Head and Neck Cancer

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Pelvic normal tissue contouring guidelines for radiation therapy: A radiation therapy oncology group consensus panel atlas

Hiram A. Gay; H. Joseph Barthold; Elizabeth O'Meara; Walter R. Bosch; Issam El Naqa; Rawan Al-Lozi; Seth A. Rosenthal; Colleen Lawton; W. Robert Lee; Howard Sandler; et al. (Profiled Author: Anuja Jhingran)

International Journal of Radiation Oncology Biology Physics. 2012;83(3):e353-e362.

Purpose: To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials. Methods and Materials: One male pelvis computed tomography (CT) data set and one female pelvis CT data set were shared via the Image-Guided Therapy QA Center. A total of 16 radiation oncologists participated. The following organs at risk were contoured in both CT sets: anus, anorectum, rectum (gastrointestinal and genitourinary definitions), bowel NOS (not otherwise specified), small bowel, large bowel, and proximal femurs. The following were contoured in the male set only: bladder, prostate, seminal vesicles, and penile bulb. The following were contoured in the female set only: uterus, cervix, and ovaries. A computer program used the binomial distribution to generate 95% group consensus contours. These contours and definitions were then reviewed by the group and modified. Results: The panel achieved consensus definitions for pelvic normal tissue contouring in RTOG trials with these standardized names: Rectum, AnoRectum, SmallBowel, Colon, BowelBag, Bladder, UteroCervix, Adnexa-R, Adnexa-L, Prostate, SeminalVesc, PenileBulb, Femur-R, and Femur-L. Two additional normal structures whose purpose is to serve as targets in anal and rectal cancer were defined: AnoRectumSig and Mesorectum. Detailed target volume contouring guidelines and images are discussed. Conclusions: Consensus guidelines for pelvic normal tissue contouring were reached and are available as a CT image atlas on the RTOG Web site. This will allow uniformity in defining normal tissues for clinical trials delivering pelvic radiation and will facilitate future normal tissue complication research. © 2012 Elsevier Inc. All rights reserved.

PMID: 22483697    

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