Kazimierz Nowaczyk

Publication Detail

The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.

Plasmon-controlled fluorescence: a new paradigm in fluorescence spectroscopy.

Joseph R Lakowicz; Krishanu Ray; Mustafa Chowdhury; Henryk Szmacinski; Yi Fu; Jian Zhang; Kazimierz Nowaczyk (Profiled Authors: Yi Fu; Joseph R Lakowicz; Kazimierz Nowaczyk; Krishanu Ray; Henryk Szmacinski; Jian Zhang)

University of Maryland School of Medicine, Center for Fluorescence Spectroscopy, Department of Biochemistry and Molecular Biology, 725 W. Lombard St., Baltimore, MD 21201, USA.
The Analyst 2008;133(10):1308-46.

Fluorescence spectroscopy is widely used in biological research. Until recently, essentially all fluorescence experiments were performed using optical energy which has radiated to the far-field. By far-field we mean at least several wavelengths from the fluorophore, but propagating far-field radiation is usually detected at larger macroscopic distances from the sample. In recent years there has been a growing interest in the interactions of fluorophores with metallic surfaces or particles. Near-field interactions are those occurring within a wavelength distance of an excited fluorophore. The spectral properties of fluorophores can be dramatically altered by near-field interactions with the electron clouds present in metals. These interactions modify the emission in ways not seen in classical fluorescence experiments. In this review we provide an intuitive description of the complex physics of plasmons and near-field interactions. Additionally, we summarize the recent work on metal-fluorophore interactions and suggest how these effects will result in new classes of experimental procedures, novel probes, bioassays and devices.

3 Originating Grant

• 1.

  LAKOWICZ, JOSEPH R.

  Plasmon-Controlled Fluorescence and Cardiac Markers

  1 June 2006 - 31 July 2016

  NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING

• 2.

  LAKOWICZ, JOSEPH R.

  Metallic Surfaces and Particles in DNA Analysis

  27 June 2003 - 30 June 2013

  NATIONAL HUMAN GENOME RESEARCH INSTITUTE

• 3.

  Lakowicz, Joseph R

  Metal-Enhanced Fluorescence Sensing

  30 September 2002 - 31 August 2007

  NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING

Scientific Context

This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts and related grants with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.