Dale A Ramsden

UNCCH, School of Medicine, Biochemistry and Biophysics

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Dale A Ramsden

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Biochemistry and Biophysics
  
  

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  Susovan Mohapatra; Steven M. Yannone; Suk-Hee Lee; Robert A. Hromas; Konstantin Akopiants; Vijay Menon; Dale A. Ramsden; Lawrence F. Povirk

  Trimming of damaged 3′ overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleases

  DNA Repair. 2013.
  0

• 2.

  2012

  Natasha Tiffany Strande; Crystal Ann Waters; Dale A. Ramsden

  Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?

  Genome Integrity. 2012;3.
  1

• 3.

  2012

  Dale A. Ramsden; Kenjiro Asagoshi

  DNA polymerases in nonhomologous end joining: Are there any benefits to standing out from the crowd?

  Environmental and Molecular Mutagenesis. 2012;53(9):741-751.
  0

• 4.

  2012

  Matthew J Schellenberg; C Denise Appel; Sanjay Adhikari; Patrick D Robertson; Dale A Ramsden; R. Scott Williams

  Mechanism of repair of 5′-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2

  Nature Structural and Molecular Biology. 2012;19(12):1363-1371.
  4

• 5.

  2012

  Natasha Strande; Steven A. Roberts; Sehyun Oh; Eric A. Hendrickson; Dale A. Ramsden

  Specificity of the dRP/AP lyase of ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends

  Journal of Biological Chemistry. 2012;287(17):13686-13693.
  6

• 6.

  2011

  Dale A. Ramsden

  Polymerases in nonhomologous end joining: Building a bridge over broken chromosomes

  Antioxidants and Redox Signaling. 2011;14(12):2509-2519.
  9

• 7.

  2010

  Rajam S. Mani; Yaping Yu; Shujuan Fang; Meiling Lu; Mesfin Fanta; Angela E. Zolner; Nasser Tahbaz; Dale A. Ramsden; David W. Litchfield; Susan P. Lees-Miller; et al.

  Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: Implications for nonhomologous end joining

  Journal of Biological Chemistry. 2010;285(48):37619-37629.
  17

• 8.

  2010

  Dale A. Ramsden; Brett D. Weed; Yeturu V.R. Reddy

  V(D)J recombination: Born to be wild

  Seminars in Cancer Biology. 2010;20(4):254-260.
  3

• 9.

  2010

  Rika Kusumoto-Matsuo; Patricia L. Opresko; Dale Ramsden; Hidetoshi Tahara; Vilhelm A. Bohr

  Cooperation of DNA-pkcs and WRN helicase in the maintenance of telomeric D-loops

  Aging. 2010;2(5):274-284.
  12

• 10.

  2010

  Steven A. Roberts; Natasha Strande; Martin D. Burkhalter; Christina Strom; Jody M. Havener; Paul Hasty; Dale A. Ramsden

  Ku is a 5′-dRP/AP lyase that excises nucleotide damage near broken ends

  Nature. 2010;464(7292):1214-1217.
  36

• 11.

  2009

  Martin D. Burkhalter; Steven A. Roberts; Jody M. Havener; Dale A. Ramsden

  Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks

  DNA Repair. 2009;8(11):1258-1263.
  9

• 12.

  2009

  Miguel Garcia-Diaz; Katarzyna Bebenek; Andres A. Larrea; Jody M. Havener; Lalith Perera; Joseph M. Krahn; Lars C. Pedersen; Dale A. Ramsden; Thomas A. Kunkel

  Template strand scrunching during DNA gap repair synthesis by human polymerase λ

  Nature Structural and Molecular Biology. 2009;16(9):967-972.
  19

• 13.

  2009

  Tong Zhou; Konstantin Akopiants; Susovan Mohapatra; Peck-Sun Lin; Kristoffer Valerie; Dale A. Ramsden; Susan P. Lees-Miller; Lawrence F. Povirk

  Tyrosyl-DNA phosphodiesterase and the repair of 3′-phosphoglycolate-terminated DNA double-strand breaks

  DNA Repair. 2009;8(8):901-911.
  17

• 14.

  2008

  Geoffrey A. Mueller; Andrea F. Moon; Eugene F. DeRose; Jody M. Havener; Dale A. Ramsden; Lars C. Pedersen; Robert E. London

  A comparison of BRCT domains involved in nonhomologous end-joining: Introducing the solution structure of the BRCT domain of polymerase lambda

  DNA Repair. 2008;7(8):1340-1351.
  11

• 15.

