Patrick Hwu

Melanoma Medical Oncology, Cancer Medicine

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Patrick Hwu

• Departments
  Melanoma Medical Oncology
  
  Cancer Medicine
  
  Cancer Center Support Grant (CCSG) Programs
  
  Stem Cell Transplantation and Cellular Therapy
  
  Immunology
  
  Melanoma
  
  

713-563-1728

H-Index:48

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Jessica Ann Chacon; Richard C. Wu; Pariya Sukhumalchandra; Jeffrey J. Molldrem; Amod Sarnaik; Shari Pilon-Thomas; Jeffrey Weber; Patrick Hwu; Laszlo Radvanyi

  Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8⁺ Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy

  PLoS ONE. 2013;8(4).
  0

• 2.

  2013

  Yared Hailemichael; Zhimin Dai; Nina Jaffarzad; Yang Ye; Miguel A Medina; Xue-Fei Huang; Stephanie M Dorta-Estremera; Nathaniel R Greeley; Giovanni Nitti; Weiyi Peng; et al.

  Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

  Nature Medicine. 2013.
  0

• 3.

  2013

  Dennie T. Frederick; Adriano Piris; Alexandria P. Cogdill; Zachary A. Cooper; Cecilia Lezcano; Cristina R. Ferrone; Devarati Mitra; Andrea Boni; Lindsay P. Newton; Chengwen Liu; et al.

  BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma

  Clinical Cancer Research. 2013;19(5):1225-1231.
  0

• 4.

  2013

  Kevin B. Kim; Richard Kefford; Anna C. Pavlick; Jeffrey R. Infante; Antoni Ribas; Jeffrey A. Sosman; Leslie A. Fecher; Michael Millward; Grant A. McArthur; Patrick Hwu; et al.

  Phase II study of the MEK1/MEK2 inhibitor trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor

  Journal of Clinical Oncology. 2013;31(4):482-489.
  1

• 5.

  2013

  Jianjun Gao; Chantale Bernatchez; Padmanee Sharma; Laszlo G. Radvanyi; Patrick Hwu

  Advances in the development of cancer immunotherapies

  Trends in Immunology. 2013;34(2):90-98.
  0

• 6.

  2013

  Chengwen Liu; Weiyi Peng; Chunyu Xu; Yanyan Lou; Minying Zhang; Jennifer A. Wargo; Jie Qing Chen; Haiyan S. Li; Stephanie S. Watowich; Yan Yang; et al.

  BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice

  Clinical Cancer Research. 2013;19(2):393-403.
  1

• 7.

  2013

  Gregory Lizee; Willem W. Overwijk; Laszlo Radvanyi; Jianjun Gao; Padmanee Sharma; Patrick Hwu

  Harnessing the power of the immune system to target cancer

  Annual Review of Medicine. 2013;64:71-90.
  0

• 8.

  2012

  Laszlo G. Radvanyi; Chantale Bernatchez; Minying Zhang; Patricia S. Fox; Priscilla Miller; Jessica Chacon; Richard Wu; Gregory Lizee; Sandy Mahoney; Gladys Alvarado; et al.

  Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients

  Clinical Cancer Research. 2012;18(24):6758-6770.
  4

• 9.

  2012

  Gheath Alatrash; Elizabeth A. Mittendorf; Anna Sergeeva; Pariya Sukhumalchandra; Na Qiao; Mao Zhang; Lisa S. St John; Kathryn Ruisaard; Christine E. Haugen; Zein Al-Atrache; et al.

  Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy

  Journal of Immunology. 2012;189(11):5476-5484.
  0

• 10.

  2012

  Yan Yang; Chengwen Liu; Weiyi Peng; Gregory Lizée; Willem W. Overwijk; Yang Liu; Scott E. Woodman; Patrick Hwu

  Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40

  Blood. 2012;120(23):4533-4543.
  1

• 11.

  2012

  Nitin Chakravarti; Vijay G.R. Peddareddigari; Carla L. Warneke; Marcella M. Johnson; Willem W. Overwijk; Patrick Hwu; Victor G. Prieto

  Differential expression of the g-protein-coupled formyl peptide receptor in melanoma associates with aggressive phenotype

  American Journal of Dermatopathology. 2012.
  0

• 12.

  2012

  Richard W. Joseph; Jeanette E. Eckel-Passow; Ruchi Sharma; Ping Liu; Alexander Parker; John Jakob; Elizabeth Buchbinder; Roland L. Bassett; Michael A. Davies; Patrick Hwu; et al.

  Characterizing the clinical benefit of ipilimumab in patients who progressed on high-dose IL-2

  Journal of Immunotherapy. 2012;35(9):711-715.
  0

• 13.

  2012

  Weiyi Peng; Chengwen Liu; Chunyu Xu; Yanyan Lou; Jieqing Chen; Yan Yang; Hideo Yagita; Willem W. Overwijk; Gregory Lizeé; Laszlo Radvanyi; et al.

  PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines

  Cancer Research. 2012;72(20):5209-5218.
  2

• 14.

  2012

  Rahat Noor; Agop Y. Bedikian; Sandy Mahoney; Roland Bassett Jr.; Kevin Kim; Nicholas Papadopoulos; Wen-Jen Hwu; Patrick Hwu; Jade Homsi

  Comparison of two dosing schedules of palonosetron for the prevention of nausea and vomiting due to interleukin-2-based biochemotherapy

  Supportive Care in Cancer. 2012;20(10):2583-2588.
  0

• 15.

  2012

  Jahan S. Khalili; Shujuan Liu; Tania G. Rodríguez-Cruz; Mayra Whittington; Seth Wardell; Chengwen Liu; Minying Zhang; Zachary A. Cooper; Dennie T. Frederick; Yufeng Li; et al.

  Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma

  Clinical Cancer Research. 2012;18(19):5329-5340.
  5

• 16.

  2012

  Jinhyun Kim; Alexander J. Lazar; Michael A. Davies; Jade Homsi; Nicholas E. Papadopoulos; Wen-Jen Hwu; Agop Y. Bedikian; Scott E. Woodman; Sapna P. Patel; Patrick Hwu; et al.

  BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma

  Journal of Cutaneous Pathology. 2012;39(9):821-825.
  0

• 17.

  2012

  Minying Zhang; Sourindra Maiti; Chantale Bernatchez; Helen Huls; Brian Rabinovich; Richard E. Champlin; Luis M. Vence; Patrick Hwu; Laszlo Radvanyi; Laurence J.N. Cooper

  A new approach to simultaneously quantify both TCR α- and β-chain diversity after adoptive immunotherapy

  Clinical Cancer Research. 2012;18(17):4733-4742.
  2

• 18.

  2012

  John A. Jakob; Roland L. Bassett Jr.; Chaan S. Ng; Jonathan L. Curry; Richard W. Joseph; Gladys C. Alvarado; Michelle L. Rohlfs; Jessie Richard; Jeffrey E. Gershenwald; Kevin B. Kim; et al.

  NRAS mutation status is an independent prognostic factor in metastatic melanoma

  Cancer. 2012;118(16):4014-4023.
  19

• 19.

  2012

  Kevin B. Kim; Victor Prieto; Richard W. Joseph; Abdul H. Diwan; Gary E. Gallick; Nicholas E. Papadopoulos; Agop Y. Bedikian; Luis H. Camacho; Patrick Hwu; Chaan S. Ng; et al.

  A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma

  Melanoma Research. 2012;22(4):294-301.
  0

• 20.

