The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Relationship between perineural tumor invasion on needle biopsy and radical prostatectomy capsular penetration in clinical stage B adenocarcinoma of the prostate.
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
The American journal of surgical pathology 1993;17(4):336-41.
We studied 302 needle biopsies for perineural invasion for sensitivity and specificity in predicting capsular penetration in subsequent radical prostatectomies. Perineural invasion was seen in 20% of needle biopsies, with a sensitivity of 27% and a specificity of 96% in predicting capsular penetration. By including tumor with a Gleason sum of 7 or greater or perineural invasion on needle biopsy as being predictive, sensitivity increased to 36% with a specificity of 94%. By restricting perineural invasion to cases with more than one nerve involved or a nerve involvement of a diameter 0.1 mm or greater, specificity increased to 97% and 99%, respectively, with sensitivity falling to 15% and 9%, respectively. Measuring perineural invasion on needle biopsy helps to identify capsular penetration and may help in planning nerve-sparing radical prostatectomy in the decision of whether to sacrifice part or all of the neurovascular bundle on the side of the biopsy.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
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