Christopher P Mack

UNCCH, School of Medicine, Pathology and Laboratory Medicine

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Christopher P Mack

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Pathology and Laboratory Medicine
  
  

This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2012

  Zhaokang Cheng; Laura A. Dimichele; Zeenat S. Hakim; Mauricio Rojas; Christopher P. MacK; Joan M. Taylor

  Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia/reperfusion injury

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2012;32(4):924-933.
  2

• 2.

  2012

  Matt D. Medlin; Joan M. Taylor; Christopher P. MacK

  Quantifying sphingosine-1-phosphate-dependent activation of the rhoGTPases

  Methods in Molecular Biology. 2012;874:89-97.
  0

• 3.

  2012

  Thomas J. O'Neill; Christopher P. Mack; Joan M. Taylor

  Germline deletion of FAK-related non-kinase delays post-natal cardiomyocyte mitotic arrest

  Journal of Molecular and Cellular Cardiology. 2012;53(2):156-164.
  0

• 4.

  2011

  Dean P. Staus; Alicia L. Blaker; Matt D. Medlin; Joan M. Taylor; Christopher P. Mack

  Formin homology domain-containing protein 1 regulates smooth muscle cell phenotype

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2011;31(2):360-367.
  5

• 5.

  2011

  Christopher P. MacK

  Signaling mechanisms that regulate smooth muscle cell differentiation

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2011;31(7):1495-1505.
  12

• 6.

  2011

  Jason T. Doherty; Kaitlin C. Lenhart; Morgan V. Cameron; Christopher P. Mack; Frank L. Conlon; Joan M. Taylor

  Skeletal muscle differentiation and fusion are regulated by the BAR-containing Rho-GTPase-activating Protein (Rho-GAP), GRAF

  Journal of Biological Chemistry. 2011;286(29):25903-25921.
  4

• 7.

  2011

  Dean P. Staus; Joan M. Taylor; Christopher P. Mack

  Enhancement of mDia2 activity by Rho-kinase-dependent phosphorylation of the diaphanous autoregulatory domain

  Biochemical Journal. 2011;439(1):57-65.
  3

• 8.

  2011

  Zhaokang Cheng; Liisa J. Sundberg-Smith; Lee E. Mangiante; Rebecca L. Sayers; Zeenat S. Hakim; Srilaxmi Musunuri; Colin T. Maguire; Mark W. Majesky; Zhigang Zhou; Christopher P. MacK; et al.

  Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2011;31(10):2193-2202.
  2

• 9.

  2010

  Matt D. Medlin; Dean P. Staus; Adi D. Dubash; Joan M. Taylor; Christopher P. MacK

  Sphingosine 1-phosphate receptor 2 signals through leukemia-associated RhoGEF (LARG), to promote smooth muscle cell differentiation

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2010;30(9):1779-1786.
  14

• 10.

  2010

  Jason T. Doherty; Frank L. Conlon; Christopher P. Mack; Joan M. Taylor

  Focal adhesion kinase is essential for cardiac looping and multichamber heart formation

  Genesis. 2010;48(8):492-504.
  4

• 11.

  2009

  Zeenat S. Hakim; Laura A. DiMichele; Mauricio Rojas; Dane Meredith; Christopher P. Mack; Joan M. Taylor

  FAK regulates cardiomyocyte survival following ischemia/reperfusion

  Journal of Molecular and Cellular Cardiology. 2009;46(2):241-248.
  13

• 12.

  2009

  Laura A. Dimichele; Zeenat S. Hakim; Rebecca L. Sayers; Mauricio Rojas; Robert J. Schwartz; Christopher P. MacK; Joan M. Taylor

  Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth

  Circulation Research. 2009;104(10):1201-1208.
  11

• 13.

  2009

  Alicia L. Blaker; Joan M. Taylor; Christopher P. MacK

  PKA-dependent phosphorylation of serum response factor inhibits smooth muscle-specific gene expression

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2009;29(12):2153-2160.
  4

• 14.

  2008

  Liisa J. Sundberg-Smith; Laura A. Dimichele; Rebecca L. Sayers; Christopher P. MacK; Joan M. Taylor

  The LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcription

  Circulation Research. 2008;102(12):1502-1511.
  7

• 15.

  2008

  Christopher P. MacK

  Editorial: An epigenetic clue to diabetic vascular disease

  Circulation Research. 2008;103(6):568-570.
  7

• 16.

  2008

  Jeremiah S. Hinson; Matt D. Medlin; Joan M. Taylor; Christopher P. Mack

  Regulation of myocardin factor protein stability by the LIM-only protein FHL2

  American Journal of Physiology - Heart and Circulatory Physiology. 2008;295(3):H1067-H1075.
  9

• 17.

  2008

  Rebecca L. Sayers; Liisa J. Sundberg-Smith; Mauricio Rojas; Haruko Hayasaka; J. Thomas Parsons; Christopher P. Mack; Joan M. Taylor

  FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2008;28(12):2115-2122.
  13

• 18.

  2007

  Jeremiah S. Hinson; Matthew D. Medlin; Kashelle Lockman; Joan M. Taylor; Christopher P. Mack

  Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors

  American Journal of Physiology - Heart and Circulatory Physiology. 2007;292(2):H1170-H1180.
  39

• 19.

  2007

  Dean P. Staus; Alicia L. Blaker; Joan M. Taylor; Christopher P. Mack

  Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors

  Arteriosclerosis, Thrombosis, and Vascular Biology. 2007;27(3):478-486.
  18

• 20.