  2012

  Gladys Alvarado; Rahat Noor; Roland Bassett; Nicholas E. Papadopoulos; Kevin B. Kim; Wen-Jen Hwu; Agop Bedikian; Sapna Patel; Patrick Hwu; Michael A. Davies

  Risk of intracranial hemorrhage with anticoagulation therapy in melanoma patients with brain metastases

  Melanoma Research. 2012;22(4):310-315.
  2

• 21.

  2012

  Julie R. Brahmer; Scott S. Tykodi; Laura Q.M. Chow; Wen-Jen Hwu; Suzanne L. Topalian; Patrick Hwu; Charles G. Drake; Luis H. Camacho; John Kauh; Kunle Odunsi; et al.

  Safety and activity of anti-PD-L1 antibody in patients with advanced cancer

  New England Journal of Medicine. 2012;366(26):2455-2465.
  119

• 22.

  2012

  Richard C. Wu; Shujuan Liu; Jessica A. Chacon; Sheng Wu; Yufeng Li; Pariya Sukhumalchandra; James L. Murray; Jeffrey J. Molldrem; Patrick Hwu; Hanspeter Pircher; et al.

  Detection and characterization of a novel subset of CD8 ⁺CD57 ⁺ T cells in metastatic melanoma with an incompletely differentiated phenotype

  Clinical Cancer Research. 2012;18(9):2465-2477.
  0

• 23.

  2012

  David S. Hong; Luis Vence; Gerald Falchook; Laszlo G. Radvanyi; Chengwen Liu; Vicki Goodman; Jeffery J. Legos; Sam Blackman; Antonio Scarmadio; Razelle Kurzrock; et al.

  BRAF(V600) inhibitor GSK2118436 targeted inhibition of mutant BRAF in cancer patients does not impair overall immune competency

  Clinical Cancer Research. 2012;18(8):2326-2335.
  10

• 24.

  2012

  Chantale Bernatchez; Laszlo G. Radvanyi; Patrick Hwu

  Advances in the treatment of metastatic melanoma: Adoptive T-cell therapy

  Seminars in Oncology. 2012;39(2):215-226.
  2

• 25.

  2012

  Chengwen Liu; Carol M. Lewis; Yanyan Lou; Chunyu Xu; Weiyi Peng; Yan Yang; Alexander H. Gelbard; Gregory Lizée; Dapeng Zhou; Willem W. Overwijk; et al.

  Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo

  Journal of Immunotherapy. 2012;35(3):276-282.
  1

• 26.

  2012

  Richard Wu; Marie-Andrée Forget; Jessica Chacon; Chantale Bernatchez; Cara Haymaker; Jie Qing Chen; Patrick Hwu; Laszlo G. Radvanyi

  Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: Current status and future outlook

  Cancer Journal. 2012;18(2):160-175.
  9

• 27.

  2012

  Michael A. Davies; Patricia S. Fox; Nicholas E. Papadopoulos; Agop Y. Bedikian; Wen-Jen Hwu; Alexander J. Lazar; Victor G. Prieto; Kirk S. Culotta; Timothy L. Madden; Quanyun Xu; et al.

  Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma

  Clinical Cancer Research. 2012;18(4):1120-1128.
  6

• 28.

  2012

  Richard W. Joseph; Ryan. J. Sullivan; Robyn Harrell; Katherine Stemke-Hale; David Panka; George Manoukian; Andrew Percy; Roland L. Bassett; Chaan S. Ng; Laszlo Radvanyi; et al.

  Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma

  Journal of Immunotherapy. 2012;35(1):66-72.
  9

• 29.

  2012

  David Z Chang; Ying Ma; Baoan Ji; Yan Liu; Patrick Hwu; James L Abbruzzese; Craig Logsdon; Huamin Wang

  Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression

  Journal of Hematology and Oncology. 2012;5.
  1

• 30.

  2011

  Agop Y. Bedikian; Caimiao Wei; Michelle Detry; Kevin B. Kim; Nicholas E. Papadopoulos; Wen-Jen Hwu; Jade Homsi; Michael Davies; Susan McIntyre; Patrick Hwu

  Predictive factors for the development of brain metastasis in advanced unresectable metastatic melanoma

  American Journal of Clinical Oncology: Cancer Clinical Trials. 2011;34(6):603-610.
  2

• 31.

  2011

  Alessandra Petrelli; Michele Carvello; Andrea Vergani; Kang Mi Lee; Sara Tezza; Ming Du; Sonja Kleffel; Liu Chengwen; Bechara G. Mfarrej; Patrick Hwu; et al.

  IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response

  Diabetes. 2011;60(12):3223-3234.
  1

• 32.

  2011

  Yulia Bronstein; Chaan S. Ng; Patrick Hwu; Wen-Jen Hwu

  Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy

  American Journal of Roentgenology. 2011;197(6):W992-W1000.
  3

• 33.

  2011

  David Z. Chang; Ying Ma; Baoan Ji; Huamin Wang; Defeng Deng; Yan Liu; James L. Abbruzzese; Yong-Jun Liu; Craig D. Logsdon; Patrick Hwu

  Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma

  Clinical Cancer Research. 2011;17(22):7015-7023.
  5

• 34.

  2011

  Mikyoung Chang; Wei Jin; Jae-Hoon Chang; Yichuan Xiao; George C Brittain; Jiayi Yu; Xiaofei Zhou; Yi-Hong Wang; Xuhong Cheng; Pingwei Li; et al.

  The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

  Nature Immunology. 2011;12(10):1002-1009.
  9

• 35.

  2011

  Douglas J. Schwartzentruber; Don Vena; Patrick Hwu

  The authors reply

  New England Journal of Medicine. 2011;365(8):771.
  0

• 36.

  2011

  Agop Y. Bedikian; Jeffrey A. Silverman; Nicholas E. Papadopoulos; Kevin B. Kim; Anne E. Hagey; Anna Vardeleon; Wen-Jen Hwu; Jade Homsi; Michael Davies; Patrick Hwu

  Pharmacokinetics and safety of Marqibo (vincristine sulfate liposomes injection) in cancer patients with impaired liver function

  Journal of Clinical Pharmacology. 2011;51(8):1205-1212.
  9

• 37.

  2011

  Sapna P. Patel; Kevin B. Kim; Nicholas E. Papadopoulos; Wen-Jen Hwu; Patrick Hwu; Victor G. Prieto; Menashe Bar-Eli; Maya Zigler; Andrey Dobroff; Yulia Bronstein; et al.

  A phase II study of gefitinib in patients with metastatic melanoma

  Melanoma Research. 2011;21(4):357-363.
  2

• 38.

  2011

  Richard W. Joseph; Vijay R. Peddareddigari; Ping Liu; Priscilla W. Miller; Willem W. Overwijk; Nebiyou B. Bekele; Merrick I. Ross; Jeffrey E. Lee; Jeffrey E. Gershenwald; Anthony Lucci; et al.

  Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapy

  Clinical Cancer Research. 2011;17(14):4882-4891.
  13

• 39.

  2011

  Douglas J. Schwartzentruber; David H. Lawson; Jon M. Richards; Robert M. Conry; Donald M. Miller; Jonathan Treisman; Fawaz Gailani; Lee Riley; Kevin Conlon; Barbara Pockaj; et al.

  gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

  New England Journal of Medicine. 2011;364(22):2119-2127.
  121

• 40.

