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Publication Detail

The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.



The use of vaccines in adult patients with renal disease.

Mara Dinits-Pensy; Graeme N Forrest; Alan S Cross; Michael K Hise (Profiled Authors: Alan S Cross; Michael K Hise)

Department of Medicine, Center for Vaccine Development, University of Maryland Medical Center, Baltimore, MD, USA. mdinits@medicine.umaryland.edu
American journal of kidney diseases : the official journal of the National Kidney Foundation 2005;46(6):997-1011.

Abstract

In patients with renal disease, infection remains among the most common causes of morbidity and mortality. Alterations in the function of the immune system, as well as unique exposures of this patient population, account for the increased risk. Vaccination is an invaluable tool in preventing many infectious diseases. Unfortunately, responsiveness to vaccination in patients with renal disease can be diminished. In the present review, we examine the available evidence on the use of vaccinations in adult patients at different stages of chronic kidney disease. We address efficacy, clinical outcomes, and potential costs of individual vaccinations and provide our recommendations based on the literature reviewed. We also identify areas in which additional research is needed.

Scientific Context

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