The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Judit Marsillach; Rebecca J. Richter; Jerry H. Kim; Richard C. Stevens; Michael J. MacCoss; Daniela Tomazela; Stephanie M. Suzuki; Lawrence M. Schopfer; Oksana Lockridge; Clement E. Furlong (Profiled Authors: Oksana Lockridge; Lawrence M Schopfer)
There are ongoing events where aircraft engine lubricant containing tricresyl phosphates (TCPs) contaminates aircraft cabins. Some individuals have experienced tremors or other neurological symptoms that may last for many months following exposures. Mass spectrometric (MS) protocols are being developed to determine the percentage of " biomarker proteins" that are modified by such exposures, specifically on active site serines. Both plasma butyrylcholinesterase (BChE) and red cell acylpeptide hydrolase (APH) are readily inhibited by 2-(ortho-cresyl)-4. H-1,3,2-benzodioxaphosphoran-2-one (CBDP) or phenyl saligenin cyclic phosphate (PSP) and have the potential to provide information about the level of exposure of an individual. We have developed immunomagnetic bead-based single-step purification protocols for both BChE and APH and have characterized the active site serine adducts of BChE by MS. © 2011 Elsevier Inc.
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Eugénie Carletti; Lawrence M. Schopfer; Jacques-Philippe Colletier; Marie-Thérèse Froment; Florian Nachon; Martin Weik; Oksana Lockridge; Patrick Masson
Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: Mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysisChemical Research in Toxicology 2011;24(6):797-808.
Lawrence M. Schopfer; Clement E. Furlong; Oksana LockridgeAnalytical Biochemistry 2010;404(1):64-74.
J. Eric Haux; Oksana Lockridge; John E. CasidaChemical Research in Toxicology 2002;15(12):1527-1533.
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