Hengming Ke

UNCCH, School of Medicine, Biochemistry and Biophysics

Publications

• 1.

  2013

  Chimed Jansen; Huanchen Wang; Albert J. Kooistra; Chris De Graaf; Kristina M. Orrling; Hermann Tenor; Thomas Seebeck; David Bailey; Iwan J. P. De Esch; Hengming Ke; et al.

  Discovery of novel Trypanosoma brucei phosphodiesterase B1 inhibitors by virtual screening against the unliganded TbrPDEB1 crystal structure

  Journal of Medicinal Chemistry. 2013;56(5):2087-2096.

• 2.

  2012

  Fei Meng; Jing Hou; Yong-Xian Shao; Pei-Ying Wu; Manna Huang; Xinhai Zhu; Yonghong Cai; Zhe Li; Jie Xu; Peiqing Liu; et al.

  Structure-based discovery of highly selective phosphodiesterase-9A inhibitors and implications for inhibitor design

  Journal of Medicinal Chemistry. 2012;55(19):8549-8558.

• 3.

  2012

  Qinghui Yuan; Lin He; Hengming Ke

  A potential substrate binding conformation of β-lactams and insight into the broad spectrum of NDM-1 activity

  Antimicrobial Agents and Chemotherapy. 2012;56(10):5157-5163.

Journals

•  
  Publications
• Proceedings of the National Academy of Sciences of the United States of America
  15
• Journal of Biological Chemistry
  9
• Biochemistry
  7
• Journal of Molecular Biology
  7
• Structure
  5

Institutional Network

• Internal Organizations
  Shared Pub.
• Pathology and Laboratory Medicine
  2
• Radiation Oncology
  2
• Infectious Diseases
  1
• Lineberger Comprehensive Cancer Center – Administration and Program Leaders
  1
• Molecular Genetics and Microbiology
  1
• Pharmacy
  1

• External Organizations
  Shared Pub.
• Brookhaven National Laboratory
  14
• Harvard University
  13
• Sun Yat-Sen University
  10
• University of North Carolina School of Medicine
  10
• Harvard Medical School
  6
• Universität Bern
  5

Coauthor Network

• Internal Coauthors
  Shared Pub.
• Brian A Kuhlman
  2
• Michael D Topal
  2
• Yanping Zhang
  2
• Maria Elena Cardenas-Corona
  1
• Gary Matthew Cox
  1
• Joseph Barry Heitman
  1

• External Coauthors
  Shared Pub.
• Howard Robinson
  14
• William N Lipscomb
  13
• Yingdong Zhao
  7
• Sharron H Francis
  5
• Jiwen Cai
  5
• Thomas Seebeck
  5