Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Clinical utility of cytomegalovirus viral load in bronchoalveolar lavage in lung transplant recipients
Roy F. Chemaly; Belinda Yen-Lieberman; Jeffrey Chapman; Amy Reilly; B. Nebiyou Bekele; Steven M. Gordon; Gary W. Procop; Nabin Shrestha; Carlos M. Isada; Malcolm DeCamp; et al. (Profiled Author: Roy F Chemaly)
American Journal of Transplantation. 2005;5(3):544-548.Abstract
The utility of cytomegalovirus (CMV) viral load (VL) by quantitative hybrid capture assay (Q-HCA) was investigated in bronchoalveolar lavage (BAL) from lung transplant recipients and compared with BAL cultures and blood VL. Forty-three consecutive BAL samples from 27 lung transplant recipients were analyzed. All samples had shell vial (SV) cultures in addition to Q-HCA. Histopathology was done on all lung tissues, and immunohistochemistry (IMC) in those with positive CMV cultures. Fifteen (56%) lung transplant recipients had both positive BAL SV cultures and BAL VL. Five of 15 had CMV pneumonitis with a VL in BAL >500 000 copies/mL (mean: 1638 450). Ten patients without CMV pneumonitis had VL in BAL <500 000 copies/mL (mean 81 820, p = 0.002). High VL in BAL and blood invariably meant CMV pneumonitis, but 2 patients with CMV pneumonitis had high BAL VL but relatively low blood VL. Initial CMV seronegativity was associated with pneumonitis (4/5 vs. 1/10; p = 0.004) and higher BAL CMV VL (p = 0.03). High CMV BAL or blood VL did not correlate with acute rejection or development of bronchiolitis obliterans syndrome (BOS). High CMV VL in BAL in lung transplant recipients is strongly associated with CMV pneumonitis, and may be more predictive than peripheral blood viral load. Copyright © Blackwell Munksgaard 2005.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Roy F. Chemaly; Belinda Yen-Lieberman; Elias A. Castilla; Amy Reilly; Susana Arrigain; Carol Farver; Robin K. Avery; Steven M. Gordon; Gary W. ProcopJournal of Clinical Microbiology. 2004;42(5):2168-2172.
Miki Kasai; Susan M. Harrington; Andrea Francesconi; Vidmantas Petraitis; Ruta Petraitiene; Mara G. Beveridge; Tena Knudsen; Jeffery Milanovich; Margaret P. Cotton; et al.Journal of Clinical Microbiology. 2008;46(11):3690-3702.
Thomas Wolf; Tonio Oumeraci; Jens Gottlieb; Andreas Pich; Benedikt Brors; Roland Eils; Axel Haverich; Brigitte Schlegelberger; Tobias Welte; Marc Zapatka; et al.Transplantation. 2011;92(4):477-485.
Appears in this Document