David M Margolis

UNCCH, School of Medicine, Medicine

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David M Margolis

• Organizations
  University of North Carolina at Chapel Hill
  
  School of Medicine
  
  Medicine
  
  

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This is a list of publications by this researcher, listed chronologically starting with the most recent first. New publications appear in this list weekly. The source of publications and 'cited by' data for this application is Scopus.

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• 1.

  2013

  David M. Margolis; Daria J. Hazuda

  Combined approaches for HIV cure

  Current Opinion in HIV and AIDS. 2013.
  0

• 2.

  2013

  Kirston Barton; David Margolis

  Selective targeting of the repressive transcription factors YY1 and cMyc to disrupt quiescent human immunodeficiency viruses

  AIDS Research and Human Retroviruses. 2013;29(2):289-298.
  0

• 3.

  2013

  Michael J. Vinikoor; Anna Cope; Cynthia L. Gay; Guido Ferrari; Kara S. McGee; Joann D. Kuruc; Jeffrey L. Lennox; David M. Margolis; Charles B. Hicks; Joseph J. Eron

  Antiretroviral therapy initiated during acute HIV infection fails to prevent persistent T cell activation

  Journal of Acquired Immune Deficiency Syndromes. 2013.
  0

• 4.

  2013

  David M. Knipe; Paul M. Lieberman; Jae U. Jung; Alison A. McBride; Kevin V. Morris; Melanie Ott; David Margolis; Amelia Nieto; Michael Nevels; Robin J. Parks; et al.

  Snapshots: Chromatin control of viral infection

  Virology. 2013;435(1):141-156.
  2

• 5.

  2013

  K.M. Barton; B.D. Burch; N. Soriano-Sarabia; D.M. Margolis

  Prospects for treatment of latent HIV

  Clinical Pharmacology and Therapeutics. 2013;93(1):46-56.
  1

• 6.

  2013

  Mehri S. Mckellar; Anna B. Cope; Cynthia L. Gay; Kara S. McGee; Joann D. Kuruc; Melissa G. Kerkau; Christopher B. Hurt; Susan A. Fiscus; Guido Ferrari; David M. Margolis; et al.

  Acute HIV-1 Infection in the southeastern United States: A cohort study

  AIDS Research and Human Retroviruses. 2013;29(1):121-128.
  0

• 7.

  2013

  Lu Zheng; Ronald J. Bosch; Ellen S. Chan; Sarah Read; Mary Kearney; David M. Margolis; John W. Mellors; Joseph J. Eron; Rajesh T. Gandhi

  Predictors of residual viraemia in patients on longterm suppressive antiretroviral therapy

  Antiviral Therapy. 2013;18(1):39-43.
  0

• 8.

  2012

  Camellia Banerjee; Nancie Archin; Daniel Michaels; Anna C. Belkina; Gerald V. Denis; James Bradner; Paola Sebastiani; David M. Margolis; Monty Montano

  BET bromodomain inhibition as a novel strategy for reactivation of HIV-1

  Journal of Leukocyte Biology. 2012;92(6):1147-1154.
  8

• 9.

  2012

  N.M. Archin; A.L. Liberty; A.D. Kashuba; S.K. Choudhary; J.D. Kuruc; A.M. Crooks; D.C. Parker; E.M. Anderson; M.F. Kearney; M.C. Strain; et al.

  Erratum: Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

  Nature. 2012;489(7416):460.
  0

• 10.

  2012

  Christian Melander; David M. Margolis

  Medicinal chemistry: Forcing an enemy into the open

  Nature Chemistry. 2012;4(9):692-693.
  0

• 11.

  2012

  P.W. Denton; T. Nochi; A. Lim; J.F. Krisko; F. Martinez-Torres; S.K. Choudhary; A. Wahl; R. Olesen; W. Zou; J.P. Di Santo; et al.

  IL-2 receptor γ-chain molecule is critical for intestinal T-cell reconstitution in humanized mice

  Mucosal Immunology. 2012;5(5):555-566.
  4

• 12.

  2012

  Steven G. Deeks; Brigitte Autran; Ben Berkhout; Monsef Benkirane; Scott Cairns; Nicolas Chomont; Tae-Wook Chun; Melissa Churchill; Michele Di Mascio; Christine Katlama; et al.

  Towards an HIV cure: A global scientific strategy

  Nature Reviews Immunology. 2012;12(8):607-614.
  17

• 13.

  2012

  N.M. Archin; A.L. Liberty; A.D. Kashuba; S.K. Choudhary; J.D. Kuruc; A.M. Crooks; D.C. Parker; E.M. Anderson; M.F. Kearney; M.C. Strain; et al.

  Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

  Nature. 2012;487(7408):482-485.
  26

• 14.

