Aziz Sancar

UNCCH, School of Medicine, Biochemistry and Biophysics

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Aziz Sancar

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Biochemistry and Biophysics
  
  

Help us refine your profile

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Nuri Ozturk; Sarah J. VanVickle-Chavez; Lakshmi Akileswaran; Russell N. Van Gelder; Aziz Sancar

  Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex

  Proceedings of the National Academy of Sciences of the United States of America. 2013;110(13):4980-4985.
  0

• 2.

  2013

  Jin Hyup Lee; Shobhan Gaddameedhi; Nuri Ozturk; Rui Ye; Aziz Sancar

  DNA damage-specific control of cell death by cryptochrome in p53-mutant ras-transformed cells

  Cancer Research. 2013;73(2):785-791.
  0

• 3.

  2012

  Laura A. Lindsey-Boltz; Joyce T. Reardon; Marc S. Wold; Aziz Sancar

  In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling

  Journal of Biological Chemistry. 2012;287(43):36123-36131.
  0

• 4.

  2012

  Shobhan Gaddameedhi; Joyce T. Reardon; Rui Ye; Nuri Ozturk; Aziz Sancar

  Effect of circadian clock mutations on DNA damage response in mammalian cells

  Cell Cycle. 2012;11(18):3481-3491.
  0

• 5.

  2012

  Michael G. Kemp; Aziz Sancar

  DNA excision repair: Where do all the dimers go?

  Cell Cycle. 2012;11(16):2997-3002.
  1

• 6.

  2012

  Michael G. Kemp; Joyce T. Reardon; Laura A. Lindsey-Boltz; Aziz Sancar

  Mechanism of release and fate of excised oligonucleotides during nucleotide excision repair

  Journal of Biological Chemistry. 2012;287(27):22889-22899.
  1

• 7.

  2012

  Dongping Zhong; Aziz Sancar; Alexei Stuchebrukhov

  Reply to Brettel and Byrdin: On the efficiency of DNA repair by photolyase

  Proceedings of the National Academy of Sciences of the United States of America. 2012;109(23):E1463.
  0

• 8.

  2012

  Zheyun Liu; Xunmin Guo; Chuang Tan; Jiang Li; Ya-Ting Kao; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Electron tunneling pathways and role of adenine in repair of cyclobutane pyrimidine dimer by DNA photolyase

  Journal of the American Chemical Society. 2012;134(19):8104-8114.
  3

• 9.

  2012

  Ajna S. Rivera; Nuri Ozturk; Bryony Fahey; David C. Plachetzki; Bernard M. Degnan; Aziz Sancar; Todd H. Oakley

  Blue-light-receptive cryptochrome is expressed in a sponge eye lacking neurons and opsin

  Journal of Experimental Biology. 2012;215(8):1278-1286.
  4

• 10.

  2012

  Christopher P. Selby; Aziz Sancar

  The second chromophore in drosophila photolyase/cryptochrome family photoreceptors

  Biochemistry. 2012;51(1):167-171.
  0

• 11.

  2011

  Shobhan Gaddameedhi; Christopher P. Selby; William K. Kaufmann; Robert C. Smart; Aziz Sancar

  Control of skin cancer by the circadian rhythm

  Proceedings of the National Academy of Sciences of the United States of America. 2011;108(46):18790-18795.
  10

• 12.

  2011

  Zheyun Liu; Chuang Tan; Xunmin Guo; Ya-Ting Kao; Jiang Li; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Dynamics and mechanism of cyclobutane pyrimidine dimer repair by DNA photolyase

  Proceedings of the National Academy of Sciences of the United States of America. 2011;108(36):14831-14836.
  16

• 13.

  2011

  Rui Ye; Christopher P. Selby; Nuri Ozturk; Yunus Annayev; Aziz Sancar

  Biochemical analysis of the canonical model for the mammalian circadian clock

  Journal of Biological Chemistry. 2011;286(29):25891-25902.
  10

• 14.

  2011

  Jin Hyup Lee; Aziz Sancar

  Regulation of apoptosis by the circadian clock through NF-κB signaling

  Proceedings of the National Academy of Sciences of the United States of America. 2011;108(29):12036-12041.
  11

• 15.

  2011

  Jin Hyup Lee; Aziz Sancar

  Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis

  Proceedings of the National Academy of Sciences of the United States of America. 2011;108(26):10668-10672.
  6

• 16.

  2011

  Michael G. Kemp; Laura A. Lindsey-Boltz; Aziz Sancar

  The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) are stimulated by bulky adduct-containing DNA

  Journal of Biological Chemistry. 2011;286(22):19237-19246.
  5

• 17.

  2011

  Laura A. Lindsey-Boltz; Aziz Sancar

  Tethering DNA damage checkpoint mediator proteins topoisomerase IIβ-binding protein 1 (TopBP1) and claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1)

  Journal of Biological Chemistry. 2011;286(22):19229-19236.
  9

• 18.

  2011

  Tae-Hong Kang; Joyce T. Reardon; Aziz Sancar

  Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein

  Nucleic Acids Research. 2011;39(8):3176-3187.
  10

• 19.

  2011

  Shobhan Gaddameedhi; Aziz Sancar

  Melanoma and DNA damage from a distance (farstander effect)

  Pigment Cell and Melanoma Research. 2011;24(1):3-4.
  1

• 20.

  2011

  Nuri Ozturk; Christopher P Selby; Yunus Annayev; Dongping Zhong; Aziz Sancar

  Reaction mechanism of Drosophila cryptochrome.

  Proceedings of the National Academy of Sciences of the United States of America. 2011;108(2):516-521.
  13

• 21.

  2011

  Nuri Ozturk; Christopher P. Selby; Yunus Annayev; Dongping Zhong; Aziz Sancar

  Reaction mechanism of Drosophila cryptochrome

  Proceedings of the National Academy of Sciences of the United States of America. 2011;108(2):528-533.
  2

• 22.

  2011

  Seçil Yilmaz; Aziz Sancar; Michael G. Kemp

  Multiple ATR-Chk1 pathway proteins preferentially associate with Checkpoint-Inducing DNA substrates

  PLoS ONE. 2011;6(7).
  3

• 23.

  2010

  Jiang Li; Zheyun Liu; Chuang Tan; Xunmin Guo; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Dynamics and mechanism of repair of ultraviolet-induced (6-4) photoproduct by photolyase

  Nature. 2010;466(7308):887-890.
  35

• 24.

  2010

  Jun-Hyuk Choi; Laura A. Lindsey-Boltz; Michael Kemp; Aaron C. Mason; Marc S. Wold; Aziz Sancar

  Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

  Proceedings of the National Academy of Sciences of the United States of America. 2010;107(31):13660-13665.
  29

• 25.

  2010

  Shobhan Gaddameedhi; Michael G. Kemp; Joyce T. Reardon; Janiel M. Shields; Stephanie L. Smith-Roe; William K. Kaufmann; Aziz Sancar

  Similar nucleotide excision repair capacity in melanocytes and melanoma cells

  Cancer Research. 2010;70(12):4922-4930.
  9

• 26.

  2010

  Aziz Sancar; Laura A. Lindsey-Boltz; Tae-Hong Kang; Joyce T. Reardon; Jin Hyup Lee; Nuri Ozturk

  Circadian clock control of the cellular response to DNA damage

  FEBS Letters. 2010;584(12):2618-2625.
  17

• 27.

  2010

  Michael G. Kemp; Zafer Akan; Seçil Yilmaz; Mary Grillo; Stephanie L. Smith-Roe; Tae-Hong Kang; Marila Cordeiro-Stone; William K. Kaufmann; Robert T. Abraham; Aziz Sancar; et al.

  Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress

  Journal of Biological Chemistry. 2010;285(22):16562-16571.
  25

• 28.

  2010

  Tae-Hong Kang; Laura A. Lindsey-Boltz; Joyce T. Reardon; Aziz Sancar

  Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase

  Proceedings of the National Academy of Sciences of the United States of America. 2010;107(11):4890-4895.
  30

• 29.

  2010

  Yiyong Liu; Yanan Fang; Hongbing Shao; Laura Lindsey-Boltz; Aziz Sancar; Paul Modrich

  Interactions of human mismatch repair proteins MutSα and MutLα with proteins of the ATR-Chk1 pathway

  Journal of Biological Chemistry. 2010;285(8):5974-5982.
  15

• 30.

  2010

  Chih-Wei Chang; Lijun Guo; Ya-Ting Kao; Jiang Li; Chuang Tan; Tanping Li; Chaitanya Saxena; Zheyun Liu; Lijuan Wang; Aziz Sancar; et al.

  Ultrafast solvation dynamics at binding and active sites of photolyases

  Proceedings of the National Academy of Sciences of the United States of America. 2010;107(7):2914-2919.
  23

• 31.

  2010

  Michael G. Kemp; Aaron C. Mason; Aura Carreira; Joyce T. Reardon; Stuart J. Haring; Gloria E. O. Borgstahl; Stephen C. Kowalczykowski; Aziz Sancar; Marc S. Wold

  An alternative form of replication protein A expressed in normal human tissues supports DNA repair

  Journal of Biological Chemistry. 2010;285(7):4788-4797.
  9

• 32.

  2009

  Laura A. Lindsey-Boltz; Özdemirhan Serçin; Jun-Hyuk Choi; Aziz Sancar

  Reconstitution of human claspin-mediated phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) checkpoint kinase

  Journal of Biological Chemistry. 2009;284(48):33107-33114.
  17

• 33.

  2009

  Michael Kemp; Aziz Sancar

  DNA Distress: Just Ring 9-1-1

  Current Biology. 2009;19(17):R733-R734.
  3

• 34.

  2009

  Nuri Ozturk; Christopher P. Selby; Sang-Hun Song; Rui Ye; Chuang Tan; Ya-Ting Kao; Dongping Zhong; Aziz Sancar

  Comparative photochemistry of animal type 1 and type 4 cryptochromes

  Biochemistry. 2009;48(36):8585-8593.
  9

• 35.

  2009

  Li Li; Joana Perdigao; Anthony E. Pegg; Yanbin Lao; Stephen S. Hecht; Bruce R. Lindgren; Joyce T. Reardon; Aziz Sancar; Elizabeth V. Wattenberg; Lisa A. Peterson

  The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines

  Chemical Research in Toxicology. 2009;22(8):1464-1472.
  7

• 36.

  2009

  Tae-Hong Kang; Aziz Sancar

  Circadian regulation of DNA excision repair: Implications for chrono-chemotherapy

  Cell Cycle. 2009;8(11):1665-1667.
  22

• 37.

  2009

  Lata Balakrishnan; Patrick D. Brandt; Laura A. Lindsey-Boltz; Aziz Sancar; Robert A. Bambara

  Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex

  Journal of Biological Chemistry. 2009;284(22):15158-15172.
  20

• 38.

  2009

  Jun-Hyuk Choi; Aziz Sancar; Laura A. Lindsey-Boltz

  The human ATR-mediated DNA damage checkpoint in a reconstituted system

  Methods. 2009;48(1):3-7.
  12

• 39.

  2009

  Tae-Hong Kang; Joyce T. Reardon; Michael Kemp; Aziz Sancar

  Orcadian oscillation of nucleotide excision repair in mammalian brain

  Proceedings of the National Academy of Sciences of the United States of America. 2009;106(8):2864-2867.
  43

• 40.