  2008

  Rika Kusumoto; Lala Dawut; Caterina Marchetti; Wan Lee Jae; Alessandro Vindigni; Dale Ramsden; Vilhelm A. Bohr

  Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing

  Biochemistry. 2008;47(28):7548-7556.
  20

• 16.

  2008

  Bryan J. Davis; Jody M. Havener; Dale A. Ramsden

  End-bridging is required for pol μ to efficiently promote repair of noncomplementary ends by nonhomologous end joining

  Nucleic Acids Research. 2008;36(9):3085-3094.
  30

• 17.

  2008

  Zuzanna Bukowy; Jeanine A. Harrigan; Dale A. Ramsden; Barbara Tudek; Vilhelm A. Bohr; Tinna Stevnsner

  WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand

  Nucleic Acids Research. 2008;36(15):4975-4987.
  11

• 18.

  2007

  Eugene F. DeRose; Michael W. Clarkson; Steven A. Gilmore; Cristina J. Galban; Ashutosh Tripathy; Jody M. Havener; Geoffrey A. Mueller; Dale A. Ramsden; Robert E. London; et al.

  Solution structure of polymerase μ's BRCT domain reveals an element essential for its role in nonhomologous end joining

  Biochemistry. 2007;46(43):12100-12110.
  12

• 19.

  2007

  Andrea F. Moon; Miguel Garcia-Diaz; Katarzyna Bebenek; Bryan J. Davis; Xuejun Zhong; Dale A. Ramsden; Thomas A. Kunkel; Lars C. Pedersen

  Erratum: Structural insight into the substrate specificity of DNA Polymerase μ (Nature Structural and Molecular Biology (2007) 14, (45-53))

  Nature Structural and Molecular Biology. 2007;14(7):680.
  0

• 20.

  2007

  Lawrence F. Povirk; Rui-Zhe Zhou; Dale A. Ramsden; Susan P. Lees-Miller; Kristoffer Valerie

  Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts

  Nucleic Acids Research. 2007;35(12):3869-3878.
  17

• 21.

  2007

  Steven A. Roberts; Dale A. Ramsden

  Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends

  Journal of Biological Chemistry. 2007;282(14):10605-10613.
  14

• 22.

  2007

  Andrea F. Moon; Miguel Garcia-Diaz; Katarzyna Bebenek; Bryan J. Davis; Xuejun Zhong; Dale A. Ramsden; Thomas A. Kunkel; Lars C. Pedersen

  Structural insight into the substrate specificity of DNA Polymerase μ

  Nature Structural and Molecular Biology. 2007;14(1):45-53.
  38

• 23.

  2006

  Raquel Juárez; José F. Ruiz; Stephanie A. Nick McElhinny; Dale Ramsden; Luis Blanco

  A specific loop in human DNA polymerase mu allows switching between creative and DNA-instructed synthesis

  Nucleic Acids Research. 2006;34(16):4572-4582.
  32

• 24.

  2006

  Yeturu V.R. Reddy; Eric J. Perkins; Dale A. Ramsden

  Genomic instability due to V(D)J recombination-associated transposition

  Genes and Development. 2006;20(12):1575-1582.
  36

• 25.

  2005

  Stephanie A. Nick McElhinny; Jody M. Havener; Miguel Garcia-Diaz; Raquel Juárez; Katarzyna Bebenek; Barbara L. Kee; Luis Blanco; Thomas A. Kunkel; Dale A. Ramsden

  A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining

  Molecular Cell. 2005;19(3):357-366.
  146

• 26.

  2004

  Yeturu V. R. Reddy; Qi Ding; Susan P. Lees-Miller; Katheryn Meek; Dale A. Ramsden

  Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends

  Journal of Biological Chemistry. 2004;279(38):39408-39413.
  63

• 27.

  2004

  Katheryn Meek; Shikha Gupta; Dale A. Ramsden; Susan P. Lees-Miller

  The DNA-dependent protein kinase: The director at the end

  Immunological Reviews. 2004;200:132-141.
  124

• 28.

  2004

  Stephanie A. Nick McElhinny; Dale A. Ramsden

  Sibling rivalry: Competition between Pol X family members in V(D)J recombination and general double strand break repair

  Immunological Reviews. 2004;200:156-164.
  34

• 29.

  2004

  Lindsay G. Cowell; Marco Davila; Dale Ramsden; Garnett Kelsoe

  Computational tools for understanding sequence variability in recombination signals

  Immunological Reviews. 2004;200:57-69.
  11

• 30.

  2004

  Eric J. Perkins; Barbara L. Kee; Dale A. Ramsden

  Histone 3 lysine 4 methylation during the pre-B to immature B-cell transition

  Nucleic Acids Research. 2004;32(6):1942-1947.
  20

• 31.