  2012

  Robert McLinden; Robert Paris; Victoria Polonis; Nicole Close; Zhaohui Su; Cecilia Shikuma; David Margolis; Jerome Kim

  Association of HIV neutralizing antibody with lower viral load after treatment interruption in a prospective trial (A5170)

  AIDS. 2012;26(11):1452.
  0

• 15.

  2012

  Nancie M. Archin; Naveen K. Vaidya; JoAnn D. Kuruc; Abigail L. Liberty; Ann Wiegand; Mary F. Kearney; Myron S. Cohen; John M. Coffin; Ronald J. Bosch; Cynthia L. Gay; et al.

  Immediate antiviral therapy appears to restrict resting CD4 ⁺ cell HIV-1 infection without accelerating the decay of latent infection

  Proceedings of the National Academy of Sciences of the United States of America. 2012;109(24):9523-9528.
  4

• 16.

  2012

  Rajesh T. Gandhi; Robert W. Coombs; Ellen S. Chan; Ronald J. Bosch; Lu Zheng; David M. Margolis; Sarah Read; Beatrice Kallungal; Ming Chang; Erin A. Goecker; et al.

  No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy

  Journal of Acquired Immune Deficiency Syndromes. 2012;59(3):229-235.
  6

• 17.

  2012

  Robert J. McLinden; Robert M. Paris; Victoria R. Polonis; Nicole C. Close; Zhaohui Su; Cecilia M. Shikuma; David M. Margolis; Jerome H. Kim

  Association of HIV neutralizing antibody with lower viral load after treatment interruption in a prospective trial (A5170)

  AIDS. 2012;26(1):1-9.
  1

• 18.

  2012

  Paul Denton; Rikke Olesen; Shailesh K. Choudhary; Nancy M. Archin; Angela Wahl; Michael D. Swanson; Morgan Chateau; Tomonori Nochi; John F. Krisko; Rae Ann Spagnuolo; et al.

  Generation of HIV latency in humanized BLT mice

  Journal of Virology. 2012;86(1):630-634.
  13

• 19.

  2012

  Shailesh K. Choudhary; Nancie M. Archin; Manzoor Cheema; Noelle P. Dahl; J. Victor Garcia; David M. Margolis

  Latent HIV-1 infection of resting CD4+ T Cells in the humanized Rag2 ^-/- γ _c^-/- mouse

  Journal of Virology. 2012;86(1):114-120.
  8

• 20.

  2011

  Hua-Xin Liao; Xi Chen; Supriya Munshaw; Ruijun Zhang; Dawn J. Marshall; Nathan Vandergrift; John F. Whitesides; Xiaozhi Lu; Jae-Sung Yu; Kwan-Ki Hwang; et al.

  Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

  Journal of Experimental Medicine. 2011;208(11):2237-2249.
  21

• 21.

  2011

  Michael J. Vinikoor; Yu-Tung Wong; David M. Margolis

  Herpes simplex virus type 2 mimicking necrotizing fasciitis

  Annals of Internal Medicine. 2011;155(8):567-568.
  0

• 22.

  2011

  Julia Friedman; Won-Kyung Cho; Chung K. Chu; Kara S. Keedy; Nancie M. Archin; David M. Margolis; Jonathan Karn

  Epigenetic silencing of HIV-1 by the histone H3 Lysine 27 methyltransferase enhancer of Zeste 2

  Journal of Virology. 2011;85(17):9078-9089.
  14

• 23.

  2011

  Sifei Xing; Cynthia K. Bullen; Neeta S. Shroff; Liang Shan; Hung-Chih Yang; Jordyn L. Manucci; Shridhar Bhat; Hao Zhang; Joseph B. Margolick; Thomas C. Quinn; et al.

  Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

  Journal of Virology. 2011;85(12):6060-6064.
  23

• 24.

  2011

  Jeffrey A. Anderson; Nancie M. Archin; William Ince; Daniel Parker; Ann Wiegand; John M. Coffin; JoAnn Kuruc; Joseph Eron; Ronald Swanstrom; David M. Margolis

  Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4 ⁺ T cells

  Journal of Virology. 2011;85(10):5220-5223.
  16

• 25.

  2011

  Cynthia L. Gay; Ashley J. Mayo; Chelu K. Mfalila; Haitao Chu; Anna C. Barry; Joann D. Kuruc; Kara S. McGee; Melissa Kerkau; Joe Sebastian; Susan A. Fiscus; et al.

  Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection

  AIDS. 2011;25(7):941-949.
  6

• 26.

  2011

  David M. Margolis

  Eradication therapies for HIV infection: Time to begin again

  AIDS Research and Human Retroviruses. 2011;27(4):347-353.
  13

• 27.