  2009

  Aziz Sancar; Nuri Ozturk; Jin Hyup Lee; Shobhan Gaddameedhi

  Loss of cryptochrome reduces cancer risk in p53 mutant mice

  Proceedings of the National Academy of Sciences of the United States of America. 2009;106(8):2841-2846.
  32

• 41.

  2009

  Jun-Hyuk Choi; Laura A. Lindsey-Boltz; Aziz Sancar

  Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA

  Nucleic Acids Research. 2009;37(5):1501-1509.
  16

• 42.

  2008

  Aziz Sancar

  Structure and function of photolyase and in vivo enzymology: 50th Anniversary

  Journal of Biological Chemistry. 2008;283(47):32153-32157.
  45

• 43.

  2008

  Ya-Ting Kao; Chaitanya Saxena; Ting-Fang He; Lijun Guo; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Ultrafast dynamics of flavins in five redox states

  Journal of the American Chemical Society. 2008;130(39):13132-13139.
  40

• 44.

  2008

  Nuri Öztürk; Ya-Ting Kao; Christopher P. Selby; I. Halil Kavakli; Carrie L. Partch; Dongping Zhong; Aziz Sancar

  Purification and characterization of a type III photolyase from Caulobacter crescentus

  Biochemistry. 2008;47(39):10255-10261.
  9

• 45.

  2008

  Jonathan P. Wisor; Ravi K. Pasumarthi; Dmitry Gerashchenko; Carol L. Thompson; Sayan Pathak; Aziz Sancar; Paul Franken; Ed S. Lein; Thomas S. Kilduff

  Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains (Journal of Neuroscience (July 9, 2008) (7193-7201))

  Journal of Neuroscience. 2008;28(31):7929.
  0

• 46.

  2008

  Jonathan P. Wisor; Ravi K. Pasumarthi; Dmitry Gerashchenko; Carol L. Thompson; Sayan Pathak; Aziz Sancar; Paul Franken; Ed S. Lein; Thomas S. Kilduff

  Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains

  Journal of Neuroscience. 2008;28(28):7193-7201.
  19

• 47.

  2008

  Katherine S. Lovejoy; Ryan C. Todd; Shuzhong Zhang; Michael S. McCormick; J. Alejandro D'Aquino; Joyce T. Reardon; Aziz Sancar; Kathleen M. Giacomini; Stephen J. Lippard

  cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects

  Proceedings of the National Academy of Sciences of the United States of America. 2008;105(26):8902-8907.
  77

• 48.

  2008

  Ya-Ting Kao; Chuang Tan; Sang-Hun Song; Nuri Öztürk; Jiang Li; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Ultrafast dynamics and anionic active states of the flavin cofactor in cryptochrome and photolyase

  Journal of the American Chemical Society. 2008;130(24):7695-7701.
  41

• 49.

  2008

  Nuri Öztürk; Sang-Hun Song; Christopher P. Selby; Aziz Sancar

  Animal Type 1 cryptochromes: Analysis of the redox state of the flavin cofactor by site-directed mutagenesis

  Journal of Biological Chemistry. 2008;283(6):3256-3263.
  38

• 50.

  2008

  Aziz Sancar

  The intelligent clock and the Rube Goldberg clock

  Nature Structural and Molecular Biology. 2008;15(1):23-24.
  7

• 51.

  2007

  Kevin J. Kesseler; William K. Kaufmann; Joyce T. Reardon; Timothy C. Elston; Aziz Sancar

  A mathematical model for human nucleotide excision repair: Damage recognition by random order assembly and kinetic proofreading

  Journal of Theoretical Biology. 2007;249(2):361-375.
  13

• 52.

  2007

  Laura A. Lindsey-Boltz; Aziz Sancar

  RNA polymerase: The most specific damage recognition protein in cellular responses to DNA damage?

  Proceedings of the National Academy of Sciences of the United States of America. 2007;104(33):13213-13214.
  16

• 53.

  2007

  Jun-Hyuk Choi; Laura A. Lindsey-Boltz; Aziz Sancar

  Reconstitution of a human ATR-mediated checkpoint response to damaged DNA

  Proceedings of the National Academy of Sciences of the United States of America. 2007;104(33):13301-13306.
  34

• 54.

  2007

  Sang-Hun Song; Nuri Öztürk; Tracy R. Denaro; N. Özlem Arat; Ya-Ting Kao; Haisun Zhu; Dongping Zhong; Steven M. Reppert; Aziz Sancar

  Formation and function of flavin anion radical in cryptochrome 1 blue-light photoreceptor of monarch butterfly

  Journal of Biological Chemistry. 2007;282(24):17608-17612.
  44

• 55.

  2007

  Ya-Ting Kao; Chaitanya Saxena; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Femtochemistry in enzyme catalysis: DNA photolyase

  Cell Biochemistry and Biophysics. 2007;48(1):32-44.
  17

• 56.

  2007

  Keziban Ünsal-Kaçmaz; Paul D. Chastain; Ping-Ping Qu; Parviz Minoo; Marila Cordeiro-Stone; Aziz Sancar; William K. Kaufmann

  The human Tim/Tipin complex coordinates an intra-S checkpoint response to UV that slows replication fork displacement

  Molecular and Cellular Biology. 2007;27(8):3131-3142.
  97

• 57.

  2007

  Timothy P. Heffernan; Keziban Ünsal-Kaçmaz; Alexandra N. Heinloth; Dennis A. Simpson; Richard S. Paules; Aziz Sancar; Marila Cordeiro-Stone; William K. Kaufmann

  Cdc7-Dbf4 and the human S checkpoint response to UVC

  Journal of Biological Chemistry. 2007;282(13):9458-9468.
  28

• 58.

  2007

  Olga Sokolova; Christine Cecala; Anand Gopal; Frank Cortazar; Carla McDowell-Buchanan; Aziz Sancar; Yvonne M. Gindt; Johannes P. M. Schelvis

  Resonance Raman spectroscopic investigation of the light-harvesting chromophore in Escherichia coli photolyase and Vibrio cholerae cryptochrome-1

  Biochemistry. 2007;46(12):3673-3681.
  7

• 59.

  2007

  N. Öztürk; S.-H. Song; S. Özgür; C.P. Selby; L. Morrison; C. Partch; D. Zhong; A. Sancar

  Structure and function of animal cryptochromes

  Cold Spring Harbor Symposia on Quantitative Biology. 2007;72:119-131.
  19

• 60.

  2006

  Christopher P. Selby; Aziz Sancar

  A cryptochrome/photolyase class of enzymes with single-stranded DNA-specific photolyase activity

  Proceedings of the National Academy of Sciences of the United States of America. 2006;103(47):17696-17700.
  96

• 61.

  2006

  Reade B. Roberts; Carol L. Thompson; Daekee Lee; Richard W. Mankinen; Aziz Sancar; David W. Threadgill

  Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice

  Journal of Circadian Rhythms. 2006;4.
  1

• 62.

  2006

  Sezgin Özgür; Aziz Sancar

  Analysis of autophosphorylating kinase activities of arabidopsis and human cryptochromes

  Biochemistry. 2006;45(44):13369-13374.
  22

• 63.

  2006

  Wensheng Wang; Laura A. Lindsey-Boltz; Aziz Sancar; Robert A. Bambara

  Mechanism of stimulation of human DNA ligase I by the Rad9-Rad1-Hus1 checkpoint complex

  Journal of Biological Chemistry. 2006;281(30):20865-20872.
  27

• 64.

  2006

  Carrie L. Partch; Katherine F. Shields; Carol L. Thompson; Christopher P. Selby; Aziz Sancar

  Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5

  Proceedings of the National Academy of Sciences of the United States of America. 2006;103(27):10467-10472.
  31

• 65.

  2006

  Joyce T. Reardon; Yuan Cheng; Aziz Sancar

  Repair of DNA-protein cross-links in mammalian cells

  Cell Cycle. 2006;5(13):1366-1370.
  14

• 66.

  2006

  Joyce T. Reardon; Aziz Sancar

  Repair of DNA-polypeptide crosslinks by human excision nuclease

  Proceedings of the National Academy of Sciences of the United States of America. 2006;103(11):4056-4061.
  36

• 67.

  2006

  Joyce T. Reardon; Aziz Sancar

  Purification and Characterization of Escherichia coli and Human Nucleotide Excision Repair Enzyme Systems

  Methods in Enzymology. 2006;408:189-213.
  22

• 68.

  2006

  Guochun Jiang; Aziz Sancar

  Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences

  Molecular and Cellular Biology. 2006;26(1):39-49.
  32

• 69.

  2006

  Gwendolyn B. Sancar; Aziz Sancar

  Purification and Characterization of DNA Photolyases

  Methods in Enzymology. 2006;408:121-156.
  6

• 70.

  2005

  Ya-Ting Kao; Chaitanya Saxena; Lijuan Wang; Aziz Sancar; Dongping Zhong

  Direct observation of thymine dimer repair in DNA by photolyase

  Proceedings of the National Academy of Sciences of the United States of America. 2005;102(45):16128-16132.
  105

• 71.

  2005

  Carrie L. Partch; Aziz Sancar

  Photochemistry and photobiology of cryptochrome blue-light photopigments: The search for a photocycle

  Photochemistry and Photobiology. 2005;81(6):1291-1304.
  56

• 72.

  2005

  Gülnihal Kulaksiz; Joyce T. Reardon; Aziz Sancar

  Xeroderma pigmentosum complementation group E protein (XPE/DDB2): Purification of various complexes of XPE and analyses of their damaged DNA binding and putative DNA repair properties

  Molecular and Cellular Biology. 2005;25(22):9784-9792.
  26

• 73.

  2005

  Maria C. Derosa; Aziz Sancar; Jacqueline K. Barton

  Electrically monitoring DNA repair by photolyase

  Proceedings of the National Academy of Sciences of the United States of America. 2005;102(31):10788-10792.
  31

• 74.

  2005

  Michele A. Gauger; Aziz Sancar

  Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer

  Cancer Research. 2005;65(15):6828-6834.
  66

• 75.

  2005

  Chaitanya Saxena; Haiyu Wang; I. Halil Kavakli; Aziz Sancar; Dongping Zhong

  Ultrafast dynamics of resonance energy transfer in cryptochrome

  Journal of the American Chemical Society. 2005;127(22):7984-7985.
  21

• 76.

  2005

  Keziban Ünsal-Kaçmaz; Thomas E. Mullen; William K. Kaufmann; Aziz Sancar

  Coupling of human circadian and cell cycles by the timeless protein

  Molecular and Cellular Biology. 2005;25(8):3109-3116.
  117

• 77.

  2005

  Carrie L. Partch; Michael W. Clarkson; Sezgin Özgür; Andrew L. Lee; Aziz Sancar

  Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor

  Biochemistry. 2005;44(10):3795-3805.
  56

• 78.

  2005

  Stephanie Q. Hutsell; Aziz Sancar

  Nucleotide excision repair, oxidative damage, DNA sequence polymorphisms, and cancer treatment

  Clinical Cancer Research. 2005;11(4):1355-1357.
  4

• 79.

  2005

  Haiyu Wang; Chaitanya Saxena; Donghui Quan; Aziz Sancar; Dongping Zhong

  Femtosecond dynamics of flavin cofactor in DNA photolyase: Radical reduction, local Solvation, and charge recombination

  Journal of Physical Chemistry B. 2005;109(4):1329-1333.
  22

• 80.

