Scopus Publication Detail
The publication detail shows the title, authors (with indicators showing other profiled authors), information on the publishing organization, abstract and a link to the article in Scopus. This abstract is what is used to create the fingerprint of the publication.
Synthetic polymers improve vitrification outcomes of macaque ovarian tissue as assessed by histological integrity and the in vitro development of secondary follicles
Alison Y. Ting; Richard R. Yeoman; Maralee S. Lawson; Mary B. Zelinski (Profiled Author: Mary Zelinski)
Ovarian tissue cryopreservation is the only proven option for fertility preservation in female cancer patients who are prepubertal or require immediate treatment. However it remains unclear which cryopreservation protocol is best in cases where the tissue may contain cancerous cells, as these should be matured in vitro rather than autografted. This study evaluated different cryoprotectant exposure times and whether the addition of synthetic polymers (Supercool X-1000, Z-1000 and polyvinylpyrrolidone [PVP K-12]) to the vitrification solution is beneficial to tissue morphology, cellular proliferation and subsequent in vitro function of secondary follicles. Pieces of macaque (n=4) ovarian cortex were exposed to vitrification solution containing glycerol (25%, v/v) and ethylene glycol (25%, v/v) for 3 or 8min, without (V3, V8) or with (VP3, VP8) polymers (0.2% [v/v] X-1000, 0.4% Z-1000 and 0.2% PVP). Fresh and vitrified tissues were fixed for histology and phosphohistone H3 (PPH3) analysis, or used for secondary follicle isolation followed by encapsulated 3D culture. Five-week follicle survival and growth, as well as steroid hormones (estradiol [E
This section shows information related to the publication - computed using the fingerprint of the publication - including related publications, related experts with fingerprints representing significant amounts of overlap between their fingerprint and this publication. The red dots indicate whether those experts or terms appear within the publication, thereby showing potential and actual connections.
Alison Y. Ting; Richard R. Yeoman; Maralee S. Lawson; Mary B. ZelinskiHuman Reproduction. 2011;26(9):2461-2472.
Cecily V. Bishop; Michelle L. Sparman; Jessica E. Stanley; Alistair Bahar; Mary B. Zelinski; Richard L. StoufferAmerican Journal of Primatology. 2009;71(5):384-392.
Timothy M. Hazzard; Richard M. Rohan; Theodore A. Molskness; John W. Fanton; Robert J. D'Amato; Richard L. StoufferEndocrine. 2002;17(3):199-206.
Appears in this Document