  2011

  Meagan O'Brien; Olivier Manches; Rachel Lubong Sabado; Sonia Jimenez Baranda; Yaming Wang; Isabelle Marie; Linda Rolnitzky; Martin Markowitz; David M. Margolis; David Levy; et al.

  Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype

  Journal of Clinical Investigation. 2011;121(3):1088-1101.
  23

• 28.

  2011

  Shailesh K. Choudhary; David M. Margolis

  Curing HIV: Pharmacologic approaches to target HIV-1 Latency

  Annual Review of Pharmacology and Toxicology. 2011;51:397-418.
  24

• 29.

  2011

  David M. Margolis

  Histone deacetylase inhibitors and HIV latency

  Current Opinion in HIV and AIDS. 2011;6(1):25-29.
  24

• 30.

  2011

  Cynthia Gay; Oliver Dibben; Jeffrey A. Anderson; Andrea Stacey; Ashley J. Mayo; Philip J. Norris; JoAnn D. Kuruc; Jesus F. Salazar-Gonzalez; Hui Li; Brandon F. Keele; et al.

  Cross-sectional detection of acute HIV infection: Timing of transmission, inflammation and antiretroviral therapy

  PLoS ONE. 2011;6(5).
  12

• 31.

  2010

  Rachel Lubong Sabado; Meagan O'Brien; Abhignya Subedi; Li Qin; Nan Hu; Elizabeth Taylor; Oliver Dibben; Andrea Stacey; Jacques Fellay; Kevin V. Shianna; et al.

  Evidence of dysregulation of dendritic cells in primary HIV infection

  Blood. 2010;116(19):3839-3852.
  43

• 32.

  2010

  Rajesh T. Gandhi; Lu Zheng; Ronald J. Bosch; Ellen S. Chan; David M. Margolis; Sarah Read; Beatrice Kallungal; Sarah Palmer; Kathy Medvik; Michael M. Lederman; et al.

  The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: A randomized controlled trial

  PLoS Medicine. 2010;7(8).
  62

• 33.

  2010

  Kimberly Smith; Lu Zheng; Ronald Bosch; David M. Margolis; Allan Tenorio; Laura Napolitano; Michael Saag; Elizabeth Connick; Barry Gross; Isaac Francis; et al.

  Erratum: Treatment with Recombinant Growth Hormone Is Associated with Modest Improvement in CD4 Lymphocyte Reconstitution in HIV-Infected Persons on Antiretroviral Therapy: Results of ACTG A5174 (AIDS Research and Human Retroviruses (2010) 26 (425-432))

  AIDS Research and Human Retroviruses. 2010;26(7):839.
  0

• 34.

  2010

  Kara S. Keedy; David M. Margolis

  Therapy for persistent HIV

  Trends in Pharmacological Sciences. 2010;31(5):206-211.
  10

• 35.

  2010

  K.R. Robertson; Z. Su; D.M. Margolis; A. Krambrink; D.V. Havlir; S. Evans; D.J. Skiest

  Neurocognitive effects of treatment interruption in stable HIV-positive patients in an observational cohort

  Neurology. 2010;74(16):1260-1266.
  33

• 36.

  2010

  Nancie M. Archin; Manzoor Cheema; Daniel Parker; Ann Wiegand; Ronald J. Bosch; John M. Coffin; Joseph Eron; Myron Cohen; David M. Margolis

  Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection

  PLoS ONE. 2010;5(2).
  37

• 37.

  2010

  David M. Margolis

  Mechanisms of HIV latency: An emerging picture of complexity

  Current HIV/AIDS Reports. 2010;7(1):37-43.
  27

• 38.

  2009

  Mary-Catherine Bowman; Nancie M. Archin; David M. Margolis

  Pharmaceutical approaches to eradication of persistent HIV infection

  Expert Reviews in Molecular Medicine. 2009;11.
  21

• 39.

  2009

  S. Munshaw; H. Liao; A. Dixon; X. Chen; A. Nagel; K. Derosa; R. Parks; J. Amos; J.F. Whitesides; D.J. Marshalls; et al.

  S021-04 OA. A large-scale analysis of immunoglobulin sequences derived from plasmablasts/plasma cells in acute HIV-1 infection subjects

  Retrovirology. 2009;6(SUPPL. 3):O4.
  0

• 40.

  2009

  L. Liao; X. Chen; A. Dixon; S. Munshaw; M. Moody; R. Zhang; A. Nagel; A. Foulger; K. Derosa; R. Parks; et al.

  P04-45. Characterization of the plasma cell repertoire in acute HIV-1 infection (AHI)

  Retrovirology. 2009;6(SUPPL. 3):P73.
  2

• 41.