  2007

  Zeenat S. Hakim; Laura A. DiMichele; Jason T. Doherty; Jonathon W. Homeister; Hilary E. Beggs; Louis F. Reichardt; Robert J. Schwartz; Joseph Brackhan; Oliver Smithies; Christopher P. Mack; et al.

  Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment

  Molecular and Cellular Biology. 2007;27(15):5352-5364.
  34

• 21.

  2007

  Kashelle Lockman; Joan M. Taylor; Christopher P. Mack

  The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression

  Circulation Research. 2007;101(12):e115-e123.
  26

• 22.

  2006

  Laura A. DiMichele; Jason T. Doherty; Mauricio Rojas; Hilary E. Beggs; Louis F. Reichardt; Christopher P. Mack; Joan M. Taylor

  Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy

  Circulation Research. 2006;99(6):636-645.
  42

• 23.

  2005

  Liisa J. Sundberg-Smith; Jason T. Doherty; Christopher P. Mack; Joan M. Taylor

  Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr²¹² phosphorylation

  Journal of Biological Chemistry. 2005;280(3):2055-2064.
  33

• 24.

  2005

  Christopher Mack; J.S. Hinson

  Regulation of smooth muscle differentiation by the myocardin family of serum response factor co-factors

  Journal of Thrombosis and Haemostasis. 2005;3(9):1976-1984.
  13

• 25.

  2004

  Kashelle Lockman; Jeremiah S. Hinson; Matt D. Medlin; Dionne Morris; Joan M. Taylor; Christopher P. Mack

  Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors

  Journal of Biological Chemistry. 2004;279(41):42422-42430.
  83

• 26.

  2003

  Liisa J. Sundberg; Lisa M. Galante; Heather M. Bill; Christopher P. Mack; Joan M. Taylor

  An endogenous inhibitor of focal adhesion kinase blocks Rac1/JNK but not Ras/ERK-dependent signaling in vascular smooth muscle cells

  Journal of Biological Chemistry. 2003;278(32):29783-29791.
  47

• 27.

  2001

  J.M. Taylor; C.P. Mack; K. Nolan; C.P. Regan; G.K. Owens; J.T. Parsons

  Selective expression of an endogenous inhibitor of FAK regulates proliferation and migration of vascular smooth muscle cells

  Molecular and Cellular Biology. 2001;21(5):1565-1572.
  112

• 28.

  2001

  B. Settles; A. Stevenson; K. Wilson; C. Mack; T. Ezell; M.F. Davis; L.D. Taylor

  Down-regulation of cell adhesion molecules LFA-1 and ICAM-1 after in vitro treatment with the anti-TNF-alpha agent thalidomide.

  Cellular and Molecular Biology. 2001;47(7):1105-1114.
  40

• 29.

  2001

  Christopher P. Mack; Avril V. Somlyo; Martina Hautmann; Andrew P. Somlyo; Gary K. Owens

  Smooth muscle differentiation marker gene expression is regulated by Rhoa-mediated actin polymerization

  Journal of Biological Chemistry. 2001;276(1):341-347.
  233

• 30.

  2000

  Christopher P. Mack; Maria M. Thompson; Susan Lawrenz-Smith; Gary K. Owens

  Smooth muscle a-actin CArG elements coordinate formation of a smooth muscle cell-selective, serum response factor-containing activation complex

  Circulation Research. 2000;86(2):221-232.
  79

• 31.

  1999

  Christopher P. Mack; Gary K. Owens

  Regulation of smooth muscle α-actin expression in vivo is dependent on CArG elements within the 5' and first intron promoter regions

  Circulation Research. 1999;84(7):852-861.
  156

• 32.

  1998

  Joan M. Taylor; Jeffrey D. Hildebrand; Christopher P. Mack; Michael E. Cox; J. Thomas Parsons

  Characterization of Graf, the GTPase-activating protein for Rho associated with focal adhesion kinase. Phosphorylation and possible regulation by mitogen-activated protein kinase

  Journal of Biological Chemistry. 1998;273(14):8063-8070.
  42

• 33.

  1998

  Martina B. Hautmann; Cort S. Madsen; Christopher P. Mack; Gary K. Owens

  Substitution of the degenerate smooth muscle (SM) α-actin CC(A/T- rich)₆GG elements with c-fos serum response elements results in increased basal expression but relaxed SM cell specificity and reduced angiotensin II inducibility

  Journal of Biological Chemistry. 1998;273(14):8398-8406.
  43

• 34.

  1995

  Christopher P. Mack; Donald E. Hultquist; Marshal Shlafer

  Myocardial flavin reductase and riboflavin: A potential role in decreasing reoxygenation injury

  Biochemical and Biophysical Research Communications. 1995;212(1):35-40.
  17

• 35.

  1993

  F. Xu; C.P. Mack; K.S. Quandt; M. Shlafer; V. Massey; D.E. Hultquist

  Pyrroloquinoline quinone acts with flavin reductase to reduce ferryl myoglobin in vitro and protects isolated heart from re-oxygenation injury

  Biochemical and Biophysical Research Communications. 1993;193(1):434-439.
  24

• 36.

  1993

  C.P. Mack; K.M. Brosamer; M. Shlafer

  Ultrastructural demonstration of peroxidative activity and peroxidation in ischaemic and ischaemic-reperfused rabbit hearts

  Cardiovascular Research. 1993;27(3):371-376.
  2

• 37.

  1993

  D.E. Hultquist; K.S. Quandt; M. Shlafer; C.P. Mack; G.O. Till; A. Seekamp; A.L. Betz; S.R. Ennis; F. Xu

  Evidence that NADPH-dependent methemoglobin reductase and administered riboflavin protect tissues from oxidative injury

  American Journal of Hematology. 1993;42(1):13-18.
  36