The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.
Surveillance of depleted uranium exposed Gulf War veterans: health effects observed in an enlarged "friendly fire" cohort.
M A McDiarmid; K Squibb; S Engelhardt; M Oliver; P Gucer; P D Wilson; R Kane; M Kabat; B Kaup; L Anderson; et al. (Profiled Authors: Patricia W Gucer; Melissa McDiarmid; Katherine S Squibb; Bruce Kaup; Lawrence A Brown)
Department of Medicine, University of Maryland School of Medicine, 405 W. Redwood Street, Baltimore, MD 21201, USA. firstname.lastname@example.org
Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine 2001;43(12):991-1000.
To determine clinical health effects in a small group of US Gulf War veterans (n = 50) who were victims of depleted uranium (DU) "friendly fire," we performed periodic medical surveillance examinations. We obtained urine uranium determinations, clinical laboratory values, reproductive health measures, neurocognitive assessments, and genotoxicity measures. DU-exposed Gulf War veterans with retained metal shrapnel fragments were excreting elevated levels of urine uranium 8 years after their first exposure (range, 0.018 to 39.1 micrograms/g creatinine for DU-exposed Gulf War veterans with retained fragments vs 0.002 to 0.231 microgram/g creatinine in DU exposed but without fragments). The persistence of the elevated urine uranium suggests ongoing mobilization from the DU fragments and results in chronic systemic exposure. Clinical laboratory outcomes, including renal functioning, were essentially normal. Neurocognitive measures showing subtle differences between high and low uranium exposure groups, seen previously, have since diminished. Sister chromatid exchange frequency, a measure of mutation in peripheral lymphocytes, was related to urine uranium level (6.35 sister chromatid exchanges/cell in the high uranium exposure group vs 5.52 sister chromatid exchanges/cell in the low uranium exposure group; P = 0.03). Observed health effects were related to subtle but biologically plausible perturbations in central nervous system function and a general measure of mutagen exposure. The findings related to uranium's chemical rather than radiologic toxicity. Observations in this group of veterans prompt speculation about the health effects of DU in other exposure scenarios.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
M A McDiarmid; J P Keogh; F J Hooper; K McPhaul; K Squibb; R Kane; R DiPino; M Kabat; B Kaup; L Anderson; et al.Environmental research 2000;82(2):168-80.
Katherine S Squibb; Melissa A McDiarmidPhilosophical transactions of the Royal Society of London. Series B, Biological sciences 2006;361(1468):639-48.
M A McDiarmid; S M Engelhardt; M OliverHealth physics 2001;80(3):270-3.
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