  2009

  Nancie M. Archin; Kara S. Keedy; Amy Espeseth; Herbert Dang; Daria J. Hazuda; David M. Margolis

  Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

  AIDS. 2009;23(14):1799-1806.
  48

• 42.

  2009

  Shailesh K. Choudhary; Naser L. Rezk; William L. Ince; Manzoor Cheema; Liguo Zhang; Lishan Su; Ronald Swanstrom; Angela D. M. Kashuba; David M. Margolis

  Suppression of human immunodeficiency virus type 1 (HIV-1) viremia with reverse transcriptase and integrase inhibitors, CD4⁺ T-cell recovery, and viral rebound upon interruption of therapy in a new model for HIV treatment in the humanized Rag2^-/-γ_c^-/- mouse

  Journal of Virology. 2009;83(16):8254-8258.
  31

• 43.

  2009

  Marc C. Levesque; M. Anthony Moody; Kwan-Ki Hwang; Dawn J. Marshall; John F. Whitesides; Joshua D. Amos; Thaddeus C. Gurley; Sallie Allgood; Benjamin B. Haynes; Nathan A. Vandergrift; et al.

  Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

  PLoS Medicine. 2009;6(7).
  48

• 44.

  2009

  Kara S. Keedy; Nancie M. Archin; Adam T. Gates; Amy Espeseth; Daria J. Hazuda; David M. Margolis

  A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression

  Journal of Virology. 2009;83(10):4749-4756.
  47

• 45.

  2009

  Timothy J. Wilkin; John E. McKinnon; A. Gregory DiRienzo; Katie Mollan; Courtney V. Fletcher; David M. Margolis; Barbara Bastow; Gary Thal; William Woodward; Catherine Godfrey; et al.

  Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: Final 48-week clinical and virologic outcomes

  Journal of Infectious Diseases. 2009;199(6):866-871.
  34

• 46.

  2009

  Anthony J. Busti; Roger Bedimo; David M. Margolis; Dana S. Hardin

  Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir

  Journal of Investigative Medicine. 2009;56(2):539-544.
  12

• 47.

  2009

  Nancie M. Archin; Amy Espeseth; Daniel Parker; Manzoor Cheema; Daria Hazuda; David M. Margolis

  Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

  AIDS Research and Human Retroviruses. 2009;25(2):207-212.
  85

• 48.

  2009

  Douglas D. Richman; David M. Margolis; Martin Delaney; Warner C. Greene; Daria Hazuda; Roger J. Pomerantz

  The challenge of finding a cure for HIV infection

  Science. 2009;323(5919):1304-1307.
  241

• 49.

  2008

  Daniel J. Skiest; Amy Krambrink; Zhaohui Su; Kevin R. Robertson; David M. Margolis

  Improved measures of quality of life, lipid profile, and lipoatrophy after treatment interruption in HIV-infected patients with immune preservation: Results of ACTG 5170

  Journal of Acquired Immune Deficiency Syndromes. 2008;49(4):377-383.
  4

• 50.

  2008

  C. Bradley Hare; John Mellors; Amy Krambrink; Zhaohui Su; Daniel Skiest; David M. Margolis; Sheran S. Patel; Douglas Barnas; Lisa Frenkel; et al.

  Detection of nonnucleoside reverse-transcriptase inhibitor-resistant HIV-1 after discontinuation of virologically suppressive antiretroviral therapy

  Clinical Infectious Diseases. 2008;47(3):421-424.
  14

• 51.

  2008

  Maryanne T. Vahey; Zhining Wang; Zhaohui Su; Martin E. Nau; Amy Krambrink; Daniel J. Skiest; David M. Margolis

  CD4⁺ T-cell decline after the interruption of antiretroviral therapy in ACTG A5170 is predicted by differential expression of genes in the ras signaling pathway

  AIDS Research and Human Retroviruses. 2008;24(8):1047-1066.
  3

• 52.

  2008

  Nancy M Archin; Joseph J Eron; Sarah Palmer; Anne Hartmann-Duff; Jeffery A Martinson; Ann Wiegand; Nicholas Bandarenko; John L Schmitz; Ronald J Bosch; Alan L Landay; et al.

  Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells

  AIDS. 2008;22(10):1131-1135.
  58

• 53.

  2008

  Mary-Catherine Bowman; T. Eric Ballard; Christopher J. Ackerson; Daniel L. Feldheim; David M. Margolis; Christian Melander

  Inhibition of HIV fusion with multivalent gold nanoparticles

  Journal of the American Chemical Society. 2008;130(22):6896-6897.
  97

• 54.

  2008

  Shailesh K. Choudhary; Nancy M. Archin; David M. Margolis

  Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4⁺ T cells

  Journal of Infectious Diseases. 2008;197(8):1162-1170.
  31

• 55.