  2005

  Carrie L. Partch; Aziz Sancar

  Cryptochromes and circadian photoreception in animals

  Methods in Enzymology. 2005;393:726-745.
  20

• 81.

  2005

  Joyce T. Reardon; Aziz Sancar

  Nucleotide Excision Repair

  Progress in Nucleic Acid Research and Molecular Biology. 2005;79:183-235.
  110

• 82.

  2004

  I. Halil Kavakli; Aziz Sancar

  Analysis of the role of intraprotein electron transfer in photoreactivation by DNA photolyase in vivo

  Biochemistry. 2004;43(48):15103-15110.
  36

• 83.

  2004

  Carol L. Thompson; Christopher P. Selby; Russell N. Van Gelder; William S. Blaner; Janet Lee; Loredana Quadro; Katherine Lai; Max E. Gottesman; Aziz Sancar

  Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice

  Journal of Biological Rhythms. 2004;19(6):504-517.
  12

• 84.

  2004

  Wensheng Wang; Patrick Brandt; Marie L. Rossi; Laura Lindsey-Boltz; Vladimir Podust; Ellen Fanning; Alix Sancar; Robert A. Bambara

  The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1

  Proceedings of the National Academy of Sciences of the United States of America. 2004;101(48):16762-16767.
  57

• 85.

  2004

  Chaitanya Saxena; Aziz Sancar; Dongping Zhong

  Femtosecond dynamics of DNA photolyase: Energy transfer of antenna initiation and electron transfer of cofactor reduction

  Journal of Physical Chemistry B. 2004;108(46):18026-18033.
  44

• 86.

  2004

  Funda Sar; Laura A. Lindsey-Boltz; Deepa Subramanian; Deborah L. Croteau; Stephanie Q. Hutsell; Jack D. Griffith; Aziz Sancar

  Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures

  Journal of Biological Chemistry. 2004;279(38):39289-39295.
  45

• 87.

  2004

  Aziz Sancar

  Regulation of the mammalian circadian clock by cryptochrome

  Journal of Biological Chemistry. 2004;279(33):34079-34082.
  56

• 88.

  2004

  Carol L. Thompson; Christopher P. Selby; Carrie L. Partch; David T. Plante; Randy J. Thresher; Francisco Araujo; Aziz Sancar

  Further evidence for the role of cryptochromes in retinohypothalamic photoreception/phototransduction

  Molecular Brain Research. 2004;122(2):158-166.
  18

• 89.

  2004

  Keziban Ünsal-Kaçmaz; Aziz Sancar

  Quaternary Structure of ATR and Effects of ATRIP and Replication Protein A on Its DNA Binding and Kinase Activities

  Molecular and Cellular Biology. 2004;24(3):1292-1300.
  60

• 90.

  2004

  Joyce T. Reardon; Aziz Sancar

  Thermodynamic cooperativity and kinetic proofreading in DNA damage recognition and repair

  Cell Cycle. 2004;3(2):141-144.
  26

• 91.

  2004

  Aziz Sancar; Laura A. Lindsey-Boltz; Keziban Ünsal-Kaçmaz; Stuart Linn

  Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

  Annual Review of Biochemistry. 2004;73:39-85.
  1149

• 92.

  2004

  Laura A. Lindsey-Boltz; Eric M. Wauson; Lee M. Graves; Aziz Sancar

  The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD

  Nucleic Acids Research. 2004;32(15):4524-4530.
  10

• 93.

  2004

  Aziz Sancar; Joyce T. Reardon

  Nucleotide excision repair in E. coli and man

  Advances in Protein Chemistry. 2004;69:43-71.
  32

• 94.

  2004

  Aziz Sancar

  Photolyase and cryptochrome blue-light photoreceptors

  Advances in Protein Chemistry. 2004;69:73-100.
  29

• 95.

  2003

  Joyce T. Reardon; Aziz Sancar

  Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease

  Genes and Development. 2003;17(20):2539-2551.
  83

• 96.

  2003

  Erin N. Worthington; I. Halil Kavakli; Gloria Berrocal-Tito; Bruce E. Bondo; Aziz Sancar

  Purification and characterization of three members of the photolyase/cryptochrome family blue-light photoreceptors from vibrio cholerae

  Journal of Biological Chemistry. 2003;278(40):39143-39154.
  54

• 97.

  2003

  Carol L. Thompson; Catherine Bowes Rickman; Steven J. Shaw; Jessica N. Ebright; Una Kelly; Aziz Sancar; Dennis W. Rickman

  Expression of the blue-light receptor cryptochrome in the human retina

  Investigative Ophthalmology and Visual Science. 2003;44(10):4515-4521.
  30

• 98.

  2003

  Ögrünç, Müge; Sancar, Aziz

  Identification and characterization of human MUS81-MMS4 structure-specific endonuclease

  Journal of Biological Chemistry. 2003;278(24):21715-21720.
  39

• 99.

  2003

  Dong Wang; Ryujiro Hara; Gitanjali Singh; Aziz Sancar; Stephen J. Lippard

  Nucleotide excision repair from site-specifically platinum-modified nucleosomes

  Biochemistry. 2003;42(22):6747-6753.
  48

• 100.

  2003

  Ryujiro Hara; Aziz Sancar

  Effect of damage type on stimulation of human excision nuclease by SWI/SNF chromatin remodeling factor

  Molecular and Cellular Biology. 2003;23(12):4121-4125.
  38

• 101.

  2003

  Aziz Sancar

  Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors

  Chemical Reviews. 2003;103(6):2203-2237.
  471

• 102.

  2003

  Sezgin Özgür; Aziz Sancar

  Purification and properties of human blue-light photoreceptor cryptochrome 2

  Biochemistry. 2003;42(10):2926-2932.
  29

• 103.

  2003

  Vladimir P. Bermudez; Laura A. Lindsey-Boltz; Anthony J. Cesare; Yoshimasa Maniwa; Jack D. Griffith; Jerard Hurwitz; Aziz Sancar

  Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

  Proceedings of the National Academy of Sciences of the United States of America. 2003;100(4):1633-1638.
  177

• 104.

  2003

  Russell N. Van Gelder; Aziz Sancar; Sehgal; Lee

  Cryptochromes and inner retinal non-visual irradiance detection

  Novartis Foundation Symposium. 2003;253:31-51.
  6

• 105.

  2003

  C.P. Selby; Aziz Sancar

  Characterization of Transcription-Repair Coupling Factors in E. Coli and Humans

  Methods in Enzymology. 2003;371:300-324.
  4

• 106.

  2002

  Jonathan P. Wisor; Bruce F. O'Hara; Akira Terao; Chris P. Selby; Thomas S. Kilduff; Aziz Sancar; Dale M. Edgar; Paul Franken

  A role of cryptochromes in sleep regulation

  BMC Neuroscience. 2002;3.
  103

• 107.

  2002

  Carol L. Thompson; Aziz Sancar

  Photolyase/cryptochrome blue-light photoreceptors use photon energy to repair DNA and reset the circadian clock

  Oncogene. 2002;21(58 REV. ISS. 8):9043-9056.
  37

• 108.

  2002

  Ibrahim Halil Kavakli; Aziz Sancar

  Circadian photoreception in humans and mice.

  Mol Interv. 2002;2(8):484-492.
  22

• 109.

  2002

  Ryujiro Hara; Aziz Sancar

  The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle

  Molecular and Cellular Biology. 2002;22(19):6779-6787.
  85

• 110.

  2002

  Russell N. Van Gelder; Therese M. Gibler; Daniel Tu; Kris Embry; Christopher P. Selby; Carol L. Thompson; Aziz Sancar

  Pleiotropic effects of cryptoChromes 1 and 2 on free-running and light-entrained murine circadian rhythms

  Journal of Neurogenetics. 2002;16(3):181-203.
  27

• 111.

  2002

  Nicolas Cermakian; Matthew P Pando; Carol L Thompson; Anna B Pinchak; Christopher P Selby; Laura Gutierrez; Dan E Wells; Gregory M Cahill; Aziz Sancar; Paolo Sassone-Corsi

  Light induction of a vertebrate clock gene involves signaling through blue-light receptors and MAP kinases

  Current Biology. 2002;12(10):844-848.
  61

• 112.

  2002

  Keziban Ünsal-Kaçmaz; Alexander M. Makhov; Jack D. Griffith; Aziz Sancar

  Preferential binding of ATR protein to UV-damaged DNA

  Proceedings of the National Academy of Sciences of the United States of America. 2002;99(10):6673-6678.
  101

• 113.

  2002

  Jack D. Griffith; Laura A. Lindsey-Boltz; Aziz Sancar

  Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy

  Journal of Biological Chemistry. 2002;277(18):15233-15236.
  75

• 114.

  2002

  Mitsuo Wakasugi; Aki Kawashima; Hiroshi Morioka; Stuart Linn; Aziz Sancar; Toshio Mori; Osamu Nikaido; Tsukasa Matsunaga

  DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair

  Journal of Biological Chemistry. 2002;277(3):1637-1640.
  123

• 115.

  2002

  Joyce T. Reardon; Aziz Sancar

  Molecular anatomy of the human excision nuclease assembled at sites of DNA damage

  Molecular and Cellular Biology. 2002;22(16):5938-5945.
  53

• 116.

  2001

  Carol L. Thompson; William S. Blaner; Russell N. Van Gelder; Katherine Lai; Loredana Quadro; Vittorio Colantuoni; Max E. Gottesman; Aziz Sancar

  Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice

  Proceedings of the National Academy of Sciences of the United States of America. 2001;98(20):11708-11713.
  50

• 117.

  2001

  Laura A. Lindsey-Boltz; Vladimir P. Bermudez; Jerard Hurwitz; Aziz Sancar

  Purification and characterization of human DNA damage checkpoint Rad complexes

  Proceedings of the National Academy of Sciences of the United States of America. 2001;98(20):11236-11241.
  127

• 118.

  2001

  Mark E. Branum; Joyce T. Reardon; Aziz Sancar

  DNA repair excision nuclease attacks undamaged DNA: A potential source of spontaneous mutations

  Journal of Biological Chemistry. 2001;276(27):25421-25426.
  56

• 119.

  2001

  J.W. George; E.P. Salazar; M.P.G. Vreeswijk; J.E. Lamerdin; J.T. Reardon; M.Z. Zdzienicka; A. Sancar; S. Kadkhodayan; R.S. Tebbs; L.H.F. Mullenders; et al.

  Restoration of nucleotide excision repair in a helicase-deficient XPD mutant from intragenic suppression by a trichothiodystrophy mutation

  Molecular and Cellular Biology. 2001;21(21):7355-7365.
  5

• 120.

  2000

  Christopher P. Selby; Carol Thompson; Therese M. Schmitz; Russell N. Van Gelder; Aziz Sancar

  Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice

  Proceedings of the National Academy of Sciences of the United States of America. 2000;97(26):14697-14702.
  121

• 121.

  2000

  Shinya Shibutani; Joyce T. Reardon; Naomi Suzuki; Azis Sancar

  Excision of tamoxifen-DNA adducts by the human nucleotide excision repair system

  Cancer Research. 2000;60(10):2607-2610.
  34

• 122.

