The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Experimental intra-abdominal abscesses in rats: quantitative bacteriology of infected animals.
A B Onderdonk; W M Weinstein; N M Sullivan; J G Bartlett; S L Gorbach (Profiled Author: John Bartlett)
Infection and immunity 1974;10(6):1256-9.Abstract
An animal model simulating intra-abdominal sepsis was produced by implanting large bowel contents into the pelvic region of rats. Bacteriological analysis of infected sites showed quantitative differences according to the stage of disease. During the initial, often lethal, peritonitis stage, Escherichia coli (mean concentration, 10(6)/ml), enterococci (10(5)) and Bacterioides fragilis (10(6)) were always present. Blood cultures obtained during this phase were uniformly positive, with E. coli being the principal isolate. Animals that survived this early acute peritonitis stage developed indolent intra-abdominal abscesses. The major isolates in abscess contents were B. fragilis (10(8.7)) and Fusobacterium (10(8.6)); E. coli (10(7.8)) and enterococci (10(5.7)) were also present but in lesser concentrations. Rank order analysis of these four species in peritoneal exudates and abscess pus showed that the two aerobes outranked the two anaerobes during the early stage of the disease, whereas the reverse was true in abscesses. These experiments also illustrated that a major simplification of the original fecal inoculum occurred, even though the subsequent infection remained bacteriologically complex.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
W M Weinstein; A B Onderdonk; J G Bartlett; S L GorbachInfection and immunity 1974;10(6):1250-5.
J G Bartlett; S L Gorbach; S M FinegoldThe American journal of medicine 1974;56(2):202-7.
J G Bartlett; A B Onderdonk; T Louie; D L Kasper; S L GorbachArchives of surgery (Chicago, Ill. : 1960) 1978;113(7):853-7.
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