  2008

  Daniel J. Skiest; David M. Margolis

  Reply to Cooper et al.

  Journal of Infectious Diseases. 2008;197(5):775-776.
  0

• 56.

  2008

  Anthony J Busti; Roger Bedimo; David M Margolis; Dana S Hardin

  Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2008;56(2):539-544.
  7

• 57.

  2007

  David M. Margolis; A. Lisa Mukherjee; Courtney V. Fletcher; Evelyn Hogg; Debra Ogata-Arakaki; Tianna Petersen; David Rusin; Ana Martinez; John W. Mellors

  The use of β-D-2,6-diaminopurine dioxolane with or without mycophenolate mofetil in drug-resistant HIV infection

  AIDS. 2007;21(15):2025-2032.
  13

• 58.

  2007

  Guochun Jiang; Amy Espeseth; Daria J. Hazuda; David M. Margolis

  c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter

  Journal of Virology. 2007;81(20):10914-10923.
  78

• 59.

  2007

  David M. Margolis

  Treatment for lipoatrophy: Facing the real costs

  AIDS. 2007;21(13):1819-1820.
  4

• 60.

  2007

  David M. Margolis; Nancie M. Archin

  Eliminating persistent HIV infection: Getting to the end of the rainbow

  Journal of Infectious Diseases. 2007;195(12):1734-1736.
  4

• 61.

  2007

  Daniel J. Skiest; Zhaohui Su; Diane V. Havlir; Kevin R. Robertson; Robert W. Coombs; Pat Cain; Tianna Peterson; Amy Krambrink; Nasreen Jahed; Deborah McMahon; et al.

  Interruption of antiretroviral treatment in HIV-infected patients with preserved immune function is associated with a low rate of clinical progression: A prospective study by AIDS clinical trials group 5170

  Journal of Infectious Diseases. 2007;195(10):1426-1436.
  30

• 62.

  2007

  David M. Margolis

  Confronting proviral HIV infection

  Current HIV/AIDS Reports. 2007;4(2):60-64.
  2

• 63.

  2006

  Michael M. Lederman; Laura Smeaton; Kim Y. Smith; Benigno Rodriguez; Minya Pu; Hongying Wang; Anne Sevin; Pablo Tebas; Scott F. Sieg; Kathy Medvik; et al.

  Cyclosporin A provides no sustained immunologic benefit to persons with chronic HIV-1 infection starting suppressive antiretroviral therapy: Results of a randomized, controlled trial of the AIDS Clinical Trials Group A5138

  Journal of Infectious Diseases. 2006;194(12):1677-1685.
  16

• 64.

  2006

  David M. Margolis; Nancy M. Archin

  Attacking HIV provirus: Therapeutic strategies to disrupt persistent infection

  Infectious Disorders - Drug Targets. 2006;6(4):369-376.
  10

• 65.

  2006

  Roger Bedimo; R. Ghurani; M. Nsuami; D. Turner; M.-B. Kvanli; G. Brown; D. Margolis

  Lipid abnormalities in HIV/hepatitis C virus-coinfected patients

  HIV Medicine. 2006;7(8):530-536.
  15

• 66.

  2006

  Susan Swindells; A. Gregory DiRienzo; Timothy Wilkin; Courtney V. Fletcher; David M. Margolis; Gary D. Thal; Catherine Godfrey; Barbara Bastow; M. Graham Ray; Hongying Wang; et al.

  Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy after sustained virologic suppression

  Journal of the American Medical Association. 2006;296(7):806-814.
  66

• 67.

  2006

  Anthony J. Busti; J.P. Tsikouris; M.J. Peeters; S.R. Das; R.M. Canham; S.M. Abdullah; D.M. Margolis

  A prospective evaluation of the effect of atazanavir on the QTc interval and QTc dispersion in HIV-positive patients

  HIV Medicine. 2006;7(5):317-322.
  24

• 68.

  2006

  Rupinderjeet Kaur; Roger Bedimo; Mary Beth Kvanli; Diana Turner; Leslie Shaw; David Margolis

  A placebo-controlled pilot study of intensification of antiretroviral therapy with mycophenolate mofetil

  AIDS Research and Therapy. 2006;3(1).
  5

• 69.

  2006

  Vladimir Klichko; Nancy Archin; Rupinderjeet Kaur; Ginger Lehrman; David Margolis

  Hexamethylbisacetamide remodels the human immunodeficiency virus type 1 (HIV-1) promoter and induces Tat-independent HIV-1 expression but blunts cell activation

  Journal of Virology. 2006;80(9):4570-4579.
  26

• 70.

  2005

  Ginger Lehrman; Ian B. Hogue; Sarah Palmer; Cheryl Jennings; Celsa A. Spina; Ann Wiegand; Alan L. Landay; Robert W. Coombs; Douglas D. Richman; et al.