  2011

  H.J. Park; H. Qin; S.C. Cha; R. Sharma; Y. Chung; K.S. Schluns; S.S. Neelapu; W.W. Overwijk; P. Hwu; L.W. Kwak

  Induction of TLR4-dependent CD8+ T cell immunity by murine β-defensin2 fusion protein vaccines

  Vaccine. 2011;29(18):3476-3482.
  0

• 41.

  2011

  Michael A. Davies; Ping Liu; Susan McIntyre; Kevin B. Kim; Nicholas Papadopoulos; Wen-Jen Hwu; Patrick Hwu; Agop Bedikian

  Prognostic factors for survival in melanoma patients with brain metastases

  Cancer. 2011;117(8):1687-1696.
  25

• 42.

  2011

  Chantale Bernatchez; Kuichin Zhu; Yufeng Li; Helen Andersson; Constantin Ionnides; Marcelo Fernandez-Vina; Pedro Cano; Laurence Cooper; James Abbruzzese; Patrick Hwu; et al.

  Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals

  Vaccine. 2011;29(16):3021-3030.
  1

• 43.

  2011

  Jeffrey Weber; Michael Atkins; Patrick Hwu; Laszlo Radvanyi; Mario Sznol; Cassian Yee

  White paper on adoptive cell therapy for cancer with tumor-infiltrating lymphocytes: A report of the CTEP subcommittee on adoptive cell therapy

  Clinical Cancer Research. 2011;17(7):1664-1673.
  17

• 44.

  2011

  Gladys C. Alvarado; Nicholas E. Papadopoulos; Wen-Jen Hwu; Agop Y. Bedikian; Jade Homsi; Jeffrey N. Myers; Yulia Bronstein; Roland L. Bassett; Patrick Hwu; Kevin B. Kim

  Pelvic computed tomography scans for surveillance in patients with primary melanoma in the head and neck

  Melanoma Research. 2011;21(2):127-130.
  0

• 45.

  2011

  Jessica Ann Hernandez-Chacon; Yufeng Li; Richard C. Wu; Chantale Bernatchez; Yijun Wang; Jeffrey S. Weber; Patrick Hwu; Laszlo G. Radvanyi

  Costimulation through the CD137/4-1BB pathway protects human melanoma tumor-infiltrating lymphocytes from activation-induced cell death and enhances antitumor effector function

  Journal of Immunotherapy. 2011;34(3):236-250.
  15

• 46.

  2011

  Yanyan Lou; Chengwen Liu; Gregory Lizée; Weiyi Peng; Chunyu Xu; Yang Ye; Brian A. Rabinovich; Yared Hailemichael; Alexander Gelbard; Dapeng Zhou; et al.

  Antitumor activity mediated by CpG: The route of administration is critical

  Journal of Immunotherapy. 2011;34(3):279-288.
  3

• 47.

  2011

  Yufeng Li; Clay L. Efferson; Rajagopal Ramesh; George E. Peoples; Patrick Hwu; Constantin G. Ioannides

  A peptidoglycan monomer with the glutamine to serine change and basic peptides bind in silico to TLR-2 (403-455)

  Cancer Immunology, Immunotherapy. 2011;60(4):515-524.
  3

• 48.

  2011

  Agop Y. Bedikian; Marcella M. Johnson; Carla L. Warneke; Nicholas E. Papadopoulos; Kevin B. Kim; Wen-Jen Hwu; Susan McIntyre; Michelle Rohlfs; Jade Homsi; Patrick Hwu

  Does complete response to systemic therapy in patients with stage IV melanoma translate into long-term survival?

  Melanoma Research. 2011;21(1):84-90.
  2

• 49.

  2011

  James M. Balwit; Patrick Hwu; Walter J. Urba; Francesco M. Marincola

  The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: A summary of the 2010 program

  Journal of Translational Medicine. 2011;9.
  5

• 50.

  2011

  Judy Ahrar; Sanjay Gupta; Joe Ensor; Kamran Ahrar; David C. Madoff; Michael J. Wallace; Ravi Murthy; Alda Tam; Patrick Hwu; Agop Y. Bedikian

  Response, survival, and prognostic factors after hepatic arterial chemoembolization in patients with liver metastases from cutaneous melanoma

  Cancer Investigation. 2011;29(1):49-55.
  3

• 51.

  2011

  Jade Homsi; Joshua C. Grimm; Patrick Hwu

  Immunotherapy of melanoma: An update

  Surgical Oncology Clinics of North America. 2011;20(1):145-163.
  2

• 52.

  2010

  Natalia Martin-Orozco; Yufeng Li; Yijun Wang; Shijuan Liu; Patrick Hwu; Yong-Jun Liu; Chen Dong; Laszlo Radvanyi

  Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells

  Cancer Research. 2010;70(23):9581-9590.
  11

• 53.

  2010

  Wen-Jen Hwu; Robert D. Knight; Madhavi Patnana; Roland Bassett; Nicholas E. Papadopoulos; Kevin B. Kim; Patrick Hwu; Agop Bedikian

  Phase i safety study of lenalidomide and dacarbazine in patients with metastatic melanoma previously untreated with systemic chemotherapy

  Melanoma Research. 2010;20(6):501-506.
  2

• 54.

  2010

  Jade Homsi; Agop Y. Bedikian; Nicholas E. Papadopoulos; Kevin B. Kim; Wen-Jen Hwu; Sandy L. Mahoney; Patrick Hwu

  Phase 2 open-label study of weekly docosahexaenoic acid-paclitaxel in patients with metastatic uveal melanoma

  Melanoma Research. 2010;20(6):507-510.
  6

• 55.

  2010

  Weiyi Peng; Yang Ye; Brian A. Rabinovich; Chengwen Liu; Yanyan Lou; Minying Zhang; Mayra Whittington; Yan Yang; Willem W. Overwijk; Gregory Lizée; et al.

  Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses

  Clinical Cancer Research. 2010;16(22):5458-5468.
  13

• 56.

  2010

  Dan Li; Yufeng Li; Jessica A. Hernandez; Rebecca Patenia; Tae Kon Kim; Jahan Khalili; Mark C. Dougherty; Patrick J. Hanley; Catherine M. Bollard; Krishna V. Komanduri; et al.

  Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs

  Journal of Immunotherapy. 2010;33(9):975-982.
  1

• 57.

  2010

  Roberto Carreño; Wells S. Brown; Dan Li; Jessica A. Hernandez; Yang Wang; Tae Kon Kim; John W. Craft Jr.; Krishna V. Komanduri; Laszlo G. Radvanyi; Patrick Hwu; et al.

  2E8 binds to the high affinity I-domain in a metal ion-dependent manner: A second generation monoclonal antibody selectively targeting activated LFA-1

  Journal of Biological Chemistry. 2010;285(43):32860-32868.
  3

• 58.

  2010

  Sanjay Gupta; Agop Y. Bedikian; Judy Ahrar; Joe Ensor; Kamran Ahrar; David C. Madoff; Michael J. Wallace; Ravi Murthy; Alda Tam; Patrick Hwu

  Hepatic artery chemoembolization in patients with ocular melanoma metastatic to the liver: Response, survival, and prognostic factors

  American Journal of Clinical Oncology: Cancer Clinical Trials. 2010;33(5):474-480.
  3

• 59.

  2010

  Patrick Hwu

  Treating cancer by targeting the immune system

  New England Journal of Medicine. 2010;363(8):779-781.
  13

• 60.

