Publication Detail

The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in PubMed. This abstract is what is used to create the fingerprint of the publication. If any grants are referenced by the publication, they will be listed here as well.

A simple filter-based approach to surface enhanced Raman spectroscopy for trace chemical detection.

Wei W Yu; Ian M White (Profiled Author: Ian White)

Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA.
The Analyst 2012;137(5):1168-73.

We demonstrate an extremely simple and practical surface enhanced Raman spectroscopy (SERS) technique for trace chemical detection. Filter membranes first trap silver nanoparticles to form a SERS-active substrate and then concentrate analytes from a mL-scale sample into a μL-scale detection volume. We demonstrate a significant improvement in detection limit as compared to colloidal SERS for the pesticide malathion and the food contaminant melamine. The measured SERS intensity exhibits low variation relative to traditional SERS techniques, and the data can be closely fit with a Langmuir isotherm. Thus, due to the simple procedure, the low-cost of the substrates, the quantitative results, and the performance improvement due to analyte concentration, our technique enables SERS to be practical for a broad range of analytical applications, including field-based detection of toxins in large-volume samples.

1 Originating Grant

• 1.

  WHITE, IAN M

  Highly Sensitive Biosensor Platform Using Optical Microring Resonators

  18 September 2006 - 31 August 2011

  NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING

Scientific Context

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