  Depletion of latent HIV-1 infection in vivo: A proof-of-concept study

  Lancet. 2005;366(9485):549-555.
  255

• 71.

  2005

  Loyda Ylisastigui; Rupinderjeet Kaur; Holly Johnson; Janet Volker; Guocheng He; Ulla Hansen; David Margolis

  Mitogen-activated protein kinases regulate LSF occupancy at the human immunodeficiency virus type 1 promoter

  Journal of Virology. 2005;79(10):5952-5962.
  12

• 72.

  2005

  Roger Bedimo; David M. Margolis

  Commentary on increased risk of prostate cancer among HIV-infected men

  American Journal of Urology Review. 2005;3(3):133-135.
  0

• 73.

  2005

  Rupinderjeet Kaur; Vladimir Klichko; David Margolis

  Ex vivo modeling of the effects of mycophenolic acid on HIV infection: Considerations for antiviral therapy

  AIDS Research and Human Retroviruses. 2005;21(2):116-124.
  10

• 74.

  2004

  Anthony J. Busti; Ronald G. Hall II; David M. Margolis

  Atazanavir for the treatment of human immunodeficiency virus infection

  Pharmacotherapy. 2004;24(12 I):1732-1747.
  61

• 75.

  2004

  Loyda Ylisastigui; Jason J. Coull; Victor C. Rucker; Christian Melander; Ronald J. Bosch; Scott J. Brodie; Lawrence Corey; Donald L. Sodora; Peter B. Dervan; et al.

  Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors

  Journal of Infectious Diseases. 2004;190(8):1429-1437.
  41

• 76.

  2004

  Ginger Lehrman; Loyda Ylisastigui; Ronald J. Bosch; David M. Margolis

  Interleukin-7 induces HIV type 1 outgrowth from peripheral resting CD4 ⁺ T cells [1]

  Journal of Acquired Immune Deficiency Syndromes. 2004;36(5):1103-1104.
  17

• 77.

  2004

  Loyda Ylisastigui; Nancie M. Archin; Ginger Lehrman; Ronald J. Bosch; David M. Margolis

  Coaxing HIV-1 from resting CD4 T cells: Histone deacetylase inhibition allows latent viral expression

  AIDS. 2004;18(8):1101-1108.
  111

• 78.

  2004

  Brian C. Weis; David Margolis; Shawn C. Burgess; Matthew E. Merritt; Holly Wise; A. Dean Sherry; Craig R. Malloy

  Glucose Production Pathways by ²H and ¹³C NMR in Patients with HIV-Associated Lipoatrophy

  Magnetic Resonance in Medicine. 2004;51(4):649-654.
  13

• 79.

  2003

  Peter J. Ruane; David M. Parenti; David M. Margolis; David H. Shepp; Timothy J. Babinchak; A.S. van Kempen; Teresa L. Kauf; Susan A. Danehower; Linda Yau; Siegrid M. Hessenthaler; et al.

  Compact quadruple therapy with the lamivudine/zidovudine combination tablet plus abacavir and efavirenz, followed by the lamivudine/zidovudine/abacavir triple nucleoside tablet plus efavirenz in treatment-naïve HIV-infected adults

  HIV Clinical Trials. 2003;4(4):231-243.
  9

• 80.

  2003

  Sharon Nachman; Soyeon Kim; James King; Elaine J. Abrams; David Margolis; Ann Petru; William Shearer; Elizabeth Smith; Jack Moye; Suzette Blanchard; et al.

  Safety and immunogenicity of a heptavalent pneumococcal conjugate vaccine in infants with human immunodeficiency virus type 1 infection

  Pediatrics. 2003;112(1 I):66-73.
  55

• 81.

  2003

  Shawn C. Burgess; Brian Weis; John G. Jones; Erin Smith; Matthew E. Merritt; David Margolis; A. Dean Sherry; Craig R. Malloy

  Noninvasive evaluation of liver metabolism by ²H and ¹³C NMR isotopomer analysis of human urine

  Analytical Biochemistry. 2003;312(2):228-234.
  37

• 82.

  2002

  Jason J. Coull; Guocheng He; Christian Melander; Victor C. Rucker; Peter B. Dervan; David M. Margolis

  Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides

  Journal of Virology. 2002;76(23):12349-12354.
  54

• 83.

  2002

  David M. Margolis; Stephen Kewn; Jason J. Coull; Loyda Ylisastigui; Diana Turner; Holly Wise; Mohammed M. Hossain; E. Randall Lanier; Leslie M. Shaw; David Back

  The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA

  Journal of Acquired Immune Deficiency Syndromes. 2002;31(1):45-49.
  58

• 84.

