The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
The relationship between patients' serum glucose levels and metabolically active brown adipose tissue detected by PET/CT.
Heather A Jacene; Christian C Cohade; Zhe Zhang; Richard L Wahl (Profiled Author: Heather Jacene)
Russell H. Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(6):1278-83.
PURPOSE: To compare blood glucose levels in patients with or without "detectable" brown adipose tissue (BAT) using 2-deoxy-2-[(18)F]fluoro-D-glucose positron emission tomography/computed tomography (FDG PET/CT). PROCEDURES: Nine hundred eight patients had PET/CT scans and were previously identified as having, or not having, FDG uptake in BAT. The original database was retrospectively reviewed for blood glucose level and body mass index (BMI) at the time of imaging. Blood glucose levels were compared between patients with or without FDG uptake in BAT, adjusting for age, sex, and BMI. RESULTS: Fifty-six patients (6.2%) had FDG uptake in BAT. In the univariate analysis, patients without FDG uptake in BAT had a higher risk of glucose ≥100 mg/dL (odds ratio 3.4, 95% CI = 1.6-7.3; P = 0.0007). After adjustment for age, sex, BMI, and significant interaction of sex and BMI, patients without BAT tended to have a higher risk of glucose ≥100 mg/dL, although not statistically significant (odds ratio = 1.6, 95% CI = 0.7-3.6; P = 0.268). CONCLUSIONS: Although causal relationships are not specified, the data suggest that BAT uptake, glucose levels, BMI, sex, and age are inter-related and the possibility that presence of "detectable" BAT is protective against diabetes and obesity. FDG PET/CT may be a vital tool for further investigations of diabetes and obesity.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Heather A Jacene; Richard L WahlThe New England journal of medicine 2009;361(4):417-8; author reply 419-20.
Sibyll Goetze; William C Lavely; Harvey A Ziessman; Richard L WahlJournal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(5):752-6.
R P Stolk; P Suriyawongpaisal; W Aekplakorn; M Woodward; B Neal;Diabetologia 2005;48(4):657-60.
Appears in this Publication
Author of this Publication