  2010

  R.F. Chemaly; P.S. Sharma; S. Youssef; D. Gerber; P. Hwu; S.S. Hanmod; Y. Jiang; R.Y. Hachem; I.I. Raad

  The efficacy of catheters coated with minocycline and rifampin in the prevention of catheter-related bacteremia in cancer patients receiving high-dose interleukin-2

  International Journal of Infectious Diseases. 2010;14(7):e548-e552.
  1

• 61.

  2010

  Michelle D. Williams; Bita Esmaeli; Aydin Soheili; Ronit Simantov; Dan S. Gombos; Agop Y. Bedikian; Patrick Hwu

  GPNMB expression in uveal melanoma: A potential for targeted therapy

  Melanoma Research. 2010;20(3):184-190.
  6

• 62.

  2010

  Shujuan Liu; Tamara Etto; Tania Rodríguez-Cruz; Yufeng Li; Chenghan Wu; Orenthial J. Fulbright; Patrick Hwu; Laszlo Radvanyi; Gregory Lizee

  TGF-β1 induces preferential rapid expansion and persistence of tumor antigen-specific CD8⁺ T cells for adoptive immunotherapy

  Journal of Immunotherapy. 2010;33(4):371-381.
  2

• 63.

  2010

  Chan Yoon; Nicholas E. Papadopoulos; Luis H. Camacho; Susan McIntyre; Gladys C. Alvarado; Agop Y. Bedikian; Patrick Hwu; Kevin B. Kim

  The clinical efficacy of combination of docetaxel and temozolomide in previously treated patients with stage IV melanoma

  Melanoma Research. 2010;20(1):43-47.
  4

• 64.

  2010

  Eric L Chang; Patrick Hwu

  Whole-brain radiation therapy in melanoma: an open question - Authors' reply

  The Lancet Oncology. 2010;11(1):13-14.
  0

• 65.

  2010

  Yufeng Li; Shujuan Liu; Jessica Hernandez; Luis Vence; Patrick Hwu; Laszlo Radvanyi

  MART-1-specific melanoma tumor-infiltrating lymphocytes maintaining CD28 expression have improved survival and expansion capability following antigenic restimulation in vitro

  Journal of Immunology. 2010;184(1):452-465.
  22

• 66.

  2009

  Natalia Martin-Orozco; Pawel Muranski; Yeonseok Chung; Xuexian O. Yang; Tomohide Yamazaki; Sijie Lu; Patrick Hwu; Nicholas P. Restifo; Willem W. Overwijk; Chen Dong

  T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

  Immunity. 2009;31(5):787-798.
  173

• 67.

  2009

  Nicholas E. Papadopoulos; Agop Bedikian; Sigrid Ring; Kevin B. Kim; Wen-Jen Hwu; Donna L. Gerber; Jade Homsi; Patrick Hwu

  Phase I/II study of a cisplatin-taxol-dacarbazine regimen in metastatic melanoma

  American Journal of Clinical Oncology: Cancer Clinical Trials. 2009;32(5):509-514.
  4

• 68.

  2009

  Agop Y. Bedikian; Nicholas E. Papadopoulos; Kevin B. Kim; Wen-Jen Hwu; Jade Homsi; Michelle R. Glass; Suzanne Cain; Patrick Rudewicz; Laurent Vernillet; Patrick Hwu

  A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma

  Cancer Investigation. 2009;27(7):756-763.
  26

• 69.

  2009

  Scott E. Woodman; Jonathan C. Trent; Katherine Stemke-Hale; Alexander J. Lazar; Sabrina Pricl; Giovanni M. Pavan; Maurizio Fermeglia; Y. N. Vashisht Gopal; Dan Yang; Donald A. Podoloff; et al.

  Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates

  Molecular Cancer Therapeutics. 2009;8(8):2079-2085.
  61

• 70.

  2009

  Jade. Homsi; Agop Y. Bedikian; Kevin B. Kim; Nicholas E. Papadopoulos; Wen-Jen. Hwu; Sandy L. Mahoney; Patrick Hwu

  Phase 2 open-label study of weekly docosahexaenoic acid-paclitaxel in cutaneous and mucosal metastatic melanoma patients

  Melanoma Research. 2009;19(4):238-242.
  6

• 71.

  2009

  Patrick Hwu

  Promising results from Phase III clinical trial of a peptide vaccine for advanced melanoma

  Immunotherapy. 2009;1(4):521.
  0

• 72.

  2009

  Andrew G. Sikora; Nina Jaffarzad; Yared Hailemichael; Alexander Gelbard; Spencer W. Stonier; Kimberly S. Schluns; Loredana Frasca; Yanyan Lou; Chengwen Liu; Helen A. Andersson; et al.

  IFN-α enhances peptide vaccine-induced CD8⁺ T cell numbers, effector function, and antitumor activity

  Journal of Immunology. 2009;182(12):7398-7407.
  45

• 73.

  2009

  Kevin B. Kim; Wen-Jen Hwu; Nicholas E. Papadopoulos; Agop Y. Bedikian; Luis H. Camacho; Chaan Ng; Ingrid M. Hernandez; Angela M. Frost; Monica A. Jack; Patrick Hwu

  Phase i study of the combination of docetaxel, temozolomide and cisplatin in patients with metastatic melanoma

  Cancer Chemotherapy and Pharmacology. 2009;64(1):161-167.
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  Prakash Thapa; Guodong Zhang; Chengfeng Xia; Alexander Gelbard; Willem W. Overwijk; Chengwen Liu; Patrick Hwu; David Z. Chang; Amy Courtney; Jagannadha K. Sastry; et al.

  Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy

  Vaccine. 2009;27(25-26):3484-3488.
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  Kevin B. Kim; Sewa S. Legha; Rene Gonzalez; Clay M. Anderson; Marcella M. Johnson; Ping Liu; Nicholas E. Papadopoulos; Omar Eton; Carl Plager; Antonio C. Buzaid; et al.

  A randomized phase III trial of biochemotherapy versus interferon-α- 2b for adjuvant therapy in patients at high risk for melanoma recurrence

  Melanoma Research. 2009;19(1):42-49.
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  Yufeng Li; Shujuan Liu; Kim Margolin; Patrick Hwu

  Summary of the primer on tumor immunology and the biological therapy of cancer

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  A.J. Montero; C.M. Diaz-Montero; R.E. Millikan; J. Liu; K.-A. Do; S. Hodges; E. Jonasch; B.W. McIntyre; P. Hwu; N. Tannir

  Cytokines and angiogenic factors in patients with metastatic renal cell carcinoma treated with interferon-α: Association of pretreatment serum levels with survival

  Annals of Oncology. 2009;20(10):1682-1687.
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  2009

  Zita Dubauskas; Joy Kunishige; Victor G. Prieto; Eric Jonasch; Patrick Hwu; Nizar M. Tannir

  Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with Sorafenib

  Clinical Genitourinary Cancer. 2009;7(1):20-23.
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  2008

  Holly L. Bartell; Agop Y. Bedikian; Nicholas E. Papadopoulos; Tina K. Dett; Matthew T. Ballo; Jeffrey N. Myers; Patrick Hwu; Kevin B. Kim

  Biochemotherapy in patients with advanced head and neck mucosal melanoma

  Head and Neck. 2008;30(12):1592-1598.
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  2008

  Brian A. Rabinovich; Yang Ye; Tamara Etto; Qing Chen Jie; Hyam I. Levitsky; Willem W. Overwijk; Laurence J. N. Cooper; Juri Gelovani; Patrick Hwu

  Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer

  Proceedings of the National Academy of Sciences of the United States of America. 2008;105(38):14342-14346.
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  Cindy S. Hwang; Victor G. Prieto; Abdul H. Diwan; Gregory Lizee; Julie A. Ellerhorst; Suhendan Ekmekcioglu; Ping Liu; Omar Eton; Sandra A. Kinney; Elizabeth A. Grimm; et al.