  2002

  Marc A. Tribble; Clark R. Gregg; David M. Margolis; Robin Amirkhan; James W. Smith

  Fatal ergotism induced by an HIV protease inhibitor [2]

  Headache. 2002;42(7):694-695.
  9

• 85.

  2002

  Kim A. Howes; Mark E. Pennesi; Izabela Sokal; Jill Church-Kopish; Ben Schmidt; David Margolis; Jeanne M. Frederick; Fred Rieke; Krzysztof Palczewski; et al.

  GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout mice

  EMBO Journal. 2002;21(7):1545-1554.
  66

• 86.

  2002

  Mohammad M. Hossain; Jason J. Coull; George L. Drusano; David M. Margolis

  Dose proportional inhibition of HIV-1 replication by mycophenolic acid and synergistic inhibition in combination with abacavir, didanosine, and tenofovir

  Antiviral Research. 2002;55(1):41-52.
  52

• 87.

  2002

  Guocheng He; David M. Margolis

  Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat

  Molecular and Cellular Biology. 2002;22(9):2965-2973.
  113

• 88.

  2002

  Guocheng He; Loyda Ylisastigui; David M. Margolis

  The regulation of HIV-1 gene expression: The emerging role of chromatin

  DNA and Cell Biology. 2002;21(10):697-705.
  32

• 89.

  2001

  M.M. Hossain; D.M. Margolis

  Inhibition of HIV replication by A77 1726, the active metabolite of leflunomide, in combination with pyrimidine nucleoside reverse transcriptase inhibitors [4]

  Journal of Acquired Immune Deficiency Syndromes. 2001;28(2):199-201.
  5

• 90.

  2001

  Jason J. Coull; Diana Turner; Thomas Melby; Michael R. Betts; Randall Lanier; David M. Margolis

  A pilot study of the use of mycophenolate mofetil as a component of therapy for multidrug-resistant HIV-1 infection

  Journal of Acquired Immune Deficiency Syndromes. 2001;26(5):423-434.
  44

• 91.

  2000

  Fiorenza Cocchi; Anthony L. DeVico; Robert Yarchoan; Robert Redfield; Farley Cleghorn; William A. Blattner; Alfredo Garzino-Demo; Sandra Colombini-Hatch; David Margolis; et al.

  Higher macrophage inflammatory protein (MIP)-1α and MIP-1β levels from CD8⁺ T cells are associated with asymptomatic HIV-1 infection

  Proceedings of the National Academy of Sciences of the United States of America. 2000;97(25):13812-13817.
  81

• 92.

  2000

  Jason J. Coull; Fabio Romerio; Jian-Min Sun; Janet L. Volker; Katherine M. Galvin; James R. Davie; Yang Shi; Ulla Hansen; David M. Margolis

  The human factors YY1 and LSF repress the human immunodeficiency virus type 1 long terminal repeat via recruitment of histone Deacetylase 1

  Journal of Virology. 2000;74(15):6790-6799.
  149

• 93.

  1999

  A. Heredia; D. Margolis; D. Oldach; R. Hazen; N. Le; R. Redfield

  Abacavir in combination with the inosine monophosphate dehydrogenase (IMPDH)-inhibitor mycophenolic acid is active against multidrug-resistant HIV-1 [1]

  Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 1999;22(4):406-407.
  33

• 94.

  1999

  David Margolis; Alonso Heredia; Jariyanart Gaywee; David Oldach; George Drusano; Robert Redfield

  Abacavir and mycophenolic acid, an inhibitor of inosine monophosphate dehydrogenase, have profound and synergistic anti-HIV activity

  Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology. 1999;21(5):362-370.
  88

• 95.

  1999

  Masako Moriuchi; Hiroyuki Moriuchi; David M. Margolis; Anthony S. Fauci

  USF/c-Myc enhances, while Yin-Yang 1 suppresses, the promoter activity of CXCR4, a coreceptor for HIV-1 entry

  Journal of Immunology. 1999;162(10):5986-5992.
  41

• 96.

  1998

  Louis Flamand; Richard W. Crowley; Paolo Lusso; Sandra Colombini-Hatch; David M. Margolis; Robert C. Gallo

  Activation of CD8⁺ T lymphocytes through the T cell receptor turns on CD4 gene expression: Implications for HIV pathogenesis

  Proceedings of the National Academy of Sciences of the United States of America. 1998;95(6):3111-3116.
  108

• 97.

  1998

  F. Romerio; M.N. Gabriel; D.M. Margolis

  Erratum: Repression of human immunodeficiency virus type 1 through the novel cooperation of human factors YY1 and LSF (Journal of Virology 71:12 (9382))

  Journal of Virology. 1998;72(2):1709.
  0

• 98.