  2000

  David Mu; Tadayoshi Bessho; Lubomir V. Nechev; David J. Chen; Thomas M. Harris; John E. Hearst; Aziz Sancar

  DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts

  Molecular and Cellular Biology. 2000;20(7):2446-2454.
  97

• 123.

  2000

  Tadayoshi Bessho; Aziz Sancar

  Human DNA damage checkpoint protein hRAD9 is a 3' to 5' exonuclease

  Journal of Biological Chemistry. 2000;275(11):7451-7454.
  56

• 124.

  2000

  A. Sancar; C. Thompson; R.J. Thresher; F. Araujo; J. Mo; S. Ozgur; E. Vagas; L. Dawut; C.P. Selby

  Photolyase/cryptochrome family blue-light photoreceptors use light energy to repair DNA or set the circadian clock

  Cold Spring Harbor Symposia on Quantitative Biology. 2000;65:157-171.
  8

• 125.

  2000

  R. Hara; J. Mo; A. Sancar

  DNA damage in the nucleosome core is refractory to repair by human excision nuclease

  Molecular and Cellular Biology. 2000;20(24):9173-9181.
  87

• 126.

  2000

  A. Sancar

  Cryptochrome: The second photoactive pigment in the eye and its role in circadian photoreception

  Annual Review of Biochemistry. 2000;69:31-67.
  152

• 127.

  1999

  Christopher W. M. Kay; Richard Feicht; Kristina Schulz; Peter Sadewater; Aziz Sancar; Adelbert Bacher; Klaus Möbius; Gerald Richter; Stefan Weber

  EPR, ENDOR, and TRIPLE resonance spectroscopy on the neutral flavin radical in Escherichia coli DNA photolyase

  Biochemistry. 1999;38(51):16740-16748.
  52

• 128.

  1999

  Claude Petit; Aziz Sancar

  From DNA photolyases to photoreceptors regulating biological clocks

  Medecine/Sciences. 1999;15(12):1411-1418.
  4

• 129.

  1999

  Martha Hotz Vitaterna; Christopher P. Selby; Takeshi Todo; Hitoshi Niwa; Carol Thompson; Ethan M. Fruechte; Kenichi Hitomi; Randy J. Thresher; Tomoko Ishikawa; Junichi Miyazaki; et al.

  Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2

  Proceedings of the National Academy of Sciences of the United States of America. 1999;96(21):12114-12119.
  326

• 130.

  1999

  Ryujiro Hara; Christopher P. Selby; Mingyi Liu; David H. Price; Aziz Sancar

  Human transcription release factor 2 dissociates RNA polymerases I and II stalled at a cyclobutane thymine dimer

  Journal of Biological Chemistry. 1999;274(35):24779-24786.
  35

• 131.

  1999

  Yasuhide Miyamoto; Aziz Sancar

  Circadian regulation of cryptochrome genes in the mouse

  Molecular Brain Research. 1999;71(2):238-243.
  55

• 132.

  1999

  Joyce T. Reardon; Alexandra Vaisman; Stephen G. Chaney; Aziz Sancar

  Efficient nucleotide excision repair of cisplatin, oxaliplatin, and bis- acetoammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts

  Cancer Research. 1999;59(16):3968-3971.
  174

• 133.

  1999

  Mitsuo Wakasugi; Aziz Sancar

  Order of assembly of human DNA repair excision nuclease

  Journal of Biological Chemistry. 1999;274(26):18759-18768.
  148

• 134.

  1999

  Yvonne M. Gindt; Esther Vollenbroek; Kristi Westphal; Heather Sackett; Aziz Sancar; Gerald T. Babcock

  Origin of the transient electron paramagnetic resonance signals in DNA photolyase

  Biochemistry. 1999;38(13):3857-3866.
  60

• 135.

  1999

  A. Sancar

  Excision repair invades the territory of mismatch repair

  Nature Genetics. 1999;21(3):247-249.
  19

• 136.

  1999

  Christopher P. Selby; Aziz Sancar

  A third member of the photolyase/blue-light photoreceptor family in Drosophila: A putative circadian photoreceptor

  Photochemistry and Photobiology. 1999;69(1):105-107.
  24

• 137.

  1999

  Claude Petit; Aziz Sancar

  Nucleotide excision repair: From E. coli to man

  Biochimie. 1999;81(1-2):15-25.
  129

• 138.

  1998

  Randy J. Thresher; Martha Hotz Vitaterna; Yasuhide Miyamoto; Aleksey Kazantsev; David S. Hsu; Claude Petit; Christopher P. Selby; Lale Dawut; Oliver Smithies; Joseph S. Takahashi; et al.

  Role of mouse cryptochrome blue-light photoreceptor in circadian photoresponses

  Science. 1998;282(5393):1490-1494.
  223

• 139.

  1998

  Mitsuo Wakasugi; Aziz Sancar

  Assembly, subunit composition, and footprint of human DNA repair excision nuclease

  Proceedings of the National Academy of Sciences of the United States of America. 1998;95(12):6669-6674.
  106

• 140.

  1998

  Yasuhide Miyamoto; Aziz Sancar

  Vitamin B₂-based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals

  Proceedings of the National Academy of Sciences of the United States of America. 1998;95(11):6097-6102.
  277

• 141.

  1998

  Aleksey Kazantsev; Sharon K. Bullock; Aziz Sancar; Marila Cordeiro-Stone

  Generation and characterization of an immortal cell line of xeroderma pigmentosum group E

  Mutation Research - DNA Repair. 1998;407(1):55-65.
  2

• 142.

  1998

  S.G. Khan; H.L. Levy; R. Legerski; E. Quackenbush; J.T. Reardon; S. Emmert; A. Sancar; L. Li; T.D. Schneider; J.E. Cleaver; et al.

  Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia

  Journal of Investigative Dermatology. 1998;111(5):791-796.
  39

• 143.

  1998

  M. Ogrunc; D.F. Becker; S.W. Ragsdale; A. Sancar

  Nucleotide excision repair in the third kingdom

  Journal of Bacteriology. 1998;180(21):5796-5798.
  26

• 144.

  1997

  Xiaodong Zhao; Jianquan Liu; David S. Hsu; Shaying Zhao; John-Stephen Taylor; Aziz Sancar

  Reaction mechanism of (6-4) photolyase

  Journal of Biological Chemistry. 1997;272(51):32580-32590.
  89

• 145.

  1997

  Tadayoshi Bessho; David Mu; Aziz Sancar

  Initiation of DNA interstrand cross-link repair in humans: The nucleotide excision repair system makes dual incisions 5' to the cross- linked base and removes a 22- to 28-nucleotide-long damage-free strand

  Molecular and Cellular Biology. 1997;17(12):6822-6830.
  96

• 146.

  1997

  David Mu; Mitsuo Wakasugi; David S. Hsu; Aziz Sancar

  Characterization of reaction intermediates of human excision repair nuclease

  Journal of Biological Chemistry. 1997;272(46):28971-28979.
  121

• 147.

  1997

  Shaying Zhao; Aziz Sancar

  Human Blue-light Photoreceptor hCRY2 Specifically Interacts with Protein Serine/Threonine Phosphatase 5 and Modulates Its Activity

  Photochemistry and Photobiology. 1997;66(5):727-731.
  69

• 148.

  1997

  Christopher P. Selby; Aziz Sancar

  Cockayne syndrome group B protein enhances elongation by RNA polymerase II

  Proceedings of the National Academy of Sciences of the United States of America. 1997;94(21):11205-11209.
  161

• 149.

  1997

  Joyce T. Reardon; Tadayoshi Bessho; Hsiang Chuan Kung; Philip H. Bolton; Aziz Sancar

  In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients

  Proceedings of the National Academy of Sciences of the United States of America. 1997;94(17):9463-9468.
  252

• 150.

  1997

  Mitsuo Wakasugi; Joyce T. Reardon; Aziz Sancar

  The Non-catalytic function of XPG protein during dual incision in human nucleotide excision repair

  Journal of Biological Chemistry. 1997;272(25):16030-16034.
  89

• 151.

  1997

  Boris Perelman; Naomi Dafni; Tova Naiman; Dalia Eli; Miri Yaakov; Teresa L. Yang Feng; Srish Sinha; Günther Weber; Shideh Khodaei; Aziz Sancar; et al.

  Molecular cloning of a novel human gene encoding a 63-kDa protein and its sublocalization within the 11q13 locus

  Genomics. 1997;41(3):397-405.
  16

• 152.

  1997

  Joyce T. Reardon; Larry H. Thompson; Aziz Sancar

  Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity

  Nucleic Acids Research. 1997;25(5):1015-1021.
  18

• 153.

  1997

  David Mu; Mihray Tursun; Derek R. Duckett; James T. Drummond; Paul Modrich; Aziz Sancar

  Recognition and repair of compound DNA lesions (base damage and mismatch) by human mismatch repair and excision repair systems

  Molecular and Cellular Biology. 1997;17(2):760-769.
  145

• 154.

  1997

  D. Mu; A. Sancar

  DNA excision repair assays.

  Progress in nucleic acid research and molecular biology. 1997;56:63-81.
  6

• 155.

  1997

  Christopher P. Selby; Ronny Drapkin; Danny Reinberg; Aziz Sancar

  RNA polymerase II stalled at a thymine dimer: Footprint and effect on excision repair

  Nucleic Acids Research. 1997;25(4):787-793.
  99

• 156.

  1997

  David Mu; Aziz Sancar

  Model for XPC-independent transcription-coupled repair of pyrimidine dimers in humans

  Journal of Biological Chemistry. 1997;272(12):7570-7573.
  63

• 157.

  1997

  Christopher P. Selby; Aziz Sancar

  Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II

  Journal of Biological Chemistry. 1997;272(3):1885-1890.
  150

• 158.

  1997

  Tadayoshi Bessho; Aziz Sancar; Larry H. Thompson; Michael P. Thelen

  Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex

  Journal of Biological Chemistry. 1997;272(6):3833-3837.
  128

• 159.

  1997

  Thomas Langenbacher; Xiaodong Zhao; Gero Bieser; Paul F. Heelis; Aziz Sancar; Maria Elisabeth Michel-Beyerle

  Substrate and temperature dependence of DNA photolyase repair activity examined with ultrafast spectroscopy

  Journal of the American Chemical Society. 1997;119(43):10532-10536.
  53

• 160.

  1997

  S.L. McCutchen-Maloney; M. Hwang; T. Bessho; A. Sancar; M.P. Thelen

  Characterization of the XPF endonuclease complex

  FASEB Journal. 1997;11(9):A1371.
  0

• 161.

  1996

  Stephen G. Chaney; Aziz Sancar

  DNA repair: Enzymatic mechanisms and relevance to drug response

  Journal of the National Cancer Institute. 1996;88(19):1346-1360.
  173

• 162.

  1996

  Joyce T. Reardon; Hui Ge; Emma Gibbs; Aziz Sancar; Jerard Hurwitz; Zhen-Qiang Pan

  Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH

  Proceedings of the National Academy of Sciences of the United States of America. 1996;93(13):6482-6487.
  86

• 163.

  1996

  Derek R. Duckett; James T. Drummond; Alastair I. H. Murchie; Joyce T. Reardon; Aziz Sancar; David M. J. Lilley; Paul Modrich

  Humnan MutSα recognizes damaged DNA base pairs containing O⁶-methylguanine, O⁴-methylthymine, or the cisplatin-d(GpG) adduct

  Proceedings of the National Academy of Sciences of the United States of America. 1996;93(13):6443-6447.
  296

• 164.