  Changes in pERK1/2 and pAKT expression in melanoma lesions after imatinib treatment

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  Agop Y. Bedikian; Marcella M. Johnson; Carla L. Warneke; Nicholas E. Papadopoulos; Kevin Kim; Wen-Jen Hwu; Susan McIntyre; Patrick Hwu

  Prognostic factors that determine the long-term survival of patients with unresectable metastatic melanoma

  Cancer Investigation. 2008;26(6):624-633.
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  2008

  Agop Y. Bedikian; Marcella M. Johnson; Carla L. Warneke; Susan McIntyre; Nicholas Papadopoulos; Wen-Jen Hwu; Kevin Kim; Patrick Hwu

  Systemic therapy for unresectable metastatic melanoma: Impact of biochemotherapy on long-term survival

  Journal of Immunotoxicology. 2008;5(2):201-207.
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  Chengwen Liu; Yanyan Lou; Gregory Lizée; Hong Qin; Shujuan Liu; Brian Rabinovich; Grace J. Kim; Yi-Hong Wang; Yang Ye; Andrew G. Sikora; et al.

  Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice

  Journal of Clinical Investigation. 2008;118(3):1165-1175.
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  Seung-Tae Lee; Shujuan Liu; Laszlo Radvanyi; Pariya Sukhumalchandra; Jeffrey J. Molldrem; Eric D. Wieder; Patrick Hwu; Yong-Jun Liu; Larry W. Kwak; Gregory Lizée; et al.

  A novel strategy for rapid and efficient isolation of human tumor-specific CD4⁺ and CD8⁺ T-cell clones

  Journal of Immunological Methods. 2008;331(1-2):13-26.
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  A. Quintás-Cardama; A.J. Lazar; S.E. Woodman; K. Kim; P. Hwu

  Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib

  Nature Clinical Practice Oncology. 2008;5(12):737-740.
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  2007

  Kuichun Zhu; Hong Qin; Soung-Chul Cha; Sattva S. Neelapu; Willem Overwijk; Gregory A. Lizee; James L. Abbruzzese; Patrick Hwu; Laszlo Radvanyi; Larry W. Kwak; et al.

  Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models

  Vaccine. 2007;25(46):7955-7961.
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  Shujuan Liu; Gregory Lizée; Yanyan Lou; Chengwen Liu; Willem W. Overwijk; Gang Wang; Patrick Hwu

  IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells

  International Immunology. 2007;19(10):1213-1221.
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  2007

  Gregory Lizée; Mayra A. Cantu; Patrick Hwu

  Less Yin, more Yang: Confronting the barriers to cancer immunotherapy

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  2007

  Kuichun Zhu; Gregory Lizee; Pedro Cano; Marcelo Fernando-Vina; Baoan Ji; James L. Abbruzzese; Patrick Hwu; Laszlo Radvanyi; David Z. Chang

  HLA-A0201 positive pancreatic cell lines: New findings and discrepancies

  Cancer Immunology, Immunotherapy. 2007;56(5):719-724.
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  2007

  A. Murphy; J.A. Westwood; L.E. Brown; M.W.L. Teng; M. Moeller; Y. Xu; M.J. Smyth; P. Hwu; P.K. Darcy; M.H. Kershaw

  Antitumor activity of dual-specific T cells and influenza virus

  Cancer Gene Therapy. 2007;14(5):499-508.
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  2007

  William E. Carson III; Andrew Allen; Louis M. Weiner; Martin A. Cheever; Bernard A. Fox; Ulrich Keilholz; Jon M. Wigginton; Paul M. Sondel; Michael B. Atkins; Patrick Hwu

  Immunotherapy comes of age: Overview of the 21^st Annual Meeting and associated programs of the International Society for Biological Therapy of Cancer: Los Angeles, CA, USA, 27-29 October 2006

  Expert Opinion on Biological Therapy. 2007;7(3):419-422.
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  2007

  Yanyan Lou; Chengwen Liu; Grace J. Kim; Yong-Jun Liu; Patrick Hwu; Gang Wang

  Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific antitumor immune responses

  Journal of Immunology. 2007;178(3):1534-1541.
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  2007

  M.C. Leslie; Y.-J. Zhao; L.B. Lachman; P. Hwu; G.-J. Wu; M. Bar-Eli

  Erratum: Immunization against MUC18/MCAM, a novel antigen that drives melanoma invasion and metastasis (Gene Therapy (2007) vol. 14 (316-323) 10.1038/sj.3302864)

  Gene Therapy. 2007;14(4):382.
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  M.C. Leslie; Y.J. Zhao; L.B. Lachman; P. Hwu; M. Bar-Eli

  Immunization against MUC18/MCAM, a novel antigen that drives melanoma invasion and metastasis

  Gene Therapy. 2007;14(4):316-323.
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  2006

  Michal Lotem; Yangbing Zhao; John Riley; Patrick Hwu; Richard A. Morgan; Steven A. Rosenberg; Maria R. Parkhurst

  Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors

  Journal of Immunotherapy. 2006;29(6):616-627.
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  Michael H. Kershaw; Jennifer A. Westwood; Linda L. Parker; Gang Wang; Zelig Eshhar; Sharon A. Mavroukakis; Donald E. White; John R. Wunderlich; Silvana Canevari; Linda Rogers-Freezer; et al.

  A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

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  Amelia Grover; Grace J. Kim; Gregory Lizée; Mary Tschoi; Gang Wang; John R. Wunderlich; Steven A. Rosenberg; Sam T. Hwang; Patrick Hwu

  Intralymphatic dendritic cell vaccination induces tumor antigen - specific, skin-homing T lymphocytes

  Clinical Cancer Research. 2006;12(19):5801-5808.
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  2006

  Katsutoshi Ozaki; Ai Hishiya; Keiko Hatanaka; Hideaki Nakajima; Gang Wang; Patrick Hwu; Toshio Kitamura; Keiya Ozawa; Warren J. Leonard; Tetsuya Nosaka

  Overexpression of interleukin 21 induces expansion of hematopoietic progenitor cells

  International Journal of Hematology. 2006;84(3):224-230.
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  Patrick Hwu; Agop Y. Bedikian; Elizabeth A. Grimm

  Challenges of chemosensitivity testing

  Clinical Cancer Research. 2006;12(18):5258-5259.
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  2006

  Gregory Lizée; Laszlo G. Radvanyi; Willem W. Overwijk; Patrick Hwu

  Improving antitumor immune responses by circumventing immunoregulatory cells and mechanisms

  Clinical Cancer Research. 2006;12(16):4794-4803.
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  Michael B. Atkins; David E. Elder; Richard Essner; Keith T. Flaherty; Thomas F. Gajewski; Frank G. Haluska; Patrick Hwu; Ulrich Keilholz; John M. Kirkwood; et al.

