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J Marc Simard

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Systemic arterial hypertension in head trauma.

J M Simard; M Bellefleur (Profiled Authors: J Marc Simard; Monique Bellefleur)

Department of Surgery, University of Texas Medical Branch, Galveston 77550.
The American journal of cardiology 1989;63(6):32C-35C.

Abstract

The importance of maintaining adequate cerebral perfusion pressure to prevent cerebral ischemia is a well accepted concept in the management of patients with head injury. The potentially deleterious effects of too great a perfusion pressure, however, are generally less well appreciated. The occurrence of a hyperadrenergic state after head injury, and the effects of elevated blood pressure on the injured brain are reviewed, with emphasis placed on the pathophysiologic implications of a disturbance of the blood-brain barrier and of autoregulation in promoting brain swelling and formation of edema.

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