  2003

  Qi Ding; Yeturu V. R. Reddy; Wei Wang; Timothy Woods; Pauline Douglas; Dale A. Ramsden; Susan P. Lees-Miller; Katheryn Meek

  Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

  Molecular and Cellular Biology. 2003;23(16):5836-5848.
  148

• 32.

  2003

  Stephanie A. Nick McElhinny; Dale A. Ramsden

  Polymerase Mu is a DNA-directed DNA/RNA polymerase

  Molecular and Cellular Biology. 2003;23(7):2309-2315.
  73

• 33.

  2003

  Jody M. Havener; Stephanie A. Nick McElhinny; Ekaterina Bassett; Michele Gauger; Dale A. Ramsden; Stephen G. Chaney

  Translesion synthesis past platinum DNA adducts by human DNA polymerase μ

  Biochemistry. 2003;42(6):1777-1788.
  33

• 34.

  2003

  Dale Ramsden; Yi Zhang

  Everything is E(Z): Linking histone methylation to B cell development

  Nature Immunology. 2003;4(2):101-103.
  3

• 35.

  2002

  Parimal Karmakar; Carey M. Snowden; Dale A. Ramsden; Vilhelm A. Bohr

  Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus

  Nucleic Acids Research. 2002;30(16):3583-3591.
  58

• 36.

  2002

  Parimal Karmakar; Jason Piotrowski; Robert M. Brosh Jr.; Joshua A. Sommers; Susan P. Lees Miller; Wen-Hsing Cheng; Carey M. Snowden; Dale A. Ramsden; Vilhelm A. Bohr

  Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

  Journal of Biological Chemistry. 2002;277(21):18291-18302.
  101

• 37.

  2002

  Eric J. Perkins; Ayyappan Nair; Dale O. Cowley; Terry Van Dyke; Yung Chang; Dale A. Ramsden

  Sensing of intermediates in V(D)J recombination by ATM

  Genes and Development. 2002;16(2):159-164.
  82

• 38.

  2002

  Kiran N. Mahajan; Stephanie A. Nick McElhinny; Beverly S. Mitchell; Dale A. Ramsden

  Association of DNA polymerase μ (pol μ) with Ku and ligase IV: Role for pol μ in end-joining double-strand break repair

  Molecular and Cellular Biology. 2002;22(14):5194-5202.
  174

• 39.

  2000

  Stephanie A. Nick McElhinny; Carey M. Snowden; Joseph McCarville; Dale A. Ramsden

  Ku recruits the XRCC4-ligase IV complex to DNA ends

  Molecular and Cellular Biology. 2000;20(9):2996-3003.
  213

• 40.

  2000

  Marcus P. Cooper; Amrita Machwe; David K. Orren; Robert M. Brosh; Dale Ramsden; Vilhelm A. Bohr

  Ku complex interacts with and stimulates the Werner protein

  Genes and Development. 2000;14(8):907-912.
  213

• 41.

  1999

  M. Gellert; J.E. Hesse; K. Hiom; M. Melek; M. Modesti; T.T. Paull; D.A. Ramsden; D.C. Van Gent

  V(D)J recombination: Links to transposition and double-strand break repair

  Cold Spring Harbor Symposia on Quantitative Biology. 1999;64:161-167.
  14

• 42.

  1998

  Dale A. Ramsden; Martin Geliert

  Ku protein stimulates DNA end joining by mammalian DNA ligases: A direct role for Ku in repair of DNA double-strand breaks

  EMBO Journal. 1998;17(2):609-614.
  201

• 43.

  1997

  Dale A Ramsden; Dik C Van Gent; Martin Gellert

  Specificity in V(D)J recombination: New lessons from biochemistry and genetics

  Current Opinion in Immunology. 1997;9(1):114-120.
  28

• 44.

  1997

  Dale A. Ramsden; Tanya T. Paull; Martin Gellert

  Cell-free V(D)J recombination

  Nature. 1997;388(6641):488-491.
  107

• 45.

  1996

  Dik C. Van Gent; Dale A. Ramsden; Martin Gellert

  The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

  Cell. 1996;85(1):107-113.
  206

• 46.

  1996

  D.C. Van Gent; J.F. McBlane; D.A. Ramsden; M.J. Sadofsky; J.E. Hesse; M. Gellert

  Initiation of V(D)J recombination in a cell-free system by RAG1 and RAG2 proteins

  Current Topics in Microbiology and Immunology. 1996;217:1-10.
  13

• 47.

  1996

  Dale A. Ramsden; J. Fraser McBlane; Dik C. Van Gent; Martin Geliert

  Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage

  EMBO Journal. 1996;15(12):3197-3206.
  128

• 48.

