Publication Detail

The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.

Evolution of innate and adaptive immunity: can we draw a line?

Martin F Flajnik; Louis Du Pasquier (Profiled Author: Martin F Flajnik)

Department of Microbiology and Immunology, University of Maryland at Baltimore School of Medicine, Baltimore, MD 21201-1559, USA. MFlajnik@som.umaryland.edu
Trends in immunology 2004;25(12):640-4.

Several recent findings in the field of comparative immunology have reinforced the importance of examining the molecular and functional features of immune systems in a variety of organisms. Particularly exciting are the discoveries of a new gene rearrangement mechanism in lampreys and a somatic diversification of mollusk immune genes. These immune features being found in animals previously believed only to have innate immunity, as well as the flood of information on immune genes, molecules and mechanisms in many different creatures, have prompted us to revisit the artificial dichotomy between adaptive and innate immune systems. Although we draw no startling conclusions, we hope to encourage different thought patterns when viewing immune systems.

3 Originating Grant

• 1.

  FLAJNIK, MARTIN F.

  Evolution of Adaptive Immunity

  11 February 1991 - 29 February 2012

  NATIONAL CENTER FOR RESEARCH RESOURCES

• 2.

  Flajnik, Martin F

  Ontogeny and Phylogeny of the MHC

  1 April 1989 - 30 April 2009

  NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

• 3.

  FLAJNIK, MARTIN F

  ONTOGENY AND PHYLOGENY OF THE MHC

  1 April 1989 - 31 March 1994

  NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Scientific Context

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