  1996

  Sang-Tae Kim; Khushbeer Malhotra; Haruko Ryo; Aziz Sancar; Takeshi Todo

  Purification and characterization of Drosophila melanogaster photolyase

  Mutation Research - DNA Repair. 1996;363(2):97-104.
  22

• 165.

  1996

  Aleksey Kazantsev; David Mu; Anne F. Nichols; Xiaodong Zhao; Stuart Linn; Aziz Sancar

  Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system

  Proceedings of the National Academy of Sciences of the United States of America. 1996;93(10):5014-5018.
  59

• 166.

  1996

  David Mu; David S. Hsu; Aziz Sancar

  Reaction mechanism of human DNA repair excision nuclease

  Journal of Biological Chemistry. 1996;271(14):8285-8294.
  270

• 167.

  1996

  Kim Sang-Tae; K. Malhotra; J.S. Taylor; A. Sancar

  Purification and partial characterization of (6-4) photoproduct DNA photolyase from Xenopus laevis

  Photochemistry and Photobiology. 1996;63(3):292-295.
  34

• 168.

  1996

  David S. Hsu; Xiaodong Zhao; Shaying Zhao; Aleksey Kazantsev; Rui-Ping Wang; Takeshi Todo; Ying-Fei Wei; Aziz Sancar

  Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins

  Biochemistry. 1996;35(44):13871-13877.
  183

• 169.

  1996

  A. Sancar

  No 'end of history' for photolyases

  Science. 1996;272(5258):48-49.
  77

• 170.

  1996

  Aziz Sancar

  DNA excision repair

  Annual Review of Biochemistry. 1996;65:43-81.
  778

• 171.

  1996

  Deborah B. Zamble; David Mu; Joyce T. Reardon; Aziz Sancar; Stephen J. Lippard

  Repair of cisplatin-DNA adducts by the mammalian excision nuclease

  Biochemistry. 1996;35(31):10004-10013.
  228

• 172.

  1996

  J.T. Reardon; H. Ge; E. Gibbs; A. Sancar; J. Hurwitz; Z.-Q. Pan

  Erratum: Isolation and characterization of two human transcription factor IIH (TFIIH)-related complexes: ERCC2/CAK and TFIIH (Proceedings of the National Academy of Sciences of the United States of America (June 25, 1996) 93:13 (6482-6487))

  Proceedings of the National Academy of Sciences of the United States of America. 1996;93(19):10538.
  0

• 173.

  1996

  Joyce T. Reardon; David Mu; Aziz Sancar

  Overproduction, purification, and characterization of the XPC subunit of the human DNA repair excision nuclease

  Journal of Biological Chemistry. 1996;271(32):19451-19456.
  81

• 174.

  1996

  A. Sancar

  Molecular mechanism of excision repair in humans

  FASEB Journal. 1996;10(6):A959.
  0

• 175.

  1996

  Kerry W. Brookman; Jane E. Lamerdin; Michael P. Thelen; Mona Hwang; Joyce T. Reardon; Aziz Sancar; Zi-Qiang Zhou; Christi A. Walter; Christopher N. Parris; et al.

  ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs

  Molecular and Cellular Biology. 1996;16(11):6553-6562.
  78

• 176.

  1996

  Tsukasa Matsunaga; Chi-Hyun Park; Tadayoshi Bessho; David Mu; Aziz Sancar

  Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease

  Journal of Biological Chemistry. 1996;271(19):11047-11050.
  125

• 177.

  1995

  T. Matsunaga; D. Mu; C.-H. Park; J.T. Reardon; A. Sancar

  Human DNA repair excision nuclease. Analysis of the roles of the subunits involved in dual incisions by using anti-XPG and anti-ERCC1 antibodies

  Journal of Biological Chemistry. 1995;270(35):20862-20869.
  135

• 178.

  1995

  Aziz Sancar

  Excision repair in mammalian cells

  Journal of Biological Chemistry. 1995;270(27):15915-15918.
  129

• 179.

  1995

  David Mu; Elisabeth Bertrand-burggraf; Juch-chin Huang; Robert P.P. Fuchs; Aziz Sancar

  Human and E.Coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct

  Nucleic Acids Research. 1995;23(3):540.
  0

• 180.

  1995

  Kim Sang-Tae; A. Sancar

  Photorepair of nonadjacent pyrimidine dimers by DNA photolyase

  Photochemistry and Photobiology. 1995;61(2):171-174.
  19

• 181.

  1995

  Aziz Sancar

  DNA repair in humans

  Annual Review of Genetics. 1995;29:69-105.
  159

• 182.

  1995

  Aziz Sancar

  Putative blue-light photoreceptors from arabidopsis thaliana and sinapis alba with a high degree of sequence homology to DNA photolyase contain the two photolyase cofactors but lack DNA repair activity

  Biochemistry®. 1995;34(20):6892-6899.
  162

• 183.

  1995

  Z.-Q. Pan; C.-H. Park; A.A. Amin; J. Hurwitz; A. Sancar

  Phosphorylated and unphosphorylated forms of human single-stranded DNA- binding protein are equally active in simian virus 40 DNA replication and in nucleotide excision repair

  Proceedings of the National Academy of Sciences of the United States of America. 1995;92(10):4636-4640.
  57

• 184.

  1995

  C.-H. Park; T. Bessho; T. Matsunaga; A. Sancar

  Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease

  Journal of Biological Chemistry. 1995;270(39):22657-22660.
  90

• 185.

  1995

  Z.-Q. Pan; J.T. Reardon; L. Li; H. Flores-Rozas; R. Legerski; A. Sancar; J. Hurwitz

  Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21

  Journal of Biological Chemistry. 1995;270(37):22008-22016.
  135

• 186.

  1995

  S.-T. Kim; P.F. Heelis; A. Sancar

  Role of tryptophans in substrate binding and catalysis by DNA photolyase

  Methods in Enzymology. 1995;258:319-343.
  16

• 187.

  1995

  H.-W. Park; S.-T. Kim; A. Sancar; J. Deisenhofer

  Crystal structure of DNA photolyase from Escherichia coli

  Science. 1995;268(5219):1866-1894.
  338

• 188.

  1995

  Z. Ozer; J.T. Reardon; D.S. Hsu; K. Malhotra; A. Sancar

  The other function of DNA photolyase: Stimulation of excision repair of chemical damage to DNA

  Biochemistry. 1995;34(49):15886-15889.
  30

• 189.

  1995

  D. Mu; C.-H. Park; T. Matsunaga; D.S. Hsu; J.T. Reardon; A. Sancar

  Reconstitution of human DNA repair excision nuclease in a highly defined system

  Journal of Biological Chemistry. 1995;270(6):2415-2418.
  316

• 190.

  1995

  D. Mu; E. Bertrand-Burggraf; J.-C. Huang; R.P.P. Fuchs; A. Sancar

  Erratum: Human and E. Coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct (Nucleic Acids Research (1994) 22 (4869-4871))

  Nucleic Acids Research. 1995;23(3):540.
  1

• 191.

  1995

  D.S. Hsu; S.-T. Kim; Q. Sun; A. Sancar

  Structure and function of the UvrB protein

  Journal of Biological Chemistry. 1995;270(14):8319-8327.
  55

• 192.

  1995

  C.-H. Park; D. Mu; J.T. Reardon; A. Sancar

  The general transcription-repair factor TFIIH is recruited to the excision repair complex by the XPA protein independent of the TFIIE transcription factor

  Journal of Biological Chemistry. 1995;270(9):4896-4902.
  139

• 193.

  1995

  C.P. Selby; A. Sancar

  Structure and function of transcription-repair coupling factor. II. Catalytic properties

  Journal of Biological Chemistry. 1995;270(9):4890-4895.
  64

• 194.

  1995

  C.P. Selby; A. Sancar

  Structure and function of transcription-repair coupling factor. I. Structural domains and binding properties

  Journal of Biological Chemistry. 1995;270(9):4882-4889.
  79

• 195.

  1995

  A. Kazantsev; A. Sancar; M.L. Smith; I.-T. Chen; A.J. Fornace Jr.

  Does the p53 up-regulated Gadd45 protein have a role in excision repair?

  Science. 1995;270(5238):1003-1006.
  30

• 196.

  1994

  Juch-Chin Huang; David S. Hsu; Aleksey Kazantsev; Aziz Sancar

  Substrate spectrum of human excinuclease: Repair of abasic sites, methylated bases, mismatches, and bulky adducts

  Proceedings of the National Academy of Sciences of the United States of America. 1994;91(25):12213-12217.
  155

• 197.

  1994

  Juch-Chin Huang; Deborah B. Zamble; Joyce T. Reardon; Stephen J. Lippard; Aziz Sancar

  HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease

  Proceedings of the National Academy of Sciences of the United States of America. 1994;91(22):10394-10398.
  239

• 198.

  1994

  Christopher P. Selby; Aziz Sancar

  Mechanisms of transcription-repair coupling and mutation frequency decline

  Microbiological Reviews. 1994;58(3):317-329.
  88

• 199.

  1994

  Juch-Chin Huang; Aziz Sancar

  Determination of minimum substrate size for human excinuclease

  Journal of Biological Chemistry. 1994;269(29):19034-19040.
  46

• 200.

  1994

  Larry H. Thompson; Kerry W. Brookman; Christine A. Weber; Edmund P. Salazar; Joyce T. Reardon; Aziz Sancar; Zuoming Deng; Michael J. Siciliano

  Molecular cloning of the human nucleotide-excision-repair gene ERCC4

  Proceedings of the National Academy of Sciences of the United States of America. 1994;91(15):6855-6859.
  28

• 201.

  1994

  Chi-Hyun Park; Aziz Sancar

  Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins

  Proceedings of the National Academy of Sciences of the United States of America. 1994;91(11):5017-5021.
  122

• 202.

  1994

  Ronny Drapkin; Joyce T. Reardon; Athar Ansari; Juch-Chin Huang; Leigh Zawel; KyuJeong Ahn; Aziz Sancar; Danny Reinberg

  Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

  Nature. 1994;368(6473):769-772.
  294

• 203.

  1994

  Sang-Tae Kim; Martin Volk; Gerhard Rousseau; Paul F. Heelis; Aziz Sancar; Maria-Elisabeth Michel-Beyerle

  Laser flash photolysis on an intermediate in the repair of pyrimidine dimers by DNA photolyase

  Journal of the American Chemical Society. 1994;116(7):3115-3116.
  21

• 204.

  1994

  Sang-Tae Kim; Khushbeer Malhotra; Colin A. Smith; John-Stephen Taylor; Aziz Sancar

  Characterization of (6-4) photoproduct DNA photolyase

  Journal of Biological Chemistry. 1994;269(11):8535-8540.
  99

• 205.

  1994

  Aziz Sancar

  Structure and function of DNA photolyase

  Biochemistry. 1994;33(1):2-9.
  405

• 206.

  1994

  Ronny Drapkin; Aziz Sancar; Danny Reinberg

  Where transcription meets repair

  Cell. 1994;77(1):9-12.
  100

• 207.

