James E Galen

Publication Detail

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Vibrio cholerae enterotoxin genes: nucleotide sequence analysis of DNA encoding ADP-ribosyltransferase.

H A Lockman; J E Galen; J B Kaper (Profiled Authors: James E Galen; James B Kaper)

Journal of bacteriology 1984;159(3):1086-9.

The nucleotide sequence of the DNA encoding the ADP-ribosyltransferase (A1) fragment of cholera enterotoxin was determined. A putative precursor of the A1 peptide contains an 18-amino acid leader peptide, and the mature A1 peptide contains 194 amino acids. The primary structure of the A1 fragment from cholera enterotoxin is more related to that from a human enterotoxigenic Escherichia coli than to that from a porcine enterotoxigenic E. coli.

3 Originating Grant

• 1.

  KAPER, JAMES B

  DEVELOPMENT OF A LIVE ORAL CHOLERA VACCINE

  1 January 1983 - 31 December 1995

  NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

• 2.

  KAPER, JAMES B

  Development of a Live Oral Cholera Vaccine

  1 January 1983 - 30 June 2011

  NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

• 3.

  LEVINE, MYRON M

  FACILITY FOR STUDY OF INFECTIOUS DISEASES, VACCINES

Scientific Context

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