The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Long-term implications of emergency versus elective proximal aortic surgery in patients with Marfan syndrome in the Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions Consortium Registry.
Howard K Song; Mark Kindem; Joseph E Bavaria; Harry C Dietz; Dianna M Milewicz; Richard B Devereux; Kim A Eagle; Cheryl L Maslen; Barbara L Kroner; Reed E Pyeritz; et al. (Profiled Authors: Kathryn Holmes; William Ravekes; Harry Dietz)
Division of Cardiothoracic Surgery, Oregon Health & Science University, Portland, OR 97239, USA. firstname.lastname@example.org
The Journal of thoracic and cardiovascular surgery 2012;143(2):282-6.
OBJECTIVE: Patients with Marfan syndrome with aortic root aneurysms undergo elective aortic root replacement to avoid the life-threatening outcomes of aortic dissection and emergency repair. The long-term implications of failed aortic surveillance leading to acute dissection and emergency repair are poorly defined. We compared the long-term clinical courses of patients with Marfan syndrome who survive emergency versus elective proximal aortic surgery. METHODS: The Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions Registry is a National Institutes of Health-funded multicenter database and biorepository that enrolls patients with genetically triggered thoracic aortic aneurysms. Of the 635 patients with Marfan syndrome enrolled as of March 2011, 194 had undergone proximal aortic replacement. Patients were grouped according to emergency (n = 47) or elective (n = 147) status at the time of surgery. RESULTS: Patients in the emergency group were more likely to have incomplete proximal aortic resection; 83% of emergency procedures included aortic root replacement, compared with 95% of elective procedures. At long-term follow-up (mean, >6 years), the emergency group had a higher incidence of chronic dissection of the distal aorta and significantly larger diameters in distal aortic segments than elective patients. Patients in the emergency group had undergone more operations (1.31 vs 1.11 procedures/patient; P = .01) and had lower activity scores on a health-related quality of life survey. CONCLUSIONS: For patients with Marfan syndrome, failed aortic surveillance and consequent emergency dissection repair have important long-term implications with regard to the status of the distal aorta, need for multiple procedures, and quality of life. These findings emphasize the importance of aortic surveillance and timely elective aortic root aneurysm repair for patients with Marfan syndrome.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Howard K Song; Joseph E Bavaria; Mark W Kindem; Kathryn W Holmes; Dianna M Milewicz; Cheryl L Maslen; Reed E Pyeritz; Craig T Basson; Kim Eagle; H Eser Tolunay; et al.The Annals of thoracic surgery 2009;88(3):781-7; discussion 787-8.
Nishant D Patel; Eric S Weiss; Diane E Alejo; Lois U Nwakanma; Jason A Williams; Harry C Dietz; Philip J Spevak; Vincent L Gott; Luca A Vricella; Duke E CameronThe Annals of thoracic surgery 2008;85(6):2003-10; discussion 2010-1.
Daniel Y Sze; Maurice A A J van den Bosch; Michael D Dake; D Craig Miller; Lawrence V Hofmann; Robin Varghese; S Chris Malaisrie; Pieter J A van der Starre; Jarrett Rosenberg; R Scott MitchellCirculation. Cardiovascular interventions 2009;2(2):105-12.
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