  1994

  David S. Hsu; Masayuki Takahashi; Emmanuelle Delagoutte; Elisabeth Bertrand-Burggraf; Yuh-Hwa Wang; Bengt Norden; Robert P. P. Fuchs; Jack Griffith; Aziz Sancar

  Flow linear dichroism and electron microscopic analysis of protein-DNA complexes of a mutant UvrB protein that binds to but cannot kink DNA

  Journal of Molecular Biology. 1994;241(5):645-650.
  7

• 208.

  1994

  Khushbeer Malhotra; Sang-Tae Kim; Aziz Sancar

  Characterization of a medium wavelength type DNA photolyase: Purification and properties of photolyase from Bacillus firmus

  Biochemistry. 1994;33(29):8712-8718.
  29

• 209.

  1994

  D. Mu; E. Bertrand-Burggraf; J.-C. Huang; B.P.P. Fuchs; A. Sancar

  Human and E.coli excinucleases are affected differently by the sequence context of acetylaminofluorene-guanine adduct

  Nucleic Acids Research. 1994;22(23):4869-4871.
  29

• 210.

  1994

  A. Sancar

  Mechanisms of DNA excision repair

  Science. 1994;266(5193):1954-1956.
  396

• 211.

  1994

  Srinivas S. Sastry; H. Peter Spielmann; Quan Scott Hoang; A. Meleah Phillips; Aziz Sancar; John E. Hearst

  Erratum: Laser-induced protein-DN A cross-links via psoralen furanside monoadducts (Biochemistry (1993) 32 21 (5526-5537))

  Biochemistry. 1994;33(6):1616.
  1

• 212.

  1993

  Sang-Tae Kim; Aziz Sancar; Craig Essenmacher; Gerald T. Babcock

  Time-resolved EPR studies with DNA photolyase: Excited-state FADH⁰ abstracts an electron from Trp-306 to generate FADH^-, the catalytically active form of the cofactor

  Proceedings of the National Academy of Sciences of the United States of America. 1993;90(17):8023-8027.
  74

• 213.

  1993

  A. Sancar; M.S. Tang

  Nucleotide excision repair.

  Photochemistry and Photobiology. 1993;57(5):905-921.
  118

• 214.

  1993

  S.T. Kim; A. Sancar

  Photochemistry, photophysics, and mechanism of pyrimidine dimer repair by DNA photolyase.

  Photochemistry and Photobiology. 1993;57(5):895-904.
  89

• 215.

  1993

  J.T. Reardon; L.H. Thompson; A. Sancar

  Excision repair in man and the molecular basis of Xeroderma pigmentosum syndrome

  Cold Spring Harbor Symposia on Quantitative Biology. 1993;58:605-617.
  41

• 216.

  1993

  C.P. Selby; A. Sancar

  Molecular mechanism of transcription-repair coupling

  Science. 1993;259(5104):53-58.
  322

• 217.

  1993

  Ywan Feng Li; S.-T. Kim; A. Sancar

  Evidence for lack of DNA photoreactivating enzyme in humans

  Proceedings of the National Academy of Sciences of the United States of America. 1993;90(10):4389-4393.
  63

• 218.

  1993

  D.L. Svoboda; C.A. Smith; J.-S.A. Taylor; A. Sancar

  Effect of sequence, adduct type, and opposing lesions on the binding and repair of ultraviolet photodamage by DNA photolyase and (A)BC excinuclease

  Journal of Biological Chemistry. 1993;268(14):10694-10700.
  50

• 219.

  1993

  H.-W. Park; A. Sancar; J. Deisenhofer

  Crystallization and preliminary crystallographic analysis of Escherichia coli DNA photolyase

  Journal of Molecular Biology. 1993;231(4):1122-1125.
  7

• 220.

  1993

  S.-T. Kim; K. Malhotra; C.A. Smith; J.-S. Taylor; A. Sancar

  DNA photolyase repairs the trans-syn cyclobutane thymine dimer

  Biochemistry. 1993;32(28):7065-7068.
  17

• 221.

  1993

  Srinivas S. Sastry; H. Peter Spielmann; Quan Scott Hoang; A. Meleah Phillips; Aziz Sancar; John E. Hearst

  Laser-induced protein-DNA cross-links via psoralen furanside monoadducts

  Biochemistry. 1993;32(21):5526-5538.
  25

• 222.

  1993

  D.L. Svoboda; J.-S. Taylor; J.E. Hearst; A. Sancar

  DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes

  Journal of Biological Chemistry. 1993;268(3):1931-1936.
  55

• 223.

  1993

  C.P. Selby; A. Sancar

  Transcription-repair coupling and mutation frequency decline

  Journal of Bacteriology. 1993;175(23):7509-7514.
  30

• 224.

  1993

  C.-H. Park; A. Sancar

  Reconstitution of mammalian excision repair activity with mutant cell-free extracts and XPAC and ERCC1 proteins expressed in Escherichia coli

  Nucleic Acids Research. 1993;21(22):5110-5116.
  13

• 225.

  1993

  J.T. Reardon; A.F. Nichols; S. Keeney; C.A. Smith; J.-S. Taylor; S. Linn; A. Sancar

  Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli damage recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[t,s]T, T[6-4]T, and T[Dewar]T

  Journal of Biological Chemistry. 1993;268(28):21301-21308.
  133

• 226.

  1993

  P.F. Heelis; S.-T. Kim; T. Okamura; A. Sancar

  The photo repair of pyrimidine dimers by DNA photolyase and model systems

  Journal of Photochemistry and Photobiology B: Biology. 1993;17(3):219-228.
  55

• 227.

  1993

  A. Sancar; J.E. Hearst

  Molecular matchmakers

  Science. 1993;259(5100):1415-1421.
  99

• 228.

  1993

  Craig Essenmacher; Sang-Tae Kim; Michael Atamian; Gerald T. Babcock; Aziz Sancar

  Tryptophan radical formation in DNA photolyase: Electron-spin polarization arising from photoexcitation of a doublet ground state

  Journal of the American Chemical Society. 1993;115(4):1602-1603.
  20

• 229.

  1992

  Jing-Jer Lin; Aziz Sancar

  Active site of (A)BC excinuclease: I. Evidence for 5′ incision by UvrC through a catalytic site involving Asp³⁹⁹, Asp⁴³⁸, Asp⁴⁶⁶, and His⁵³⁸ residues

  Journal of Biological Chemistry. 1992;267(25):17688-17692.
  70

• 230.

  1992

  A.F. Nichols; A. Sancar

  Purification of PCNA as a nucleotide excision repair protein

  Nucleic Acids Research. 1992;20(13):3549.
  0

• 231.

  1992

  Sibghat-Ullah; A. Sancar

  In vitro characterization of repair synthesis initiated by T4 endonuclease V on a synthetic DNA substrate.

  Indian Journal of Biochemistry and Biophysics. 1992;29(3):227-230.
  0

• 232.

  1992

  K. Malhotra; M. Baer; Ywan Feng Li; G.B. Sancar; A. Sancar

  Identification of chromophore binding domains of yeast DNA photolyase

  Journal of Biological Chemistry. 1992;267(5):2909-2914.
  8

• 233.

  1992

  J.-J. Lin; A.M. Phillips; J.E. Hearst; A. Sancar

  Active site of (A)BC excinuclease. II. Binding, bending, and catalysis mutants of UvrB reveal a direct role in 3' and an indirect role in 5' incision

  Journal of Biological Chemistry. 1992;267(25):17693-17700.
  60

• 234.

  1992

  J.-J. Lin; A. Sancar

  (A)BC excinuclease: The Escherichia coli nucleotide excision repair enzyme

  Molecular Microbiology. 1992;6(16):2219-2224.
  48

• 235.

  1992

  K. Malhotra; S.-T. Kim; C. Walsh; A. Sancar

  Roles of FAD and 8-hydroxy-5-deazaflavin chromophores in photoreactivation by Anacystis nidulans DNA photolyase

  Journal of Biological Chemistry. 1992;267(22):15406-15411.
  33

• 236.

  1992

  P.F. Heelis; A. Sancar; T. Okamura

  Excited quartet states in DNA photolyase

  Journal of Photochemistry and Photobiology B: Biology. 1992;16(3-4):387-390.
  4

• 237.

  1992

  Sang-Tae Kim; Paul F. Heelis; Aziz Sancar

  Energy transfer (deazaflavin → FADH₂) and electon transfer (FADH₂ → T<>T) kinetics in Anacystis nidulans photolyase

  Biochemistry. 1992;31(45):11244-11248.
  51

• 238.

  1992

  S.-T. Kim; Ywan Feng Li; A. Sancar

  The third chromophore of DNA photolyase: Trp-277 of Escherichia coli DNA photolyase repairs thymine dimers by direct electron transfer

  Proceedings of the National Academy of Sciences of the United States of America. 1992;89(3):900-904.
  32

• 239.

  1992

  J.-C. Huang; D.L. Svoboda; J.T. Reardon; A. Sancar

  Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer

  Proceedings of the National Academy of Sciences of the United States of America. 1992;89(8):3664-3668.
  219

• 240.

  1992

  D.K. Orren; C.P. Selby; J.E. Hearst; A. Sancar

  Post-incision steps of nucleotide excision repair in Escherichia coli

  Journal of Biological Chemistry. 1992;267(2):780-788.
  65

• 241.

  1992

  A.F. Nichols; A. Sancar

  Purification of PCNA as a nucleotide excision repair protein

  Nucleic Acids Research. 1992;20(10):2441-2446.
  111

• 242.

  1992

  A.F. Nichols; W.J. Schmidt; S.G. Chaney; A. Sancar

  Limitations of the in vitro repair synthesis assay for probing the role of DNA repair in platinum resistance

  Chemico-Biological Interactions. 1992;81(3):223-231.
  2

• 243.

  1992

  A.F. Nichols; A. Sancar

  Erratum: Purification of PCNA as a nucleotide excision repair protein (Nucleic Acids Research (1992) 20 (2441-2446))

  Nucleic Acids Research. 1992;20(13):3549+E2441-E2446.
  27

• 244.

  1992

  Q. Shi; R. Thresher; A. Sancar; J. Griffith

  Electron microscopic study of (A)BC excinuclease DNA is sharply bent in the UvrB-DNA complex

  Journal of Molecular Biology. 1992;226(2):425-432.
  53

• 245.

  1992

  P.F. Heelis; D.J. Deeble; S.-T. Kim; A. Sancar

  Splitting of cis-syn cyclobutane thymine-thymine dimers by radiolysis and its relevance to enzymatic photoreactivation

  International Journal of Radiation Biology. 1992;62(2):137-143.
  27

• 246.

  1991

  Tadashi Okamura; Aziz Sancar; Paul F. Heelis; Tadhg P. Begley; Yoshinori Hirata; Noboru Mataga

  Picosecond laser photolysis studies on the photorepair of pyrimidine dimers by DNA photolyase. 1. Laser photolysis of photolyase-2-deoxyuridine dinucleotide photodimer complex

  Journal of the American Chemical Society. 1991;113(8):3143-3145.
  46

• 247.

  1991

  C.P. Selby; A. Sancar

  Gene- and strand-specific repair in vitro: Partial purification of a transcription-repair coupling factor

  Proceedings of the National Academy of Sciences of the United States of America. 1991;88(18):8232-8236.
  36

• 248.

  1991

  G.M. Myles; A. Sancar

  Isolation and characterization of functional domains of UvrA

  Biochemistry. 1991;30(16):3834-3840.
  14

• 249.