  1996

  Liam Fanning; Alison Connor; Kristen Baetz; Dale Ramsden; Gillian E. Wu

  Mouse RSS spacer sequences affect the rate of V(D)J recombination

  Immunogenetics. 1996;44(2):146-150.
  19

• 49.

  1996

  Dik C. Van Gent; J. Fraser McBlane; Dale A. Ramsden; Moshe J. Sadofsky; Joanne E. Hesse; Martin Gellert

  Initiation of V(D)J recombination in a cell-free system by RAG1 and RAG2 proteins

  Current Topics in Microbiology and Immunology. 1996;217:X-10.
  4

• 50.

  1995

  J.Fraser McBlane; Dik C. van Gent; Dale A. Ramsden; Charles Romeo; Christina A. Cuomo; Martin Gellert; Marjorie A. Oettinger

  Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

  Cell. 1995;83(3):387-395.
  476

• 51.

  1995

  D.A. Ramsden; G.E. Wu

  Three new immunoglobulin kappa variable (Igk-V) gene segments in the mouse

  Immunogenetics. 1995;41(5):334.
  0

• 52.

  1995

  Alison M. Connor; Liam J. Fanning; Jakub W. Celler; Lisa K. Hicks; Dale A. Ramsden; E. Wu Gillian

  Mouse V_H7183 recombination signal sequences mediate recombination more frequently than those of VHJ558 1

  Journal of Immunology. 1995;155(11):5268-5272.
  37

• 53.

  1995

  D.C. Van Gent; J.F. McBlane; D.A. Ramsden; M.J. Sadofsky; J.E. Hesse; M. Gellert

  Initiation of V(D)J recombination in a cell-free system

  Cell. 1995;81(6):925-934.
  243

• 54.

  1995

  Tim Groves; Peter Katis; Zarina Madden; Kanchana Manickam; Dale Ramsden; Gillian Wu; Cynthia J. Guidos

  In vitro maturation of clonal CD4⁺CD8⁺ cell lines in response to TCR engagement

  Journal of Immunology. 1995;154(10):5011-5022.
  45

• 55.

  1995

  D.A. Ramsden; M. Gellert

  Formation and resolution of double-strand break intermediates in V(D)J rearrangement

  Genes and Development. 1995;9(19):2409-2420.
  121

• 56.

  1994

  Dale A. Ramsden; Christopher J. Paige; Gillian E. Wu

  κ Light chain rearrangement in mouse fetal liver

  Journal of Immunology. 1994;153(3):1150-1160.
  36

• 57.

  1994

  Dale A. Ramsden; Kristin Baetz; Gillian E. Wu

  Conservation of sequence in recombination signal sequence spacers

  Nucleic Acids Research. 1994;22(10):1785-1796.
  90

• 58.

  1994

  Ana Cumano; Barbara L. Kee; Dale A. Ramsden; Aaron Marshall; Christopher J. Paige; Gillian E. Wu

  Development of B lymphocytes from lymphoid committed and uncommitted progenitors

  Immunological Reviews. 1994;(137):5-33.
  24

• 59.

  1993

  A. Narendran; D. Ramsden; A. Cumano; T. Tanaka; G.E. Wu; C.J. Paige

  B cell developmental defects in X-linked immunodeficiency

  International Immunology. 1993;5(2):139-144.
  15

• 60.

  1992

  C.J. Paige; A. Cumano; D. Ramsden; G.E. Wu

  The K:λ ratio and B-cell development in the foetal liver

  Research in Immunology. 1992;143(8):822-824.
  0

• 61.

  1992

  D.A. Ramsden; G.E. Wu

  The virgin B cell K:λ ratio

  Research in Immunology. 1992;143(8):811-817.
  3

• 62.

  1991

  D.A. Ramsden; G.E. Wu

  Mouse κ light-chain recombination signal sequences mediate recombination more frequently than do those of λ light chain

  Proceedings of the National Academy of Sciences of the United States of America. 1991;88(23):10721-10725.
  70

• 63.

  1990

  G.E. Wu; M.J. Atkinson; D.A. Ramsden; C.J. Paige

  VH gene repertoire

  Seminars in Immunology. 1990;2(3):207-216.
  8

• 64.

  1989

  D.A. Ramsden; J. Chen; F.W. Miller; V. Misener; R.M. Bernstein; K.A. Siminovitch; F.W.L. Tsui

  Epitope mapping of the cloned human autoantigen, histidyl-tRNA synthetase. Analysis of the myositis-associated anti-Jo-1 autoimmune response

  Journal of Immunology. 1989;143(7):2267-2272.
  15