  1997

  Fabio Romerio; Matthew N. Gabriel; David M. Margolis

  Repression of human immunodeficiency virus type 1 through the novel cooperation of human factors YY1 and LSF

  Journal of Virology. 1997;71(12):9375-9382.
  53

• 99.

  1997

  D.M. Margolis; M.T. Collins

  A 74-year-old man with persistent fevers.

  Maryland medical journal (Baltimore, Md. : 1985). 1997;46(10):524-529.
  1

• 100.

  1997

  Norbert Bräu; Howard L. Leaf; Rosemary L. Wieczorek; David M. Margolis

  Severe hepatitis in three AIDS patients treated with indinavir [6]

  Lancet. 1997;349(9056):924-925.
  107

• 101.

  1996

  C. Chougnet; D. Margolis; A.L. Landay; H.A. Kessler; G.M. Shearer

  Contribution of prostaglandin (PG) E2 to the IL-12 defect in HIV-infected (HIV+) patients

  FASEB Journal. 1996;10(6):A1056.
  0

• 102.

  1996

  C.A. Chougnet; D. Margolis; A.L. Landay; H.A. Kessler; G.M. Shearer

  Contribution of prostaglandin E₂ to the interleukin-12 defect in HIV-infected patients [3]

  AIDS. 1996;10(9):1043-1045.
  8

• 103.

  1996

  M. Holodniy; D. Margolis; R. Carroll; J. Todd; L. Mole

  Quantitative relationship between platelet count and plasma virion HIV RNA [4]

  AIDS. 1996;10(2):232-233.
  4

• 104.

  1995

  Mark Holodniy; Larry Mole; Dan Margolis; Jeremy Moss; Helin Dong; Eric Boyer; Mickey Urdea; Janice Kolberg; Scott Eastman

  Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudine-didanosine combination therapy

  Journal of Virology. 1995;69(6):3510-3516.
  34

• 105.

  1994

  David M. Margolis; Mohan Somasundaran; Michael R. Green

  Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production

  Journal of Virology. 1994;68(2):905-910.
  62

• 106.

  1993

  D.M. Margolis; J.M. Ostrove; S.E. Straus

  HSV-1 activation of HIV-1 transcription is augmented by a cellular protein that binds near the initiator element

  Virology. 1993;192(1):370-374.
  23

• 107.

  1993

  S.E. Straus; B. Savarese; M. Tigges; A.G. Freifeld; P.R. Krause; D.M. Margolis; J.L. Meier; D.P. Paar; S.F. Adair; et al.

  Induction and enhancement of immune responses to herpes simplex virus type 2 in humans by use of a recombinant glycoprotein D vaccine

  Journal of Infectious Diseases. 1993;167(5):1045-1052.
  36

• 108.

  1993

  J.A. Clark; D.M. Margolis

  A cutaneous lesion in a patient with AIDS: An unusual presentation of infection due to Mycobacterium avium complex

  Clinical Infectious Diseases. 1993;16(4):555-557.
  9

• 109.

  1992

  D.M. Margolis; A.B. Rabson; S.E. Straus; J.M. Ostrove

  Transactivation of the HIV-1 LTR by HSV-1 immediate-early genes

  Virology. 1992;186(2):788-791.
  56

• 110.

  1990

  D.M. Margolis; D.A. Melnick; D.W. Alling; J.I. Gallin

  Trimethoprim-sulfamethoxazole prophylaxis in the management of chronic granulomatous diseases

  Journal of Infectious Diseases. 1990;162(3):723-726.
  103

• 111.

  1987

  David M. Margolis

  Interferon inactivator(s) in patients with aids and aids-unrelated Kaposi's Sarcoma

  The American Journal of Medicine. 1987;82(6):1278.
  0

• 112.

  1985

  Marian Willinger; David M. Margolis

  Effect of the weaver (wv) mutation on cerebellar neuron differentiation. I. Qualitative observations of neuron behavior in culture

  Developmental Biology. 1985;107(1):156-172.
  12

• 113.

  1985

  Marian Willinger; David M. Margolis

  Effect of the weaver (wv) mutation on cerebellar neuron differentiation. II. Quantitation of neuron behavior in culture

  Developmental Biology. 1985;107(1):173-179.
  4

• 114.

  1983

  R.L. Sidman; M. Willinger; D.M. Margolis

  Mouse weaver mutation affects granule cell neurite growth in vitro

  Birth Defects: Original Article Series. 1983;19(4):189-200.
  0

• 115.

  1981

  M. Willinger; D.M. Margolis; R.L. Sidman

  Neuronal differentiation in cultures of weaver (wv) mutant mouse cerebellum

  Journal of Supramolecular and Cellular Biochemistry. 1981;17(1):79-86.
  5