  Innovations and challenges in melanoma: summary statement from the first Cambridge conference

  Clinical Cancer Research. 2006;12(7 II):2291s-2296s.
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  Gregory Lizée; Laszlo G. Radvanyi; Willem W. Overwijk; Patrick Hwu

  Immunosuppression in melanoma immunotherapy: Potential opportunities for intervention

  Clinical Cancer Research. 2006;12(7 II):2359s-2365s.
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  Matthew T. Ballo; Merrick I. Ross; Janice N. Cormier; Jeffrey N. Myers; Jeffrey E. Lee; Jeffrey E. Gershenwald; Patrick Hwu; Gunar K. Zagars

  Combined-modality therapy for patients with regional nodal metastases from melanoma

  International Journal of Radiation Oncology Biology Physics. 2006;64(1):106-113.
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  2004

  Katsutoshi Ozaki; Rosanne Spolski; Rachel Ettinger; Hyoung-Fyo Kim; Gang Wang; Chen-Feng Qi; Patrick Hwu; Daniel J. Shaffer; Shreeram Akilesh; Derry C. Roopenian; et al.

  Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6

  Journal of Immunology. 2004;173(9):5361-5371.
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  Yanyan Lou; Gang Wang; Gregory Lizée; Grace J. Kim; Steven E. Finkelstein; Chiguang Feng; Nicholas P. Restifo; Patrick Hwu

  Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo

  Cancer Research. 2004;64(18):6783-6790.
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  Michael Von Bergwelt-Baildon; Joachim L. Schultze; Britta Maecker; Isaura Menezes; Lee M. Nadler; Réjean Lapointe; Jacques Thibodeau; Patrick Hwu

  Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer res 2003;63:2836-43 (multiple letters)

  Cancer Research. 2004;64(11):4055-4057.
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  2004

  Matthew T. Ballo; Gunar K. Zagars; Jeffrey E. Gershenwald; Jeffrey E. Lee; Paul F. Mansfield; Kevin B. Kim; Luis H. Camacho; Patrick Hwu; Merrick I. Ross

  A critical assessment of adjuvant radiotherapy for inguinal lymph node metastases from melanoma

  Annals of Surgical Oncology. 2004;11(12):1079-1084.
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  2003

  Gang Wang; Mary Tschoi; Rosanne Spolski; Yanyan Lou; Katsutoshi Ozaki; Chiguang Feng; Grace Kim; Warren J. Leonard; Patrick Hwu

  In Vivo Antitumor Activity of Interleukin 21 Mediated by Natural Killer Cells

  Cancer Research. 2003;63(24):9016-9022.
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  Steven A. Rosenberg; James C. Yang; Paul F. Robbins; John R. Wunderlich; Patrick Hwu; Richard M. Sherry; Douglas J. Schwartzentruber; Suzanne L. Topalian; Nicholas P. Restifo; et al.

  Cell transfer therapy for cancer: Lessons from sequential treatments of a patient with metastatic melanoma

  Journal of Immunotherapy. 2003;26(5):385-393.
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  James C. Yang; Richard M. Sherry; Seth M. Steinberg; Suzanne L. Topalian; Douglas J. Schwartzentruber; Patrick Hwu; Claudia A. Seipp; Linda Rogers-Freezer; Kathleen E. Morton; Donald E. White; et al.

  Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer

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  Steven A. Rosenberg; James C. Yang; Douglas J. Schwartzentruber; Patrick Hwu; Suzanne L. Topalian; Richard M. Sherry; Nicholas P. Restifo; John R. Wunderlich; Claudia A. Seipp; et al.

  Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma

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  James C. Yang; Leah Haworth; Richard M. Sherry; Patrick Hwu; Douglas J. Schwartzentruber; Suzanne L. Topalian; Seth M. Steinberg; Helen X. Chen; Steven A. Rosenberg

  A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer

  New England Journal of Medicine. 2003;349(5):427-434.
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  Giao Q. Phan; James C. Yang; Richard M. Sherry; Patrick Hwu; Suzanne L. Topalian; Douglas J. Schwartzentruber; Nicholas P. Restifo; Leah R. Haworth; Claudia A. Seipp; et al.

  Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

  Proceedings of the National Academy of Sciences of the United States of America. 2003;100(14):8372-8377.
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  Giao Q. Phan; Christopher E. Touloukian; James C. Yang; Nicholas P. Restifo; Richard M. Sherry; Patrick Hwu; Suzanne L. Topalian; Douglas J. Schwartzentruber; Claudia A. Seipp; et al.

  Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens

  Journal of Immunotherapy. 2003;26(4):349-356.
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  Réjean Lapointe; Angélique Bellemare-Pelletier; Franck Housseau; Jacques Thibodeau; Patrick Hwu

  CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells

  Cancer Research. 2003;63(11):2836-2843.
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  Steven A. Rosenberg; James C. Yang; Richard M. Sherry; Patrick Hwu; Suzanne L. Topalian; Douglas J. Schwartzentruber; Nicholas P. Restifo; Leah R. Haworth; Claudia A. Seipp; et al.

  Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen

  Human Gene Therapy. 2003;14(8):709-714.
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  Fiona O'Reilly; Elizabeth Feldman; James Yang; Patrick Hwu; Maria L. Turner

  Recurring cutaneous eruption in a patient with metastatic renal cell carcinoma being treated with high-dose interleukin 2

  Journal of the American Academy of Dermatology. 2003;48(4):602-604.
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  Michael H. Kershaw; Jennifer A. Westwood; Patrick Hwu

  Dual-specific T cells combine proliferation and antitumor activity

  Nature Biotechnology. 2002;20(12):1221-1227.
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  2002

  J. Mark Sloan; Michael H. Kershaw; Christopher E. Touloukian; Rejean Lapointe; Paul F. Robbins; Nicholas P. Restifo; Patrick Hwu

  MHC class I and class II presentation of tumor antigen in retrovirally and adenovirally transduced dendritic cells

  Cancer Gene Therapy. 2002;9(11):946-950.
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  Mark E. Dudley; John R. Wunderlich; Paul F. Robbins; James C. Yang; Patrick Hwu; Douglas J. Schwartzentruber; Suzanne L. Topalian; Richard Sherry; Nicholas P. Restifo; et al.

  Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

  Science. 2002;298(5594):850-854.
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  Christopher E. Touloukian; Wolfgang W. Leitner; Paul F. Robbins; Yong F. Li; Xiaoqiang Kang; Rejean Lapointe; Patrick Hwu; Steven A. Rosenberg; Nicholas P. Restifo

  Expression of a "self-"antigen by human tumor cells enhances tumor antigen-specific CD4⁺ T-cell function

  Cancer Research. 2002;62(18):5144-5147.
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  R.E. Royal; M.H. Kershaw; M.E. Reeves; G. Wang; T. Daly; J. Treisman; J. Lam; P. Hwu

  Increased functional expression of transgene in primary human lymphocytes using retroviral vectors modified with IRES and splicing motifs

  Gene Therapy. 2002;9(16):1085-1092.
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  2002

  Patrick Hwu; Ralph S. Freedman

  The immunotherapy of patients with ovarian cancer

  Journal of Immunotherapy. 2002;25(3):189-201.
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  2002

  Carlos E. Marroquin; Jennifer A. Westwood; Rejean Lapointe; Arnold Mixon; John R. Wunderlich; Dania Caron; Steven A. Rosenberg; Patrick Hwu

  Mobilization of dendritic cell precursors in patients with cancer by Flt3 ligand allows the generation of higher yields of cultured dendritic cells

  Journal of Immunotherapy. 2002;25(3):278-288.
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  John F. Toso; Rejean Lapointe; Patrick Hwu

  CD40 ligand and lipopolysaccharide enhance the in vitro generation of melanoma-reactive T-cells

  Journal of Immunological Methods. 2002;259(1-2):181-190.
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  John F Toso; Vee J Gill; Patrick Hwu; Francesco M Marincola; Nicholas P Restifo; Douglas J Schwartzentruber; Richard M Sherry; Suzanne L Topalian; James C Yang; Frida Stock; et al.

  Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma

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  Helen Y. Wang; Tihui Fu; Gang Wang; Gang Zeng; Donna M. Perry-Lalley; James C. Yang; Nicholas P. Restifo; Patrick Hwu; Rong-Fu Wang

  Induction of CD4⁺ T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells

  Journal of Clinical Investigation. 2002;109(11):1463-1470.
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  Michael H. Kershaw; Patrick Hwu; Gang Wang; Jennifer A. Westwood; Russell K. Pachynski; H. Lee Tiffany; Francesco M. Marincola; Ena Wang; Howard A. Young; Philip M. Murphy

  Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2

  Human Gene Therapy. 2002;13(16):1971-1980.
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  Mark E. Dudley; John R. Wunderlich; James C. Yang; Patrick Hwu; Douglas J. Schwartzentruber; Suzanne L. Topalian; Richard M. Sherry; Francesco M. Marincola; Susan F. Leitman; et al.

  A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma

  Journal of Immunotherapy. 2002;25(3):243-251.
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  M.H. Kershaw; C. Hsu; W. Mondesire; L.L. Parker; G. Wang; W.W. Overwijk; R. Lapointe; J.C. Yang; R.-F. Wang; N.P. Restifo; et al.

  Immunization against endogenous retroviral tumor-associated antigens

  Cancer Research. 2001;61(21):7920-7924.
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  R. Lapointe; R.E. Royal; M.E. Reeves; I. Altomare; P.F. Robbins; P. Hwu

  Retrovirally transduced human dendritic cells can generate T cells recognizing multiple MHC class I and class II epitopes from the melanoma antigen glycoprotein 100

  Journal of Immunology. 2001;167(8):4758-4764.
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  S. Moir; A. Malaspina; K.M. Ogwaro; E.T. Donoghue; C.W. Hallahan; L.A. Ehler; S. Liu; J. Adelsberger; R. Lapointe; P. Hwu; et al.

  HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals

  Proceedings of the National Academy of Sciences of the United States of America. 2001;98(18):10362-10367.
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  M.E. Dudley; J. Wunderlich; M.I. Nishimura; D. Yu; J.C. Yang; S.L. Topalian; D.J. Schwartzentruber; P. Hwu; F.M. Marincola; R. Sherry; et al.

  Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma

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  M.H. Kershaw; J.A. Westwood; Z. Zhu; L. Witte; S.K. Libutti; P. Hwu

  Generation of gene-modified T cells reactive against the angiogenic kinase insert domain-containing receptor (KDR) found on tumor vasculature

  Human Gene Therapy. 2000;11(18):2445-2452.
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  2000

  L.L. Parker; M.T. Do; J.A. Westwood; J.R. Wunderlich; M.E. Dudley; S.A. Rosenberg; P. Hwu

  Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer

  Human Gene Therapy. 2000;11(17):2377-2387.
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  2000

  N. Chinnasamy; D. Chinnasamy; J.F. Toso; R. Lapointe; F. Candotti; R.A. Morgan; P. Hwu

  Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors

  Human Gene Therapy. 2000;11(13):1901-1909.
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  Patrick Hwu; Mark X. Du; Réjean Lapointe; My Do; Milton W. Taylor; Howard A. Young

  Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation

  Journal of Immunology. 2000;164(7):3596-3599.
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  Andrew L. Feldman; Nicholas P. Restifo; H. Richard Alexander; David L. Bartlett; Patrick Hwu; Prem Seth; Steven K. Libutti

  Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice

  Cancer Research. 2000;60(6):1503-1506.
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  Réjean Lapointe; John F. Toso; Cherie Butts; Howard A. Young; Patrick Hwu

  Human dendritic cells require multiple activation signals for the efficient generation of tumor antigen-specific T lymphocytes

  European Journal of Immunology. 2000;30(11):3291-3298.
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  Tom Daly; Richard E. Royal; Michael H. Kershaw; Jonathan Treisman; Gang Wang; Weiping Li; Dorothee Herlyn; Zelig Eshhar; Patrick Hwu

  Recognition of human colon cancer by T cells transduced with a chimeric receptor gene

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  Steven A. Rosenberg; James C. Yang; Douglas J. Schwartzentruber; Patrick Hwu; Francesco M. Marincola; Suzanne L. Topalian; Nicholas P. Restifo; Mario Sznol; Susan L. Schwarz; et al.

  Impact of cytokine administration on the generation of antitumor reactivity in patients with metastatic melanoma receiving a peptide vaccine

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  Timothy M. Clay; Mary C. Custer; Jessica Sachs; Patrick Hwu; Steven A. Rosenberg; Michael I. Nishimura

  Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity

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  Svetlana D. Pack; Jayaprakash D. Karkera; Zhengping Zhuang; Evgenia D. Pak; Kannan V. Balan; Patrick Hwu; Wong-Sang Park; Thu Pham; David O. Ault; Moshe Glaser; et al.

  Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations

  Genes Chromosomes and Cancer. 1999;25(2):160-168.
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  Vincenzo Bronte; Dale B. Chappell; Elisa Apolloni; Anna Cabrelle; Michael Wang; Patrick Hwu; Nicholas P. Restifo

  Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8⁺ T cell responses by dysregulating antigen-presenting cell maturation

  Journal of Immunology. 1999;162(10):5728-5737.
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  Steven A. Rosenberg; James C. Yang; Douglas J. Schwartzentruber; Patrick Hwu; Francesco M. Marincola; Suzanne L. Topalian; Claudia A. Seipp; Jan H. Einhorn; Donald E. White; et al.

  Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b

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  Susan Moir; Réjean Lapointe; Angela Malaspina; Mario Ostrowski; Charsey E. Cole; Tae-Wook Chun; Joseph Adelsberger; Michael Baseler; Patrick Hwu; et al.

  CD40-mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: Potential role of B lymphocytes as a viral reservoir

  Journal of Virology. 1999;73(10):7972-7980.
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  Peter C. Wu; H. Richard Alexander; James Huang; Patrick Hwu; Michael Gnant; Adam C. Berger; Ewa Turner; Olga Wilson; Steven K. Libutti

  In vivo sensitivity of human melanoma to tumor necrosis factor (TNF)-α is determined by tumor production of the novel cytokine endothelial-monocyte activating polypeptide II (EMAPII)

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  Steven A. Rosenberg; Yifan Zhai; James C. Yang; Douglas J. Schwartzentruber; Patrick Hwu; Francesco M. Marincola; Suzanne L. Topalian; Nicholas P. Restifo; Claudia A. Seipp; et al.

  Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens

  Journal of the National Cancer Institute. 1998;90(24):1894-1900.
  229

• 150.

  1998

  Steven A. Rosenberg; James C. Yang; Douglas J. Schwartzentruber; Patrick Hwu; Francesco M. Marincola; Suzanne L. Topalian; Nicholas P. Restifo; Mark E. Dudley; Susan L. Schwarz; et al.

  Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

  Nature Medicine. 1998;4(3):321-327.
  1443

• 151.

  1998

  Gang Wang; Rajesh K. Chopra; Richard E. Royal; James C. Yang; Steven A. Rosenberg; Patrick Hwu

  A T cell-independent antitumor response in mice with bone marrow cells retrovirally transduced with an antibody/Fc-γ chain chimetic receptor gene recognizing a human ovarian cancer antigen

  Nature Medicine. 1998;4(2):168-172.
  45

• 152.