  1991

  C.P. Selby; A. Sancar

  Noncovalent drug-DNA binding interactions that inhibit and stimulate (A)BC excinuclease

  Biochemistry. 1991;30(16):3841-3849.
  16

• 250.

  1991

  Ywan Feng Li; Paul F. Heelis; Aziz Sancar

  Active site of DNA photolyase: Tryptophan-306 is the intrinsic hydrogen atom donor essential for flavin radical photoreduction and DNA repair in vitro

  Biochemistry. 1991;30(25):6322-6329.
  87

• 251.

  1991

  Y.F. Li; A. Sancar

  Cloning, sequencing, expression and characterization of DNA photolyase from Salmonella typhimurium

  Nucleic Acids Research. 1991;19(18):4885-4890.
  13

• 252.

  1991

  J.T. Reardon; P. Spielmann; J.-C. Huang; S. Sastry; A. Sancar; J.E. Hearst

  Removal of psoralen monoadducts and crosslinks by human cell free extracts

  Nucleic Acids Research. 1991;19(17):4623-4629.
  23

• 253.

  1991

  G.M. Myles; J.E. Hearst; A. Sancar

  Site-specific mutagenesis of conserved residues within Walker A and B sequences of Escherichia coli UvrA protein

  Biochemistry. 1991;30(16):3824-3834.
  34

• 254.

  1991

  J.C. Jones; W. Zhen; E. Reed; R.J. Parker; A. Sancar; V.A. Bohr

  Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells

  Journal of Biological Chemistry. 1991;266(11):7101-7107.
  86

• 255.

  1991

  S. Cheng; A. Sancar; J.E. Hearst

  RecA-dependent incision of psoralen-crosslinked DNA by (A)BC excinuclease

  Nucleic Acids Research. 1991;19(3):657-6663.
  47

• 256.

  1991

  J.-J. Lin; A. Sancar

  The C-terminal half of UvrC protein is sufficient to reconstitute (A)BC excinuclease

  Proceedings of the National Academy of Sciences of the United States of America. 1991;88(15):6824-6828.
  12

• 257.

  1991

  E. Bertrand-Burggraf; C.P. Selby; J.E. Hearst; A. Sancar

  Identification of the different intermediates in the interaction of (A)BC excinuclease with its substrates by DNase I footprinting on two uniquely modified oligonucleotides

  Journal of Molecular Biology. 1991;219(1):27-36.
  33

• 258.

  1991

  S.-T. Kim; P.F. Heelis; T. Okamura; Y. Hirata; N. Mataga; A. Sancar

  Determination of rates and yields of interchromophore (folate → flavin) energy transfer and intermolecular (flavin → DNA) electron transfer in Escherichia coli photolyase by time-resolved fluorescence and absorption spectroscopy

  Biochemistry. 1991;30(47):11262-11270.
  73

• 259.

  1991

  C.P. Selby; E.M. Witkin; A. Sancar

  Escherichia coli mfd mutant deficient in 'mutation frequency decline' lacks strand-specific repair: In vitro complementation with purified coupling factor

  Proceedings of the National Academy of Sciences of the United States of America. 1991;88(24):11574-11578.
  79

• 260.

  1990

  C.P. Selby; A. Sancar

  Structure and function of the (A)BC excinuclease of Escherichia coli

  Mutation Research. 1990;236(2-3):203-211.
  23

• 261.

  1990

  Gillian Payne; Aziz Sancar

  Absolute action spectrum of E-FADH₂ and E-FADH₂-MTHF forms of Escherichia coli DNA photolyase

  Biochemistry. 1990;29(33):7715-7727.
  48

• 262.

  1990

  Jimmy D. Page; Intisar Husain; Aziz Sancar; Stephen G. Chaney

  Effect of the diaminocyclohexane carrier ligand on platinum adduct formation, repair, and lethality

  Biochemistry. 1990;29(4):1016-1024.
  74

• 263.

  1990

  S. Hamm-Alvarez; A. Sancar; K.V. Rajagopalan

  The folate cofactor of Escherichia coli DNA photolyase acts catalytically

  Journal of Biological Chemistry. 1990;265(30):18656-18662.
  10

• 264.

  1990

  D.K. Orren; A. Sancar

  Formation and enzymatic properties of the UvrB·DNA complex

  Journal of Biological Chemistry. 1990;265(26):15796-15803.
  57

• 265.

  1990

  C.P. Selby; A. Sancar

  Mechanisms of caffeine inhibition of DNA repair in E. coli.

  Progress in clinical and biological research. 1990;340 A:179-193.
  6

• 266.

  1990

  Sibghat-Ullah; A. Sancar; J.E. Hearst

  The repair patch of E. coli (A)BC excinuclease

  Nucleic Acids Research. 1990;18(17):5051-5053.
  15

• 267.

  1990

  S.F. Hamm-Alvarez; A. Sancar; K.V. Rajagopalan

  The presence and distribution of reduced folates in Escherichia coli dihydrofolate reductase mutants

  Journal of Biological Chemistry. 1990;265(17):9850-9856.
  7

• 268.

  1990

  C.P. Selby; A. Sancar

  Molecular mechanisms of DNA repair inhibition by caffeine

  Proceedings of the National Academy of Sciences of the United States of America. 1990;87(9):3522-3525.
  77

• 269.

  1990

  Sibghat-Ullah; A. Sancar

  Substrate overlap and functional competition between human nucleotide excision repair and Escherichia coli photolyase and (A)BC excision nuclease

  Biochemistry. 1990;29(24):5711-5718.
  3

• 270.

  1990

  J.-J. Lin; A. Sancar

  Reconstitution of nucleotide excision nuclease with UvrA and UvrB proteins from Escherichia coli and UvrC protein from Bacillus subtilis

  Journal of Biological Chemistry. 1990;265(34):21337-21341.
  14

• 271.

  1990

  C.P. Selby; A. Sancar

  Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro

  Journal of Biological Chemistry. 1990;265(34):21330-21336.
  75

• 272.

  1989

  A. Kiener; I. Husain; A. Sancar; C. Walsh

  Purification and properties of Methanobacterium thermoautotrophicum DNA photolyase.

  Journal of Biological Chemistry. 1989;264(23):13880-13887.
  38

• 273.

  1989

  Sigghat-Ullah; I. Husain; W. Carlton; A. Sancar

  Human nucleotide excision repair in vitro: Repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract

  Nucleic Acids Research. 1989;17(12):4471-4484.
  54

• 274.

  1989

  Gary M. Myles; Aziz Sancar

  DNA repair

  Chemical Research in Toxicology. 1989;2(4):197-226.
  24

• 275.

  1989

  S. Hamm-Alvarez; A. Sancar; K.V. Rajagopalan

  Role of enzyme-bound 5,10-methenyltetrahydropteroylpolyglutamate in catalysis by Escherichia coli DNA photolyase

  Journal of Biological Chemistry. 1989;264(16):9649-9656.
  18

• 276.

  1989

  D.K. Orren; A. Sancar

  The (A)BC excinuclease of Escherichia coli has only the UvrB and UvrC subunits in the incision complex

  Proceedings of the National Academy of Sciences of the United States of America. 1989;86(14):5237-5241.
  77

• 277.

  1989

  D.C. Thomas; D.S. Okumoto; A. Sancar; V.A. Bohr

  Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells

  Journal of Biological Chemistry. 1989;264(30):18005-18010.
  22

• 278.

  1989

  N.S. Payne; A. Sancar

  The LexA protein does not bind specifically to the two SOS box-like sequences immediately 5' to the phr gene

  Mutation Research. 1989;218(3):207-210.
  3

• 279.

  1989

  Jing-Jer Lin; Aziz Sancar

  A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycols from DNA

  Biochemistry. 1989;28(20):7979-7984.
  88

• 280.

  1989

  S. Navaratnam; G.M. Myles; R.W. Strange; A. Sancar

  Evidence from extended X-ray absorption fine structure and site-specific mutagenesis for zinc fingers in UvrA protein of Escherichia coli

  Journal of Biological Chemistry. 1989;264(27):16067-16071.
  32

• 281.

  1989

  J.M. Voigt; B. Van Houten; A. Sancar; M.D. Topal

  Repair of O⁶-methylguanine by ABC excinuclease of Escherichia coli in vitro

  Journal of Biological Chemistry. 1989;264(9):5172-5176.
  40

• 282.

  1989

  Tadashi Okamura; Aziz Sancar; Paul F. Heelis; Yoshinori Hirata; Noboru Mataga

  Doublet-quartet intersystem crossing of flavin radical in DNA photolyase

  Journal of the American Chemical Society. 1989;111(15):5967-5969.
  15

• 283.

  1988

  I. Husain; W.L. Carrier; J.D. Regan; A. Sancar

  Photoreactivation of killing in E. coli K-12 phr- cells is not caused by pyrimidine dimer reversal.

  Photochemistry and Photobiology. 1988;48(2):233-234.
  3

• 284.

  1988

  I. Husain; J. Griffith; A. Sancar

  Thymine dimers bend DNA.

  Proceedings of the National Academy of Sciences of the United States of America. 1988;85(8):2558-2562.
  65

• 285.

  1988

  J.L. Johnson; S. Hamm-Alvarez; G. Payne; G.B. Sancar; K.V. Rajagopalan; A. Sancar

  Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate

  Proceedings of the National Academy of Sciences of the United States of America. 1988;85(7):2046-2050.
  65

• 286.

  1988

  Christopher P. Selby; Aziz Sancar

  ABC excinuclease incises both 5′ and 3′ to the CC-1065-DNA adduct and its incision activity is stimulated by DNA helicase II and DNA polymerase I

  Biochemistry. 1988;27(19):7184-7188.
  11

• 287.

  1988

  S. Cheng; B. Van Houten; H.B. Gamper; A. Sancar; J.E. Hearst

  Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease

  Journal of Biological Chemistry. 1988;263(29):15110-15117.
  52

• 288.

  1988

  B. Van Houten; H. Gamper; J.E. Hearst; A. Sancar

  Analysis of sequential steps of nucleotide excision repair in Escherichia coli using synthetic substrates containing single psoralen adducts

  Journal of Biological Chemistry. 1988;263(32):16553-16560.
  25

• 289.

  1988

  A. Sancar; G.B. Sancar

  DNA repair enzymes

  Annual Review of Biochemistry. 1988;57:29-67.
  307

• 290.

  1988

  D.C. Thomas; A.G. Morton; V.A. Bohr; A. Sancar

  General method for quantifying base adducts in specific mammalian genes

  Proceedings of the National Academy of Sciences of the United States of America. 1988;85(11):3723-3727.
  20

• 291.

  1987

  I. Husain; G.B. Sancar; S.R. Holbrook; A. Sancar

  Mechanism of damage recognition by Escherichia coli DNA photolyase.

  Journal of Biological Chemistry. 1987;262(27):13188-13197.
  31

• 292.

  1987

  B. Van Houten; H. Gamper; A. Sancar; J.E. Hearst

  DNase I footprint of ABC excinuclease.

  Journal of Biological Chemistry. 1987;262(27):13180-13187.
  37

• 293.

  1987

  Intisar Husian; Aziz Sancar

  Binding of E. coli DNA photolyase to a defined substrate containing a single T< >T dimer

  Nucleic Acids Research. 1987;15(3):1109-1120.
  35

• 294.

