-term operative risk in various strata of live donors, and to compare long-term death rates with a matched cohort of nondonors who are as similar to the donor cohort as possible and as free as possible from contraindications to live donation. DESIGN, SETTING, AND PARTICIPANTS: Live donors were drawn from a mandated national registry of 80 347 live kidney donors in the United States between April 1, 1994, and March 31, 2009. Median (interquartile range) follow-up was 6.3 (3.2-9.8) years. A matched cohort was drawn from 9364 participants of the third National Health and Nutrition Examination Survey (NHANES III) after excluding those with contraindications to kidney donation. MAIN OUTCOME MEASURES: Surgical mortality and long-term survival. RESULTS: There were 25 deaths within 90 days of live kidney donation during the study period. Surgical mortality from live kidney donation was 3.1 per 10,000 donors (95% confidence interval [CI], 2.0-4.6) and did not change during the last 15 years despite differences in practice and selection. Surgical mortality was higher in men than in women (5.1 vs 1.7 per 10,000 donors; risk ratio [RR], 3.0; 95% CI, 1.3-6.9; P = .007), in black vs white and Hispanic individuals (7.6 vs 2.6 and 2.0 per 10,000 donors; RR, 3.1; 95% CI, 1.3-7.1; P = .01), and in donors with hypertension vs without hypertension (36.7 vs 1.3 per 10,000 donors; RR, 27.4; 95% CI, 5.0-149.5; P < .001). However, long-term risk of death was no higher for live donors than for age- and comorbidity-matched NHANES III participants for all patients and also stratified by age, sex, and race. CONCLUSION: Among a cohort of live kidney donors compared with a healthy matched cohort, the mortality rate was not significantly increased after a median of 6.3 years.
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L Ebony Boulware; Lloyd E Ratner; Julie Ann Sosa; Alexander H Tu; Satish Nagula; Christopher E Simpkins; Raegan W Durant; Neil R PoweAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2002;2(2):186-93.
Abimereki D Muzaale; Nabil N Dagher; Robert A Montgomery; Sarah E Taranto; Maureen A McBride; Dorry L SegevGastroenterology 2012;142(2):273-80.
M E Allaf; A Singer; W Shen; I Green; K Womer; D L Segev; R A MontgomeryAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2010;10(6):1473-7.
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