  1997

  Jennifer M. Specht; Gang Wang; My T. Do; John S. Lam; Richard E. Royal; Mark E. Reeves; Steven A. Rosenberg; Patrick Hwu

  Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases

  Journal of Experimental Medicine. 1997;186(8):1213-1221.
  259

• 153.

  1997

  P. Hwu

  Current challenges in cancer gene therapy

  Journal of Internal Medicine, Supplement. 1997;242(740):109-114.
  13

• 154.

  1996

  Mark E. Reeves; Richard E. Royal; John S. Lam; Steven A. Rosenberg; Patrick Hwu

  Retroviral transduction of human dendritic cells with a tumor-associated antigen gene

  Cancer Research. 1996;56(24):5672-5677.
  198

• 155.

  1996

  John S. Lam; Mark E. Reeves; Robert Cowherd; Steven A. Rosenberg; Patrick Hwu

  Improved gene transfer into human lymphocytes using retroviruses with the gibbon ape leukemia virus envelope

  Human Gene Therapy. 1996;7(12):1415-1422.
  55

• 156.

  1996

  Ronald S. Chamberlain; Miles W. Carroll; Vincenzo Bronte; Patrick Hwu; Steven Warren; James C. Yang; Michael Nishimura; Bernard Moss; Steven A. Rosenberg; et al.

  Costimulation enhances the active immunotherapy effect of recombinant anticancer vaccines

  Cancer Research. 1996;56(12):2832-2836.
  72

• 157.

  1996

  Richard E. Royal; Seth M. Steinberg; Robert S. Krouse; Glenroy Heywood; Donald E. White; Patrick Hwu; Franco M. Marincola; David R. Parkinson; Douglas J. Schwartzentruber; Suzanne L. Topalian; et al.

  Correlates of response to IL-2 therapy in patients treated for metastatic renal cancer and melanoma

  Cancer Journal from Scientific American. 1996;2(2):91-98.
  43

• 158.

  1996

  M.E. Reeves; S.A. Rosenberg; P. Hwu

  Transduction and differentiation of dendritic cells from human hematopoietic progenitor cells

  FASEB Journal. 1996;10(6):A1443.
  0

• 159.

  1995

  J. Treisman; P. Hwu; S. Minamoto; G.E. Shafer; R. Cowherd; R.A. Morgan; S.A. Rosenberg

  Interleukin-2-transduced lymphocytes grow in an autocrine fashion and remain responsive to antigen

  Blood. 1995;85(1):139-145.
  51

• 160.

  1995

  P. Hwu; J.C. Yang; R. Cowherd; J. Treisman; G.E. Shafer; Z. Eshhar; S.A. Rosenberg

  In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes

  Cancer Research. 1995;55(15):3369-3373.
  164

• 161.

  1994

  P. Hwu

  Gene therapy: progress and prospects.

  Contemporary urology. 1994;6(8):47-53.
  0

• 162.

  1994

  J. Treisman; P. Hwu; J.R. Yannelli; G.E. Shafer; R. Cowherd; D. Samid; S.A. Rosenberg

  Upregulation of tumor necrosis factor-α production by retrovirally transduced human tumor-infiltrating lymphocytes using trans-retinoic acid

  Cellular Immunology. 1994;156(2):448-457.
  11

• 163.

  1994

  P. Hwu; S.A. Rosenberg

  The genetic modification of T cells for cancer therapy: An overview of laboratory and clinical trials

  Cancer Detection and Prevention. 1994;18(1):43-50.
  30

• 164.

  1994

  P. Hwu

  What the future holds for gene therapy

  IM - Internal Medicine. 1994;15(2):39-42+45.
  0

• 165.

  1994

  P. Hwu; S.A. Rosenberg

  The use of gene-modified tumor-infiltrating lymphocytes for cancer therapy

  Annals of the New York Academy of Sciences. 1994;716:188-199.
  12

• 166.

  1993

  Stephen E. Karp; Alik Farber; Jonathan C. Salo; Patrick Hwu; Gitie Jaffe; Anthony L. Asher; Eitan Shiloni; Nicholas P. Restifo; James J. Mulé; Steven A. Rosenberg

  Cytokine Secretion by Genetically Modified Nonimmunogenic Murine Fibrosarcoma Tumor Inhibition by IL-2 but Not Tumor Necrosis Factor

  Journal of Immunology. 1993;150(3):896-908.
  62

• 167.

  1993

  P. Hwu; G.E. Shafer; J. Treisman; D.G. Schindler; G. Gross; R. Cowherd; S.A. Rosenberg; Z. Eshhar

  Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor γ chain

  Journal of Experimental Medicine. 1993;178(1):361-366.
  125

• 168.

  1993

  P. Hwu; J. Yannelli; M. Kriegler; W.F. Anderson; C. Perez; Y. Chiang; S. Schwarz; R. Cowherd; C. Delgado; et al.

  Functional and molecular characterization of tumor-infiltrating lymphocytes transduced with tumor necrosis factor-α cDNA for the gene therapy of cancer in humans

  Journal of Immunology. 1993;150(9):4104-4115.
  81

• 169.

  1993

  J.R. Yannelli; C. Hyatt; S. Johnson; P. Hwu; S.A. Rosenberg

  Characterization of human tumor cell lines transduced with the cDNA encoding either tumor necrosis factor α (TNF-a) or interleukin-2 (IL-2)

  Journal of Immunological Methods. 1993;161(1):77-90.
  28

• 170.

  1993

  S.A. Rosenberg; W.F. Anderson; M. Blaese; P. Hwu; J.R. Yannelli; J.C. Yang; S.L. Topalian; D.J. Schwartzentruber; J.S. Weber; S.E. Ettinghausen; et al.

  The development of gene therapy for the treatment of cancer

  Annals of Surgery. 1993;218(4):455-464.
  39

• 171.

  1992

  P. Hwu; S. Schwarz; M. Custer; C.A. Smith; J.J. Mule; S.A. Rosenberg

  Use of soluble recombinant TNF receptor to improve detection of TNF secretion in cultures of tumor infiltrating lymphocytes

  Journal of Immunological Methods. 1992;151(1-2):139-147.
  5

• 172.

  1992

  S.E. Karp; P. Hwu; A. Farber; N.P. Restifo; M. Kriegler; J.J. Mule; S.A. Rosenberg

  In vivo activity of tumor necrosis factor (TNF) mutants: Secretory but not membrane-bound TNF mediates the regression of retrovirally transduced murine tumor

  Journal of Immunology. 1992;149(6):2076-2081.
  14

• 173.

  1988

  Walla L. Dempsey; Patrick Hwu; Diane Haddock Russell; Page S. Morahan

  Bone marrow derived macrophages have polyamine and ectoenzyme phenotypes distinct from resident macrophages

  Life Sciences. 1988;42(20):2019-2027.
  0

• 174.

  1986

  H.A. Young; L. Varesio; P. Hwu

  Posttranscriptional control of human gamma interferon gene expression in transfected mouse fibroblasts.

  Molecular and cellular biology. 1986;6(6):2253-2256.
  0

• 175.

  1984

  W.L. Dempsey; P. Hwu; P.S. Morahan

  Ectoenzyme phenotype characterization of bone marrow derived macrophages (BMDM)

  Federation Proceedings. 1984;43(6):no. 113.
  0