  1987

  Gary M. Myles; Bennett van Houten; Aziz Sancar

  Utilization of DNA photolyase, pyrimidine dimer endonucleases, and alkali hydrolysis in the analysis of aberrant ABC excinuclease incisions adjacent to UV-induced DNA photoproducts

  Nucleic Acids Research. 1987;15(3):1227-1243.
  11

• 295.

  1987

  M.S. Jorns; E.T. Baldwin; G.B. Sancar; A. Sancar

  Action mechanism of Escherichia coli DNA photolyase. II. Role of the chromophores in catalysis

  Journal of Biological Chemistry. 1987;262(1):486-491.
  30

• 296.

  1987

  B. Van Houten; A. Sancar

  Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease

  Journal of Bacteriology. 1987;169(2):540-545.
  21

• 297.

  1987

  I. Husain; A. Sancar

  Photoreactivation in phr mutants of escherichia coli K-12

  Journal of Bacteriology. 1987;169(6):2367-2372.
  2

• 298.

  1987

  D.K. Orren; A. Sancar

  New discoveries in the enzymology of DNA repair

  Cancer Reviews. 1987;7:5-27.
  0

• 299.

  1987

  Gillian Payne; Paul F. Heelis; Brian R. Rohrs; Aziz Sancar

  The active form of Escherichia coli DNA photolyase contains a fully reduced flavin and not a flavin radical, both in vivo and in vitro

  Biochemistry. 1987;26(22):7121-7127.
  40

• 300.

  1987

  Gwendolyn B. Sancar; Aziz Sancar

  Structure and function of DNA photolyases

  Trends in Biochemical Sciences. 1987;12(C):259-261.
  16

• 301.

  1986

  Stanley K. Mauldin; Fred A. Richard; Marcus Plescia; Steven D. Wyrick; Aziz Sancar; Stephen G. Chaney

  High-performance liquid chromatographic separation of platinum complexes containing the cis-1,2-diaminocyclohexane carrier ligand

  Analytical Biochemistry. 1986;157(1):129-143.
  8

• 302.

  1986

  E. Arikan; M.S. Kulkarni; D.C. Thomas; A. Sancar

  Sequences of the E. coli uvrB gene and protein

  Nucleic Acids Research. 1986;14(6):2637-2650.
  24

• 303.

  1986

  B. Van Houten; H. Gamper; J.E. Hearst; A. Sancar

  Construction of DNA substrates modified with psoralen at a unique site and study of the action mechanism of ABC excinuclease on these uniformly modified substrates

  Journal of Biological Chemistry. 1986;261(30):14135-14141.
  29

• 304.

  1986

  I. Husain; B. Van Houten; D.C. Thomas; A. Sancar

  Sequences of Escherichia coli uvrA gene and protein reveal two potential ATP binding sites

  Journal of Biological Chemistry. 1986;261(11):4895-4901.
  27

• 305.

  1986

  B. van Houten; H. Gamper; S.R. Holbrook; J.E. Hearst; A. Sancar

  Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position

  Proceedings of the National Academy of Sciences of the United States of America. 1986;83(21):8077-8081.
  91

• 306.

  1986

  S.K. Mauldin; I. Husain; A. Sancar; S.G. Chaney

  Effects of the bidentate malonate ligand on the utilization and cytotoxicity of platinum compounds in the L1210 cell line

  Cancer Research. 1986;46(6):2876-2882.
  10

• 307.

  1985

  D.J. Beck; S. Popoff; A. Sancar; W.D. Rupp

  Reactions of the UVRABC excision nuclease with DNA damaged by diamminedichloroplatinum(II)

  Nucleic Acids Research. 1985;13(20):7395-7412.
  19

• 308.

  1985

  I. Husain; B. van Houten; D.C. Thomas; M. Abdel-Monem; A. Sancar

  Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease

  Proceedings of the National Academy of Sciences of the United States of America. 1985;82(20):6774-6778.
  49

• 309.

  1985

  A. Sancar; K.A. Franklin; G. Sancar

  Repair of psoralen and acetylaminofluorene DNA adducts by ABC excinuclease

  Journal of Molecular Biology. 1985;184(4):725-734.
  11

• 310.

  1985

  I. Husain; S.G. Chaney; A. Sancar

  Repair of cis-platinum-DNA adducts by ABC excinuclease in vivo and in vitro

  Journal of Bacteriology. 1985;163(3):817-823.
  17

• 311.

  1985

  Marilyn Schuman Jorns; Gwendolyn B. Sancar; Aziz Sancar

  Identification of oligothymidylates as new simple substrates for Escherichia coli DNA photolyase and their use in a rapid spectrophotometric enzyme assay

  Biochemistry. 1985;24(8):1856-1861.
  28

• 312.

  1985

  G.B. Sancar; F.W. Smith; A. Sancar

  Binding of Escherichia coli DNA photolyase to UV-irradiated DNA

  Biochemistry. 1985;24(8):1849-1855.
  27

• 313.

  1985

  D.C. Thomas; M. Levy; A. Sancar

  Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli

  Journal of Biological Chemistry. 1985;260(17):9875-9883.
  31

• 314.

  1984

  Bruce E. Markham; Joan E. Harper; David W. Mount; Gwendolyn B. Sancar; Aziz Sancar; W.Dean Rupp; Cynthia J. Kenyon; Graham C. Walker

  Analysis of mRNA synthesis following induction of the Escherichia coli SOS system

  Journal of Molecular Biology. 1984;178(2):237-248.
  5

• 315.

  1984

  Gwendolyn B. Sancar; Aziz Sancar; W.Dean Rupp

  Sequences of the E. coli uvrC gene and protein

  Nucleic Acids Research. 1984;12(11):4593-4608.
  11

• 316.

  1984

  Aziz Sancar; Gwendolyn B. Sancar

  Escherichia coli DNA photolyase is a flavoprotein

  Journal of Molecular Biology. 1984;172(2):223-227.
  20

• 317.

  1984

  Marilyn Schuman Jorns; Gwendolyn B. Sancar; Aziz Sancar

  Identification of a neutral flavin radical and characterization of a second chromophore in Escherichia coli DNA photolyase

  Biochemistry. 1984;23(12):2673-2679.
  57

• 318.

  1984

  A. Sancar; F.W. Smith; G.B. Sancar

  Purification of Escherichia coli DNA photolyase

  Journal of Biological Chemistry. 1984;259(9):6028-6032.
  39

• 319.

  1984

  G.B. Sancar; F.W. Smith; M.C. Lorence; C.S. Rupert; A. Sancar

  Sequences of the Escherichia coli photolyase gene and protein

  Journal of Biological Chemistry. 1984;259(9):6033-6038.
  16

• 320.

  1983

  Gwendolyn B. Sancar; Frances W. Smith; Aziz Sancar

  Identification and amplification of the E. coli phr gene product

  Nucleic Acids Research. 1983;11(19):6667-6678.
  12

• 321.

  1983

  A. Sancar; W.D. Rupp

  A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

  Cell. 1983;33(1):249-260.
  94

• 322.

  1982

  W. Dean Rupp; Aziz Sancar; Gwendolyn B. Sancar

  Properties and regulation of the UVRABC endonuclease

  Biochimie. 1982;64(8-9):595-598.
  7

• 323.

  1982

  Bernt Eric Uhlin; Michael R. Volkert; Alvin J. Clark; Aziz Sancar; W.Dean Rupp

  Nucleotide sequence of a recA operator mutation - lexA/operator-repressor binding/inducible repair

  MGG Molecular & General Genetics. 1982;185(2):251-254.
  4

• 324.

  1982

  Gwendolyn B. Sancar; Aziz Sancar; John W. Little; W.Dean Rupp

  The uvrB gene of Escherichia coli has both lexA-repressed and lexA-independent promoters

  Cell. 1982;28(3):523-530.
  9

• 325.

  1982

  A. Sancar; G.B. Sancar; W.D. Rupp; J.W. Little; D.W. Mount

  LexA protein inhibits transcription of the E. coli uvrA gene in vitro

  Nature. 1982;298(5869):96-98.
  3

• 326.

  1981

  Aziz Sancar; Robin P. Wharton; Samuel Seltzer; Barry M. Kacinski; Neil D. Clarke; W.Dean Rupp

  Identification of the uvrA gene product

  Journal of Molecular Biology. 1981;148(1):45-62.
  12

• 327.

  1981

  A. Sancar; N.D. Clarke; J. Griswold; W.J. Kennedy; W.D. Rupp

  Identification of the uvrB gene product

  Journal of Molecular Biology. 1981;148(1):63-76.
  2

• 328.

  1981

  A. Sancar; B.M. Kacinski; D.L. Mott; W.D. Rupp

  Identification of the uvrC gene product

  Proceedings of the National Academy of Sciences of the United States of America. 1981;78(9 II):5450-5454.
  1

• 329.

  1981

  B.M. Kacinski; A. Sancar; W.D. Rupp

  A general approach for purifying proteins encoded by cloned genes without using a functional assay: Isolation of the uvrA gene product from radiolabeled maxicells

  Nucleic Acids Research. 1981;9(18):4495-4508.
  3

• 330.

  1981

  A. Sancar; K.R. Williams; J.W. Chase; W.D. Rupp

  Sequences of the ssb gene and protein

  Proceedings of the National Academy of Sciences of the United States of America. 1981;78(7 I):4274-4278.
  51

• 331.

  1980

  John W. Chase; Robert F. Whittier; Jeffrey Auerbach; Aziz Sancar; W. Dean Rupp

  Amplification of single-strand DNA binding protein in escherichis coli

  Nucleic Acids Research. 1980;8(14):3215-3228.
  14

• 332.

  1980

  A. Sancar; C. Stachelek; W.W.D. Koningsberg Rupp

  Sequences of the recA gene and protein

  Proceedings of the National Academy of Sciences of the United States of America. 1980;77(5 I):2611-2615.
  36

• 333.

  1979

  A. Sancar; W.D. Rupp

  Cloning of uvrA, lexC and ssb genes of Escherichia coli

  Biochemical and Biophysical Research Communications. 1979;90(1):123-129.
  5

• 334.

  1979

  A. Sancar; W.D. Rupp

  Physical map of the recA gene

  Proceedings of the National Academy of Sciences of the United States of America. 1979;76(7):3144-3148.
  3

• 335.

  1979

  A. Sancar; A.M. Hack; W.D. Rupp

  Simple method for identification of plasmid-coded proteins

  Journal of Bacteriology. 1979;137(1):692-693.
  82

• 336.

  1979

  A. Sancar; C.S. Rupet

  Penicillin selection of Escherichia coli deoxyribonucleic acid repair mutants

  Journal of Bacteriology. 1979;138(3):779-782.
  0

• 337.

  1978

  Aziz Sancar; Claud S. Rupert

  Cloning of the phr gene and amplification of photolyase in Escherichia coli

  Gene. 1978;4(4):295-308.
  13

• 338.

  1978

  A. Sancar; C.S. Rupert

  Correction of the map location for the phr gene in Escherichia coli K12

  Mutation Research. 1978;51(1):139-143.
  2

• 339.

  1978

  A. Sancar; C.S. Rupert

  Determination of plasmid molecular weights from ultraviolet sensitivities

  Nature. 1978;272(5652):471-472.
  9